Congenital EP Featured Articles of April 2017


Pediatric Cardiac and EP Reviews of April 2017 Manuscripts


Pacemaker and Defibrillator Implantation in Patients with Transposition of the Great Arteries

Grubb AF, Shah G, Aziz PF, Krasuski RA

The Journal of Innovations in Cardiac Rhythm Management, 8 (2017), 2658-2664


Take Home Points:


  • Cardiac implantable device implantation in TGA substrates presents unique challenges both at implant and throughout follow-up.
  • This study does not apply to arterial switch patients.
  • Despite differences in indications for implantable devices and age at device implant between d- and l-TGA patients, both TGA groups unfortunately appear to have similar progressions in the development of heart failure with its associated morbidity and mortality.
  • Utilization of current published guidelines for primary prevention ICD implantation has shortcomings when applied to TGA substrates and would benefit from updated evidence and experience with ICDs in TGA patients to guide and individualize this treatment option in this unique patient population.


chang-philip-1780821827Commentary from Dr. Philip Chang (Los Angeles), section editor of Congenital Heart Surgery Journal Watch: Article summary:

Grubb et al presented a retrospective review of their single-center experience with cardiac implantable electronic devices (CIEDs) in d- and l-TGA patients with systemic RVs.  The study looked at all TGA patients with CIEDs cared for at their institution over an 18-year period.  All patients had systemic right ventricles and all patients had undergone biventricular repair approaches, with single-ventricle variants and those with repairs to restore systemic morphologic left ventricular circulation excluded from analysis.  In total, 63 patients were identified (34 d-TGA, 29 l-TGA).  The authors performed detailed chart review for each subject to determine initial device implant timing/age, development of heart failure, and variables associated with ICD follow-up including defibrillation thresholds and shocks.








Study limitations include single-center inclusivity and retrospective design.  The authors did not provide more in-depth detail pertaining to implant approaches, CIED pocket site (left vs. right chest for transvenous devices, which could have implications in ICD defibrillation function), or CIED-related complications.   Several patients reportedly had CRT devices, but no detail was provided in terms of the indications for CRT or implant approach.


Reviewer perspective and thoughts for pediatric/CHD EP:

While it is commonly recognized and even expected that TGA patients will require CIED implantation, primarily for pacing indications, it has been quite some time since the topic of CIED utilization and benefit in TGA patients has been studied.  As such, the authors are commended for reviewing their data and presenting their experience, which is quite valuable for our community.  The study definitely highlights the importance of considering multi-institutional pooling of data and experience.  Furthermore, while the growth of the atrial switched d-TGA population is diminishing, there is still a considerable population of these patients, along with a growing number of adult l-TGA patients that should motivate greater awareness of the use of CIEDs in these very unique ACHD subgroups.

There is little debate in the indications for and benefits of pacing in TGA substrates and the authors’ findings of more predominant pacing for sinus node disease in d-TGA and AV block in l-TGA isn’t novel.  It remains unclear as to the role of CRT for wide QRS, heart block, or dyssynchrony in TGA, and more specifically its feasibility and effectiveness in primary systemic RV resynchronization.  With the advent of and interest in His-bundle pacing, the feasibility of this method of pacing in d- vs. l-TGA would be interesting to explore in terms of technical considerations and long-term benefit.  The finding that no primary prevention ICD patients received appropriate shocks was interesting, but not entirely surprising.  This certainly raises the question of the appropriateness of applying standard guidelines for ICD implantation to the TGA population and while some published data exists for risk stratification in d-TGA, greater evidence is needed to guide ICD therapy, particularly for primary prevention indications, in these patients.   Finally, with the subcutaneous ICD as a contemporary implant option, it will also be interesting to see how the balance between implant indication and “ease” of device implant will change.


It is sobering to see that both d- and l-TGA patients with systemic RVs progress in very similar fashions to develop heart failure and its associated clinical sequelae and mortality.  This shared finding between d- and l-TGA patients highlights the unique and highly complex substrate in which CIEDs are being applied, as well as the multifactorial process involved in the near-universal fate of the systemic RV in these TGA patients.




Lone Pediatric Atrial Fibrillation in the United States: Analysis of Over 1500 Cases

El-Assaad I, Al-Kindi SG, Saarel EV, Aziz PF

Pediatr Cardiol April 2017 (DOI: 10.1007/s00246-017-1608-7)


Take home points:

  • Lone atrial fibrillation is a rare arrhythmia condition among pediatric patients.
  • Increasing age and obesity appear associated with higher incidence of lone atrial fibrillation though evidence indicating direct causality is lacking.
  • While complications such as thromboembolic events are rare in pediatric lone atrial fibrillation, their incidence is not ignorable. However, treatment recommendations and practice patterns are inconsistent.


Commentary from Dr. Philip Chang (Los Angeles, CA) section editor of Congenital Heart Surgery Journal WatchThere has been much recent interest in atrial fibrillation in pediatric and young adult patients, particularly as it pertains to risk factors for its development as well as treatment in patients with significant or symptomatic recurrences and in the setting of CHD.  Despite this interest, studies with large sample sizes are lacking in order to better understand its incidence, clinical sequelae, treatment options and response, and long-term outcomes, particularly in otherwise healthy individuals.  The current study from El-Assaad et al provides a descriptive analysis of the largest cohort of young patients with lone atrial fibrillation in the United States.

The authors sought to evaluate risk factors and short-term outcomes of pediatric lone atrial fibrillation, simply defined as atrial fibrillation occurring in the absence of cardiac and systemic diseases.  They utilized a privately managed national healthcare database, Explorys, from which they were able to query and determine an incidence of pediatric lone atrial fibrillation, other variables that may be associated with its diagnosis, and clinical sequelae over a 17-year period (1999-2016).  The database was created from de-identified data provided by 360 hospitals in all 50 US states and over 300,000 providers.

Results of querying the Explorys database yielded nearly 8 million children, with 1910 children linked to an atrial fibrillation diagnosis.  Of these patients, 1750 children met the definition of lone atrial fibrillation.  This resulted in a calculated pediatric lone AF incidence of 7.5 in 100,000 persons at risk.  Nearly 10% of these patients also had concomitant diagnosis of SVT but further characterization of this could not be determined from the dataset variables.  The authors found relatively low percentages of antiarrhythmic use (5%), aspirin or warfarin for anticoagulation (7% and 5%, respectively), and electrical cardioversion (3%).  Older patients tended to be prescribed aspirin or warfarin more frequently compared to younger aged cohorts.


Multivariate analysis showed increasing age, male gender, and obesity to be associated with risk of lone AF.  Increasing age was also associated with increased risk of AF recurrence within 1 month of initial episode.  Interestingly, among patients 15-19 years of age, nearly 20% experienced AF recurrence.  The authors also found that 2% of patients experienced a stroke within 1 year of lone AF diagnosis.  Following exclusion of other concomitant diagnoses including sepsis, hypertension, hypertensive crisis, drug abuse, stimulant use, cancer, renal impairment, sleep apena, respiratory failure, and bone marrow transplant, a total of 1580 patient remained.  Among these patients, a male predominance was noted (61%), and most episodes of lone AF occurred in the 15-19 years age group (58%).  Those in the oldest age cohort had recurrence rates spanning 15-22% from 1 month up to 1 year after the initial event.  In this lone AF subset, 1% of patients had a stroke within 1 year of lone AF diagnosis.



Study limitations include limited available variables in the database and inability to control for the quality and accuracy of the data provided.  For example, the authors noted that they were unable to review ECGs to confirm AF diagnosis or echocardiograms to evaluate chamber size and that some patients could have been misclassified as having AF in the first place.  Recurrence rates could have been overestimated if a single AF diagnosis reappeared on more than 1 occasion.  They also noted that the dataset itself has not been directly validated for pediatric studies, though adult studies have demonstrated its validity.  It is unclear as to why nearly 10% of the originally classified “lone AF” patients were excluded given other systemic diseases to come to the subgroup of 1580 patients that were further analyzed for lone AF incidence and recurrence.  By the authors’ definition, these patients would not have met a pure lone AF diagnosis given these concomitant conditions, many of which can certainly increase the risk of arrhythmias (AF being one of them).  If the subgroup patients were used to calculate incidence, the lone AF incidence would be even lower.  Finally, the authors did not have further details relating to concomitant SVT in the 10% of patients identified and there was no long-term data regarding treatment efficacy (antiarrhythmics or catheter ablation), prognosis, and outcomes.


Reviewer perspective and thoughts for pediatric/CHD EP:

This study is an excellent example of the use of large scale databases to evaluate otherwise rare conditions.  As such, it provides a faster, and perhaps more accurate, assessment of pediatric lone AF incidence, as well as general approaches to management, complications, and recurrence.  The study is obviously limited by the quality and accuracy of data entered into the database itself.

This study’s finding of the association between lone AF and obesity, male gender, and increasing age is helpful and consistent with previous publications noting these potential associations that had substantially smaller patient cohorts.  The association with obesity is likely multifactorial.  Obesity is frequently associated with other cardiovascular conditions including hypertension, diastolic dysfunction, and left atrial distension and pressure loading, though interestingly, the association between obesity and lone AF was apparently made in the study after excluding for these other systemic diseases.  It is possible that these other systemic diseases were under-reported in the dataset and echo data was not available to assess for evidence of diastolic dysfunction or left atrial abnormalities.  Obesity is also frequently associated with obstructive sleep apnea, which is increasingly recognized as having a strong association with arrhythmia risk including AF (though again, the study largely excluded patients with concomitant diagnoses of AF and sleep apnea).  The authors noted familial lone AF as a possible important contributor, and the genetics of AF remains an important area of ongoing research.

Several important findings from this study that are important for the pediatric EP community to be aware of is the low incidence of pediatric lone AF that is found and which is likely more reflective of its true incidence in the general pediatric population.  Furthermore, based on the study’s results, there appears to be a fairly high recurrence rate (up to 20% in the oldest age cohort) as well as a low but very concerning incidence of stroke.  Both of these appeared to be present in the setting of low utilization of antiarrhythmic agents and anticoagulation.  In fact, the stroke incidence that was noted in this study corresponded to an equivalent CHADS2VASc score that would qualify patients to receive anticoagulation with either warfarin or NOACs.  This study’s findings show that pediatric lone AF may not be as benign of a condition as some may think and that these patients require aggressive and close follow-up to address or prevent recurrences and to reduce AF-related complications.

CHD EP April 2017


  1. Atrial undersensing secondary to quiet timer blanking in pediatric and congenital heart disease patients.

von Alvensleben JC, Schaffer M, Brateng C, Collins KK.

Pacing Clin Electrophysiol. 2017 Apr 24. doi: 10.1111/pace.13101. [Epub ahead of print]

PMID: 28436549

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  1. Percutaneous Ventricular Assist Device for Circulatory Support During Ablation of Atrial Tachycardias in Patients With Fontan Circulation.

Hendriks A, De Vries L, Witsenburg M, Yap SC, Van Mieghem N, Szili-Torok T.

Rev Esp Cardiol (Engl Ed). 2017 Apr 18. pii: S1885-5857(17)30170-6. doi: 10.1016/j.rec.2017.03.010. [Epub ahead of print] English, Spanish. No abstract available.

PMID: 28431884

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  1. The electrical heart axis and ST events in fetal monitoring: A post-hoc analysis following a multicentre randomised controlled trial.

Vullings R, Verdurmen KMJ, Hulsenboom ADJ, Scheffer S, de Lau H, Kwee A, Wijn PFF, Amer-Wåhlin I, van Laar JOEH, Oei SG.

PLoS One. 2017 Apr 14;12(4):e0175823. doi: 10.1371/journal.pone.0175823. eCollection 2017.

PMID: 28410419 Free PMC Article

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  1. Sudden cardiac death in adults with congenital heart disease: does QRS-complex fragmentation discriminate in structurally abnormal hearts?

Vehmeijer JT, Koyak Z, Bokma JP, Budts W, Harris L, Mulder BJ, de Groot JR.

Europace. 2017 Apr 10. doi: 10.1093/europace/eux044. [Epub ahead of print]

PMID: 28402450

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  1. Post mortem therapy from a subcutaneous ICD: What is the mechanism?

Wiles BM, Fitzsimmons SJ, Roberts PR.

Pacing Clin Electrophysiol. 2017 Apr 4. doi: 10.1111/pace.13089. [Epub ahead of print] No abstract available.

PMID: 28374449

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  1. Lone Pediatric Atrial Fibrillation in the United States: Analysis of Over 1500 Cases.

El-Assaad I, Al-Kindi SG, Saarel EV, Aziz PF.

Pediatr Cardiol. 2017 Apr 3. doi: 10.1007/s00246-017-1608-7. [Epub ahead of print]

PMID: 28374048

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  1. [Clinical features and outcomes of radiofrequency catheter ablation of atrial flutter in children].

Jiang H, Li XM, Zhang Y, Liu HJ, Li MT, Ge HY.

Zhonghua Er Ke Za Zhi. 2017 Apr 2;55(4):267-271. doi: 10.3760/cma.j.issn.0578-1310.2017.04.007. Chinese.

PMID: 28441822

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  1. [Brief interpretation of “the Pediatric and Congenital Electrophysiology Society (PACES)and the Heart Rhythm Society (HRS) expert consensus statement on the use of catheter ablation in children and patients with congenital heart disease].

Wu JJ, Li F.

Zhonghua Er Ke Za Zhi. 2017 Apr 2;55(4):256-259. doi: 10.3760/cma.j.issn.0578-1310.2017.04.004. Chinese. No abstract available.

PMID: 28441820

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  1. Non-fluoroscopic cardiac ablation of neonates with CHD.

Bigelow AM, Arnold BS, Padrutt GC, Clark JM.

Cardiol Young. 2017 Apr;27(3):592-596. doi: 10.1017/S1047951116001554. Epub 2016 Oct 21.

PMID: 27766996

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  1. What Is the Best Age for Diagnostic Prediction of Pediatric Long-QT Syndrome With a Borderline QT Interval?

Miyazaki A, Doi H.

Circ Arrhythm Electrophysiol. 2017 Apr;10(4). pii: e005119. doi: 10.1161/CIRCEP.117.005119. No abstract available.

PMID: 28356308

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  1. Left ventricular dysfunction is associated with frequent premature ventricular complexes and asymptomatic ventricular tachycardia in children.

Bertels RA, Harteveld LM, Filippini LH, Clur SA, Blom NA.

Europace. 2017 Apr 1;19(4):617-621. doi: 10.1093/europace/euw075.

PMID: 28431063

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  1. Outcomes of lead extraction in young adults.

El-Chami MF, Sayegh MN, Patel A, El-Khalil J, Desai Y, Leon AR, Merchant FM.

Heart Rhythm. 2017 Apr;14(4):537-540. doi: 10.1016/j.hrthm.2017.01.030. Epub 2017 Feb 16.

PMID: 28189822

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  1. Avoiding sports-related sudden cardiac death in children with congenital channelopathy : Recommendations for sports activities.

Lang CN, Steinfurt J, Odening KE.

Herz. 2017 Apr;42(2):162-170. doi: 10.1007/s00059-017-4549-2.

PMID: 28233036

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  1. Corrigendum to ‘Ventricular tachyarrhythmia during pregnancy in women with heart disease: Data from the ROPAC, a registry from the European Society of Cardiology’ [Int. J. Cardiol. 220 (2016) 131-136].

Ertekin E, van Hagen IM, Salam AM, Ruys TP, Johnson MR, Popelova J, Parsonage WA, Ashour Z, Shotan A, Oliver JM, Veldtman GR, Hall R, Roos-Hesselink JW.

Int J Cardiol. 2017 Apr 1;232:348. doi: 10.1016/j.ijcard.2017.01.077. Epub 2017 Jan 27. No abstract available.

PMID: 28139301 Free Article

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  1. Utility and safety of the SafeSept™ transseptal guidewire for electrophysiology studies with catheter ablation in pediatric and congenital heart disease.

Knadler JJ, Anderson JB, Chaouki AS, Czosek RJ, Connor C, Knilans TK, Spar DS.

J Interv Card Electrophysiol. 2017 Apr;48(3):369-374. doi: 10.1007/s10840-017-0224-z. Epub 2017 Jan 14.

PMID: 28091832

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  1. Evaluation of Prolonged QT Interval: Structural Heart Disease Mimicking Long QT Syndrome.

Weissler-Snir A, Gollob MH, Chauhan V, Care M, Spears DA.

Pacing Clin Electrophysiol. 2017 Apr;40(4):417-424. doi: 10.1111/pace.13040. Epub 2017 Mar 16.

PMID: 28155223

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  1. Arrhythmias in Adults with Congenital Heart Disease: What Are Risk Factors for Specific Arrhythmias?

Loomba RS, Buelow MW, Aggarwal S, Arora RR, Kovach J, Ginde S.

Pacing Clin Electrophysiol. 2017 Apr;40(4):353-361. doi: 10.1111/pace.12983. Epub 2017 Feb 27.

PMID: 27987225

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  1. Clinical Application of the QRS-T Angle for the Prediction of Ventricular Arrhythmias in Patients with the Fontan Palliation.

Tran TV, Cortez D.

Pediatr Cardiol. 2017 Apr 29. doi: 10.1007/s00246-017-1618-5. [Epub ahead of print]

PMID: 28456831

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  1. Fetal cardiac time intervals in healthy pregnancies – an observational study by fetal ECG (Monica Healthcare System).

Wacker-Gussmann A, Plankl C, Sewald M, Schneider KM, Oberhoffer R, Lobmaier SM.

J Perinat Med. 2017 Apr 28. pii: /j/jpme.ahead-of-print/jpm-2017-0003/jpm-2017-0003.xml. doi: 10.1515/jpm-2017-0003. [Epub ahead of print]

PMID: 28453441

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  1. Electrophysiological effects of anthracyclines in adult survivors of pediatric malignancy.

Markman TM, Ruble K, Loeb D, Chen A, Zhang Y, Beasley GS, Thompson WR, Nazarian S.

Pediatr Blood Cancer. 2017 Apr 28. doi: 10.1002/pbc.26556. [Epub ahead of print]

PMID: 28453898

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  1. Prospective Study of Adenosine on Atrioventricular Nodal Conduction in Pediatric and Young Adult Patients After Heart Transplant.

Flyer JN, Zuckerman WA, Richmond ME, Anderson BR, Mendelsberg TG, McAllister JM, Liberman L, Addonizio LJ, Silver ES.

Circulation. 2017 Apr 27. pii: CIRCULATIONAHA.117.028087. doi: 10.1161/CIRCULATIONAHA.117.028087. [Epub ahead of print]

PMID: 28450351

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  1. Mid-Term Follow-up of School-Aged Children With Borderline Long QT Interval.

Miyazaki A, Sakaguchi H, Matsumura Y, Hayama Y, Noritake K, Negishi J, Tsuda E, Miyamoto Y, Aiba T, Shimizu W, Kusano K, Shiraishi I, Ohuchi H.

Circ J. 2017 Apr 25;81(5):726-732. doi: 10.1253/circj.CJ-16-0991. Epub 2017 Feb 18.

PMID: 28216547 Free Article

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  1. Transesophageal and invasive electrophysiologic evaluation in children with Wolff-Parkinson-White pattern.

Koca S, Pac FA, Kavurt AV, Cay S, Mihcioglu A, Aras D, Topaloglu S.

Pacing Clin Electrophysiol. 2017 Apr 24. doi: 10.1111/pace.13100. [Epub ahead of print]

PMID: 28436586

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  1. The role of echocardiography in fetal tachyarrhythmia diagnosis. A burden for the pediatric cardiologist and a review of the literature.

Gozar L, Marginean C, Toganel R, Muntean I.

Med Ultrason. 2017 Apr 22;19(2):232-235. doi: 10.11152/mu-892.

PMID: 28440361 Free Article

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  1. Automated T-wave analysis can differentiate acquired QT prolongation from congenital long QT syndrome.

Sugrue A, Noseworthy PA, Kremen V, Bos JM, Qiang B, Rohatgi RK, Sapir Y, Attia ZI, Brady P, Caraballo PJ, Asirvatham SJ, Friedman PA, Ackerman MJ.

Ann Noninvasive Electrocardiol. 2017 Apr 21. doi: 10.1111/anec.12455. [Epub ahead of print]

PMID: 28429460

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  1. Cardiac Transplantation in Children and Adolescents with Long QT Syndrome.

Kelle AM, Bos JM, Etheridge SP, Cannon BC, Bryant RM, Johnson JN, Ackerman MJ.

Heart Rhythm. 2017 Apr 14. pii: S1547-5271(17)30451-4. doi: 10.1016/j.hrthm.2017.04.023. [Epub ahead of print]

PMID: 28416468

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  1. Lidocaine Attenuation Testing: An In Vivo Investigation of Putative LQT3-Associated Variants in the SCN5A-Encoded Sodium Channel.

Heather N Anderson MD, Bos JM, Kapplinger JD, Meskill JM, Ye D, Ackerman MJ.

Heart Rhythm. 2017 Apr 12. pii: S1547-5271(17)30448-4. doi: 10.1016/j.hrthm.2017.04.020. [Epub ahead of print]

PMID: 28412158

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  1. The KCNH2-IVS9-28A/G mutation causes aberrant isoform expression and hERG trafficking defect in cardiomyocytes derived from patients affected by Long QT Syndrome type 2.

Mura M, Mehta A, Ramachandra CJ, Zappatore R, Pisano F, Ciuffreda MC, Barbaccia V, Crotti L, Schwartz PJ, Shim W, Gnecchi M.

Int J Cardiol. 2017 Apr 12. pii: S0167-5273(17)30298-X. doi: 10.1016/j.ijcard.2017.04.038. [Epub ahead of print]

PMID: 28433559

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  1. Evaluation of QTc in Rett syndrome: Correlation with age, severity, and genotype.

Crosson J, Srivastava S, Bibat GM, Gupta S, Kantipuly A, Smith-Hicks C, Myers SM, Sanyal A, Yenokyan G, Brenner J, Naidu SR.

Am J Med Genet A. 2017 Apr 10. doi: 10.1002/ajmg.a.38191. [Epub ahead of print]

PMID: 28394409

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  1. Noninvasive predictors of perioperative atrial arrhythmias in patients with tetralogy of Fallot undergoing pulmonary valve replacement.

Cortez D, Barham W, Ruckdeschel E, Sharma N, McCanta AC, von Alvensleben J, Sauer WH, Collins KK, Kay J, Patel S, Nguyen DT.

Clin Cardiol. 2017 Apr 10. doi: 10.1002/clc.22707. [Epub ahead of print]

PMID: 28394443 Free Article

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  1. Tachycardia cycle and atrioventricular nodal conduction properties in children with supraventricular tachycardia.

Mills M, Dubin AM, Motonaga KS, Ceresnak SR.

Pacing Clin Electrophysiol. 2017 Apr 6. doi: 10.1111/pace.13083. [Epub ahead of print] No abstract available.

PMID: 28383202

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  1. To the Editors-Risk factors for complications in the implantation of epicardial pacemakers in neonates and infants.

Kean AC, Rodefeld M.

Heart Rhythm. 2017 Apr 5. pii: S1547-5271(17)30314-4. doi: 10.1016/j.hrthm.2017.03.021. [Epub ahead of print] No abstract available.

PMID: 28389305

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  1. Interpreting Incidentally Identified Variants in Genes Associated With Catecholaminergic Polymorphic Ventricular Tachycardia in a Large Cohort of Clinical Whole-Exome Genetic Test Referrals.

Landstrom AP, Dailey-Schwartz AL, Rosenfeld JA, Yang Y, McLean MJ, Miyake CY, Valdes SO, Fan Y, Allen HD, Penny DJ, Kim JJ.

Circ Arrhythm Electrophysiol. 2017 Apr;10(4). pii: e004742. doi: 10.1161/CIRCEP.116.004742.

PMID: 28404607

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  1. Effect of Age and Sex on the QTc Interval in Children and Adolescents With Type 1 and 2 Long-QT Syndrome.

Vink AS, Clur SB, Geskus RB, Blank AC, De Kezel CC, Yoshinaga M, Hofman N, Wilde AA, Blom NA.

Circ Arrhythm Electrophysiol. 2017 Apr;10(4). pii: e004645. doi: 10.1161/CIRCEP.116.004645.

PMID: 28356306

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  1. J-Wave syndromes expert consensus conference report: Emerging concepts and gaps in knowledge.

Antzelevitch C, Yan GX, Ackerman MJ, Borggrefe M, Corrado D, Guo J, Gussak I, Hasdemir C, Horie M, Huikuri H, Ma C, Morita H, Nam GB, Sacher F, Shimizu W, Viskin S, Wilde AAM.

Europace. 2017 Apr 1;19(4):665-694. doi: 10.1093/europace/euw235. No abstract available.

PMID: 28431071

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  1. Corrigendum to ‘Ventricular tachyarrhythmia during pregnancy in women with heart disease: Data from the ROPAC, a registry from the European Society of Cardiology‘ [Int. J. Cardiol. 220 (2016) 131-136].

Ertekin E, van Hagen IM, Salam AM, Ruys TP, Johnson MR, Popelova J, Parsonage WA, Ashour Z, Shotan A, Oliver JM, Veldtman GR, Hall R, Roos-Hesselink JW.

Int J Cardiol. 2017 Apr 1;232:348. doi: 10.1016/j.ijcard.2017.01.077. Epub 2017 Jan 27. No abstract available.

PMID: 28139301 Free Article

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  1. Precision Cardiovascular Medicine: State of Genetic Testing.

Giudicessi JR, Kullo IJ, Ackerman MJ.

Mayo Clin Proc. 2017 Apr;92(4):642-662. doi: 10.1016/j.mayocp.2017.01.015. Review.

PMID: 28385198

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  1. Early Repolarization in Normal Adolescents is Common.

Ahmed H, Czosek RJ, Spar DS, Knilans TK, Anderson JB.

Pediatr Cardiol. 2017 Apr;38(4):864-872. doi: 10.1007/s00246-017-1594-9. Epub 2017 Apr 3.

PMID: 28367598

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  1. Arrhythmias After Fontan Operation with Intra-atrial Lateral Tunnel Versus Extra-cardiac Conduit: A Systematic Review and Meta-analysis.

Li D, Fan Q, Hirata Y, Ono M, An Q.

Pediatr Cardiol. 2017 Apr;38(4):873-880. doi: 10.1007/s00246-017-1595-8. Epub 2017 Mar 7.

PMID: 28271152

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  1. Lateral Atrial Tunnel Fontan Operation Predisposes to the Junctional Rhythm.

Januszewska K, Schuh A, Lehner A, Dalla-Pozza R, Malec E.

Pediatr Cardiol. 2017 Apr;38(4):712-718. doi: 10.1007/s00246-017-1571-3. Epub 2017 Feb 10.

PMID: 28184977

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  1. Effects of Triple Cryoenergy Application on Lesion Formation and Coronary Arteries in the Developing Myocardium.

Krause U, Abreu da Cunha FD, Backhoff D, Jacobshagen C, Klehs S, Schneider HE, Paul T.

Pediatr Cardiol. 2017 Apr;38(4):663-668. doi: 10.1007/s00246-016-1564-7. Epub 2017 Jan 11.

PMID: 28078383

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  1. ECGs in the ED.

Tanel RE.

Pediatr Emerg Care. 2017 Apr;33(4):309-310. doi: 10.1097/PEC.0000000000001149. No abstract available.

PMID: 28353534

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  1. [Our experience in the diagnosis and treatment of postural orthostatic tachycardia syndrome, vasovagal syncope, and inappropriate sinus tachycardia in children].

Ugan Atik S, Dedeoğlu R, Koka A, Öztunç F.

Turk Kardiyol Dern Ars. 2017 Apr;45(3):227-234. doi: 10.5543/tkda.2017.36517. Turkish.

PMID: 28429690 Free Article

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CHD Surgery Featured Articles of March 2017

CHD Surgery March 2017


  1. Acute kidney injury and fluid overload in infants and children after cardiac surgery.

Kwiatkowski DM, Krawczeski CD.

Pediatr Nephrol. 2017 Mar 30. doi: 10.1007/s00467-017-3643-2. [Epub ahead of print]




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  1. Significant survival advantage of high pulmonary vein index and the presence of native pulmonary artery in pulmonary atresia with ventricular septal defect and major aortopulmonary collateral arteries: results from preoperative computed tomography angiography.

Jia Q, Cen J, Zhuang J, Zhong X, Liu X, Li J, Liang C, Huang M.

Eur J Cardiothorac Surg. 2017 Mar 28. doi: 10.1093/ejcts/ezx064. [Epub ahead of print]




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  1. National trends and variability in blood utilization in paediatric cardiac surgery.

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  1. Dehiscence of a pulmonary bioprosthesis with a focal dissection of the pulmonary artery in a patient withcongenitalpulmonic stenosis.

Yucel E, Bhatt A, Mihos CG, Ghoshhajra BB, DeFaria Yeh D.

Echocardiography. 2017 Mar 27. doi: 10.1111/echo.13502. [Epub ahead of print]




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  1. Surgical planning for a complex double-outlet right ventricle using 3D printing.

Bhatla P, Tretter JT, Chikkabyrappa S, Chakravarti S, Mosca RS.

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  1. Near-infrared spectroscopy as a predictor of clinical deterioration: a case report of two infants with duct-dependentcongenital heart disease.

Mebius MJ, Sarvaas GJ, Wolthuis DW, Bartelds B, Kneyber MC, Bos AF, Kooi EM.

BMC Pediatr. 2017 Mar 16;17(1):79. doi: 10.1186/s12887-017-0839-3.




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  1. Anesthesia in adults withcongenital heart disease.

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  1. Incorporating Comorbidity Within Risk Adjustment for UK Pediatric Cardiac Surgery.

Brown KL, Rogers L, Barron DJ, Tsang V, Anderson D, Tibby S, Witter T, Stickley J, Crowe S, English K, Franklin RC, Pagel C.

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  1. Improving Risk Adjustment for Mortality After Pediatric Cardiac Surgery: The UK PRAiS2 Model.

Rogers L, Brown KL, Franklin RC, Ambler G, Anderson D, Barron DJ, Crowe S, English K, Stickley J, Tibby S, Tsang V, Utley M, Witter T, Pagel C.

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  1. Decellularized Cryopreserved Allografts as Off-the-Shelf Allogeneic Alternative forHeartValve Replacement: In Vitro Assessment Before Clinical Translation.

Iop L, Paolin A, Aguiari P, Trojan D, Cogliati E, Gerosa G.

J Cardiovasc Transl Res. 2017 Mar 9. doi: 10.1007/s12265-017-9738-0. [Epub ahead of print]




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  1. Translational Challenges in Cardiovascular Tissue Engineering.

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  1. Single coronary artery and neonatal arterial switch operation: early and long-term outcomes†.

Gerelli S, Pontailler M, Rochas B, Angeli E, Van Steenberghe M, Bonnet D, Vouhé P, Raisky O.

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  1. Contemporary cardiac surgery for adults withcongenital heart disease.

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  1. Outcomes following implantation of mechanical circulatory support in adults withcongenital heart disease: An analysis of the Interagency Registry for Mechanically Assisted Circulatory Support (INTERMACS).

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  1. Prophylactic levosimendan for the prevention of low cardiac output syndrome and mortality in paediatric patients undergoing surgery forcongenital heart disease.

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  1. Popular HybridCongenitalHeart Procedures without Cardiopulmonary Bypass.

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  1. Long-term survival after the Fontan operation: Twenty years of experience at a single center.

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  1. Improved long-term outcomes in double-inlet left ventricle and tricuspid atresia with transposed great arteries: systemic outflow tract obstruction present at birth defines long-term outcome.

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Eur J Cardiothorac Surg. 2017 Mar 4. doi: 10.1093/ejcts/ezx022. [Epub ahead of print]




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  1. Successful cardiac transplantation outcomes in patients with adultcongenital heart disease.

Menachem JN, Golbus JR, Molina M, Mazurek JA, Hornsby N, Atluri P, Fuller S, Birati EY, Kim YY, Goldberg LR, Wald JW.

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  1. Long-Term Outcome of Patients With Complete Atrioventricular Septal Defect Combined With the Tetralogy of Fallot: Staged Repair Is Not Inferior to Primary Repair.

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  1. Two-dimensional right ventricular strain by speckle tracking for assessment of longitudinal right ventricular function after paediatriccongenital heart diseasesurgery.

Karsenty C, Hadeed K, Dulac Y, Semet F, Alacoque X, Breinig S, Leobon B, Acar P, Hascoet S.

Arch Cardiovasc Dis. 2017 Mar;110(3):157-166. doi: 10.1016/j.acvd.2016.09.003. Epub 2016 Dec 27.




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  1. Health-related quality of life in children with surgery for CHD: a study from the Swedish National Registry forCongenital Heart Disease.

Svensson B, Idvall E, Nilsson F, Liuba P.

Cardiol Young. 2017 Mar;27(2):333-343. doi: 10.1017/S1047951116000585. Epub 2016 May 26.




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  1. Alterations in antioxidant and oxidant status of children after on-pump surgery for cyanotic and acyanoticcongenitalheart diseases.

Altin FH, Yildirim HA, Tanidir IC, Yildiz O, Kahraman MZ, Ozturk E, Celebi SB, Kyaruzi M, Bakir İ.

Cardiol Young. 2017 Mar;27(2):325-332. doi: 10.1017/S1047951116000573. Epub 2016 May 19.




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  1. Clinical significance of serum cortisol levels following surgery forcongenital heart disease.

Teagarden AM, Mastropietro CW.

Cardiol Young. 2017 Mar;27(2):318-324. doi: 10.1017/S104795111600055X. Epub 2016 Apr 29.




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  1. Hydrodynamic Assessment of Aortic Valves Prepared from Porcine Small Intestinal Submucosa.

Ramaswamy S, Lordeus M, Mankame OV, Valdes-Cruz L, Bibevski S, Bell SM, Baez I, Scholl F.

Cardiovasc Eng Technol. 2017 Mar;8(1):30-40. doi: 10.1007/s13239-016-0290-x. Epub 2016 Dec 19.




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  1. Single-center outcomes of combinedheartand liver transplantation in the failing Fontan.

D’Souza BA, Fuller S, Gleason LP, Hornsby N, Wald J, Krok K, Shaked A, Goldberg LR, Pochettino A, Olthoff KM, Kim YY.

Clin Transplant. 2017 Mar;31(3). doi: 10.1111/ctr.12892. Epub 2017 Feb 4.




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  1. Decreased biventricular longitudinal strain shortly aftercongenitalheart defect surgery.

de Boer JM, Kuipers IM, Klitsie LM, Blom NA, Ten Harkel AD.

Echocardiography. 2017 Mar;34(3):446-452. doi: 10.1111/echo.13456. Epub 2017 Feb 6.




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  1. Systemic right ventricular morphology in the early postoperative course after extracardiac Fontan operation: is there still a need for special care?

Nordmeyer S, Rohder M, Nordmeyer J, Miera O, Peters B, Cho MY, Photiadis J, Berger F, Ovroutski S.

Eur J Cardiothorac Surg. 2017 Mar 1;51(3):483-489. doi: 10.1093/ejcts/ezw374.




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  1. Glial fibrillary acidic protein plasma levels are correlated with degree of hypothermia during cardiopulmonary bypass incongenital heart diseasesurgery.

Vedovelli L, Padalino M, D’Aronco S, Stellin G, Ori C, Carnielli VP, Simonato M, Cogo P.

Interact Cardiovasc Thorac Surg. 2017 Mar 1;24(3):436-442. doi: 10.1093/icvts/ivw395.




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  1. Surgical management of double outlet right ventricle with aortopulmonary window.

Hou C, Sihag V, Ling Y, An Q.

J Card Surg. 2017 Mar;32(3):203-205. doi: 10.1111/jocs.13102.




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  1. Extubation Failure after Neonatal Cardiac Surgery: A Multicenter Analysis.

Mastropietro CW, Cashen K, Grimaldi LM, Narayana Gowda KM, Piggott KD, Wilhelm M, Gradidge E, Moser EA, Benneyworth BD, Costello JM.

J Pediatr. 2017 Mar;182:190-196.e4. doi: 10.1016/j.jpeds.2016.12.028. Epub 2017 Jan 4.




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  1. Gastrointestinal complications associated with the surgical treatment ofheartdiseasein children.

Ferguson LP, Gandiya T, Kaselas C, Sheth J, Hasan A, Gabra HO.

J Pediatr Surg. 2017 Mar;52(3):414-419. doi: 10.1016/j.jpedsurg.2016.10.052. Epub 2016 Nov 14.




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  1. The impact of cardiac risk factors on short-term outcomes for children undergoing a Ladd procedure.

Putnam LR, Anderson KT, Tsao K, Kao LS, Lugo JA, Lally KP, Kawaguchi AL.

J Pediatr Surg. 2017 Mar;52(3):390-394. doi: 10.1016/j.jpedsurg.2016.09.064. Epub 2016 Oct 21.




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  1. Natural history of nonimmune-mediated thrombocytopenia and acute kidney injury in pediatric open-heartsurgery.

Tew S, Fontes ML, Greene NH, Kertai MD, Ofori-Amanfo G, Jaquiss RD, Lodge AJ, Ames WA, Homi HM, Machovec KA, Jooste EH.

Paediatr Anaesth. 2017 Mar;27(3):305-313. doi: 10.1111/pan.13063. Epub 2017 Jan 18.




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  1. Prevalence and Risk Factors for Pericardial Effusions Requiring Readmission After Pediatric Cardiac Surgery.

Elias MD, Glatz AC, O’Connor MJ, Schachtner S, Ravishankar C, Mascio CE, Cohen MS.

Pediatr Cardiol. 2017 Mar;38(3):484-494. doi: 10.1007/s00246-016-1540-2. Epub 2016 Nov 30.




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  1. Perioperative Near-Infrared Spectroscopy Monitoring in Neonates WithCongenital Heart Disease: Relationship of Cerebral Tissue Oxygenation Index Variability With Neurodevelopmental Outcome.

Spaeder MC, Klugman D, Skurow-Todd K, Glass P, Jonas RA, Donofrio MT.

Pediatr Crit Care Med. 2017 Mar;18(3):213-218. doi: 10.1097/PCC.0000000000001056.




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  1. Left Ventricular Retraining and Double Switch in Patients With Congenitally Corrected Transposition of the Great Arteries.

Ibrahimiye AN, Mainwaring RD, Patrick WL, Downey L, Yarlagadda V, Hanley FL.

World J Pediatr Congenit Heart Surg. 2017 Mar;8(2):203-209. doi: 10.1177/2150135116683939.




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  1. Nineteen Years of AdultCongenitalHeart Surgery in a Single Center.

Perinpanayagam M, Larsen SH, Emmertsen K, Møller MB, Hjortdal VE.

World J Pediatr Congenit Heart Surg. 2017 Mar;8(2):182-188. doi: 10.1177/2150135116682454.




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  1. Hemolysis During Open-HeartSurgery With Vacuum-Assisted Venous Drainage at Different Negative Pressures in Pediatric Patients Weighing Less Than 10 kilograms.

Kwak JG, Lee J, Park M, Seo YJ, Lee CH.

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  1. Anomalous Pulmonary Venous Connection With an Intraparenchymal Course.

Campanale CM, Banka P, Sanders SP.

World J Pediatr Congenit Heart Surg. 2017 Mar;8(2):210-214. doi: 10.1177/2150135116682468. Epub 2016 Dec 30.




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  1. Superior Vena Cava Banding to Facilitate Unilateral Bidirectional Glenn Operation in Patients With Single VentricleHeartDisease and Bilateral Superior Caval Veins.

Schwartz MC, Nykanen D, DeCampli W, Pourmoghadam K.

World J Pediatr Congenit Heart Surg. 2017 Mar;8(2):215-219. doi: 10.1177/2150135116679824. Epub 2016 Dec 7.




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  1. Survival of Three Neonates WithCongenitalDiaphragmatic Hernia and d-Transposition of the Great Arteries.

Blancha VL, Ratner V, Aspelund G, Chai P, Levasseur S, Krishnan U, Bacha E, Krishnamurthy G.

World J Pediatr Congenit Heart Surg. 2017 Mar;8(2):239-241. doi: 10.1177/2150135116632509. Epub 2016 Jul 7.




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  1. Endoventriculoplasty of the Left Ventricle forCongenitalDiverticulum.

Soynov IA, Sinelnikov YS, Nichay NR, Omelchenko AY, Kornilov IA.

World J Pediatr Congenit Heart Surg. 2017 Mar;8(2):227-230. doi: 10.1177/2150135115625204. Epub 2016 Jul 8.




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  1. Acute kidney injury and fluid overload in infants and children after cardiac surgery.

Kwiatkowski DM, Krawczeski CD.

Pediatr Nephrol. 2017 Mar 30. doi: 10.1007/s00467-017-3643-2. [Epub ahead of print]




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  1. An Alternative Strategy for Bridge-to-Transplant/Recovery in Small Children with Dilated Cardiomyopathy.

Mets G, Panzer J, De Wolf D, Bové T.

Pediatr Cardiol. 2017 Mar 29. doi: 10.1007/s00246-017-1610-0. [Epub ahead of print] Review.




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  1. Reducing PediatricSternal Wound Infections: A Quality Improvement Project.

Delgado-Corcoran C, Van Dorn CS, Pribble C, Thorell EA, Pavia AT, Ward C, Smout R, Bratton SL, Burch PT.

Pediatr Crit Care Med. 2017 Mar 27. doi: 10.1097/PCC.0000000000001135. [Epub ahead of print]




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  1. Interstage Weight Gain Is Associated With Survival After First-Stage Single-Ventricle Palliation.

Evans CF, Sorkin JD, Abraham DS, Wehman B, Kaushal S, Rosenthal GL.

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  1. Hypoplastic Left Heart Syndrome is not Associated with Worse Clinical or Neurodevelopmental Outcomes Than Other Cardiac Pathologies After the Norwood-Sano Operation.

Martin BJ, De Villiers Jonker I, Joffe AR, Bond GY, Acton BV, Ross DB, Robertson CM, Rebeyka IM, Atallah J.

Pediatr Cardiol. 2017 Mar 24. doi: 10.1007/s00246-017-1598-5. [Epub ahead of print]




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  1. The Effects of Center Volume on Mortality in PediatricHeart Transplantation- The Rest of the Story.

Canter CE.

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  1. Concomitant pulsatile and continuous flow VAD in biventricular and univentricular physiology: a comparison study with a numerical model.

Di Molfetta A, Ferrari G, Iacobelli R, Filippelli S, Guccione P, Fresiello L, Perri G, Amodeo A.

Int J Artif Organs. 2017 Mar 16;40(2):74-81. doi: 10.5301/ijao.5000562. Epub 2017 Feb 11.




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  1. Gothic aortic arch and cardiac mechanics in young patients after arterial switch operation for d-transposition of the great arteries.

Di Salvo G, Bulbul Z, Pergola V, Issa Z, Siblini G, Muhanna N, Galzerano D, Fadel B, Al Joufan M, Al Fayyadh M, Al Halees Z.

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  1. Implications and outcomes of cardiac grafts refused by pediatriccenters but transplanted by adult centers.

Zafar F, Rizwan R, Lorts A, Bryant R 3rd, Tweddell JS, Chin C, Morales DL.

J Thorac Cardiovasc Surg. 2017 Mar 11. pii: S0022-5223(17)30413-0. doi: 10.1016/j.jtcvs.2016.12.071. [Epub ahead of print]




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  1. Feasibility and interpretation of global longitudinal strain imaging in pediatricheart transplant recipients.

Wisotzkey BL, Jorgensen NW, Albers EL, Kemna MS, Boucek RJ, Kronmal RA, Law YM, Bhat AH.

Pediatr Transplant. 2017 Mar 10. doi: 10.1111/petr.12909. [Epub ahead of print]




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  1. Biventricular impact of mild to moderate pulmonary valve stenosis in fetal life.

Guirado L, Crispi F, Masoller N, Bennasar M, Marimon E, Carretero J, Gratacós E, Martínez JM, Friedberg MK, Gómez O.

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  1. Impact of Heart Transplantation on the Functional Status of US Children With End-Stage Heart Failure.

Peng DM, Zhang Y, Rosenthal DN, Palmon M, Chen S, Kaufman BD, Maeda K, Hollander SA, McDonald N, Smoot LB, Bernstein D, Almond CS.

Circulation. 2017 Mar 7;135(10):939-950. doi: 10.1161/CIRCULATIONAHA.115.016520. Epub 2017 Jan 24.




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  1. Importance of multidisciplinary management for pulmonary atresia, ventricular septal defect, major aorto-pulmonary collateral arteries and completely absent central pulmonary arteries.

Hoashi T, Yazaki S, Kagisaki K, Kitano M, Shimada M, Shiraishi I, Ichikawa H.

Gen Thorac Cardiovasc Surg. 2017 Mar 4. doi: 10.1007/s11748-017-0765-1. [Epub ahead of print]




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  1. Dynamic Changes in Aortic Vascular Stiffness in Patients Bridged to Transplant With Continuous-Flow Left Ventricular Assist Devices.

Patel AC, Dodson RB, Cornwell WK 3rd, Hunter KS, Cleveland JC Jr, Brieke A, Lindenfeld J, Ambardekar AV.

JACC Heart Fail. 2017 Mar 4. pii: S2213-1779(17)30046-X. doi: 10.1016/j.jchf.2016.12.009. [Epub ahead of print]




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  1. Femoral Vein Homograft as Right Ventricle to Pulmonary Artery Conduit in Stage 1 Norwood Operation.

Kumar TK, Briceno-Medina M, Sathanandam S, Joshi VM, Knott-Craig CJ.

Ann Thorac Surg. 2017 Mar 2. pii: S0003-4975(16)31819-7. doi: 10.1016/j.athoracsur.2016.11.078. [Epub ahead of print]




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  1. Functional status of United States children supported with a left ventricular assist device at heart transplantation.

Bulic A, Maeda K, Zhang Y, Chen S, McElhinney DB, Dykes JC, Hollander AM, Hollander SA, Murray J, Reinhartz O, Gowan MA, Rosenthal DN, Almond CS.

J Heart Lung Transplant. 2017 Mar 2. pii: S1053-2498(17)31675-3. doi: 10.1016/j.healun.2017.02.024. [Epub ahead of print]




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  1. Genomic Contraindications for Heart Transplantation.

Char DS, Lázaro-Muñoz G, Barnes A, Magnus D, Deem MJ, Lantos JD.

Pediatrics. 2017 Mar 2. pii: e20163471. doi: 10.1542/peds.2016-3471. [Epub ahead of print]




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  1. Inferior Outcomes on the Waiting List in Low-Volume PediatricHeart Transplant Centers.

Rana A, Fraser CD, Scully BB, Heinle JS, McKenzie ED, Dreyer WJ, Kueht M, Liu H, Brewer ED, Rosengart TK, O’Mahony CA, Goss JA.

Am J Transplant. 2017 Mar 1. doi: 10.1111/ajt.14252. [Epub ahead of print]




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  1. The Role of Echocardiography and Intracardiac Exploration in the Evaluation of Candidacy for Biventricular Repair in Patients With Borderline Left Heart Structures.

Mery CM, Nieto RM, De León LE, Morris SA, Zhang W, Colquitt JL, Adachi I, Kane LC, Heinle JS, McKenzie ED, Fraser CD Jr.

Ann Thorac Surg. 2017 Mar;103(3):853-861. doi: 10.1016/j.athoracsur.2016.07.043. Epub 2016 Oct 4.




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  1. Neonatal Ebstein repair-where are we now?

Wackel PL, Dearani JA, Cetta F.

Ann Transl Med. 2017 Mar;5(5):109. doi: 10.21037/atm.2017.01.19. No abstract available.




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  1. Application of a Lumped Parameter Model to Study the Feasibility of Simultaneous Implantation of a Continuous Flow Ventricular Assist Device (VAD) and a Pulsatile Flow VAD in BIVAD Patients.

Di Molfetta A, Ferrari G, Iacobelli R, Filippelli S, Fresiello L, Guccione P, Toscano A, Amodeo A.

Artif Organs. 2017 Mar;41(3):242-252. doi: 10.1111/aor.12911.




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  1. Pediatricheart transplant for unresectable primary cardiac tumor.

Prakash Rajakumar A, Ejaz Ahmed S, Varghese R, Kothandam S, Murmu UC, Sethuratnam R.

Asian Cardiovasc Thorac Ann. 2017 Mar;25(3):207-209. doi: 10.1177/0218492315614160. Epub 2016 Jul 11.




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  1. Anomalous left coronary artery from the pulmonary artery discovered following total anomalous pulmonary venous return repair: a rare entity.

Patel ND, Badran S, Kung G.

Cardiol Young. 2017 Mar;27(2):385-387. doi: 10.1017/S1047951116001220. Epub 2016 Aug 30.




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  1. Health-related quality of life in children with surgery for CHD: a study from the Swedish National Registry for Congenital Heart Disease.

Svensson B, Idvall E, Nilsson F, Liuba P.

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  1. Alterations in antioxidant and oxidant status of children after on-pump surgery for cyanotic and acyanotic congenital heart diseases.

Altin FH, Yildirim HA, Tanidir IC, Yildiz O, Kahraman MZ, Ozturk E, Celebi SB, Kyaruzi M, Bakir İ.

Cardiol Young. 2017 Mar;27(2):325-332. doi: 10.1017/S1047951116000573. Epub 2016 May 19.




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  1. Early and late outcomes after surgical management of congenital vascular rings.

François K, Panzer J, De Groote K, Vandekerckhove K, De Wolf D, De Wilde H, Marchau F, De Caluwe W, Benatar A, Bové T.

Eur J Pediatr. 2017 Mar;176(3):371-377. doi: 10.1007/s00431-017-2850-y. Epub 2017 Jan 13.




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Select item 28109039 252.


  1. Erratum to: Impact of varied center volume categories on volume-outcome relationship in children receiving ECMO for heart operations.

Rettiganti M, Seib PM, Robertson MJ, Wilcox A, Gupta P.

J Artif Organs. 2017 Mar;20(1):102. doi: 10.1007/s10047-016-0934-5. No abstract available.




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Select item 27932703 270.


  1. Left ventricular assist device as destination therapy in cardiac end-stage dystrophinopathies: Midterm results.

Perri G, Filippelli S, Adorisio R, Iacobelli R, Iodice F, Testa G, Paglietti MG, D’Amario D, Massetti M, Amodeo A.

J Thorac Cardiovasc Surg. 2017 Mar;153(3):669-674. doi: 10.1016/j.jtcvs.2016.08.016. Epub 2016 Aug 28.




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Select item 28247338 289.


  1. Institution of Veno-arterial Extracorporeal Membrane Oxygenation Does Not Lead to Increased Wall Stress in Patients with Impaired Myocardial Function.

Koth AM, Axelrod DM, Reddy S, Roth SJ, Tacy TA, Punn R.

Pediatr Cardiol. 2017 Mar;38(3):539-546. doi: 10.1007/s00246-016-1546-9. Epub 2016 Dec 22.




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Select item 27995292 308.


  1. Right Ventricular Dysfunction as an Echocardiographic Measure of Acute Rejection Following Heart Transplantation in Children.

Aggarwal S, Blake J, Sehgal S.

Pediatr Cardiol. 2017 Mar;38(3):442-447. doi: 10.1007/s00246-016-1533-1. Epub 2016 Nov 23.




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Select item 27878333 319.


  1. Central Venous to Arterial CO2 Difference After Cardiac Surgery in Infants and Neonates.

Rhodes LA, Erwin WC, Borasino S, Cleveland DC, Alten JA.

Pediatr Crit Care Med. 2017 Mar;18(3):228-233. doi: 10.1097/PCC.0000000000001085.




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Select item 28107262 322.


  1. Heart transplantation in children with intellectual disability.

Hollander SA.

Pediatr Transplant. 2017 Mar;21(2). doi: 10.1111/petr.12864. No abstract available.




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Select item 28097735 332.


  1. Autoimmune enteropathy and hepatitis in pediatricheart transplant recipient.

Lewis K, Butts R, Antonio Quiros J, Hudspeth M, Twombley K, Savage A, Self S, Burnette A, Sun S.

Pediatr Transplant. 2017 Mar;21(2). doi: 10.1111/petr.12877. Epub 2017 Jan 17.




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Select item 27933693 333.


  1. Heart transplantation in children with intellectual disability: An analysis of the UNOS database.

Goel AN, Iyengar A, Schowengerdt K, Fiore AC, Huddleston CB.

Pediatr Transplant. 2017 Mar;21(2). doi: 10.1111/petr.12858. Epub 2016 Dec 9.




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Select item 27801533 334.


  1. Current Practices in the Timing of Stage 2 Palliation.

Meza JM, Jaquiss RD, Anderson BR, Moga MA, Kirklin JK, Sarris G, Williams WG, McCrindle BW; Congenital Heart Surgeons’ Society..

World J Pediatr Congenit Heart Surg. 2017 Mar;8(2):135-141. doi: 10.1177/2150135116677253.




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Select item 28329461 345.


  1. Effect of Prime Blood Storage Duration on Clinical Outcome After PediatricCardiac Surgery.

Bishnoi AK, Garg P, Patel K, Solanki P, Surti J, Solanki A, Shah K, Patel S.

World J Pediatr Congenit Heart Surg. 2017 Mar;8(2):166-173. doi: 10.1177/2150135116682451.




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Select item 27549734 347.


  1. Successful Surgical Excision of a Large Cardiac Fibroma in an Asymptomatic Child.

Borodinova O, Ostras O, Raad T, Yemets I.

World J Pediatr Congenit Heart Surg. 2017 Mar;8(2):235-238. doi: 10.1177/2150135116634287. Epub 2016 Jun 23.




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Select item 27095117 349.


  1. Simultaneous total cavopulmonary connection and cardiac re-synchronisation therapy.

Nakanishi K, Kawasaki S, Amano A.

Cardiol Young. 2017 Mar 20:1-4. doi: 10.1017/S1047951117000257. [Epub ahead of print]




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Select item 28318457 9.


  1. Growth of left ventricular outflow tract and predictors of future re-intervention after repair for ventricular septal defect and aortic arch obstruction.

Jijeh A, Ismail M, Alhabshan F.

Cardiol Young. 2017 Mar 16:1-6. doi: 10.1017/S104795111700018X. [Epub ahead of print]




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Select item 28300009 12.


  1. The Total Inotrope Exposure Score: an extension of the Vasoactive Inotrope Score as a predictor of adverse outcomes after paediatric cardiac surgery.

Bangalore H, Gaies M, Ocampo EC, Heinle JS, Guffey D, Minard CG, Checchia P, Shekerdemian LS.

Cardiol Young. 2017 Mar 13:1-7. doi: 10.1017/S1047951116002602. [Epub ahead of print]




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Select item 28287055 16.


  1. Congenital pulmonary lymphangiectasia and early mortality after stage 1 reconstruction procedures.

Herrmann JL, Irons ML, Mascio CE, Rychik J, Spray TL, Gaynor JW, Pogoriler JE.

Cardiol Young. 2017 Mar 13:1-5. doi: 10.1017/S1047951117000348. [Epub ahead of print]




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Select item 28279232 17.


  1. Transposition with atypical coronary pattern: the Aubert technique.

Pita-Fernández A, González-López MT, Gil-Jaurena JM.

Cardiol Young. 2017 Mar 6:1-4. doi: 10.1017/S1047951117000063. [Epub ahead of print]




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Select item 28260544 28.


  1. Aortic arch advancement for type A interrupted aortic arch with persistent fifth aortic arch type B.

Binsalamah ZM, Chen P, McKenzie ED.

Cardiol Young. 2017 Mar 6:1-4. doi: 10.1017/S1047951117000051. [Epub ahead of print]




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Select item 28260540 31.


  1. An alternative technique for Fontan completion in patients with widely separated connections of the inferior systemic veins to the atrial mass.

Pomè G, Ghedira F, Keizman E.

Cardiol Young. 2017 Mar;27(2):398-401. doi: 10.1017/S1047951116001311. Epub 2016 Aug 30.




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Select item 28081726 38.


  1. Alterations in antioxidant and oxidant status of children after on-pump surgery for cyanotic and acyanotic congenital heart diseases.

Altin FH, Yildirim HA, Tanidir IC, Yildiz O, Kahraman MZ, Ozturk E, Celebi SB, Kyaruzi M, Bakir İ.

Cardiol Young. 2017 Mar;27(2):325-332. doi: 10.1017/S1047951116000573. Epub 2016 May 19.




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Select item 27161361 55.


  1. Clinical significance of serum cortisol levels following surgery for congenital heart disease.

Teagarden AM, Mastropietro CW.

Cardiol Young. 2017 Mar;27(2):318-324. doi: 10.1017/S104795111600055X. Epub 2016 Apr 29.




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Select item 27125520 57.


  1. Paediatric cardiac surgery in a peripheral European region: is a joint programme a safe alternative to regionalisation?

Iacona GM, Giamberti A, Abella RF, Pomè G, Agredo J, Mendieta SG, Forcano A, Sobrado C, Suaréz J, Peñate S, Melián A, Volo M, González R, Antúnez ML, Falcón HL, Cabrera FJ, Rubio C, Fernández J, Suárez P, Perera C, Frigiola A.

Cardiol Young. 2017 Mar;27(2):273-283. doi: 10.1017/S1047951116000469. Epub 2016 Apr 18.




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Select item 27086493 61.


  1. Surgical Management of Absent Pulmonary Valve Syndrome.

Saritas B.

World J Pediatr Congenit Heart Surg. 2017 Mar;8(2):248. doi: 10.1177/2150135117692720. No abstract available.




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Select item 28329455 10.


  1. Denton Arthur Cooley, MD, and the Dawn of Congenital Heart Surgery.

Fraser CD Jr, Fraser CD 3rd.

World J Pediatr Congenit Heart Surg. 2017 Mar;8(2):127-129. doi: 10.1177/2150135117698459. No abstract available.




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Select item 28329454 11.


  1. Reply to Surgical Management of Absent Pulmonary Valve Syndrome.

Jonas RA.

World J Pediatr Congenit Heart Surg. 2017 Mar;8(2):248-249. doi: 10.1177/2150135117692778. No abstract available.




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Select item 28329452 13.


  1. Preliminary Experience With the Use of an Extracellular Matrix to Augment the Native Pulmonary Valve During Repair of Tetralogy of Fallot.

Dharmapuram A, Ramadoss N, Verma S, Gouthami V, Rao I.

World J Pediatr Congenit Heart Surg. 2017 Mar;8(2):174-181. doi: 10.1177/2150135116682450.




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Select item 28329450 15.