Congenital EP Featured Articles of May 2017

Congenital and Pediatric Cardiac EP Reviews of May 2017 Manuscripts

 

Ventricular pacing in single ventricles-A bad combination.

Bulic A, Zimmerman FJ, Ceresnak SR, Shetty I, Motonaga KS, Freter A, Trela AV, Hanisch D, Russo L, Avasarala K, Dubin AM.

Heart Rhythm. 2017 Jun;14(6):853-857. doi: 10.1016/j.hrthm.2017.03.035.

PMID: 28528723

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Take Home Points:

 

  • For single ventricle patients with ≥50% ventricular pacing, there was a high rate of moderate-to-severe ventricular systolic dysfunction (68%), AV valve regurgitation (55%), and death/transplantation (23%) in this study.
  • Compared to controls that were matched for age, similar ventricular morphology, and follow up duration, all 3 of the above endpoints were much more frequently observed in those with chronic ventricular pacing vs non-paced controls

 

J MooreCommentary by Dr. Jeremy Moore (Los Angeles) Congenital and Pediatric Cardiac EP section editor:  This was a single center study from 2 institutions over a 25-year period (1990 – 2015) that included patients with single ventricle congenital heart disease and ≥ 50% ventricular pacing. Cases with ventricular pacing were matched to a non-paced single ventricle control group in a 1:2 fashion for age, gender, single ventricle morphology, and similar follow-up duration.

The authors noted similar baseline characteristics between cases and controls, including similar degrees of ventricular systolic function and AV valve regurgitation before pacing. Ventricular morphology was also similar and was most commonly related to HLHS (40%), followed by DILV (24%), TA (13%), and DORV (12%). The pacing indication was divided nearly equally between postoperative AV block and nonsurgical advanced second or third-degree AV block.

The main study findings were that patients exposed to ventricular pacing fared far worse than their non-paced controls. Patients in the paced group were more likely to develop moderate-to-severe ventricular systolic dysfunction (68% vs 15%), moderate-to-severe AV valve regurgitation (55% vs 8%), were more often treated with heart failure medication (65% vs 21%), and experienced transplant/death (23% vs 6%) vs controls over a mean of 6.6 years.

May ep 1

 

Red, severe; yellow, moderate; green, mild; blue, no ventricular systolic dysfunction

The authors concluded that single ventricle patients requiring ventricular pacing are at a much higher risk for developing moderate-to-severe ventricular systolic dysfunction and AV valve regurgitation compared to those who are not paced. There was a 5-fold increased risk for death or heart transplantation. These risks appeared to be independent of baseline characteristics and attributable solely to chronic ventricular pacing.

 

Arrhythmia burden and related outcomes in Eisenmenger syndrome.

Baskar S, Horne P, Fitzsimmons S, Khoury PR, Vettukattill J, Miwa K, Awake T, Spence M, Sakazaki H, Veldtman G.

Congenit Heart Dis. 2017 May 19. doi: 10.1111/chd.12481. [Epub ahead of print]

PMID: 28523857

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Take Home Points:

 

  • AV valve regurgitation and prolonged QRS duration appear to be two important factors associated with arrhythmia in adult patients with Eisenmenger syndrome.
  • Arrhythmias occurred in 18% of Eisenmenger patients in this study, with the most common mechanisms being supraventricular tachycardia (57%), followed by NSVT (21%) and VT (21%).
  • The most important factor associated with sudden death by multivariate analysis in this study was prior therapy with antiarrhythmic drugs.

 

Commentary by Dr. Jeremy Moore (Los Angeles) Congenital and Pediatric Cardiac EP section editor:  This was a multicenter retrospective study of arrhythmias in adult Eisenmenger patients (≥ 18 years of age) at 2 centers in the U.K. and one in Japan. The authors were able to identify a total of 167 patients with Eisenmenger syndrome who had complete follow-up data. Clinical tachycardias were classified as NSVT, VT, or SVT (the latter further characterized as AF, AF/AFL, and paroxysmal SVT); whereas atrial and ventricular ectopy were excluded from the analysis. The authors looked at univariate and multivariate predictors of 3 major predefined outcomes that included 1) arrhythmia, 2) overall mortality, and 3) sudden death.

 

Arrhythmia occurrence was relatively common, being observed in 30 (18%) patients and were most frequently classified as SVT in 57%, followed by NSVT/VT in 42%. Predictors of arrhythmia included AV valve regurgitation, prolonged QRS duration, and absence of Downs syndrome.

May ep 2

 

Of the total cohort, 21 patients died and 8 patients died suddenly (3 with documented VF at the time of the arrest). Predictors of overall mortality included any history of arrhythmia, antiarrhythmic drug therapy, and higher NYHA class. Predictors of sudden death included documented arrhythmia and need for antiarrhythmic drug therapy. In the multivariate analysis, only antiarrhythmic drug therapy predicted sudden death.

May EP 3

 

 DTT = disease targeting therapy (i.e. advanced pulmonary hypertension therapy)

 

The authors concluded that arrhythmias in this group of ACHD patients are common, affecting approximately one-fifth of patients and that AV valve regurgitation and prolonged QRS duration were associated. Likewise, arrhythmias themselves were associated with all-cause mortality and sudden death.

 

These study findings are not novel, but do strengthen prior observations regarding risk for sudden death in the adult Eisenmenger population. The largest report evaluating this risk previously was the case-control study from the Netherlands in 2012 which included 33 cases of sudden death.* This prior study by Koyak and colleagues only reported bivariate associations, but found that heart failure symptoms (OR 2.7), heart failure medication (OR 3.), antiarrhythmic drug therapy (OR 3.4), QRS duration (1.34 per 10-ms increase), impaired systemic ventricular function (OR 8.2), impaired subpulmonary ventricular function (OR 5.0) and increased creatinine (OR 1.12 per 10 µMol increase) were all associated with sudden death. Clearly, more data on the risk for sudden death in this population is needed, but a relationship with prior arrhythmic event and especially antiarrhythmic drug therapy seems particularly important based on data from this smaller, but updated report.

 

*Koyak et al. Circulation 2012; 126(16):1944-1954

 

CHD EP May 2017

 

  1. Congenital heart block and immune mediated sensorineural hearing loss: possible cross reactivity of immune response.

Bason C, Pagnini I, Brucato A, Maestroni S, Puccetti A, Lunardi C, Cimaz R.

Lupus. 2017 Jul;26(8):835-840. doi: 10.1177/0961203316682099. Epub 2016 Dec 5.

PMID: 27913750

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  1. Sudden death in athletes.

Corrado D, Zorzi A.

Int J Cardiol. 2017 Jun 15;237:67-70. doi: 10.1016/j.ijcard.2017.03.034. Epub 2017 Mar 10.

PMID: 28318658

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  1. [Pulmonary revalvulation and rhythmologenic risks in patients with repaired tetralogy of Fallot].

Pilato R, Lacroix D, Domanski O, Godart F.

Presse Med. 2017 Jun 2. pii: S0755-4982(17)30112-4. doi: 10.1016/j.lpm.2017.02.006. [Epub ahead of print] French.

PMID: 28583744

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  1. Cardiac Arrhythmias in Adults with Congenital Heart Disease.

Balaji S, Mandapati R, Shivkumar K.

Card Electrophysiol Clin. 2017 Jun;9(2):xv-xvi. doi: 10.1016/j.ccep.2017.04.001. No abstract available.

PMID: 28457248

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  1. Arrhythmia Surgery for Adults with Congenital Heart Disease.

Deal BJ, Mavroudis C.

Card Electrophysiol Clin. 2017 Jun;9(2):329-340. doi: 10.1016/j.ccep.2017.02.014. Review.

PMID: 28457246

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  1. Cardiac Arrhythmias in Adults with Congenital Heart Disease: Pacemakers, Implantable Cardiac Defibrillators, and Cardiac Resynchronization Therapy Devices.

Cecchin F, Halpern DG.

Card Electrophysiol Clin. 2017 Jun;9(2):319-328. doi: 10.1016/j.ccep.2017.02.013. Epub 2017 Mar 31. Review.

PMID: 28457245

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  1. Drug Therapy in Adult Congenital Heart Disease.

Contractor T, Levin V, Mandapati R.

Card Electrophysiol Clin. 2017 Jun;9(2):295-309. doi: 10.1016/j.ccep.2017.02.011. Review.

PMID: 28457243

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  1. Sudden Cardiac Death in Adult Congenital Heart Disease.

Ávila P, Chaix MA, Mondésert B, Khairy P.

Card Electrophysiol Clin. 2017 Jun;9(2):225-234. doi: 10.1016/j.ccep.2017.02.003. Epub 2017 Mar 18. Review.

PMID: 28457237

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  1. Ventricular Arrhythmias in Adult Congenital Heart Disease: Mechanisms, Diagnosis, and Clinical Aspects.

Sathananthan G, Harris L, Nair K.

Card Electrophysiol Clin. 2017 Jun;9(2):213-223. doi: 10.1016/j.ccep.2017.02.004. Epub 2017 Mar 18. Review.

PMID: 28457236

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  1. Supraventricular Tachycardia in Adult Congenital Heart Disease: Mechanisms, Diagnosis, and Clinical Aspects.

Janson CM, Shah MJ.

Card Electrophysiol Clin. 2017 Jun;9(2):189-211. doi: 10.1016/j.ccep.2017.02.005. Review.

PMID: 28457235

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  1. Bradyarrhythmias in Congenital Heart Disease.

Carlson SK, Patel AR, Chang PM.

Card Electrophysiol Clin. 2017 Jun;9(2):177-187. doi: 10.1016/j.ccep.2017.02.002. Epub 2017 Mar 22. Review.

PMID: 28457234

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  1. Introduction to the Congenital Heart Defects: Anatomy of the Conduction System.

Moore JP, Aboulhosn JA.

Card Electrophysiol Clin. 2017 Jun;9(2):167-175. doi: 10.1016/j.ccep.2017.02.001. Epub 2017 Mar 14. Review.

PMID: 28457233

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  1. Ventricular pacing in single ventricles-A bad combination.

Bulic A, Zimmerman FJ, Ceresnak SR, Shetty I, Motonaga KS, Freter A, Trela AV, Hanisch D, Russo L, Avasarala K, Dubin AM.

Heart Rhythm. 2017 Jun;14(6):853-857. doi: 10.1016/j.hrthm.2017.03.035.

PMID: 28528723

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  1. Predictors of acute inefficacy and the radiofrequency energy time required for cavotricuspid isthmus-dependent atrial flutter ablation.

Pérez-Rodon J, Rodriguez-García J, Sarrias-Merce A, Rivas-Gandara N, Roca-Luque I, Francisco-Pascual J, Santos-Ortega A, Martín-Sánchez G, Ferreira-González I, Rodríguez-Palomares J, Evangelista-Masip A, García-Dorado D, Moya-Mitjans À.

J Interv Card Electrophysiol. 2017 Jun;49(1):83-91. doi: 10.1007/s10840-017-0232-z. Epub 2017 Mar 6.

PMID: 28265782

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  1. Lone Pediatric Atrial Fibrillation in the United States: Analysis of Over 1500 Cases.

El-Assaad I, Al-Kindi SG, Saarel EV, Aziz PF.

Pediatr Cardiol. 2017 Jun;38(5):1004-1009. doi: 10.1007/s00246-017-1608-7. Epub 2017 Apr 3.

PMID: 28374048

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  1. Permanent nonselective His bundle pacing in an adult with L-transposition of the great arteries and complete AV block.

Kean AC, Kay WA, Patel JK, Miller JM, Dandamudi G.

Pacing Clin Electrophysiol. 2017 May 24. doi: 10.1111/pace.13107. [Epub ahead of print]

PMID: 28543795

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  1. Analysis of adults with congenital heart disease presenting to pediatric emergency departments with arrhythmias.

Mohan S, Moffett BS, Lam W, de la Uz C, Miyake C, Valdes SO, Kim JJ.

Congenit Heart Dis. 2017 May 22. doi: 10.1111/chd.12478. [Epub ahead of print]

PMID: 28544787

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  1. Analysis of Screening Electrocardiogram for the Subcutaneous Defibrillator in Adults with Congenital Heart Disease.

Thomas VC, Peterson M, McDaniel M, Restrepo H, Rothman A, Jain A.

Pediatr Cardiol. 2017 May 22. doi: 10.1007/s00246-017-1635-4. [Epub ahead of print]

PMID: 28534239

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  1. Arrhythmia burden and related outcomes in Eisenmenger syndrome.

Baskar S, Horne P, Fitzsimmons S, Khoury PR, Vettukattill J, Niwa K, Agaki T, Spence M, Sakazaki H, Veldtman G.

Congenit Heart Dis. 2017 May 19. doi: 10.1111/chd.12481. [Epub ahead of print]

PMID: 28523857

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  1. Force-Sensing Catheters During Pediatric Radiofrequency Ablation: The FEDERATION Study.

Dalal AS, Nguyen HH, Bowman T, Van Hare GF, Avari Silva JN.

J Am Heart Assoc. 2017 May 17;6(5). pii: e005772. doi: 10.1161/JAHA.117.005772.

PMID: 28515113 Free Article

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  1. Hypoplastic Left Heart Syndrome with Congenital Complete Heart Block.

Al-Kubaisi M, Aly SA, Mohammad Nijres B, Awad S.

Pediatr Cardiol. 2017 May 17. doi: 10.1007/s00246-017-1631-8. [Epub ahead of print]

PMID: 28512719

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  1. Epicardial cardioverter-defibrillator implantation in a 4-month-old infant bridged to heart transplantation.

Carro C, Cereda AF, Annoni G, Marianeschi SM.

Interact Cardiovasc Thorac Surg. 2017 May 16. doi: 10.1093/icvts/ivx129. [Epub ahead of print]

PMID: 28510647

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  1. Conventional and right-sided screening for subcutaneous ICD in a population with congenital heart disease at high risk of sudden cardiac death.

Alonso P, Osca J, Rueda J, Cano O, Pimenta P, Andres A, Sancho MJ, Martinez L.

Ann Noninvasive Electrocardiol. 2017 May 15. doi: 10.1111/anec.12461. [Epub ahead of print]

PMID: 28508439

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  1. Complete heart block complicating the acute phase of respiratory syncytial virus bronchiolitis.

Karatza AA, Kiaffas M, Rammos S.

Pediatr Pulmonol. 2017 May 9. doi: 10.1002/ppul.23714. [Epub ahead of print]

PMID: 28486756

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  1. Utility of Post-Mortem Genetic Testing in Cases of Sudden Arrhythmic Death Syndrome.

Lahrouchi N, Raju H, Lodder EM, Papatheodorou E, Ware JS, Papadakis M, Tadros R, Cole D, Skinner JR, Crawford J, Love DR, Pua CJ, Soh BY, Bhalshankar JD, Govind R, Tfelt-Hansen J, Winkel BG, van der Werf C, Wijeyeratne YD, Mellor G, Till J, Cohen MC, Tome-Esteban M, Sharma S, Wilde AAM, Cook SA, Bezzina CR, Sheppard MN, Behr ER.

J Am Coll Cardiol. 2017 May 2;69(17):2134-2145. doi: 10.1016/j.jacc.2017.02.046.

PMID: 28449774 Free PMC Article

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  1. Outcomes of Direct Current Cardioversion in Adults With Congenital Heart Disease.

Egbe AC, Asirvatham SJ, Connolly HM, Kapa S, Desimone CV, Vaidya VR, Deshmukh AJ, Khan AR, McLeod CJ, Melduni RM, Ammash NM.

Am J Cardiol. 2017 May 1;119(9):1468-1472. doi: 10.1016/j.amjcard.2017.01.018. Epub 2017 Feb 9.

PMID: 28262200

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  1. Increased risk of thromboembolic events in adult congenital heart disease patients with atrial tachyarrhythmias.

Masuda K, Ishizu T, Niwa K, Takechi F, Tateno S, Horigome H, Aonuma K.

Int J Cardiol. 2017 May 1;234:69-75. doi: 10.1016/j.ijcard.2017.02.004. Epub 2017 Feb 5.

PMID: 28209388

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  1. Acute Cardiac MRI Assessment of Radiofrequency Ablation Lesions for Pediatric Ventricular Arrhythmia: Feasibility and Clinical Correlation.

Grant EK, Berul CI, Cross RR, Moak JP, Hamann KS, Sumihara K, Cronin I, O’Brien KJ, Ratnayaka K, Hansen MS, Kellman P, Olivieri LJ.

J Cardiovasc Electrophysiol. 2017 May;28(5):517-522. doi: 10.1111/jce.13197. Epub 2017 Mar 28.

PMID: 28245348

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  1. Repetitive ventricular tachycardia in a syncopal child: Cause or incidental finding ?

Massin M, Jacquemart C, Khaldi K.

Ann Noninvasive Electrocardiol. 2017 May 30. doi: 10.1111/anec.12472. [Epub ahead of print]

PMID: 28557290

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  1. Family Screening for Brugada Syndrome in Asymptomatic Young Patients. Is it Better not to Know?

Gonzalez Corcia MC, Brugada P.

Pediatr Cardiol. 2017 May 26. doi: 10.1007/s00246-017-1637-2. [Epub ahead of print] No abstract available.

PMID: 28550419

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Select item 28549058

 

  1. Permanent nonselective His bundle pacing in an adult with L-transposition of the great arteries and complete AV block.

Kean AC, Kay WA, Patel JK, Miller JM, Dandamudi G.

Pacing Clin Electrophysiol. 2017 May 24. doi: 10.1111/pace.13107. [Epub ahead of print]

PMID: 28543795

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Select item 28540398

 

  1. Analysis of adults with congenital heart disease presenting to pediatric emergency departments with arrhythmias.

Mohan S, Moffett BS, Lam W, de la Uz C, Miyake C, Valdes SO, Kim JJ.

Congenit Heart Dis. 2017 May 22. doi: 10.1111/chd.12478. [Epub ahead of print]

PMID: 28544787

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Select item 28531295

 

  1. The effects of gender on electrical therapies for the heart: physiology, epidemiology, and access to therapies: A report from the XII Congress of the Italian Association on Arrhythmology and Cardiostimulation (AIAC).

Boriani G, Lorenzetti S, Cerbai E, Oreto G, Bronzetti G, Malavasi VL, Biffi A, Padeletti L, Botto G, Diemberger I.

Europace. 2017 May 19. doi: 10.1093/europace/eux068. [Epub ahead of print]

PMID: 28525585

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  1. Cost of Unnecessary Testing in the Evaluation of Pediatric Syncope.

Redd C, Thomas C, Willis M, Amos M, Anderson J.

Pediatr Cardiol. 2017 May 18. doi: 10.1007/s00246-017-1625-6. [Epub ahead of print]

PMID: 28523341

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  1. Pacing Induced Ventricular Dysfunction in a Child: Improvement with Reduction in Paced Rate.

Garg S, Balaji S.

Pediatr Cardiol. 2017 May 17. doi: 10.1007/s00246-017-1629-2. [Epub ahead of print]

PMID: 28512720

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  1. Propranolol Versus Digoxin in the Neonate for Supraventricular Tachycardia (from the Pediatric Health Information System).

Bolin EH, Lang SM, Tang X, Collins RT.

Am J Cardiol. 2017 May 15;119(10):1605-1610. doi: 10.1016/j.amjcard.2017.02.017. Epub 2017 Mar 1.

PMID: 28363353

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  1. A Mutation in the G-Protein Gene GNB2 Causes Familial Sinus Node and Atrioventricular Conduction Dysfunction.

Stallmeyer B, Kuß J, Kotthoff S, Zumhagen S, Vowinkel K, Rinné S, Matschke LA, Friedrich C, Schulze-Bahr E, Rust S, Seebohm G, Decher N, Schulze-Bahr E.

Circ Res. 2017 May 12;120(10):e33-e44. doi: 10.1161/CIRCRESAHA.116.310112. Epub 2017 Feb 20.

PMID: 28219978

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  1. Efficacy of Flecainide in the Treatment of Catecholaminergic Polymorphic Ventricular Tachycardia: A Randomized Clinical Trial.

Kannankeril PJ, Moore JP, Cerrone M, Priori SG, Kertesz NJ, Ro PS, Batra AS, Kaufman ES, Fairbrother DL, Saarel EV, Etheridge SP, Kanter RJ, Carboni MP, Dzurik MV, Fountain D, Chen H, Ely EW, Roden DM, Knollmann BC.

JAMA Cardiol. 2017 May 10. doi: 10.1001/jamacardio.2017.1320. [Epub ahead of print]

PMID: 28492868

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  1. Successful catheter ablation of ventricular ectopy in a young patient with implanted Melody valve.

Jan M, Žižek D, Mazic U, Klemen L, Mijovski G, Peichl P.

Europace. 2017 May 4. doi: 10.1093/europace/eux033. [Epub ahead of print] No abstract available.

PMID: 28472281

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  1. Phase-contrast magnet resonance imaging reveals regional, transmural, and base-to-apex dispersion of mechanical dysfunction in patients with long QT syndrome.

Brado J, Dechant MJ, Menza M, Komancsek A, Lang CN, Bugger H, Foell D, Jung BA, Stiller B, Bode C, Odening KE.

Heart Rhythm. 2017 May 4. pii: S1547-5271(17)30578-7. doi: 10.1016/j.hrthm.2017.04.045. [Epub ahead of print]

PMID: 28479515

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  1. Efficacy of Intravenous Sotalol for Treatment of Incessant Tachyarrhythmias in Children.

Li X, Zhang Y, Liu H, Jiang H, Ge H, Zhang Y.

Am J Cardiol. 2017 May 1;119(9):1366-1370. doi: 10.1016/j.amjcard.2017.01.034. Epub 2017 Feb 10.

PMID: 28283175 Free Article

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  1. Intraoperative Three-Dimensional Mapping of Supraventricular Tachycardia in a Young Fontan Patient.

Perry JC, Williams MR, Shepard S, Bratincsak A, Murphy C, Murthy R, Ebrahim M, Lamberti JJ.

Ann Thorac Surg. 2017 May;103(5):e453-e456. doi: 10.1016/j.athoracsur.2016.10.069.

PMID: 28431725

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  1. Retrosternal Implantation of the Cardioverter-Defibrillator Lead in an Infant.

Hata H, Sumitomo N, Nakai T, Amano A.

Ann Thorac Surg. 2017 May;103(5):e449-e451. doi: 10.1016/j.athoracsur.2016.10.063.

PMID: 28431724

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Select item 28431723

 

  1. Wolff-Parkinson-White syndrome: a single exercise stress test might be misleading.

Salavitabar A, Silver ES, Liberman L.

Cardiol Young. 2017 May;27(4):804-807. doi: 10.1017/S1047951116002055. Epub 2016 Nov 21.

PMID: 27869041

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Select item 27839529

 

  1. A Toddler With Central Venous Catheter Develops Tachycardia.

Shapiro DR, Dudek CJ, Ho JG.

Clin Pediatr (Phila). 2017 May;56(5):496-499. doi: 10.1177/0009922816661331. Epub 2016 Jul 26. No abstract available.

PMID: 27466077

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Select item 28235145

 

  1. Junctional ectopic tachycardia in late period after early postoperative complete atrioventricular block: Messenger of return to normal sinus rhythm? : Explanation with four case series.

Ozyilmaz I, Ergul Y, Ozyilmaz S, Guzeltas A.

J Electrocardiol. 2017 May – Jun;50(3):378-382. doi: 10.1016/j.jelectrocard.2017.01.015. Epub 2017 Feb 1.

PMID: 28189280

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CHD Intervention Featured Articles of May 2017

Interventional Cardiology Reviews of May 2017 Manuscripts

 

Interventional Treatment of Patients with Congenital Heart Disease: Nationwide Danish Experience Over 39 Years.

Larsen SH, Olsen M, Emmertsen K, Hjortdal VE.

J Am Coll Cardiol. 2017 Jun 6;69(22):2725-2732. doi: 10.1016/j.jacc.2017.03.587.

PMID: 28571637

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Take Home Points:

 

  • Over the last 39 years, interventional (surgical or catheter based) treatment of congenital heart disease (CHD) is being performed on younger and more preterm patients.
  • There has been an increase in the percent of catheter-based interventions over time.
  • 10-year survival following interventions for CHD has increased however CHD, even simple lesions alone, is still associated with lower long-term survival than non-CHD controls.

 

Whiteside, WendyComment from Dr. Wendy Whiteside (Cincinnati), section editor of Congenital Heart Disease Interventions Journal Watch: The Danish National Registry of Patients is uniquely positioned to provide extensive longitudinal population-based health data. In this article, Larsen et al make use of this database to bring meaningful numbers in support of what we all know to be true—the exciting progression of interventional therapies for CHD over the last nearly 40 years.

 

From the database, Larsen et al analyzed all children (<18 years of age) treated with congenital heart surgery or catheter-based interventions (beginning in 1990 for catheter procedures) for CHD in Denmark from 1977 through 2015. Dates were divided into 3 periods (1977-1989; 1990-1999, and 2003-2015) to allow for comparison across time periods. The study population represented 3.9% of the live births in Denmark.  Over the three time periods, median age at first procedure decreased (median 3.4 to 0.8 to 0.6 years in the 3 periods, respectively), and the percentage of preterm patients increased (median 6.7 to 14.3 to 18.5% of the population) suggesting interventions being performed in younger and smaller patients over time in parallel with advances in surgical techniques and improved neonatal care.  While there was an increase in the percent of the cohort treated for CHD from periods 1 to 2 (26.7% vs 37.4%) there was not a continued increase in period 3 and there were fewer interventions for complex lesions, which may reflect introduction of second trimester screening for CHD in period 3 and more frequent terminations of pregnancy for severe CHD.  In addition, the distribution of surgical to catheter-based interventions has evolved over time with an increase in catheter based procedures (0 to 5.8 to 25.9% of procedures, in the 3 periods), and more patients undergoing no surgery at all (0% in period 1, 4.8% in period 2, 24% in period 3).

 

Thirty-day survival increased across periods from 97% to 98% to 100% in period 3, with 10-year survival also increasing (from 80% to 87% to 93%).  Despite this improvement over time, both simple and complex CHD are associated with lower survival compared with the age and sex matched control population, though with the difference between the CHD and control populations decreasing over time.

 

While the depth of this dataset is impressive, there are some limitations to generalization of these data that should be considered when utilizing these data in the US.  In Denmark, there has been centralization of cardiothoracic surgery care to 2 hospitals, which may impact overall outcomes and survival.  In addition, frequent termination of pregnancy in the setting of a fetus with severe CHD, impacts the complexity of patients being born and requiring subsequent interventions, and may therefore limit generalizability in the US where this practice differs.

 

Initial clinical experience with the Medtronic Micro Vascular Plug™ in transcatheter occlusion of PDAs in extremely premature infants.

Sathanandam S, Justino H, Waller BR 3rd, Radtke W, Qureshi AM.

Catheter Cardiovasc Interv. 2017 May;89(6):1051-1058. doi: 10.1002/ccd.26878. Epub 2016 Nov 26.

PMID: 27888552

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Take Home Points:

 

  • The Medtronic Micro Vascular Plug (MVP) provides a low profile, flexible, and “diskless” device that may be well suited for closure of the long tubular PDA seen in small, extremely premature infants.
  • Procedural success with the MVP for ductal closure was 93% with no complications seen, no device impingement on the LPA or aorta, and only 1 small residual shunt (resolved in follow-up).
  • Minimal diameter to unconstrained device diameter was ~1:2, with the MVP-5Q device being the most commonly used device size.

 

Comment from Dr. Wendy Whiteside (Cincinnati), section editor of Congenital Heart Disease Interventions Journal Watch: Santhanandam et al, report their two-center experience with the use of the Medtronic Micro Vascular Plug (MVP) specifically for closure of PDAs in extremely premature infants.  While the experience remains small (15 total patients) this paper provides technical detail and procedural tips for individuals seeking to utilize this device in their practice.

 

Transcatheter PDA occlusion may provide benefit over surgical ligation in the extremely premature infants by offering less disruption of respiratory mechanics and post-procedure escalation of respiratory support.  Previously, our ability to provide Transcatheter closure for these patients has been limited by the availability of an appropriately sized device (both in actual device length and diameter as well as device delivery profile) to accommodate the small vasculature and tight intracardiac relations in these small patients. The MVP, used mostly in adult neuroradiology and interventional radiology procedures, meets many of these requirements—it is low profile (deliverable through a microcatheter), delivered on an 0.018 nitinol pusher wire that is flexible and may allow for less device distortion on the delivery system, and has a diskless design with an uncovered distal (aortic) end, allowing for some flexibility in positioning of the aortic end without causing aortic obstruction.

 

Of the 15 patients, the MVP was used in 2 patients in whom the “more traditional” AVP-II device was unable to be placed due to LPA stenosis by the device.  One patient had a short, vertically oriented ductus that would not accommodate the length of the MVP (1 procedural failure, 93% success rate).  Median weight at the time of the procedure was 1210 grams (range 700-3500 grams). The ratio of the minimal PDA diameter to the unconstrained device diameter was ~1:2, with the MVP-5Q device chosen in all but 3 patients.  Technically, arterial access was not obtained in patients <2 kg, so the entirety of the procedure, including angiographic imaging of the ductus, was performed successfully antegrade through the PDA, and device positioning augmented by use of intraprocedural transthoracic echo guidance.    There were no procedural complications.  One patient had a small residual shunt after device placement (resolved on follow-up) thought to be secondary to disruption of the PFTE membrane due to multiple resheathings of the device.  Procedural times, fluoroscopy times, and contrast doses were all favorable.  The MVP provides a promising device for the transcatheter occlusion of PDA in extremely premature infants, and allows us to keep pushing the lower limit of patient weight for successful transcatheter occlusion.  Ongoing experience with this device across more operators and in more ductal anatomies will be necessary.

 

Catheter Cardiovasc Interv. 2017 May 4. doi: 10.1002/ccd.27115. [Epub ahead of print]

Stenting of the ascending aorta revisited.

Moiduddin NJ1,2Rios R1El-Said H1Moore JW1.

10.1002/ccd.27115. [Epub ahead of print]

PMID: 28471087

 

Take Home Points:

 

  • Transcatheter ascending aortic interventions have been avoided in the past due to potential damage to the aortic valve leaflets or coronary ostia
  • With improved imaging modalities, such as 3D rotational angiography, more accurate anatomic assessments can be made to guide transcatheter interventions
  • Adding transcatheter ascending aortic interventions for patients with acquired post-operative ascending aortic intervention can be a safe alternative to help avoid additional cardiac surgeries for this patient population

 

Seckler, MikeCommentary from Dr. Michael Seckeler (Tucson), section editor of Congenital Heart Disease Interventions Journal Watch:   Transcatheter intervention on ascending aortic narrowing has been somewhat controversial, particularly because of potential damage to the aortic valve leaflets and coronary ostia. The authors present a series of three successful ascending aortic interventions in patients with acquired aortic narrowing. All were post-operative from various congenital heart defect interventions and the narrowings were far enough distal from the aortic valve leaflets to allow for safe stent placement.

The authors emphasize the importance of 3D rotational angiography to help accurately measure both the greater and lesser curvatures of the ascending aorta and using a long sheath larger than needed to allow for hand injections to accurately guide stent positioning. They also acknowledge the risk of recoil after angioplasty alone and aortic wall injury or disruption, so advocate for primary stent placement to minimize this risk with covered stents available in the case of injury.

 

Transcatheter Retrieval of Cardiovascular Foreign Bodies in Children: A 15-Year Single Centre Experience.

Kudumula V, Stumper O, Noonan P, Mehta C, De Giovanni J, Stickley J, Dhillon R, Bhole V.

Pediatr Cardiol. 2017 May 24. doi: 10.1007/s00246-017-1639-0. [Epub ahead of print]

PMID:  28540398

Similar articles

 

Take Home Points:

 

  • As interventional congenital catheterization procedures increase in complexity, the chance for embolized devices has also increased
  • Transcatheter retrieval of embolized devices and other foreign bodies has been utilized for over 50 years, but there are limited data for pediatric patients
  • The authors present a 15-year review with a 90% success rate for retrieval of a variety of embolized devices and catheter fragments with minimal adverse events
  • Despite the high success rate, the authors emphasize the importance of careful planning and surgical backup

 

Commentary from Dr. Michael Seckeler (Tucson), section editor of Congenital Heart Disease Interventions Journal Watch:   As interventional congenital cardiology has evolved, there is an increased risk for embolized devices. In addition, patients with chronic medical conditions frequently require long term central venous access and these catheters can become damaged with fragments embolizing. Both situations can frequently be treated by transcatheter retrieval techniques, which has yet to be studied in the pediatric population. The authors present a 15-year review of their single center experience.

 

During the study period, 62% of the 8956 catheterizations were interventional, with 78 (1.4%) involving retrieval of embolized foreign bodies. Mean patient age and weight were 4 years and 15 kg. The majority of foreign bodies (78%) were embolized devices and central venous catheter fragments. Of the embolized devices and stents, 96% were identified either during the initial catheterization or within the first 48 hours after implantation.

 

Embolization rates for common procedures were:

PDA devices/coils – 3%

ASD devices – 1.9%

VSD devices – 2.8%

Stents – 1.7%

Overall success rate for foreign body retrieval was 90%, with the highest individual success for PDA devices/coils. Retrieval was successful from both venous and arterial approaches with a variety of sheath sizes. The best results were reported with gooseneck snares. Importantly, devices that embolized to the left ventricle were not approached from a transcatheter route because of the risk to mitral valve chordae. There were minimal adverse events, with 5 patients with transient pulse loss and 2 requiring blood transfusion. Not surprisingly, complications were more common in younger, smaller patients. Also, the authors stress the importance of having surgical backup available, as transcatheter foreign body retrieval can be risky to the patient and is not always possible depending on the patient anatomy and location of embolized material.

 

 

CHD Interventions May 2017

 

  1. Comparison of self-expandable and balloon-expanding stents for hybrid ductal stenting in hypoplastic left heart complex.

Goreczny S, Qureshi SA, Rosenthal E, Krasemann T, Nassar MS, Anderson DR, Morgan GJ.

Cardiol Young. 2017 Jul;27(5):837-845. doi: 10.1017/S1047951116001347.

PMID: 28555538

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  1. Interventional Treatment of Patients With Congenital Heart Disease: Nationwide Danish Experience Over 39 Years.

Larsen SH, Olsen M, Emmertsen K, Hjortdal VE.

J Am Coll Cardiol. 2017 Jun 6;69(22):2725-2732. doi: 10.1016/j.jacc.2017.03.587.

PMID: 28571637

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  1. Simultaneous transcatheter therapy for perimembranous ventricular septal defect combined with patent ductus arteriosus.

Wang Q, Zhu X, Duanzhen Z, Zhang P, Chen H, Han X, Sheng X, Meng L.

J Card Surg. 2017 Jun;32(6):370-375. doi: 10.1111/jocs.13138. Epub 2017 May 11.

PMID: 28497553

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  1. Percutaneous management of failed bioprosthetic pulmonary valves in patients with congenital heart defects.

Tarzia P, Conforti E, Giamberti A, Varrica A, Giugno L, Micheletti A, Negura D, Piazza L, Saracino A, Carminati M, Chessa M.

J Cardiovasc Med (Hagerstown). 2017 Jun;18(6):430-435. doi: 10.2459/JCM.0000000000000486.

PMID: 27828833

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  1. Short-term cardiopulmonary efficiency improvement after transcatheter baffle leak closure in a Mustard-operated patient.

Mezzani A, Butera G, Chessa M, Micheletti A, Negura D, Calaciura R, Carminati M.

J Cardiovasc Med (Hagerstown). 2017 Jun;18(6):447-449. doi: 10.2459/JCM.0b013e32835dbbde. No abstract available.

PMID: 23314595

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  1. Coronary Sinus Defect Following Transcatheter Closure of ASD Using Amplatzer Septal Occluder: Potential Erosion by the Device.

Mohammad Nijres B, Al-Kubaisi M, Bokowski J, Abdulla RI, Awad S.

Pediatr Cardiol. 2017 Jun;38(5):1084-1086. doi: 10.1007/s00246-017-1613-x. Epub 2017 Apr 10.

PMID: 28396933

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  1. RV to PA conduits: impact of transcatheter pulmonary valve replacement in adults – a national register study.

Skoglund K, Svensson G, Thilén U, Dellborg M, Eriksson P.

Scand Cardiovasc J. 2017 Jun;51(3):153-158. doi: 10.1080/14017431.2017.1291988. Epub 2017 Feb 15.

PMID: 28276717

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  1. Perceptions of transcatheter device closure of patent ductus arteriosus in veterinary cardiology and evaluation of a canine model to simulate device placement: a preliminary study.

Saunders AB, Keefe L, Birch SA, Wierzbicki MA, Maitland DJ.

J Vet Cardiol. 2017 May 30. pii: S1760-2734(17)30026-7. doi: 10.1016/j.jvc.2017.04.002. [Epub ahead of print]

PMID: 28576477

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  1. Real-time 3D transesophageal echocardiography-guided closure of a complicated patent ductus arteriosus in a dog.

Doocy KR, Nelson DA, Saunders AB.

J Vet Cardiol. 2017 May 29. pii: S1760-2734(17)30036-X. doi: 10.1016/j.jvc.2017.04.001. [Epub ahead of print]

PMID: 28571753

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  1. Novel Three-Dimensional Image Fusion Software to Facilitate Guidance of Complex Cardiac Catheterization : 3D image fusion for interventions in CHD.

Goreczny S, Dryzek P, Morgan GJ, Lukaszewski M, Moll JA, Moszura T.

Pediatr Cardiol. 2017 May 27. doi: 10.1007/s00246-017-1627-4. [Epub ahead of print]

PMID: 28551818

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  1. Transcatheter Retrieval of Cardiovascular Foreign Bodies in Children: A 15-Year Single Centre Experience.

Kudumula V, Stumper O, Noonan P, Mehta C, De Giovanni J, Stickley J, Dhillon R, Bhole V.

Pediatr Cardiol. 2017 May 24. doi: 10.1007/s00246-017-1639-0. [Epub ahead of print]

PMID: 28540398

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  1. Embolic Foreign Material in the Central Nervous System of Pediatric Autopsy Patients With Instrumented Heart Disease.

Torre M, Lechpammer M, Paulson V, Prabhu S, Marshall AC, Juraszek AL, Padera RF, Bundock EA, Vargas SO, Folkerth RD.

J Neuropathol Exp Neurol. 2017 May 19. doi: 10.1093/jnen/nlx037. [Epub ahead of print]

PMID: 28525615

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  1. Radiation Safety in Children with Congenital and Acquired Heart Disease: A Scientific Position Statement on Multimodality Dose Optimization from the Image Gently Alliance.

Hill KD, Frush DP, Han BK, Abbott BG, Armstrong AK, DeKemp RA, Glatz AC, Greenberg SB, Herbert AS, Justino H, Mah D, Mahesh M, Rigsby CK, Slesnick TC, Strauss KJ, Trattner S, Viswanathan MN, Einstein AJ; Image Gently Alliance.

JACC Cardiovasc Imaging. 2017 May 17. pii: S1936-878X(17)30381-9. doi: 10.1016/j.jcmg.2017.04.003. [Epub ahead of print] Review.

PMID: 28514670 Free Article

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Select item 28512719

 

  1. Intergenerational differences in the effects of transcatheter closure of atrial septal defects on cardiac function.

Tashiro H, Suda K, Iemura M, Teramachi Y.

J Cardiol. 2017 May 13. pii: S0914-5087(17)30112-0. doi: 10.1016/j.jjcc.2017.03.014. [Epub ahead of print]

PMID: 28511801

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  1. Transcatheter interventions in adults with congenital heart disease: Surveys from the Society for Cardiovascular Angiography and Interventions to identify current patterns of care and perception on training requirements.

Wadia SK, Accavitti MJ Jr, Morgan GJ, Kenny D, Hijazi ZM, Jones TK, Cabalka AK, McElhinney DB, Kavinsky CJ.

Catheter Cardiovasc Interv. 2017 May 11. doi: 10.1002/ccd.27151. [Epub ahead of print]

PMID: 28493591

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  1. Real-time MRI guidance of cardiac interventions.

Campbell-Washburn AE, Tavallaei MA, Pop M, Grant EK, Chubb H, Rhode K, Wright GA.

J Magn Reson Imaging. 2017 May 11. doi: 10.1002/jmri.25749. [Epub ahead of print]

PMID: 28493526

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  1. Stenting of the ascending aorta revisited.

Moiduddin NJ, Rios R, El-Said H, Moore JW.

Catheter Cardiovasc Interv. 2017 May 4. doi: 10.1002/ccd.27115. [Epub ahead of print]

PMID: 28471087

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Select item 28471080

 

  1. Twenty years of experience with intraoperative pulmonary artery stenting.

Zampi JD, Loccoh E, Armstrong AK, Yu S, Lowery R, Rocchini AP, Hirsch-Romano JC.

Catheter Cardiovasc Interv. 2017 May 4. doi: 10.1002/ccd.27094. [Epub ahead of print]

PMID: 28471080

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  1. Modified transjugular approach for percutaneous atrial septal defect closure.

Bhargava RA, Phatarpekar A, Lanjewar CP, Kerkar PG.

Ann Pediatr Cardiol. 2017 May-Aug;10(2):197-199. doi: 10.4103/apc.APC_167_16.

PMID: 28566830 Free PMC Article

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  1. Pitfalls of stenting coarctation of an angulated right circumflex aortic arch in Goldenhar syndrome.

Rad EM, Mortezaeian H, Pouraliakbar HR, Hijazi ZM.

Ann Pediatr Cardiol. 2017 May-Aug;10(2):194-196. doi: 10.4103/apc.APC_134_16.

PMID: 28566829 Free PMC Article

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  1. Catheter hemodynamic assessment of the univentricular circulation.

Stumper O, Penford G.

Ann Pediatr Cardiol. 2017 May-Aug;10(2):167-174. doi: 10.4103/apc.APC_160_16. Review.

PMID: 28566825 Free PMC Article

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  1. Transcatheter closure of large atrial septal defects using 40 mm amplatzer septal occluder: Single group experience with short and intermediate term follow-up.

Dalvi B, Sheth K, Jain S, Pinto R.

Catheter Cardiovasc Interv. 2017 May;89(6):1035-1043. doi: 10.1002/ccd.26858. Epub 2016 Nov 12.

PMID: 27862916

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  1. Single-center experience in percutaneous closure of arterial duct with Amplatzer duct Occluder II additional sizes.

Mahmoud HT, Santoro G, Gaio G, D’Aiello FA, Capogrosso C, Palladino MT, Russo MG.

Catheter Cardiovasc Interv. 2017 May;89(6):1045-1050. doi: 10.1002/ccd.26860. Epub 2016 Nov 10.

PMID: 27862909

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  1. Novel use of the medtronic micro vascular plug for PDA closure in preterm infants.

Wang-Giuffre EW, Breinholt JP.

Catheter Cardiovasc Interv. 2017 May;89(6):1059-1065. doi: 10.1002/ccd.26855. Epub 2016 Nov 10.

PMID: 27860173

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  1. Transcatheter closure of large patent ductus arteriosus using custom made devices.

Rohit MK, Gupta A.

Catheter Cardiovasc Interv. 2017 May;89(6):E194-E199. doi: 10.1002/ccd.25349. Epub 2014 Jan 7.

PMID: 24323820

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  1. Acute and long-term effects of endovascular debanding of pulmonary arteries in a swine model.

Perez M, Kumar TS, Hoskoppal D, Akkhawattanangkul Y, Allen K, Knott-Craig CJ, Waller BR, Sathanandam S.

Congenit Heart Dis. 2017 May;12(3):340-349. doi: 10.1111/chd.12449.

PMID: 28580610

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  1. Transcatheter closure of calcified patent ductus arteriosus in older adult patients: Immediate and 12-month follow-up results.

Gu X, Zhang Q, Sun H, Fei J, Zhang X, Kutryk MJ.

Congenit Heart Dis. 2017 May;12(3):289-293. doi: 10.1111/chd.12437. Epub 2016 Nov 22.

PMID: 27874259

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  1. Dehiscence of a pulmonary bioprosthesis with a focal dissection of the pulmonary artery in a patient with congenital pulmonic stenosis.

Yucel E, Bhatt A, Mihos CG, Ghoshhajra BB, DeFaria Yeh D.

Echocardiography. 2017 May;34(5):776-778. doi: 10.1111/echo.13502. Epub 2017 Mar 27.

PMID: 28345243

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  1. Neurodevelopmental Outcome in Children after Fetal Cardiac Intervention for Aortic Stenosis with Evolving Hypoplastic Left Heart Syndrome.

Laraja K, Sadhwani A, Tworetzky W, Marshall AC, Gauvreau K, Freud L, Hass C, Dunbar-Masterson C, Ware J, Lafranchi T, Wilkins-Haug L, Newburger JW.

J Pediatr. 2017 May;184:130-136.e4. doi: 10.1016/j.jpeds.2017.01.034. Epub 2017 Feb 21.

PMID: 28233547

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  1. [Interventional cardiac catheterization in congenital heart disease].

Godart F, Houeijeh A.

Presse Med. 2017 May;46(5):497-508. doi: 10.1016/j.lpm.2016.11.013. Epub 2016 Dec 27. French.

PMID: 28038838

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  1. Utility and Clinical Profile of Dexmedetomidine in Pediatric Cardiac Catheterization Procedures: A Matched Controlled Analysis.

Riveros R, Makarova N, Riveros-Perez E, Chodavarapu P, Saasouh W, Yılmaz HO, Cuko E, Babazade R, Kimatian S, Turan A.

Semin Cardiothorac Vasc Anesth. 2017 May 1:1089253217708035. doi: 10.1177/1089253217708035. [Epub ahead of print]

PMID: 28549395

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  1. Exercise Capacity Before and After Stent Placement for Coarctation of the Aorta: A Single-Center Case Series.

Morrical BD, Anderson JH, Taggart NW.

Pediatr Cardiol. 2017 May 18. doi: 10.1007/s00246-017-1628-3. [Epub ahead of print]

PMID: 28523342

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  1. Transcatheter correction of Scimitar syndrome: occlusion of abnormal pulmonary venous drainage and vascular supply in an infant.

Saltik L, Ugan Atik S, Bornaun H.

Cardiol Young. 2017 May 16:1-3. doi: 10.1017/S1047951117000750. [Epub ahead of print]

PMID: 28506323

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  1. Transcatheter closure of a membranous ventricular septal defect in a 1.8-kg infant using Amplatzer Duct Occluder II additional size device.

Champaneri B, Kappanayil M, Kumar RK.

Cardiol Young. 2017 May 16:1-4. doi: 10.1017/S1047951117000695. [Epub ahead of print]

PMID: 28506322

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  1. Intergenerational differences in the effects of transcatheter closure of atrial septal defects on cardiac function.

Tashiro H, Suda K, Iemura M, Teramachi Y.

J Cardiol. 2017 May 13. pii: S0914-5087(17)30112-0. doi: 10.1016/j.jjcc.2017.03.014. [Epub ahead of print]

PMID: 28511801

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  1. Transcatheter interventions in adults with congenital heart disease: Surveys from the Society for Cardiovascular Angiography and Interventions to identify current patterns of care and perception on training requirements.

Wadia SK, Accavitti MJ Jr, Morgan GJ, Kenny D, Hijazi ZM, Jones TK, Cabalka AK, McElhinney DB, Kavinsky CJ.

Catheter Cardiovasc Interv. 2017 May 11. doi: 10.1002/ccd.27151. [Epub ahead of print]

PMID: 28493591

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  1. Long-term outcome after percutaneous closure of persistent left superior caval vein draining into the left atrium: a contrast-enhanced CT study.

Marini D, Castagno M, Millesimo M, Ferroni F, Ferraro G, Pace Napoleone C, Agnoletti G.

Cardiol Young. 2017 May 8:1-7. doi: 10.1017/S1047951117000737. [Epub ahead of print]

PMID: 28478769

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  1. Transcatheter closure of hemodynamic significant patent ductus arteriosus in 32 premature infants by amplatzer ductal occluder additional size-ADOIIAS.

Morville P, Akhavi A.

Catheter Cardiovasc Interv. 2017 May 4. doi: 10.1002/ccd.27091. [Epub ahead of print]

PMID: 28471089

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  1. Access to the native atria following conduit total cavopulmonary anastomosis.

Petersen RL, Danon S, Jureidini S.

Catheter Cardiovasc Interv. 2017 May 4. doi: 10.1002/ccd.27044. [Epub ahead of print]

PMID: 28470999

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  1. Transcatheter closure of the patent foramen ovale in children: intermediate-term follow-up results.

Sel K, Aykan HH, Duman D, Aypar E, Özkutlu S, Alehan D, Karagöz T.

Cardiol Young. 2017 May 2:1-5. doi: 10.1017/S1047951117000725. [Epub ahead of print]

PMID: 28460651

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  1. Cost-effectiveness analysis of different devices used for the closure of small-to-medium-sized patent ductus arteriosus in pediatric patients.

El-Saiedi SA, El Sisi AM, Mandour RS, Abdel-Aziz DM, Attia WA.

Ann Pediatr Cardiol. 2017 May-Aug;10(2):144-151. doi: 10.4103/0974-2069.205138.

PMID: 28566822 Free PMC Article

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  1. A roadmap for the aspiring interventional pediatric cardiologist.

Kumar RK.

Ann Pediatr Cardiol. 2017 May-Aug;10(2):109-113. doi: 10.4103/apc.APC_52_17. No abstract available.

PMID: 28566816 Free PMC Article

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  1. Percutaneous closure of an aortopulmonary window using Amplatzer Duct Occluder II: Additional Sizes: the first reported case.

Fiszer R, Zbroński K, Szkutnik M.

Cardiol Young. 2017 May;27(4):812-815. doi: 10.1017/S1047951116002134. Epub 2016 Nov 21.

PMID: 27869054

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  1. Transcatheter closure of patent ductus arteriosus using the AMPLATZER™ duct occluder II (ADO II).

Gruenstein DH, Ebeid M, Radtke W, Moore P, Holzer R, Justino H.

Catheter Cardiovasc Interv. 2017 May;89(6):1118-1128. doi: 10.1002/ccd.26968. Epub 2017 Mar 4.

PMID: 28258658

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  1. Initial clinical experience with the Medtronic Micro Vascular Plug™ in transcatheter occlusion of PDAs in extremely premature infants.

Sathanandam S, Justino H, Waller BR 3rd, Radtke W, Qureshi AM.

Catheter Cardiovasc Interv. 2017 May;89(6):1051-1058. doi: 10.1002/ccd.26878. Epub 2016 Nov 26.

PMID: 27888552

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  1. Single-center experience in percutaneous closure of arterial duct with Amplatzer duct Occluder II additional sizes.

Mahmoud HT, Santoro G, Gaio G, D’Aiello FA, Capogrosso C, Palladino MT, Russo MG.

Catheter Cardiovasc Interv. 2017 May;89(6):1045-1050. doi: 10.1002/ccd.26860. Epub 2016 Nov 10.

PMID: 27862909

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Select item 27860173

 

  1. Novel use of the medtronic micro vascular plug for PDA closure in preterm infants.

Wang-Giuffre EW, Breinholt JP.

Catheter Cardiovasc Interv. 2017 May;89(6):1059-1065. doi: 10.1002/ccd.26855. Epub 2016 Nov 10.

PMID: 27860173

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  1. Transcatheter Occlusion of a Giant Pulmonary Arteriovenous Malformation in a 1-year-old Child Using Amplatzer Vascular Plugs and Interlocking Detachable Coils.

Lim YJ.

Chonnam Med J. 2017 May;53(2):171-172. doi: 10.4068/cmj.2017.53.2.171. Epub 2017 May 25. No abstract available.

PMID: 28584799 Free Article

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  1. Outcomes After Decompression of the Right Ventricle in Infants With Pulmonary Atresia With Intact Ventricular Septum Are Associated With Degree of Tricuspid Regurgitation: Results From the Congenital Catheterization Research Collaborative.

Petit CJ, Glatz AC, Qureshi AM, Sachdeva R, Maskatia SA, Justino H, Goldberg DJ, Mozumdar N, Whiteside W, Rogers LS, Nicholson GT, McCracken C, Kelleman M, Goldstein BH.

Circ Cardiovasc Interv. 2017 May;10(5). pii: e004428. doi: 10.1161/CIRCINTERVENTIONS.116.004428.

PMID: 28500137

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CHD Surgery Featured Articles of May 2017

Congenital Heart Surgery Reviews of May 2017 Manuscripts

Functional Status and Quality of Life in Survivors of Extracorporeal Membrane Oxygenation After the Norwood Operation.

Friedland-Little JM, Uzark K, Yu S, Lowery R, Aicardi R, Hirsch-Romano JC.

Ann Thorac Surg. 2017 Jun;103(6):1950-1955. doi: 10.1016/j.athoracsur.2016.11.015. Epub 2017 Feb 21.

PMID: 28223051

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Take Home Points:

 

  • Survivors after ECMO support following a Norwood procedure demonstrate similar functional and quality of life outcomes as Norwood patients who do not require ECMO support.
  • Patients with single ventricle physiology demonstrate lower scores in these categories when compared to normal populations.

 

 

jeremy-herrmannCommentary from Dr. Jeremy Herrmann (Indianapolis), section editor of Congenital Heart Surgery Journal Watch:  While it is well understood that neonates who require ECMO support after a Norwood procedure have overall worse outcomes than those who did not, what is less well understood is how survivors after ECMO support fare in the intermediate term. The authors now offer insight into the functional performance of these patients. Using a previous prospectively collected patient cohort followed up to 7-8 years, they compared surviving patients who required ECMO support after the Norwood proceed with age-matched control patients who underwent a Norwood procedure without ECMO support. Validated inventories were used to assess functional status and quality of life. Interestingly, of all the items used to compare the ECMO and non-ECMO patients, the only difference was a lower perceived physical appearance score in the ECMO group. Consistent with other previous reports, both groups scored lower in functional status and quality than a healthy population. The authors conclude that patients who require ECMO support after a Norwood procedure and survive fare as well as those who do not require ECMO support in terms of functional status and quality of life. While the sample sizes of the present study are small, these findings may facilitate patient family counseling and provide a foundation for larger, longer-term studies evaluating these important outcomes in a very challenging patient population.

Variation in extubation failure rates after neonatal congenital heart surgery across Pediatric Cardiac Critical Care Consortium hospitals.

Benneyworth BD, Mastropietro CW, Graham EM, Klugman D, Costello JM, Zhang W, Gaies M.

J Thorac Cardiovasc Surg. 2017 Jun;153(6):1519-1526. doi: 10.1016/j.jtcvs.2016.12.042. Epub 2017 Feb 4.

PMID: 28259455

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Take Home Points:

 

  • Extubation failure occurs in 11% of neonates recovering from cardiac surgery
  • Airway anomalies are an independent risk factor for extubation failure
  • Wide variation in extubation failure rates exists across cardiac ICUs

 

 

Commentary from Dr. Jeremy Herrmann (Indianapolis), section editor of Congenital Heart Surgery Journal Watch:  This study is one of the latest to arise from the Pediatric Critical Care Consortium (PC4) database which is comprised of 14 centers that voluntarily submit clinical registry data for cardiac patients cared for in a cardiac ICU. The authors examined extubation failure (reintubation within 72 hours of first planned extubation) for 899 neonates who underwent cardiac surgical procedures. Extubation failure occurred in 11% of all cases. An extensive list of patient-related and perioperative variables was examined. Multivariable analysis revealed only the presence of an airway disorder to be associated with extubation failure even when failure occurred early (<24 hours) or later (24-72 hours). Patients who suffered early extubation failure were more likely to have longer ICU and hospital lengths of stay as well as higher in-hospital mortality. Additionally, there was a wide range of extubation failure rates across centers with two centers registering significantly higher than the average rate (5-22%; Figure 1). The authors reason that this method of cross-institutional reporting may facilitate adoption or transference of best-practices, especially when outliers are identified. The major limitations of this study are the typical limitations of any database-centered project, though the careful entry and validation of data in the PC4 database are certainly strengths of the program. It will be interesting to observe what additional practice pattern variations are identified through PC4 as the program continues to accrue more programs and enrolled patients.

May surgery 1

 

CHD Surgery May 2017

 

  1. Early postoperative extubation of unstable patients following total cavopulmonary connection: impact on circulation and outcome.

Georgiev S, Balling G, Ruf B, Ackermann K, von Ohain JP, Schreiber C, Ewert P.

Cardiol Young. 2017 Jul;27(5):860-869. doi: 10.1017/S1047951116001402. Epub 2016 Oct 18.

PMID: 27751196

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  1. Oncotic pressure and paediatric cardiopulmonary bypass: establishing baseline data for complex congenital cardiac surgery and its relation to risk stratification.

Crook R, Issitt R.

Perfusion. 2017 Jul;32(5):378-382. doi: 10.1177/0267659117690251. Epub 2017 Jan 23.

PMID: 28110616

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  1. Improvement in perioperative care in pediatric cardiac surgery by shifting the primary focus of treatment from cardiac output to perfusion pressure: Are beta stimulants still needed?

Hosseinpour AR, van Steenberghe M, Bernath MA, Di Bernardo S, Pérez MH, Longchamp D, Dolci M, Boegli Y, Sekarski N, Orrit J, Hurni M, Prêtre R, Cotting J.

Congenit Heart Dis. 2017 Jun 5. doi: 10.1111/chd.12485. [Epub ahead of print]

PMID: 28580658

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  1. Mechanical Concepts Applied in Congenital Heart Disease and Cardiac Surgery.

Gerrah R, Haller SJ, George I.

Ann Thorac Surg. 2017 Jun;103(6):2005-2014. doi: 10.1016/j.athoracsur.2017.01.068. Epub 2017 Apr 28. Review.

PMID: 28457478

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  1. Functional Status and Quality of Life in Survivors of Extracorporeal Membrane Oxygenation After the Norwood Operation.

Friedland-Little JM, Uzark K, Yu S, Lowery R, Aiyagari R, Hirsch-Romano JC.

Ann Thorac Surg. 2017 Jun;103(6):1950-1955. doi: 10.1016/j.athoracsur.2016.11.015. Epub 2017 Feb 21.

PMID: 28223051

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  1. Question 2 Is levosimendan better than milrinone in preventing post operative low cardiac output syndrome and improving cardiac function in children with congenital heart disease?

Udayasankar S.

Arch Dis Child. 2017 Jun;102(6):590-592. doi: 10.1136/archdischild-2017-312660. No abstract available.

PMID: 28536187

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  1. Tetralogy of Fallot Surgical Repair: Shunt Configurations, Ductus Arteriosus and the Circle of Willis.

Piskin S, Unal G, Arnaz A, Sarioglu T, Pekkan K.

Cardiovasc Eng Technol. 2017 Jun;8(2):107-119. doi: 10.1007/s13239-017-0302-5. Epub 2017 Apr 5.

PMID: 28382440 Free PMC Article

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  1. Improved long-term outcomes in double-inlet left ventricle and tricuspid atresia with transposed great arteries: systemic outflow tract obstruction present at birth defines long-term outcome.

Franken LC, Admiraal M, Verrall CE, Zannino D, Ayer JG, Iyengar AJ, Cole AD, Sholler GF, D’Udekem Y, Winlaw DS.

Eur J Cardiothorac Surg. 2017 Jun 1;51(6):1051-1057. doi: 10.1093/ejcts/ezx022.

PMID: 28329058

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  1. Ventricular assist devices for the failing univentricular circulation.

Buratto E, Shi WY, Ye XT, Konstantinov IE.

Expert Rev Med Devices. 2017 Jun;14(6):449-459. doi: 10.1080/17434440.2017.1332523. Epub 2017 May 26.

PMID: 28532240

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  1. Early mortality and concomitant procedures related to Fontan conversion: Quantitative analysis.

Brida M, Baumgartner H, Gatzoulis MA, Diller GP.

Int J Cardiol. 2017 Jun 1;236:132-137. doi: 10.1016/j.ijcard.2017.01.111. Epub 2017 Jan 25.

PMID: 28132780

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  1. Heart transplantation using a donor with partial anomalous pulmonary venous connection and atrial septal defect.

de Beco G, Duisit J, Poncelet AJ.

Interact Cardiovasc Thorac Surg. 2017 Jun 1;24(6):978-979. doi: 10.1093/icvts/ivw440.

PMID: 28379508

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  1. National trends and variability in blood utilization in paediatric cardiac surgery.

Karimi M, Sullivan JM, Lerer T, Hronek C.

Interact Cardiovasc Thorac Surg. 2017 Jun 1;24(6):938-943. doi: 10.1093/icvts/ivw439.

PMID: 28369475

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  1. Interventricular septal hematoma following repair of a ventricular septal defect.

Yamazawa H, Takeda A, Nakajima H, Tachibana T, Aoki M.

J Card Surg. 2017 Jun;32(6):390-393. doi: 10.1111/jocs.13145. Epub 2017 May 11.

PMID: 28493392

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  1. Obstructed Infradiaphragmatic Total Anomalous Pulmonary Venous Return in a 13-Day-Old Infant Presenting Acutely to the Emergency Department: A Case Report.

Siacunco EA, Pacheco GS, Woolridge DP.

J Emerg Med. 2017 Jun;52(6):e239-e243. doi: 10.1016/j.jemermed.2017.01.051. Epub 2017 Mar 10.

PMID: 28285866

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  1. The use of neonatal extracorporeal life support in pediatric cardiac intensive care unit.

Öztürk E, Yıldız O, Çine N, Tüzün B, Onan S, Ergül Y, Güzeltaş A, Haydin S, Yeniterzi M, Bakır İ.

J Matern Fetal Neonatal Med. 2017 Jun;30(12):1397-1401. doi: 10.1080/14767058.2016.1214706. Epub 2016 Aug 10.

PMID: 27432486

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  1. Total cavopulmonary connection with a new bioabsorbable vascular graft: First clinical experience.

Bockeria LA, Svanidze O, Kim A, Shatalov K, Makarenko V, Cox M, Carrel T.

J Thorac Cardiovasc Surg. 2017 Jun;153(6):1542-1550. doi: 10.1016/j.jtcvs.2016.11.071. Epub 2017 Feb 7.

PMID: 28314534

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  1. Geometry and growth of the reconstructed aorta in patients with hypoplastic left heart syndrome and variants.

Haller C, Chetan D, Saedi A, Parker R, Van Arsdell GS, Honjo O.

J Thorac Cardiovasc Surg. 2017 Jun;153(6):1479-1487.e1. doi: 10.1016/j.jtcvs.2017.02.011. Epub 2017 Feb 14.

PMID: 28291606

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  1. Hands-on surgical training of congenital heart surgery using 3-dimensional print models.

Yoo SJ, Spray T, Austin EH 3rd, Yun TJ, van Arsdell GS.

J Thorac Cardiovasc Surg. 2017 Jun;153(6):1530-1540. doi: 10.1016/j.jtcvs.2016.12.054. Epub 2017 Feb 9.

PMID: 28268011

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  1. Variation in extubation failure rates after neonatal congenital heart surgery across Pediatric Cardiac Critical Care Consortium hospitals.

Benneyworth BD, Mastropietro CW, Graham EM, Klugman D, Costello JM, Zhang W, Gaies M.

J Thorac Cardiovasc Surg. 2017 Jun;153(6):1519-1526. doi: 10.1016/j.jtcvs.2016.12.042. Epub 2017 Feb 4.

PMID: 28259455

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  1. Resource Utilization Associated with Extracardiac Co-morbid Conditions Following Congenital Heart Surgery in Infancy.

Tuomela KE, Gordon JB, Cassidy LD, Johaningsmeir S, Ghanayem NS.

Pediatr Cardiol. 2017 Jun;38(5):1065-1070. doi: 10.1007/s00246-017-1620-y. Epub 2017 Apr 29.

PMID: 28456828

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  1. Measures of and changes in heart rate variability in pediatric heart transplant recipients.

Williams T, Tang X, Gilmore G, Gossett J, Knecht KR.

Pediatr Transplant. 2017 Jun;21(4). doi: 10.1111/petr.12894. Epub 2017 Feb 8.

PMID: 28181355

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  1. Sir William Harvey, Congenital Heart Disease and Anesthesia.

Twite MD.

Semin Cardiothorac Vasc Anesth. 2017 Jun;21(2):121-122. doi: 10.1177/1089253217704509. No abstract available.

PMID: 28506196

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  1. Surgical Considerations in Total Anomalous Pulmonary Venous Connection.

Shaw FR, Chen JM.

Semin Cardiothorac Vasc Anesth. 2017 Jun;21(2):132-137. doi: 10.1177/1089253216688535. Epub 2017 Jan 20.

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  1. Total Anomalous Pulmonary Venous Connection: Preoperative Anatomy, Physiology, Imaging, and Interventional Management of Postoperative Pulmonary Venous Obstruction.

Files MD, Morray B.

Semin Cardiothorac Vasc Anesth. 2017 Jun;21(2):123-131. doi: 10.1177/1089253216672442. Epub 2016 Nov 29.

PMID: 27831520

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  1. Perioperative and Anesthetic Considerations in Total Anomalous Pulmonary Venous Connection.

Ross FJ, Joffe D, Latham GJ.

Semin Cardiothorac Vasc Anesth. 2017 Jun;21(2):138-144. doi: 10.1177/1089253216672012. Epub 2016 Sep 29.

PMID: 27694572

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  1. Effect of Induction Therapy on Graft Survival in Primary Pediatric Heart Transplantation: A Propensity Score Analysis of the UNOS Database.

Butts R, Davis M, Savage A, Burnette A, Kavarana M, Bradley S, Atz A, Nietert PJ.

Transplantation. 2017 Jun;101(6):1228-1233. doi: 10.1097/TP.0000000000001285.

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  1. Deposition of mannose-binding lectin and ficolins and activation of the lectin pathway of complement on the surface of polyurethane tubing used for cardiopulmonary bypass.

Eppa Ł, Pągowska-Klimek I, Świerzko AS, Moll M, Krajewski WR, Cedzyński M.

J Biomed Mater Res B Appl Biomater. 2017 May 31. doi: 10.1002/jbm.b.33933. [Epub ahead of print]

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  1. Impact of contrast exposure from computed tomography angiography on acute kidney injury after neonatal cardiopulmonary bypass surgery.

Carlo WF, Clark ST, Borasino S, Alten JA.

Congenit Heart Dis. 2017 May 30. doi: 10.1111/chd.12482. [Epub ahead of print]

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  1. Image of a left atrial mass after a cardiopulmonary bypass in a child.

Hadeed K, Leobon B, Dulac Y, Acar P.

Echocardiography. 2017 May 30. doi: 10.1111/echo.13583. [Epub ahead of print]

PMID: 28560785

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  1. Complex effects of high-flow nasal cannula therapy on hemodynamics in the pediatric patient after cardiac surgery.

Inata Y, Takeuchi M.

J Intensive Care. 2017 May 30;5:30. doi: 10.1186/s40560-017-0227-y. eCollection 2017.

PMID: 28572979 Free PMC Article

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  1. Clinical feasibility of pre-operative neurodevelopmental assessment of infants undergoing open heart surgery.

Campbell M, Rabbidge B, Ziviani J, Sakzewski L.

J Paediatr Child Health. 2017 May 30. doi: 10.1111/jpc.13565. [Epub ahead of print]

PMID: 28557106

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  1. Differential expression of microRNAs following cardiopulmonary bypass in children with congenital heart diseases.

Abu-Halima M, Poryo M, Ludwig N, Mark J, Marsollek I, Giebels C, Petersen J, Schäfers HJ, Grundmann U, Pickardt T, Keller A, Meese E, Abdul-Khaliq H.

J Transl Med. 2017 May 30;15(1):117. doi: 10.1186/s12967-017-1213-9.

PMID: 28558735 Free PMC Article

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  1. Single-stage repair for multiple muscular septal defects: a single-centre experience across 16 years.

Shetty V, Shetty D, Punnen J, Chattuparambil B, Whitlock R, Bohra D.

Interact Cardiovasc Thorac Surg. 2017 May 29. doi: 10.1093/icvts/ivx105. [Epub ahead of print]

PMID: 28575225

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  1. Ebstein’s anomaly in adults: Modified cone reconstruction of the tricuspid valve is associated with promising outcomes.

Belli E, Rabot M, Petit J, Gouton M.

Arch Cardiovasc Dis. 2017 May 26. pii: S1875-2136(17)30094-3. doi: 10.1016/j.acvd.2017.03.003. [Epub ahead of print]

PMID: 28566198

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  1. Restrictive enlargement of the pulmonary annulus at repair of tetralogy of Fallot: a comparative 10-year follow-up study†.

Logoteta J, Dullin L, Hansen JH, Rickers C, Salehi Ravesh M, Al Bulushi A, Kristo I, Wegner P, Schumacher M, Attmann T, Scheewe J, Kramer HH.

Eur J Cardiothorac Surg. 2017 May 26. doi: 10.1093/ejcts/ezx143. [Epub ahead of print]

PMID: 28549113

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  1. Risk of Respiratory Syncytial Virus Hospitalization in the First and Second Years of Life in Pediatric Patients with Congenital Heart Disease.

Friedman D, Wong PC.

Pediatr Cardiol. 2017 May 23. doi: 10.1007/s00246-017-1634-5. [Epub ahead of print] No abstract available.

PMID: 28536747

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  1. Current trends in racial, ethnic, and healthcare disparities associated with pediatric cardiac surgery outcomes.

Peterson JK, Chen Y, Nguyen DV, Setty SP.

Congenit Heart Dis. 2017 May 22. doi: 10.1111/chd.12475. [Epub ahead of print]

PMID: 28544396

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  1. Acute Kidney Injury Following Cardiopulmonary Bypass in Children - Risk Factors and Outcomes.

Lee SH, Kim SJ, Kim HJ, Son JS, Lee R, Yoon TG.

Circ J. 2017 May 17. doi: 10.1253/circj.CJ-17-0075. [Epub ahead of print]

PMID: 28515370 Free Article

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  1. Post-Operative Chylothorax in Patients With Congenital Heart Disease.

Savla JJ, Itkin M, Rossano JW, Dori Y.

J Am Coll Cardiol. 2017 May 16;69(19):2410-2422. doi: 10.1016/j.jacc.2017.03.021.

PMID: 28494978

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  1. Redo coronary bypass grafting for congenital left main coronary atresia: a case report.

Yajima S, Toda K, Nishi H, Yoshioka D, Nakamura T, Miyagawa S, Yoshikawa Y, Fukushima S, Sawa Y.

J Cardiothorac Surg. 2017 May 15;12(1):26. doi: 10.1186/s13019-017-0588-2.

PMID: 28506276 Free PMC Article

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  1. When Is It Better to Wait? Surgical Timing and Recurrence Risk for Children Undergoing Repair of Subaortic Stenosis.

Anderson BR, Tingo JE, Glickstein JS, Chai PJ, Bacha EA, Torres AJ.

Pediatr Cardiol. 2017 May 15. doi: 10.1007/s00246-017-1622-9. [Epub ahead of print]

PMID: 28508142

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  1. Elevated cranial ultrasound resistive indices are associated with improved neurodevelopmental outcomes one year after pediatric cardiac surgery: A single center pilot study.

Jenks CL, Hernandez A, Stavinoha PL, Morris MC, Tian F, Liu H, Garg P, Forbess JM, Koch J.

Heart Lung. 2017 May 13. pii: S0147-9563(17)30027-4. doi: 10.1016/j.hrtlng.2017.04.009. [Epub ahead of print]

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  1. Extra-anatomical bypass in complex and recurrent aortic coarctation and hypoplastic arch†.

Delmo Walter EM, Javier MFDM, Hetzer R.

Interact Cardiovasc Thorac Surg. 2017 May 11. doi: 10.1093/icvts/ivx115. [Epub ahead of print]

PMID: 28498910

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  1. Comparison of enteral versus intravenous potassium supplementation in hypokalaemia in paediatric patients in intensive care post cardiac surgery: open-label randomised equivalence trial (EIPS).

Rehman Siddiqu NU, Merchant Q, Hasan BS, Rizvi A, Amanullah M, Rehmat A, Ul Haq A.

BMJ Open. 2017 May 10;7(5):e011179. doi: 10.1136/bmjopen-2016-011179.

PMID: 28495809 Free Article

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  1. The Total Artificial Heart in End-Stage Congenital Heart Disease.

Villa CR, Morales DLS.

Front Physiol. 2017 May 9;8:131. doi: 10.3389/fphys.2017.00131. eCollection 2017. Review.

PMID: 28536530 Free PMC Article

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  1. Perioperative experience of parents whose children undergo cardiac surgery: are we delivering?

Byrne K.

Nurs Child Young People. 2017 May 9;29(4):22. doi: 10.7748/ncyp.29.4.22.s22.

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  1. Pilot Study Comparing Closed Versus Open Tracheal Suctioning in Postoperative Neonates and Infants With Complex Congenital Heart Disease.

Tume LN, Baines PB, Guerrero R, Hurley MA, Johnson R, Kalantre A, Ramaraj R, Ritson PC, Walsh L, Arnold PD.

Pediatr Crit Care Med. 2017 May 9. doi: 10.1097/PCC.0000000000001192. [Epub ahead of print]

PMID: 28489637

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  1. Fluid Overload and Cumulative Thoracostomy Output Are Associated With Surgical Site Infection After Pediatric Cardiothoracic Surgery.

Sochet AA, Nyhan A, Spaeder MC, Cartron AM, Song X, Klugman D, Brown AT.

Pediatr Crit Care Med. 2017 May 8. doi: 10.1097/PCC.0000000000001193. [Epub ahead of print]

PMID: 28486386

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  1. The ordeal of left atrioventricular valve replacement in children under 1 year of age†.

Sawan EB, Brink J, Soquet J, Liava’A M, Brizard CP, Konstantinov IE, d’Udekem Y.

Interact Cardiovasc Thorac Surg. 2017 May 2. doi: 10.1093/icvts/ivx114. [Epub ahead of print]

PMID: 28472474

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  1. The utility of computed tomographic angiography in a neonate on extracorporeal membrane oxygenation with extreme cyanosis after Blalock-Taussig shunt.

Rames JD, Kavarana MN, Schoepf UJ, Hlavacek AM.

Ann Pediatr Cardiol. 2017 May-Aug;10(2):209-211. doi: 10.4103/0974-2069.205137.

PMID: 28566834 Free PMC Article

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  1. Mid-term outcomes of surgical repair for anomalous origin of the left coronary artery from the pulmonary artery: In infants, children and adults.

Dehaki MG, Al-Dairy A, Rezaei Y, Ghavidel AA, Omrani G, Givtaj N, Afjehi RS, Tatari H, Jalali AH, Mahdavi M.

Ann Pediatr Cardiol. 2017 May-Aug;10(2):137-143. doi: 10.4103/0974-2069.205140.

PMID: 28566821 Free PMC Article

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  1. Three-dimensional-printed cardiac prototypes aid surgical decision-making and preoperative planning in selected cases of complex congenital heart diseases: Early experience and proof of concept in a resource-limited environment.

Kappanayil M, Koneti NR, Kannan RR, Kottayil BP, Kumar K.

Ann Pediatr Cardiol. 2017 May-Aug;10(2):117-125. doi: 10.4103/apc.APC_149_16.

PMID: 28566818 Free PMC Article

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  1. Hybrid Nuss Procedure for Pectus Excavatum With Severe Retrosternal Adhesions After Sternotomy.

Li S, Yang D, Ma Y, Tang ST, Yang L, Li S, Cao G, Li K, Zhang X, Hu X.

Ann Thorac Surg. 2017 May;103(5):1573-1577. doi: 10.1016/j.athoracsur.2016.10.001. Epub 2016 Dec 6.

PMID: 27938890

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  1. Clinical Assessment of Histidine-Tryptophan-Ketoglutarate Solution and Modified St. Thomas’ Solution in Pediatric Cardiac Surgery of Tetralogy of Fallot.

Wang ZH, An Y, Du MC, Qin TJ, Liu YB, Xu HZ, Yang LQ.

Artif Organs. 2017 May;41(5):470-475. doi: 10.1111/aor.12771. Epub 2016 Nov 22.

PMID: 27878830

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  1. Causes of interruptions in postoperative enteral nutrition in children with congenital heart disease.

Qi J, Li Z, Cun Y, Li X.

Asia Pac J Clin Nutr. 2017 May;26(3):402-405. doi: 10.6133/apjcn.032016.05.

PMID: 28429903 Free Article

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  1. Early or late fresh frozen plasma administration in newborns and small infants undergoing cardiac surgery: the APPEAR randomized trial.

Bianchi P, Cotza M, Beccaris C, Silvetti S, Isgrò G, Pomè G, Giamberti A, Ranucci M; Surgical and Clinical Outcome REsearch (SCORE) group.

Br J Anaesth. 2017 May 1;118(5):788-796. doi: 10.1093/bja/aex069.

PMID: 28510741

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  1. Creating a lesion-specific “roadmap” for ambulatory care following surgery for complex congenital cardiac disease.

Wernovsky G, Lihn SL, Olen MM.

Cardiol Young. 2017 May;27(4):648-662. doi: 10.1017/S1047951116000974. Epub 2016 Jul 4.

PMID: 27373527

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  1. Utility of a standardized postcardiopulmonary bypass epicardial echocardiography protocol for stage I Norwood palliation.

Stern KWD, Gauvreau K, Emani S, Geva T.

Congenit Heart Dis. 2017 May;12(3):350-356. doi: 10.1111/chd.12450. Epub 2017 Feb 16.

PMID: 28205344

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  1. Surgical planning for a complex double-outlet right ventricle using 3D printing.

Bhatla P, Tretter JT, Chikkabyrappa S, Chakravarti S, Mosca RS.

Echocardiography. 2017 May;34(5):802-804. doi: 10.1111/echo.13512. Epub 2017 Mar 19.

PMID: 28317159

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Select item 28329109

 

  1. Impact of early Fontan completion on postoperative outcomes in patients with a functional single ventricle.

Ono M, Burri M, Cleuziou J, Pabst von Ohain J, Beran E, Strbad M, Hager A, Hörer J, Schreiber C, Lange R.

Eur J Cardiothorac Surg. 2017 May 1;51(5):995-1002. doi: 10.1093/ejcts/ezx019.

PMID: 28329109

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Select item 28327570

 

  1. Healthcare providers’ caring: Nothing is too small for parents and children hospitalized for heart surgery.

Wei H, Roscigno CI, Swanson KM.

Heart Lung. 2017 May – Jun;46(3):166-171. doi: 10.1016/j.hrtlng.2017.01.007. Epub 2017 Feb 22.

PMID: 28237272

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Select item 28373593

 

  1. Hospital-acquired Infection: Prevalence and Outcome in Infants Undergoing Open Heart Surgery in the Present Era.

Sahu MK, Siddharth CB, Devagouru V, Talwar S, Singh SP, Chaudhary S, Airan B.

Indian J Crit Care Med. 2017 May;21(5):281-286. doi: 10.4103/ijccm.IJCCM_62_17.

PMID: 28584431

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Select item 28539207

 

  1. Le-Compte maneuver in surgical correction of absent pulmonary valve. Does it improve severe bronchial compression?

Sarıtaş B, Özker E, Sarısoy Ö, Şahin M, Gümüş B, Ayabakan C.

Int J Cardiol. 2017 May 1;234:151-153. doi: 10.1016/j.ijcard.2017.01.061. Epub 2017 Jan 6. No abstract available.

PMID: 28094129

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  1. Early to mid-term results after total cavopulmonary connection performed in the second decade of life.

Metras A, Fouilloux V, Al-Yamani M, Roques X, Macé L, Thambo JB, Metras D, Kreitmann B, Roubertie F.

Interact Cardiovasc Thorac Surg. 2017 May 1;24(5):762-767. doi: 10.1093/icvts/ivw427.

PMID: 28453799

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Select item 28453795

 

  1. Closing the gap in paediatric ventricular assist device therapy with the Berlin Heart EXCOR® 15-ml pump†.

De Rita F, Griselli M, Sandica E, Miera O, Karimova A, d’Udekem Y, Goldwasser R, Januszewska K, Amodeo A, Jurrmann N, Ersel S, Menon AK.

Interact Cardiovasc Thorac Surg. 2017 May 1;24(5):768-771. doi: 10.1093/icvts/ivw437.

PMID: 28453795

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  1. A ferromagnetic surgical system reduces phrenic nerve injury in redo congenital cardiac surgery.

Shinkawa T, Holloway J, Tang X, Gossett JM, Imamura M.

Interact Cardiovasc Thorac Surg. 2017 May 1;24(5):802-803. doi: 10.1093/icvts/ivw444.

PMID: 28329107

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  1. Non-invasive cardiac output monitor validation study in pediatric cardiac surgery patients.

Tirotta CF, Lagueruela RG, Madril D, Velis E, Ojito J, Monroe D, Aguero D, Irizarry M, McBride J, Hannan RL, Burke RP.

J Clin Anesth. 2017 May;38:129-132. doi: 10.1016/j.jclinane.2017.02.001. Epub 2017 Feb 12.

PMID: 28372651

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  1. Microvascular surgery in the congenital cardiac patient: A case series exploring feasibility and practical applications.

LoGiudice JA, Adamson K, Ghanayem N, Woods RK, Mitchell ME.

J Plast Reconstr Aesthet Surg. 2017 May;70(5):639-645. doi: 10.1016/j.bjps.2017.02.002. Epub 2017 Feb 17.

PMID: 28325567

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Select item 28242014

 

  1. Evaluation of commissural malalignment of aortic-pulmonary sinus using cardiac CT for arterial switch operation: comparison with transthoracic echocardiography.

Bang JH, Park JJ, Goo HW.

Pediatr Radiol. 2017 May;47(5):556-564. doi: 10.1007/s00247-017-3786-0. Epub 2017 Feb 27.

PMID: 28243677

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  1. [Prognostic factors of postoperative severe hyperglycemia after cardiac surgery in pediatric patients].

Marín-Vivas RR, Saldívar-Müller CE, Sánchez-Bañuelos CC, Flores-Lujano J, Núñez-Enríquez JC.

Rev Med Inst Mex Seguro Soc. 2017 May-Jun;55(3):324-329. Spanish.

PMID: 28440986

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  1. Surgical Considerations in Atrioventricular Canal Defects.

Malik M, Khalid Nuri M.

Semin Cardiothorac Vasc Anesth. 2017 May 1:1089253217708622. doi: 10.1177/1089253217708622. [Epub ahead of print]

PMID: 28482733

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  1. Outcomes and Prognostic Factors for Adult Patients With Congenital Heart Disease Undergoing Primary or Reoperative Systemic Atrioventricular Valve Surgery.

Stephens EH, Han J, Ginns J, Rosenbaum M, Chai P, Bacha E, Kalfa D.

World J Pediatr Congenit Heart Surg. 2017 May;8(3):346-353. doi: 10.1177/2150135117692974.

PMID: 28520541

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Select item 28520537

 

  1. Anomalous Origin of Right Coronary Artery From Left Coronary Sinus-13 Cases Treated With the Reimplantation Technique.

Cubero A, Crespo A, Hamzeh G, Cortes A, Rivas D, Aramendi JI.

World J Pediatr Congenit Heart Surg. 2017 May;8(3):315-320. doi: 10.1177/2150135116688172.

PMID: 28520537

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Select item 27162188

 

  1. Reconstruction of a Previously Repaired Aortic Valve Destroyed by Infective Endocarditis: Case Report.

Chalela T, Hraska V.

World J Pediatr Congenit Heart Surg. 2017 May;8(3):408-410. doi: 10.1177/2150135116636571. Epub 2016 May 9.

PMID: 27162188

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  1. Letter by Ghimire Regarding Article, “Total Anomalous Pulmonary Venous Connection: The Current Management Strategies in a Pediatric Cohort of 768 Patients”.

Ghimire LV.

Circulation. 2017 May 30;135(22):e1093-e1094. doi: 10.1161/CIRCULATIONAHA.116.026819. No abstract available.

PMID: 28559501

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  1. Pediatric Extracorporeal Life Support Organization Registry International Report 2016.

Barbaro RP, Paden ML, Guner YS, Raman L, Ryerson LM, Alexander P, Nasr VG, Bembea MM, Rycus PT, Thiagarajan RR; ELSO member centers.

ASAIO J. 2017 May 23. doi: 10.1097/MAT.0000000000000603. [Epub ahead of print]

PMID: 28557863

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  1. Ventricular Energetics in Pediatric Left Ventricular Assist Device Patients: A Retrospective Clinical Study.

Di Molfetta A, Ferrari G, Iacobelli R, Filippelli S, Di Chiara L, Guccione P, Amodeo A.

ASAIO J. 2017 May 16. doi: 10.1097/MAT.0000000000000595. [Epub ahead of print]

PMID: 28514263

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  1. Acute and Long-Term Effects of Left Ventricular Assist Device Support on Right Ventricular Function in Children with Pediatric Pulsatile Ventricular Assist Devices.

Iacobelli R, Di Molfetta A, Brancaccio G, Filippelli S, Morelli S, Natali B, Toscano A, Drago F, Amodeo A.

ASAIO J. 2017 May 12. doi: 10.1097/MAT.0000000000000596. [Epub ahead of print]

PMID: 28509675

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Select item 28219978

 

  1. Metrics to Assess Extracorporeal Membrane Oxygenation Utilization in Pediatric Cardiac Surgery Programs.

Bratton SL, Chan T, Barrett CS, Wilkes J, Ibsen LM, Thiagarajan RR.

Pediatr Crit Care Med. 2017 May 11. doi: 10.1097/PCC.0000000000001205. [Epub ahead of print]

PMID: 28498231

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Select item 28496132

 

  1. The utility of computed tomographic angiography in a neonate on extracorporeal membrane oxygenation with extreme cyanosis after Blalock-Taussig shunt.

Rames JD, Kavarana MN, Schoepf UJ, Hlavacek AM.

Ann Pediatr Cardiol. 2017 May-Aug;10(2):209-211. doi: 10.4103/0974-2069.205137.

PMID: 28566834 Free PMC Article

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Select item 28566830

 

  1. Three-dimensional-printed cardiac prototypes in complex congenital cardiac defects: New technology with exciting possibilities.

Sundararaghavan S.

Ann Pediatr Cardiol. 2017 May-Aug;10(2):114-116. doi: 10.4103/apc.APC_48_17. No abstract available.

PMID: 28566817 Free PMC Article

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  1. Successful Biventricular Conversion Late After Primary One and One-Half Ventricle Repair.

Hoashi T, Kitano M, Kagisaki K, Ichikawa H.

Ann Thorac Surg. 2017 May;103(5):e447-e448. doi: 10.1016/j.athoracsur.2016.10.073.

PMID: 28431723

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  1. Late outcomes in children with Shone’s complex: a single-centre, 20-year experience.

Nicholson GT, Kelleman MS, De la Uz CM, Pignatelli RH, Ayres NA, Petit CJ.

Cardiol Young. 2017 May;27(4):697-705. doi: 10.1017/S1047951116001104. Epub 2016 Jul 26.

PMID: 27456367

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  1. Creating a lesion-specific “roadmap” for ambulatory care following surgery for complex congenital cardiac disease.

Wernovsky G, Lihn SL, Olen MM.

Cardiol Young. 2017 May;27(4):648-662. doi: 10.1017/S1047951116000974. Epub 2016 Jul 4.

PMID: 27373527

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  1. Cardiac transplantation in a neonate-First case in Switzerland and European overview.

Schweiger M, Stiasny B, Immer F, Bürki C, Schmiady M, Dave H, Cavigelli-Brunner A, Kretschmar O, Cannizzaro V, Hübler M.

Clin Transplant. 2017 May;31(5). doi: 10.1111/ctr.12935. Epub 2017 Apr 4.

PMID: 28235145

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Select item 28580610

 

  1. Hypoplastic left heart syndrome: a novel surgical strategy for small-volume centres?

Pontailler M, Gaudin R, Lenoir M, Haydar A, Kraiche D, Bonnet D, Vouhé P, Raisky O.

Eur J Cardiothorac Surg. 2017 May 1;51(5):1003-1008. doi: 10.1093/ejcts/ezx021.

PMID: 28329111

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  1. Impact of early Fontan completion on postoperative outcomes in patients with a functional single ventricle.

Ono M, Burri M, Cleuziou J, Pabst von Ohain J, Beran E, Strbad M, Hager A, Hörer J, Schreiber C, Lange R.

Eur J Cardiothorac Surg. 2017 May 1;51(5):995-1002. doi: 10.1093/ejcts/ezx019.

PMID: 28329109

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  1. Thrombolysis of prosthetic mitral valve thrombosis in an infant.

Hage A, Jacques F, Chetaille P, Bourdages M, Cloutier K, Perron J, Houde C.

J Card Surg. 2017 May;32(5):310-312. doi: 10.1111/jocs.13135.

PMID: 28463467

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  1. Interaction of older donor age and survival after weight-matched pediatric heart transplantation.

Westbrook TC, Morales DLS, Khan MS, Bryant R, Castleberry C, Chin C, Zafar F.

J Heart Lung Transplant. 2017 May;36(5):554-558. doi: 10.1016/j.healun.2016.11.009. Epub 2016 Dec 1.

PMID: 28073609

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  1. The End-of-Life Experience of Pediatric Heart Transplant Recipients.

Hollander SA, Dykes JC, Chen S, Barkoff L, Sourkes B, Cohen H, Rosenthal DN, Bernstein D, Kaufman BD.

J Pain Symptom Manage. 2017 May;53(5):927-931. doi: 10.1016/j.jpainsymman.2016.12.334. Epub 2017 Jan 4.

PMID: 28063864

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Select item 28410087

 

  1. Ventricular Septal Defect Creation: A Viable Option to Decompress a Large Non-Systemic Left Ventricle in a Fontan Patient.

Elderie A, Reddy A, Zafar F, Hirsch R, Morales DLS.

World J Pediatr Congenit Heart Surg. 2017 May;8(3):400-403. doi: 10.1177/2150135116634291. Epub 2016 May 6.

PMID: 27154798

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ACHD Featured Articles of May 2017

Adult Congenital Heart Reviews of May 2017 Manuscripts

 

Diagnostic value of Doppler echocardiography for identifying hemodynamic significant pulmonary valve regurgitation in tetralogy of Fallot: comparison with cardiac MRI.

Beurskens NEG, Gorter TM, Pieper PG, Hoendermis ES, Bartelds B, Ebels T, Berger RMF, Willems TP, van Melle JP.

Int J Cardiovasc Imaging. 2017 May 31. doi: 10.1007/s10554-017-1165-4. [Epub ahead of print]

PMID: 28567705

 

 

Take Home Points:

 

  • The echo parameters of pulmonary regurgitation pressure half time (PHT) < 100 ms and pulmonary regurgitation jet width/annulus ratio ≥1/3 were sensitive and specific at identifying significant pulmonary regurgitation and correlated well with cardiac MRI derived pulmonary regurgitant fraction ≥20%. These 2 echo parameters were particularly accurate when combined, with a sensitivity and specificity of 97% and 100%, respectively.

 

 

jokhadar-maanCommentary from Dr. Maan Jokhadar (Atlanta), section editor of ACHD Journal Watch:

Complete repair of tetralogy of Fallot (TOF) often results in pulmonary regurgitation (PR) and gradual right ventricular volume overload and its consequences of right ventricle dilation, dysfunction, and arrhythmia.  Eventual pulmonary valve replacement is often necessary to preserve right ventricle function and improve functional outcome. Therefore, the reliable quantification of PR is a critical component in the decision making for pulmonary valve replacement. Currently, PR quantification after TOF repair is most reliably assessed with phase contrast magnetic resonance imaging (MRI).  More reliable PR quantification with echocardiography has obvious advantages that include cost savings, mobility, comfort, and safety in the setting pacemakers and devices.

 

Dr. Beurskens and colleagues from the Groningen in The Netherlands performed a retrospective analysis of 97 patients with repaired TOF who had a cardiac MRI and echocardiogram within 3-months of each other between 2007 and 2013. The mean age was about 28 years.

 

Four echo parameters were compared to cardiac MRI derived PR fraction (PRF), which was considered the gold standard. Mild PR was a PRF <20% and significant PR was PRF ≥20%. The mean PRF was 29.4±15.7%. The findings were as follows:

 

Pressure half-time (PHT) <100 ms had a sensitivity and specificity of 93% and 75%, respectively for identifying significant PR (C-statistic 0.82).  PHT was measured by drawing a line along the continuous wave (CW) Doppler PR signal.

 

PR Jet/annulus ratio ≥1/3 had a sensitivity and specificity of 96% and 75%, respectively. (C-statistic 0.87). The jet diameter was measured during early diastole using Color Doppler while avoiding aliasing by adjusting the Nyquist limit. The annulus diameter was measured in the same view using 2D images without color. Both measurements were used to calculate the jet/annulus ratio.

 

Combined jet/annulus ratio ≥1/3 and PHT <100 ms was highly accurate in identifying PRF≥20%, with sensitivity and specificity of 97% and 100%, respectively.

 

Less helpful parameters:

 

PR index (PRi) <0.77 had a sensitivity and specificity of 66% and 54%, respectively (C-statistic 0.63). PRi was calculated using the PR time as percentage of the total diastolic time, derived from the CW Doppler tracings. Lower PRi corresponds with more severe PR.

 

Diastolic to systolic time velocity integral (DSTVI) >0.49 had sensitivity and specificity of 84% and 33%, respectively, (C-statistic 0.56). DSTVI was calculated by dividing the surface area of the pulse-wave (PW) Doppler diastolic flow curve by the surface area of the systolic flow curve. PW Doppler sampling was at the level of the main pulmonary artery.

 

Conclusions:

PHT and jet/annulus ratio appear to be useful tools in the echo assessment of PR after TOF repair. However, these findings and criteria require validation and possible refinement and additional studies are needed to determine whether using these echo parameters translates to clinical benefit, particularly as it applies to timing of pulmonary valve replacement.

 

 

 

Renal resistive index reflects Fontan pathophysiology and predicts mortality.

Ohuchi H, Negishi J, Hayama Y, Miyazaki A, Shiraishi I, Ichikawa H.

Heart 2017; 0: 1-7. Doi : 10.1136/heartjnl-2016-310812

PMID: 28465331

 

 

Take Home Points:

 

  • Higher renal resistive index (RRI), currently used and validated to monitor end-organ damage in patients with diabetes and hypertension, is associated with poorer functional capacity, neuro-hormonal activation, and diminished renal function in Fontan subjects.
  • RRI ≥ 0.81 has a strong prognostic value for all–cause mortality in Fontan patients.

 

 

Leong Ming ChernCommentary from Dr. MC Leong (Kuala Lumpur), section editor of ACHD Journal Watch: Renal resistive index (RRI), which is calculated using the formula: RRI = 100 x (1- end diastolic velocity/ peak systolic velocity), has been shown to be a marker of cardiovascular damage and is a useful tool for monitoring end-organ damage as well as the predicted mortality for patients with hypertension. In patients with congenital heart disease, it has been demonstrated to be a useful tool for identifying severe heart failure, and identify those with a worse prognosis. This study aimed to analyze the significance of RRI in patients with Fontan with respect to invasive hemodynamics, neurohumoral activation (plasma norepinephrine concentration, brain natriuretic peptide and plasma renin activity), exercise capacity (peak VO2), renal function (24-hour creatinine clearance), liver function and glucose intolerance.

 

280 clinically stable Fontan patients, aged 6 years and above were assessed between March 2007 and September 2016. Mean follow up duration is 32±22 months. Eighteen patients died during follow up. Higher RRI was correlated with higher NYHA functional class, presence of protein losing enteropathy, pulmonary AVM’s, arrhythmia, BNP, plasma renin activity and norepinephrine levels.  RRI was however inversely correlated with Peak VO2 and serum Albumin levels. A cut-off value of RRI ≥ 0.81 was strongly predictive of mortality. On multivariate analyses, RRI ≥ 0.81 was the only independent predictor of mortality (HR: 12.0; 95% CI: 3.4-50.1; p<0.0001).

ACHD 1 May

May ACHD 2

May ACHD 3

Effects of long-term iloprost treatment on right ventricular function in patients with Eisenmenger syndrome.

Chon MK, Cho KI, Cha KS, Seo JS, Kim DS.

J Cardiol. 2017 May;69(5):741-746. doi: 10.1016/j.jjcc.2016.07.002. Epub 2016 Aug 1.

PMID: 27492657

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Take Home Points:

 

  • Eisenmenger syndrome [ES] is associated with significant morbidity and mortality.
  • Long term [after 48 weeks of treatment] inhaled iloprost therapy significantly improved both clinical and echocardiographic parameters.
  • These included significant improvements in mean and systolic pulmonary artery pressures, RV function parameters (Improved RV MPI, RV FAC, tricuspid annular peak systolic velocity), WHO functional classification, 6MWD and NT-proBNP.

 

 

Blanche CupidoCommentary by Dr. Blanche Cupido (Cape Town), section editor of ACHD Journal WatchThis is a prospective multicenter study that evaluated the effect of inhaled iloprost therapy (given for a 48-week period) on RV function and clinical status in patients with ES. Although ES generally carries a better prognosis than idiopathic PAH, morbidity and mortality remain significant in this group as well. Although a number of drugs currently exist, few of them have been demonstrated beneficial in ES.

 

Eleven patients with ES (right to left shunt present at rest) were enrolled between December 2010 and November 2012. Patients who had concomitant severe LV dysfunction (EF <40%), pulmonary venous congestion, RV outflow obstruction, glibenclamide and cyclosporine therapy, coronary artery disease, systolic BP <85mmHg, renal impairment (serum creatinine >1.5mg/dL, those on other PAH treatments within a one month period of enrollment, anticoagulation therapy, planned surgical procedures during the study period and inability to perform the study protocol were excluded.

 

All patients received the full 48 weeks of treatment. The dose of inhaled iloprost was gradually uptitrated to the target dose of 2.5-5mcg divided by 6-9 times per day.  No adverse drug-related events occurred during the study period. Patients were assessed at baseline and at 48 weeks of therapy – various clinical, laboratory and echocardiographic measures were assessed. The mean age of the cohort was 44.2 years. All patients were WHO functional class III-IV at enrollment.

 

On echocardiography, the following parameters showed a significant improvement after therapy:

  • Reduction in mean pulmonary artery pressure (42.5 to 36.5mmHG, p=0.004)
  • Reduction in systolic pulmonary artery pressure (92.6 to 74.5mmHg, p=0.005)
  • Small improvement in RV fractional area change (36.4 to 44.4%, p=0.032)
  • Significant improvement in RV MPI (0.68 to 0.52, p<0.05)
  • Significant improvement in tricuspid annular peak systolic velocity (9.1 to 11.0, p<0.05)

May ACHD 4

May ACHD 5

 

Furthermore, as depicted in figure 1 above, both global and regional strain parameters were significantly improved.

 

These echocardiographic improvements in RV function and pulmonary pressure were accompanied by functional improvement on clinical grounds. The 6MWD (310.6 to 399.7m, p<0.001) and SaO2 (90.9 to 92.5 %, p=0.022) showed a significant improvement after the 48 weeks on iloprost.  There was a significant improvement in the WHO functional class of the cohort (mainly from class III to class II, p=0.006). NT-proBNP levels also improved significantly (802 to 687 ng/L, p=0.008).

 

 

 

The study may not be generalizable due to its small study sample and the lack of a placebo arm. These pulmonary vascular measures were derived from echo parameters, and these were not validated against the gold standard of cardiac catheterization in this population. Further larger studies are warranted to verify these results.

 

 

Mortality Risk Stratification in Fontan Patients Who Underwent Heart Transplantation.

Berg CJ, Bauer BS, Hageman A, Aboulhosn JA, Reardon LC.

Am J Cardiol. 2017 May 15;119(10):1675-1679. doi: 10.1016/j.amjcard.2017.02.005. Epub 2017 Mar 1.

PMID: 28341356

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Select item 28508439

 

 

Take Home Points:

 

  • Better risk stratification is needed for patient selection to improve post OHT outcomes for Fontan patients.
  • In this study, all-cause mortality in a Fontan population, including adults and children, was 44% after OHT during a mean follow-up time of 3.5 years (n=36)
  • All patients in this study who required pre-OHT renal replacement therapy or pre-OHT ECMO died post OHT, mostly in the immediate perioperative period.
  • Risk factors for post OHT mortality include: young age at time of OHT (<18 years), short interval between Fontan and OHT (<10 years), severe systolic dysfunction (EF < 20%), moderate or severe atrioventricular valve regurgitation, an elevated MELD-XI score > 19, pre-OHT renal replacement therapy, or pre-OHT ECMO.
  • The authors suggest a risk score of 0-12 points based on presence of risk factors. In their retrospective analysis, a score > 5 points was associated with 88% mortality; 2-5 points with 50% mortality, and 0-1 points with 0% mortality.

 

 

Kay_William_MD.16.CVaCommentary from Dr. W. Aaron Kay (Indianapolis), section editor of ACHD Journal Watch: 

The Fontan procedure, which has been the final common pathway for most single ventricle patients for well over 20 years now, has a number of drawbacks, and a significant number of patients will ultimately require orthotopic heart transplantation (OHT).  However, OHT is a scarce resource and federal guidelines are quite strict regarding organ allocation, and Fontan survivors, thought to be at higher risk of periprocedural complications, must compete against other heart failure patients, many of whom have never undergone prior open heart surgery.

 

This paper is a retrospective review of all patients (children and adults) with failing Fontan physiology who underwent transplantation from 1991 to 2014 at UCLA (n=36).  Average follow-up time was 3.5 years, with 44% patients having a postoperative mortality.  The authors evaluated potential risk factors for Fontan-OHT mortality and came up with a risk score that will need to be evaluated in newer multicenter, ideally prospective, studies.

 

Risk factors found to correlate with mortality including being <18 years old at time of OHT, a short interlude <10 years between Fontan and OHT, severe systolic dysfunction of single ventricle (EF < 20%), moderate or severe atrioventricular valve regurgitation, an elevated Model of End-stage Liver Disease eXcluding INR score (MELD-XI), need for renal replacement therapy, or need for advanced mechanical support prior to OHT.

 

All patients who required preoperative renal replacement therapy or ECMO died after OHT.  Interestingly, in this study, moderate or severe atrioventricular valve regurgitation was a stronger predictor of mortality than a severely depressed EF < 20%.  A MELD-XI score > 19 was correlated with increased odds of all-cause mortality after OHT.  Interestingly, there was no correlation between serum creatinine, bilirubin, or MELD-XI with documented presence of chronic kidney disease, cirrhosis, or ascites.  The authors note that there is evidence in the literature that patients with protein losing enteropathy (PLE) may have lower bilirubin due to wasting of the bilirubin in intestinal effluent, which may result in a falsely reassuring MELD-XI score.

 

A scoring scheme was composed by the authors including the 6 preoperative factors found to have elevated hazard ratios.  Risk factors were assigned 1,2, or 3 points based on HR <4, 4-6, or >6, respectively, with a maximum total score of 12.  No patient with a score of 0 or 1 points died post OHT during the follow-up period.  Patients with 2-5 points had 50% mortality, and patients with scores > 5 points had 88% mortality.

ACHD May 2017

 

  1. Increased risk of thromboembolic events in adult congenital heart disease patients with atrial tachyarrhythmias: Bias due to the data sparsity.

Ayubi E, Safiri S, Mansournia MA.

Int J Cardiol. 2017 Jul 15;239:20. doi: 10.1016/j.ijcard.2017.02.133. No abstract available.

PMID: 28560967

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  1. Cognitive dysfunction in adult CHD with different structural complexity.

Tyagi M, Fteropoulli T, Hurt CS, Hirani SP, Rixon L, Davies A, Picaut N, Kennedy F, Deanfield J, Cullen S, Newman SP.

Cardiol Young. 2017 Jul;27(5):851-859. doi: 10.1017/S1047951116001396. Epub 2016 Oct 18.

PMID: 27751192

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  1. Arterial stiffness and arterial function in adult cyanotic patients with congenital heart disease.

Trojnarska O, Szczepaniak-Chicheł L, Gabriel M, Bartczak-Rutkowska A, Rupa-Matysek J, Tykarski A, Grajek S.

J Cardiol. 2017 Jul;70(1):62-67. doi: 10.1016/j.jjcc.2016.09.003. Epub 2016 Oct 15.

PMID: 27756510

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Select item 27913750

 

  1. Cardiorespiratory Fitness, Not the Severity of the Condition, Dictates Late Outcomes After Fontan Procedures.

d’Udekem Y.

J Am Coll Cardiol. 2017 Jun 6;69(22):2745-2747. doi: 10.1016/j.jacc.2017.03.581. No abstract available.

PMID: 28571640

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Select item 28571639

 

  1. Longitudinal Outcomes of Patients With Single Ventricle After the Fontan Procedure.

Atz AM, Zak V, Mahony L, Uzark K, D’agincourt N, Goldberg DJ, Williams RV, Breitbart RE, Colan SD, Burns KM, Margossian R, Henderson HT, Korsin R, Marino BS, Daniels K, McCrindle BW; Pediatric Heart Network Investigators.

J Am Coll Cardiol. 2017 Jun 6;69(22):2735-2744. doi: 10.1016/j.jacc.2017.03.582.

PMID: 28571639

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Select item 28571637

 

  1. Knowledge-based reconstruction for measurement of right ventricular volumes on cardiovascular magnetic resonance images in a mixed population.

Pieterman ED, Budde RPJ, Robbers-Visser D, van Domburg RT, Helbing WA.

Congenit Heart Dis. 2017 Jun 5. doi: 10.1111/chd.12484. [Epub ahead of print]

PMID: 28580763

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Select item 28580760

 

  1. Mitral valve prolapse and Marfan syndrome.

Thacoor A.

Congenit Heart Dis. 2017 Jun 5. doi: 10.1111/chd.12467. [Epub ahead of print] Review.

PMID: 28580713

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  1. Long-term outcomes after aortic coarctation repair in Maltese patients: A population-based study.

Caruana M, Grech V.

Congenit Heart Dis. 2017 Jun 5. doi: 10.1111/chd.12488. [Epub ahead of print]

PMID: 28580660

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Select item 28580658

 

  1. Transition of Care in Congenital Heart Disease: Ensuring the Proper Handoff.

Lee A, Bailey B, Cullen-Dean G, Aiello S, Morin J, Oechslin E.

Curr Cardiol Rep. 2017 Jun;19(6):55. doi: 10.1007/s11886-017-0859-5. Review.

PMID: 28477319

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Select item 28432659

 

  1. Current Role of Blood and Urine Biomarkers in the Clinical Care of Adults with Congenital Heart Disease.

Rajpal S, Alshawabkeh L, Opotowsky AR.

Curr Cardiol Rep. 2017 Jun;19(6):50. doi: 10.1007/s11886-017-0860-z. Review.

PMID: 28432659

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Select item 28306681

 

  1. Anesthesia in adults with congenital heart disease.

Baehner T, Ellerkmann RK.

Curr Opin Anaesthesiol. 2017 Jun;30(3):418-425. doi: 10.1097/ACO.0000000000000468.

PMID: 28306681

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Select item 28407053

 

  1. EuroEcho-Imaging 2016: highlights.

Magne J, Popescu BA, Bucciarelli-Ducci C, Cosyns B, Donal E, Gimelli A, Miller O, Badano L, Habib G.

Eur Heart J Cardiovasc Imaging. 2017 Jun 1;18(6):621-628. doi: 10.1093/ehjci/jex063.

PMID: 28407053

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Select item 28329058

 

  1. Heart transplantation for adults with congenital heart disease: current status and future prospects.

Matsuda H, Ichikawa H, Ueno T, Sawa Y.

Gen Thorac Cardiovasc Surg. 2017 Jun;65(6):309-320. doi: 10.1007/s11748-017-0777-x. Epub 2017 Apr 24. Review.

PMID: 28439697

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Select item 27831545

 

  1. Aortopathies in adult congenital heart disease and genetic aortopathy syndromes: management strategies and indications for surgery.

Kuijpers JM, Mulder BJ.

Heart. 2017 Jun;103(12):952-966. doi: 10.1136/heartjnl-2015-308626. Epub 2017 Mar 7. No abstract available.

PMID: 28270426

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Select item 28259844

 

  1. Cyanotic congenital heart disease and atherosclerosis.

Tarp JB, Jensen AS, Engstrøm T, Holstein-Rathlou NH, Søndergaard L.

Heart. 2017 Jun;103(12):897-900. doi: 10.1136/heartjnl-2016-311012. Epub 2017 Mar 4. Review.

PMID: 28259844

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Select item 27993911

 

  1. The management of the third stage of labour in women with heart disease.

Cauldwell M, Steer PJ, Swan L, Uebing A, Gatzoulis MA, Johnson MR.

Heart. 2017 Jun;103(12):945-951. doi: 10.1136/heartjnl-2016-310607. Epub 2016 Dec 19.

PMID: 27993911

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Select item 28528723

 

  1. Echocardiography-Derived Left Ventricular Outflow Tract Gradient and Left Ventricular Posterior Wall Thickening Are Associated with Outcomes for Anatomic Repair in Congenitally Corrected Transposition of the Great Arteries.

Moodley S, Balasubramanian S, Tacy TA, Chan F, Hanley FL, Punn R.

J Am Soc Echocardiogr. 2017 Jun 1. pii: S0894-7317(17)30219-5. doi: 10.1016/j.echo.2017.03.019. [Epub ahead of print]

PMID: 28579248

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Select item 28391001

 

  1. Endothelin inhibitors lower pulmonary vascular resistance and improve functional capacity in patients with Fontan circulation.

Agnoletti G, Gala S, Ferroni F, Bordese R, Appendini L, Pace Napoleone C, Bergamasco L.

J Thorac Cardiovasc Surg. 2017 Jun;153(6):1468-1475. doi: 10.1016/j.jtcvs.2017.01.051. Epub 2017 Feb 10.

PMID: 28283234

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Select item 28268011

 

  1. Red Flags for Maltese Adults with Congenital Heart Disease: Poorer Dental Care and Less Sports Participation Compared to Other European Patients-An APPROACH-IS Substudy.

Caruana M, Apers S, Kovacs AH, Luyckx K, Thomet C, Budts W, Sluman M, Eriksen K, Dellborg M, Berghammer M, Johansson B, Soufi A, Callus E, Moons P, Grech V; APPROACH-IS consortium and the International Society for Adult Congenital Heart Disease (ISACHD).

Pediatr Cardiol. 2017 Jun;38(5):965-973. doi: 10.1007/s00246-017-1604-y. Epub 2017 Mar 24.

PMID: 28341902

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Select item 28210768

 

  1. The Lymphatic Circulation in Adaptations to the Fontan Circulation.

Menon S, Chennapragada M, Ugaki S, Sholler GF, Ayer J, Winlaw DS.

Pediatr Cardiol. 2017 Jun;38(5):886-892. doi: 10.1007/s00246-017-1576-y. Epub 2017 Feb 16. Review.

PMID: 28210768

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Select item 27816335

 

  1. A Rare Case of Anomalous Left Coronary Artery From the Pulmonary Artery (Bland-White-Garland Syndrome) in a 68-Year-Old Woman.

Roberts SM, Banbury T, Mehta A.

Semin Cardiothorac Vasc Anesth. 2017 Jun;21(2):186-190. doi: 10.1177/1089253216659146. Epub 2016 Jul 9.

PMID: 27401860

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Select item 27688032

 

  1. Outcomes of pulmonary arterial hypertension therapy in Australia: is monotherapy adequate?

Moonen A, Garsia R, Youssef P, Torzillo P, Corte T, Boehm C, Cordina R, Celermajer D, Lau E.

Intern Med J. 2017 May 31. doi: 10.1111/imj.13495. [Epub ahead of print]

PMID: 28560817

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Select item 28561998

 

  1. Imaging adult patients with Fontan circulation.

Ginde S, Goot BH, Frommelt PC.

Curr Opin Cardiol. 2017 May 25. doi: 10.1097/HCO.0000000000000422. [Epub ahead of print]

PMID: 28548989

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Select item 28576625

 

  1. Detection of mechanical complications related to the potential risk of sudden cardiac death in patients with pulmonary arterial hypertension by computed tomography.

Lee SE, Im JH, Sung JM, Cho IJ, Shim CY, Hong GR, Chung N, Jung JW, Chang HJ.

Int J Cardiol. 2017 May 25. pii: S0167-5273(17)31912-5. doi: 10.1016/j.ijcard.2017.05.090. [Epub ahead of print]

PMID: 28576625

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Select item 28549022

 

  1. Pictorial Review of Surgical Anatomy in Adult Congenital Heart Disease.

De Cecco CN, Muscogiuri G, Madrid Pérez JM, Eid M, Suranyi P, Lesslie VW, Bastarrika G.

J Thorac Imaging. 2017 May 25. doi: 10.1097/RTI.0000000000000273. [Epub ahead of print]

PMID: 28549022

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Select item 28540525

 

  1. Pregnancy-associated plasma protein-A (PAPP-A) and the proform of the eosinophil major basic protein (ProMBP) are associated with increased risk of death in heart failure patients.

Dembic M, Hedley PL, Torp-Pedersen C, Køber L, Christiansen M.

Scand J Clin Lab Invest. 2017 May 24:1-6. doi: 10.1080/00365513.2017.1325926. [Epub ahead of print]

PMID: 28537443

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Select item 28542047

 

  1. Inferior Vena Cava Thrombus in a Postpartum Patient With Fontan Physiology: A Case Report.

Tashjian JA, Fraint H, DiNardo J, Rouine-Rapp K.

A A Case Rep. 2017 May 23. doi: 10.1213/XAA.0000000000000548. [Epub ahead of print]

PMID: 28542047

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Select item 28580361

 

  1. Effect of phosphodiesterase-5 inhibition with Tadalafil on SystEmic Right VEntricular size and function – A multi-center, double-blind, randomized, placebo-controlled clinical trial – SERVE trial – Rational and design.

Tobler D, Bouchardy J, Reto E, Heg D, Müller C, Frenk A, Gabriel H, Schwitter J, Rutz T, Buechel RR, Willhelm M, Trachsel L, Freese M, Greutmann M, Schwerzmann M; SERVE trial.

Int J Cardiol. 2017 May 23. pii: S0167-5273(17)32122-8. doi: 10.1016/j.ijcard.2017.05.079. [Epub ahead of print]

PMID: 28566262

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Select item 28521893

 

  1. The use of Macitentan in Fontan circulation: a case report.

Demetriades P, Aziz A, Condliffe R, Bowater SE, Clift PF.

BMC Cardiovasc Disord. 2017 May 22;17(1):131. doi: 10.1186/s12872-017-0567-5.

PMID: 28532389 Free PMC Article

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Select item 28544787

 

  1. Preparing adolescents with heart problems for transition to adult care, 2009-2010 National Survey of Children with Special Health Care Needs.

Downing KF, Oster ME, Farr SL.

Congenit Heart Dis. 2017 May 19. doi: 10.1111/chd.12476. [Epub ahead of print]

PMID: 28523852

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Select item 28523732

 

  1. Transition in Patients with Congenital Heart Disease in Germany: Results of a Nationwide Patient Survey.

Helm PC, Kaemmerer H, Breithardt G, Sticker EJ, Keuchen R, Neidenbach R, Diller GP, Tutarel O, Bauer UMM.

Front Pediatr. 2017 May 19;5:115. doi: 10.3389/fped.2017.00115. eCollection 2017.

PMID: 28580351 Free Article

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Select item 28525297

 

  1. Elevated sympathetic activity, endothelial dysfunction, and late hypertension after repair of coarctation of the aorta.

Lee MGY, Hemmes RA, Mynard J, Lambert E, Head GA, Cheung MMH, Konstantinov IE, Brizard CP, Lambert G, d’Udekem Y.

Int J Cardiol. 2017 May 19. pii: S0167-5273(17)30820-3. doi: 10.1016/j.ijcard.2017.05.075. [Epub ahead of print]

PMID: 28545853

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Select item 28525615

 

  1. Gerbode defect and multivalvular dysfunction: Complex complications in adult congenital heart disease.

Ruivo C, Guardado J, Montenegro Sá F, Saraiva F, Antunes A, Correia J, Morais J.

Echocardiography. 2017 May 18. doi: 10.1111/echo.13561. [Epub ahead of print]

PMID: 28517030

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Select item 28522658

 

  1. Effect of Fontan geometry on exercise haemodynamics and its potential implications.

Tang E, Wei ZA, Whitehead KK, Khiabani RH, Restrepo M, Mirabella L, Bethel J, Paridon SM, Marino BS, Fogel MA, Yoganathan AP.

Heart. 2017 May 18. pii: heartjnl-2016-310855. doi: 10.1136/heartjnl-2016-310855. [Epub ahead of print]

PMID: 28522658

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Select item 28539208

 

  1. Impaired atrioventricular transport in patients with transposition of the great arteries palliated by atrial switch and preserved systolic right ventricular function: A magnetic resonance imaging study.

Ladouceur M, Kachenoura N, Soulat G, Bollache E, Redheuil A, Azizi M, Delclaux C, Chatellier G, Boutouyrie P, Iserin L, Bonnet D, Mousseaux E.

Congenit Heart Dis. 2017 May 16. doi: 10.1111/chd.12472. [Epub ahead of print]

PMID: 28508510

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Select item 28508990

 

  1. Adolescents with congenital heart disease: their opinions about the preparation for transfer to adult care.

Burström Å, Bratt EL, Frenckner B, Nisell M, Hanséus K, Rydberg A, Öjmyr-Joelsson M.

Eur J Pediatr. 2017 May 16. doi: 10.1007/s00431-017-2917-9. [Epub ahead of print]

PMID: 28508990

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Select item 28510647

 

  1. Lymphodynamics in Congenital HeartDisease: The Forgotten Circulation.

Kreutzer J, Kreutzer C.

J Am Coll Cardiol. 2017 May 16;69(19):2423-2427. doi: 10.1016/j.jacc.2017.03.559. No abstract available.

PMID: 28494979

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Select item 28494978

 

  1. National Trends and In-Hospital Outcomes in Pregnant Women With Heart Disease in the United States.

Lima FV, Yang J, Xu J, Stergiopoulos K.

Am J Cardiol. 2017 May 15;119(10):1694-1700. doi: 10.1016/j.amjcard.2017.02.003. Epub 2017 Feb 28.

PMID: 28343597

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Select item 28341356

 

  1. Mortality Risk Stratification in Fontan Patients Who Underwent Heart Transplantation.

Berg CJ, Bauer BS, Hageman A, Aboulhosn JA, Reardon LC.

Am J Cardiol. 2017 May 15;119(10):1675-1679. doi: 10.1016/j.amjcard.2017.02.005. Epub 2017 Mar 1.

PMID: 28341356

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Select item 28508439

 

  1. How often is congenital heart disease recognized as a significant comorbidity among hospitalized adults with congenital heart disease?

Robbins JM, Onukwube J, Goudie A, Collins RT 2nd.

Int J Cardiol. 2017 May 15;235:42-48. doi: 10.1016/j.ijcard.2017.02.100. Epub 2017 Feb 22.

PMID: 28279500

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Select item 28506276

 

  1. Original Findings and Updated Meta-Analysis for the Association Between Maternal Diabetes and Risk for Congenital Heart Disease Phenotypes.

Hoang TT, Marengo LK, Mitchell LE, Canfield MA, Agopian AJ.

Am J Epidemiol. 2017 May 13:1-11. doi: 10.1093/aje/kwx033. [Epub ahead of print]

PMID: 28505225

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Select item 28501797

 

  1. Predictors of procedural complications in adult Fontan patients undergoing non-cardiac procedures.

Egbe AC, Khan AR, Ammash NM, Barbara DW, Oliver WC, Said SM, Akintoye E, Warnes CA, Connolly HM.

Heart. 2017 May 13. pii: heartjnl-2016-311039. doi: 10.1136/heartjnl-2016-311039. [Epub ahead of print]

PMID: 28501797

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Select item 28511778

 

  1. [Congenital heart disease in adolescents and adults: Management in a general cardiology department in Senegal].

Mbaye A, Bodian M, Ngaïdé AA, Abdourafiq H, Leye MCBO, Savodogo S, Aw F, Ndiaye M, Kouamé I, Babaka K, Dioum M, Gaye ND, Sarr SA, Ndiaye MB, Kane AD, Kane A.

Ann Cardiol Angeiol (Paris). 2017 May 12. pii: S0003-3928(17)30020-3. doi: 10.1016/j.ancard.2017.02.003. [Epub ahead of print] French.

PMID: 28506578

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Select item 28498066

 

  1. Hospital Inpatient Costs for Single Ventricle Patients Surviving the Fontan Procedure.

Huang L, Schilling C, Dalziel KM, Xie S, Celermajer DS, McNeil JJ, Winlaw D, Hornung TS, Radford DJ, Grigg LE, Bullock A, Wheaton GR, Justo RN, Blake J, Bishop R, Du Plessis K, d’Udekem Y.

Am J Cardiol. 2017 May 11. pii: S0002-9149(17)30785-3. doi: 10.1016/j.amjcard.2017.04.049. [Epub ahead of print]

PMID: 28583678

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Select item 28493591

 

  1. Congenital Heart Disease and High Altitude: Is Chronic Hypoxia a Common Factor in Intellectual Impairment?

Ghimire LV.

High Alt Med Biol. 2017 May 9. doi: 10.1089/ham.2017.0043. [Epub ahead of print] No abstract available.

PMID: 28485995

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Select item 28485227

 

  1. Predicting long-term mortality after Fontan procedures: A risk score based on 6707 patients from 28 studies.

Alsaied T, Bokma JP, Engel ME, Kuijpers JM, Hanke SP, Zuhlke L, Zhang B, Veldtman GR.

Congenit Heart Dis. 2017 May 8. doi: 10.1111/chd.12468. [Epub ahead of print]

PMID: 28480627

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Select item 28534022

 

  1. Mental Health Problems in Parents of Children with Congenital Heart Disease.

Kolaitis GA, Meentken MG, Utens EMWJ.

Front Pediatr. 2017 May 8;5:102. doi: 10.3389/fped.2017.00102. eCollection 2017. Review.

PMID: 28534022 Free PMC Article

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Select item 28486386

 

  1. Extracardiac Conduit Fontan – Outcome Data in Early Adulthood.

Zentner D, Cheshire C, Grigg L.

Heart Lung Circ. 2017 May 3. pii: S1443-9506(17)30332-3. doi: 10.1016/j.hlc.2017.03.162. [Epub ahead of print]

PMID: 28545820

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Select item 28469241

 

  1. Forced vital capacity predicts morbidity and mortality in adults with repaired tetralogy of Fallot.

Cohen KE, Buelow MW, Dixon J, Brazauskas R, Cohen SB, Earing MG, Ginde S.

Congenit Heart Dis. 2017 May 2. doi: 10.1111/chd.12470. [Epub ahead of print]

PMID: 28464509

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Select item 28472306

 

  1. Managing subfertility in patients with heart disease: What are the choices?

Cauldwell M, Patel RR, Steer PJ, Swan L, Norman-Taylor J, Gatzoulis M, Johnson MR.

Am Heart J. 2017 May;187:29-36. doi: 10.1016/j.ahj.2017.02.007. Epub 2017 Feb 15. Review.

PMID: 28454805

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Select item 28454797

 

  1. Noninvasive Screening for Pulmonary Hypertension by Exercise Testing in Congenital Heart Disease.

Müller J, Heck PB, Ewert P, Hager A.

Ann Thorac Surg. 2017 May;103(5):1544-1549. doi: 10.1016/j.athoracsur.2016.09.038. Epub 2016 Dec 1.

PMID: 27914635

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Select item 27878830

 

  1. An adult case of Kommerell’s diverticulum with a right-sided aortic arch.

Tsutsumi K, Nishida K, Tsukamoto J, Iijima N, Ishida O.

Asian Cardiovasc Thorac Ann. 2017 May;25(4):307-309. doi: 10.1177/0218492317707146. Epub 2017 Apr 29.

PMID: 28457170

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Select item 28510741

 

  1. A congenital diverticulum of the left ventricular apex manifested by stroke and recurrent ventricular tachycardia.

Dostálová G, Paleček T, Kuchynka P, Havránek Š, Mašek M, Hlubocká Z, Karetová D, Wichterle D, Dušková J, Lindner J, Linhart A.

Cardiovasc Pathol. 2017 May – Jun;28:3-6. doi: 10.1016/j.carpath.2017.01.009. Epub 2017 Feb 4.

PMID: 28219755

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Select item 28488412

 

  1. Congenital Heart Disease: Multimodal Imaging Is Every Day’s Routine.

Beerbaum PBJ.

Circ Cardiovasc Imaging. 2017 May;10(5). pii: e006589. doi: 10.1161/CIRCIMAGING.117.006589. No abstract available.

PMID: 28495825

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Select item 28495824

 

  1. How to Image the Dilated Right Ventricle.

Partington SL, Kilner PJ.

Circ Cardiovasc Imaging. 2017 May;10(5). pii: e004688. doi: 10.1161/CIRCIMAGING.116.004688. Review. No abstract available.

PMID: 28495824

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Select item 28495823

 

  1. How to Image the Adult Patient With Fontan Circulation.

Hauser JA, Taylor AM, Pandya B.

Circ Cardiovasc Imaging. 2017 May;10(5). pii: e004273. doi: 10.1161/CIRCIMAGING.116.004273. Review. No abstract available.

PMID: 28495823

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Select item 28495821

 

  1. How to Image Repaired Tetralogy of Fallot.

Valente AM, Geva T.

Circ Cardiovasc Imaging. 2017 May;10(5). pii: e004270. doi: 10.1161/CIRCIMAGING.116.004270. Review. No abstract available.

PMID: 28495821

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Select item 27659940

 

  1. Improving the quality of transition and transfer of care in young adults with congenital heart disease.

Everitt IK, Gerardin JF, Rodriguez FH 3rd, Book WM.

Congenit Heart Dis. 2017 May;12(3):242-250. doi: 10.1111/chd.12463. Review.

PMID: 28580608

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Select item 28371362

 

  1. Pregnancy-related acute aortic dissection in Marfan syndrome: A review of the literature.

Smith K, Gros B.

Congenit Heart Dis. 2017 May;12(3):251-260. doi: 10.1111/chd.12465. Epub 2017 Apr 2. Review.

PMID: 28371362

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Select item 28244680

 

  1. Correlates of posttraumatic stress disorder in adults with congenital heart disease.

Eslami B.

Congenit Heart Dis. 2017 May;12(3):357-363. doi: 10.1111/chd.12452. Epub 2017 Feb 20.

PMID: 28217850

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Select item 28211263

 

  1. Residents’ understanding of adult congenital heart disease.

Cooper P, Hindes M, Maul TM, Cook SC.

Congenit Heart Dis. 2017 May;12(3):309-314. doi: 10.1111/chd.12441. Epub 2017 Jan 16.

PMID: 28092429

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Select item 27893194

 

  1. A first population-based long-term outcome study in adults with repaired tetralogy of Fallot in Malta.

Caruana M, Grech V.

Congenit Heart Dis. 2017 May;12(3):301-308. doi: 10.1111/chd.12439. Epub 2016 Nov 28.

PMID: 27893189

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Select item 27885832

 

  1. The power in being together for young adults who have heart disease – the photoshoot experience.

Gallagher R, Potter E, Thomson Mangnall L, Ladak L, Gallagher P, Neubeck L.

Heart Lung. 2017 May – Jun;46(3):199-204. doi: 10.1016/j.hrtlng.2017.02.004. Epub 2017 Mar 31.

PMID: 28366291

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Select item 28237272

 

  1. Maternal Antihypertensive Medication Use and Congenital Heart Defects: Updated Results From the National Birth Defects Prevention Study.

Fisher SC, Van Zutphen AR, Werler MM, Lin AE, Romitti PA, Druschel CM, Browne ML; and the National Birth Defects Prevention Study.

Hypertension. 2017 May;69(5):798-805. doi: 10.1161/HYPERTENSIONAHA.116.08773. Epub 2017 Apr 3.

PMID: 28373593

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Select item 28584431

 

  1. Effect of maternal age and cardiac disease severity on outcome of pregnancy in women with congenital heart disease.

Furenäs E, Eriksson P, Wennerholm UB, Dellborg M.

Int J Cardiol. 2017 May 1. pii: S0167-5273(17)30391-1. doi: 10.1016/j.ijcard.2017.04.100. [Epub ahead of print]

PMID: 28539207

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Select item 28238509

 

  1. Preconception counseling, predicting risk and outcomes in women with mWHO 3 and 4 heart disease.

Cauldwell M, Ghonim S, Uebing A, Swan L, Steer PJ, Gatzoulis M, Johnson MR.

Int J Cardiol. 2017 May 1;234:76-80. doi: 10.1016/j.ijcard.2017.02.003. Epub 2017 Feb 4.

PMID: 28238509

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Select item 28209388

 

  1. ACR Appropriateness Criteria<sup>®</sup> Known or Suspected Congenital Heart Disease in the Adult.

Expert Panel on Cardiac Imaging:, Woodard PK, Ho VB, Akers SR, Beache G, Brown RKJ, Cummings KW, Greenberg SB, Min JK, Stillman AE, Stojanovska J, Jacobs JE.

J Am Coll Radiol. 2017 May;14(5S):S166-S176. doi: 10.1016/j.jacr.2017.02.036.

PMID: 28473073

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Select item 27492657

 

  1. Effects of long-term iloprost treatment on right ventricular function in patients with Eisenmenger syndrome.

Chon MK, Cho KI, Cha KS, Seo JS, Kim DS.

J Cardiol. 2017 May;69(5):741-746. doi: 10.1016/j.jjcc.2016.07.002. Epub 2016 Aug 1.

PMID: 27492657

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Select item 28245348

 

  1. Isolated Aneurysms of the Membranous Ventricular Septum Without Residual Shunts: Systematic Review and Description of 3 Cases in Adults.

Abdul Jabbar A, Mufti O, Mazur W, Quraishi MB, Srivastava BK, Tivakaran V.

J Ultrasound Med. 2017 May;36(5):869-878. doi: 10.7863/ultra.16.02087. Epub 2017 Feb 23. Review.

PMID: 28230264

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Select item 28370380

 

  1. Clinical Characteristics of Adult Dogs More Than 5 Years of Age at Presentation for Patent Ductus Arteriosus.

Boutet BG, Saunders AB, Gordon SG.

J Vet Intern Med. 2017 May;31(3):685-690. doi: 10.1111/jvim.14689. Epub 2017 Apr 3.

PMID: 28370380 Free PMC Article

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Select item 28316101

 

  1. Myocardial cytochrome oxidase activity increases with age and hypoxemia in patients with congenital heart disease.

Onwugbufor M, Levy RJ, Zurakowski D, Jonas RA, Sinha P.

Perfusion. 2017 May;32(4):306-312. doi: 10.1177/0267659116681435. Epub 2016 Dec 5.

PMID: 27913766 Free PMC Article

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Select item 28434627

 

  1. [Adult congenital heart disease: Medical and psychosocial issues].

Ladouceur M, Pontnau F, Iserin L.

Presse Med. 2017 May;46(5):523-529. doi: 10.1016/j.lpm.2017.02.003. Epub 2017 Mar 14. French.

PMID: 28314442

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Select item 28126509

 

  1. [Cardiac rehabilitation for children and adults with congenital heart disease].

Amedro P, Gavotto A, Bredy C, Guillaumont S.

Presse Med. 2017 May;46(5):530-537. doi: 10.1016/j.lpm.2016.12.001. Epub 2017 Jan 23. French.

PMID: 28126509

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Select item 28063755

 

  1. Real-world, long-term survival of incident patients with pulmonary arterial hypertension.

Marques-Alves P, Baptista R, Marinho da Silva A, Pêgo M, Castro G.

Rev Port Pneumol (2006). 2017 May – Jun;23(3):124-131. doi: 10.1016/j.rppnen.2017.01.006. Epub 2017 Mar 7.

PMID: 28283462 Free Article

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Select item 28549395

 

  1. Diagnostic value of Doppler echocardiography for identifying hemodynamic significant pulmonary valve regurgitation in tetralogy of Fallot: comparison with cardiac MRI.

Beurskens NEG, Gorter TM, Pieper PG, Hoendermis ES, Bartelds B, Ebels T, Berger RMF, Willems TP, van Melle JP.

Int J Cardiovasc Imaging. 2017 May 31. doi: 10.1007/s10554-017-1165-4. [Epub ahead of print]

PMID: 28567705

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Select item 28557290

 

  1. Right ventricular-vascular coupling in heart failure with preserved ejection fraction and pre- vs. post-capillary pulmonary hypertension.

Gorter TM, van Veldhuisen DJ, Voors AA, Hummel YM, Lam CSP, Berger RMF, van Melle JP, Hoendermis ES.

Eur Heart J Cardiovasc Imaging. 2017 May 22. doi: 10.1093/ehjci/jex133. [Epub ahead of print]

PMID: 28531295

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Select item 28533305

 

  1. Imaging the adult with transposition of the great arteries.

Anderson JH, Cetta F.

Curr Opin Cardiol. 2017 May 19. doi: 10.1097/HCO.0000000000000420. [Epub ahead of print]

PMID: 28537999

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Select item 28525585

 

  1. Frequency of Development of Aortic Valve Disease in Unrepaired Perimembranous Ventricular Septal Defects.

Padiyath A, Makil ES, Braley KT, Bolin EH, Tang X, Gossett JM, Collins RT 2nd.

Am J Cardiol. 2017 May 15;119(10):1670-1674. doi: 10.1016/j.amjcard.2017.02.004. Epub 2017 Feb 28.

PMID: 28325571

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Select item 28502268

 

  1. Cardiopulmonary exercise test in adults with prior Fontan operation: The prognostic value of serial testing.

Egbe AC, Driscoll DJ, Khan AR, Said SS, Akintoye E, Berganza FM, Connolly HM.

Int J Cardiol. 2017 May 15;235:6-10. doi: 10.1016/j.ijcard.2017.02.140. Epub 2017 Feb 28.

PMID: 28284501

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Select item 28576400

 

  1. [Congenital heart disease in adolescents and adults: Management in a general cardiology department in Senegal].

Mbaye A, Bodian M, Ngaïdé AA, Abdourafiq H, Leye MCBO, Savodogo S, Aw F, Ndiaye M, Kouamé I, Babaka K, Dioum M, Gaye ND, Sarr SA, Ndiaye MB, Kane AD, Kane A.

Ann Cardiol Angeiol (Paris). 2017 May 12. pii: S0003-3928(17)30020-3. doi: 10.1016/j.ancard.2017.02.003. [Epub ahead of print] French.

PMID: 28506578

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Select item 28509675

 

  1. Renal resistive index reflects Fontan pathophysiology and predicts mortality.

Ohuchi H, Negishi J, Hayama Y, Miyazaki A, Shiraishi I, Ichikawa H.

Heart. 2017 May 2. pii: heartjnl-2016-310812. doi: 10.1136/heartjnl-2016-310812. [Epub ahead of print]

PMID: 28465331

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Select item 28472305

 

  1. Anomalous origin of right coronary artery causing myocardial ischemia in a young patient.

Singhi AK, Bari EA, Banerjee S.

Ann Pediatr Cardiol. 2017 May-Aug;10(2):212-214. doi: 10.4103/apc.APC_151_16.

PMID: 28566835 Free PMC Article

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Select item 28566834

 

  1. Adult CHD: the ongoing need for physician counselling about heredity and contraceptive options.

Londono-Obregon C, Goldmuntz E, Davey BT, Zhang X, Slap GB, Kim YY.

Cardiol Young. 2017 May;27(4):671-676. doi: 10.1017/S1047951116001013. Epub 2016 Jul 7.

PMID: 27383541

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Select item 27373527

 

  1. Improving the quality of transition and transfer of care in young adults with congenital heart disease.

Everitt IK, Gerardin JF, Rodriguez FH 3rd, Book WM.

Congenit Heart Dis. 2017 May;12(3):242-250. doi: 10.1111/chd.12463. Review.

PMID: 28580608

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Select item 28244680

 

 

Pediatric Cardiology Featured Articles of May 2017

 

Pediatric Cardiology Reviews of May 2017 Manuscripts

 

Psychiatric Disorders and Function in Adolescents with Tetralogy of Fallot.

Holland JE, Cassidy AR, Stopp C, White MT, Bellinger DC, Rivkin MJ, Newburger JW, DeMaso DR.

J Pediatr. 2017 May 19. pii: S0022-3476(17)30595-4. doi: 10.1016/j.jpeds.2017.04.048. [Epub ahead of print]

PMID: 28533034

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Select item 28516823

 

Take Home Points:

 

  • Tetralogy of Fallot (TOF) is one of the common forms of critical congenital heart disease with excellent long-term survival.
  • Adolescents with TOF and associated genetic diagnosis showed an increased prevalence of anxiety disorder (43%) and lower global psychosocial function compared to adolescents with TOF without genetic diagnosis and normal population.
  • Adolescents with TOF without and with a genetic diagnosis had a higher lifetime prevalence of attention deficit hyperactivity disorder (ADHD) compared to normal population.
  • Adolescents with TOF especially those with genetic disorders are at high risk for psychiatric disorder and dysfunction and need screening and surveillance for these abnormalities.

 

Shaji Menon Portrait 12.15.14Commentary from Dr. Shaji Menon (Salt Lake City), section editor of Pediatric Cardiology Journal Watch: In the single center cross-sectional study from Boston Children’s Hospital 91 TOF patients between the ages of 13-16 years and 87 healthy controls completed a clinician-rated structured psychiatric interview, parent-/self-report measures of psychopathology, and brain magnetic resonance imaging.  Patients with TOF and degenerative diagnosis had a high prevalence of anxiety disorder (43%) and lower global psychosocial functioning score (median, 70; IQR, 63-75) compared to adolescence with TOF with our genetic diagnosis (15% and 83; IQR, 79-87, respectively; P = .04 and <.001, respectively) and control subjects (6% and 85; IQR, 76-90, respectively; P = .001 and <.001, respectively). TOF patients with and without associated genetic disorders had a higher lifetime prevalence of attention deficit hyperactivity disorder then the control population (19% and 39%, respectively, vs 5%; P = .04 and .002, respectively). Risk factors for anxiety, ADHD, and lower psychosocial functioning included older age, male sex, and low IQ. Medical variables were not predictive of psychiatric outcomes.

 

May peds 1

May peds 2

 

 

Neuro-developmental outcome in single-ventricle patients: is the Norwood procedure a risk factor?

Rotermann I, Logoteta J, Falta J, Wegner P, Jung O, Dütschke P, Scheewe J, Kramer HH, Hansen JH.

Eur J Cardiothorac Surg. 2017 May 2. doi: 10.1093/ejcts/ezx119. [Epub ahead of print]

PMID: 28472306

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Select item 28472474

 

Take Home Points:

 

  • Complex open heart surgeries like Norwood procedure in neonatal period is considered a risk factor for adverse neurodevelopmental outcomes.
  • In this study, neurodevelopmental outcome of preschool Fontan patients was in the normal range.
  • Surprisingly Norwood procedure was not a risk factor for neurodevelopmental impairment. Preoperative and patient specific factors were important determinants of neurodevelopmental outcome.

 

Commentary from Dr. Shaji Menon (Salt Lake City), section editor of Pediatric Cardiology Journal Watch: This study included Fontan patients between 3.5-7 years of age who underwent a Norwood procedure for hypoplastic left heart syndrome or other variants and children with other types of single ventricle anatomy not requiring cardiopulmonary pulmonary bypass in the neonatal period (95 patients; Norwood: n = 69; non-Norwood: n = 26). Verbal, performance and full-scale intelligence quotient (IQ) were evaluated with the Wechsler Preschool and Primary Scale of Intelligence. Cognitive functions were assessed with the German ‘Kognitiver Entwicklungstest fu¨r das Kindergartenalter’ (KET-KID).  On comparing Norwood subject to non-Norwood subjects there was no difference in verbal IQ: 98 (86–105) vs 93 (85–102), P = 0.312; performance IQ: 91 (86–100) vs 96 (86–100), P = 0.932; full-scale IQ: 93(86–101) vs 89 (84–98), P = 0.314; KET-KID non-verbal: 33 (18–62) vs 45 (15–54), P = 0.771; KET-KID global: 42 (14–65) vs 28 (6–63), P = 0.208).  Overall IQ was below 85.720% of Norwood and 35% of non-Norwood cases (p=0.18).  Preoperative factors like small head circumference Z score and complications before neonatal surgery were associated with lower scores.

May peds 3

May peds 4May peds 5May peds 6

 

Pediatric cardiology May 2017

 

  1. Cardiac haemangioma associated with a duct-dependent congenital heart disease in a newborn infant.

Djordjevic SA, Glumac S, Kalanj J.

Cardiol Young. 2017 Jul;27(5):990-992. doi: 10.1017/S1047951116002699. Epub 2017 Jan 12.

PMID: 28077189

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Select item 27751196

 

  1. Anatomical considerations for the management of a left-sided superior caval vein draining to the roof of the left atrium.

Saundankar J, Ho AB, Salmon AP, Anderson RH, Magee AG.

Cardiol Young. 2017 Jul;27(5):846-850. doi: 10.1017/S1047951116001384. Epub 2016 Sep 29.

PMID: 27680401

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Select item 26577068

 

  1. An interactive tool for rapid biventricular analysis of congenital heart disease.

Gilbert K, Lam HI, Pontré B, Cowan BR, Occleshaw CJ, Liu JY, Young AA.

Clin Physiol Funct Imaging. 2017 Jul;37(4):413-420. doi: 10.1111/cpf.12319. Epub 2015 Nov 17.

PMID: 26577068

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Select item 27756510

 

  1. Stress echocardiography: An overview for use in pediatric and congenital cardiology.

Ermis P.

Congenit Heart Dis. 2017 Jun 5. doi: 10.1111/chd.12495. [Epub ahead of print]

PMID: 28580760

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Select item 28580730

 

  1. Right aortic arch with situs solitus frequently heralds a vascular ring.

Evans WN, Acherman RJ, Ciccolo ML, Carrillo SA, Mayman GA, Luna CF, Rollins RC, Castillo WJ, Galindo A, Rothman A, Alexander JA, Kwan TW, Restrepo H.

Congenit Heart Dis. 2017 Jun 5. doi: 10.1111/chd.12487. [Epub ahead of print]

PMID: 28580730

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Select item 28580713

 

  1. Kawasaki disease: State of the art.

Newburger JW.

Congenit Heart Dis. 2017 Jun 5. doi: 10.1111/chd.12498. [Epub ahead of print]

PMID: 28580712

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Select item 28580660

 

  1. Kawasaki disease: Medical therapies.

Newburger JW.

Congenit Heart Dis. 2017 Jun 5. doi: 10.1111/chd.12502. [Epub ahead of print]

PMID: 28580631

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Select item 28582432

 

  1. In vivo efficacy of the AKT inhibitor ARQ 092 in Noonan Syndrome with multiple lentigines-associated hypertrophic cardiomyopathy.

Wang J, Chandrasekhar V, Abbadessa G, Yu Y, Schwartz B, Kontaridis MI.

PLoS One. 2017 Jun 5;12(6):e0178905. doi: 10.1371/journal.pone.0178905. eCollection 2017.

PMID: 28582432 Free Article

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Select item 28586709

 

  1. The motor repertoire in 3- to 5-month old infants with Down syndrome.

Herrero D, Einspieler C, Panvequio Aizawa CY, Mutlu A, Yang H, Nogolová A, Pansy J, Nielsen-Saines K, Marschik PB; GenGM Study Group.

Res Dev Disabil. 2017 Jun 3;67:1-8. doi: 10.1016/j.ridd.2017.05.006. [Epub ahead of print]

PMID: 28586709

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Select item 28583401

 

10.[Genetics of congenital heart diseases].

Bonnet D.

Presse Med. 2017 Jun 2. pii: S0755-4982(17)30252-X. doi: 10.1016/j.lpm.2017.05.014. [Epub ahead of print] French.

PMID: 28583745

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Select item 28583744

 

  1. Pulse oximetry is a feasible method for detecting neonatal critical congenital heart disease.

Hu XJ, Huang GY.

Acta Paediatr. 2017 Jun;106(6):1008. doi: 10.1111/apa.13801. Epub 2017 Mar 21. No abstract available.

PMID: 28235129

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Select item 28075515

 

  1. The limitations of pulse oximetry for critical congenital heart disease screening in the neonatal intensive care units.

Fernandes N, Lakshminrusimha S.

Acta Paediatr. 2017 Jun;106(6):1007. doi: 10.1111/apa.13742. Epub 2017 Jan 30. No abstract available.

PMID: 28075515

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Select item 28577664

 

  1. Feasibility of exercise stress echocardiography and myocardial response in patients with repaired congenital heart disease.

Hasan BS, Lunze FI, Alvi N, Shafer KM, Rhodes J.

Am Heart J. 2017 Jun;188:1-10. doi: 10.1016/j.ahj.2017.02.029. Epub 2017 Feb 23.

PMID: 28577664

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Select item 28161345

 

  1. Interruption of the Aortic Arch.

Combes N, Waldmann V, Heitz F, Bruguiere E, Quedreux JF, Vahdat O, Chambran P, Narayanan K, Marijon E.

Am J Med. 2017 Jun;130(6):e251-e252. doi: 10.1016/j.amjmed.2016.12.041. Epub 2017 Feb 2. No abstract available.

PMID: 28161345

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Select item 28425218

 

  1. Recurrence of congenital heart defects among siblings-a nationwide study.

Brodwall K, Greve G, Leirgul E, Tell GS, Vollset SE, Øyen N.

Am J Med Genet A. 2017 Jun;173(6):1575-1585. doi: 10.1002/ajmg.a.38237. Epub 2017 Apr 19.

PMID: 28425218

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Select item 28422456

 

  1. Long-Term Outcomes of Children With Trisomy 13 and 18 After Congenital Heart Disease Interventions.

Peterson JK, Kochilas LK, Catton KG, Moller JH, Setty SP.

Ann Thorac Surg. 2017 Jun;103(6):1941-1949. doi: 10.1016/j.athoracsur.2017.02.068. Epub 2017 Apr 26.

PMID: 28456396

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Select item 28223051

 

  1. [Mosaic trisomy 18. Series of cases].

Cammarata-Scalisi F, Lacruz-Rengel MA, Araque D, Da Silva G, Avendaño A, Callea M, Stock F, Guerrero Y, Aguilar E, Lacruz MJ, Sulbaran J.

Arch Argent Pediatr. 2017 Jun 1;115(3):e183-e186. doi: http://dx.doi.org/10.5546/aap.2017.e183. Spanish.

PMID: 28504507 Free Article

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Select item 28504505

 

  1. Retinovascular findings in newborns with critical congenital heart disease: A case series.

Fettah N, Kabatas EU, Doğan V, Zenciroğlu AL, Dilli D, Özyazıcı E, Koç M, Beken S, Dursun A, Kandemir S.

Arch Argent Pediatr. 2017 Jun 1;115(3):e175-e178. doi: http://dx.doi.org/10.5546/aap.2017.eng.e175. Spanish, English.

PMID: 28504505 Free Article

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Select item 28536187

 

  1. Ethnic and socioeconomic variation in incidence of congenital heart defects.

Knowles RL, Ridout D, Crowe S, Bull C, Wray J, Tregay J, Franklin RC, Barron DJ, Cunningham D, Parslow RC, Brown KL.

Arch Dis Child. 2017 Jun;102(6):496-502. doi: 10.1136/archdischild-2016-311143. Epub 2016 Dec 16.

PMID: 27986699 Free Article

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Select item 27530240

 

  1. Newborn pulse oximetry screening in practice.

Ismail AQT, Cawsey M, Ewer AK.

Arch Dis Child Educ Pract Ed. 2017 Jun;102(3):155-161. doi: 10.1136/archdischild-2016-311047. Epub 2016 Aug 16.

PMID: 27530240

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Select item 28544650

 

  1. Cost of Congenital Heart Disease Hospitalizations in Canada: A Population-Based Study.

Mackie AS, Tran DT, Marelli AJ, Kaul P.

Can J Cardiol. 2017 Jun;33(6):792-798. doi: 10.1016/j.cjca.2017.01.024. Epub 2017 Feb 10.

PMID: 28457736

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Select item 28347581

 

  1. Validity of Commercial Activity Trackers in Children With Congenital Heart Disease.

Voss C, Gardner RF, Dean PH, Harris KC.

Can J Cardiol. 2017 Jun;33(6):799-805. doi: 10.1016/j.cjca.2016.11.024. Epub 2016 Dec 18.

PMID: 28347581

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Select item 28457248

 

  1. Ebstein Anomaly.

Sherwin ED, Abrams DJ.

Card Electrophysiol Clin. 2017 Jun;9(2):245-254. doi: 10.1016/j.ccep.2017.02.007. Review.

PMID: 28457239

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Select item 28457237

 

  1. Use of Clinical Exome Sequencing in Isolated Congenital Heart Disease.

Zahavich L, Bowdin S, Mital S.

Circ Cardiovasc Genet. 2017 Jun;10(3). pii: e001581. doi: 10.1161/CIRCGENETICS.116.001581. No abstract available.

PMID: 28473349

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Select item 28468791

 

  1. Genetics of Congenital Heart Disease: Is the Glass Now Half-Full?

Leatherbury L, Berul CI.

Circ Cardiovasc Genet. 2017 Jun;10(3):e001746. doi: 10.1161/CIRCGENETICS.117.001746. No abstract available.

PMID: 28468791

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Select item 28559421

 

  1. Prospective ECG-triggering cardiac CT for infants with complex congenital heart disease using low-dose contrast medium, low tube voltage, and adaptive statistical iterative reconstruction.

Wang SY, Gao W, Zhong YM, Sun AM, Wang Q, Hu LW, Qiu HS, Li JY.

Clin Radiol. 2017 Jun;72(6):502-507. doi: 10.1016/j.crad.2017.01.017. Epub 2017 Mar 6.

PMID: 28267987

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Select item 28460704

 

  1. Effect of Fontan operation on liver stiffness in children with single ventricle physiology.

DiPaola FW, Schumacher KR, Goldberg CS, Friedland-Little J, Parameswaran A, Dillman JR.

Eur Radiol. 2017 Jun;27(6):2434-2442. doi: 10.1007/s00330-016-4614-x. Epub 2016 Oct 17.

PMID: 27752831

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Select item 28532240

 

  1. Incidence and Outcome of Acute Cardiorenal Syndrome in Hospitalized Children.

Athwani V, Bhargava M, Chanchlani R, Mehta AJ.

Indian J Pediatr. 2017 Jun;84(6):420-424. doi: 10.1007/s12098-017-2307-3. Epub 2017 Feb 27.

PMID: 28239760

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Select item 28132780

 

  1. Three-Dimensional Mitral Valve Morphology and Age-Related Trends in Children and Young Adults with Structurally Normal Hearts Using Transthoracic Echocardiography.

Jolley MA, Ghelani SJ, Adar A, Harrild DM.

J Am Soc Echocardiogr. 2017 Jun;30(6):561-571. doi: 10.1016/j.echo.2017.01.018. Epub 2017 Apr 6.

PMID: 28391001

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Select item 28497553

 

  1. Regression equations for calculation of z scores for echocardiographic measurements of right heart structures in healthy Han Chinese children.

Wang SS, Zhang YQ, Chen SB, Huang GY, Zhang HY, Zhang ZF, Wu LP, Hong WJ, Shen R, Liu YQ, Zhu JX.

J Clin Ultrasound. 2017 Jun;45(5):293-303. doi: 10.1002/jcu.22436. Epub 2017 Jan 25.

PMID: 28121016

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Select item 28230599

 

  1. Teaching congenital heart disease: A new era?

Beckerman Z, Mery CM.

J Thorac Cardiovasc Surg. 2017 Jun;153(6):1541. doi: 10.1016/j.jtcvs.2017.02.045. Epub 2017 Mar 9. No abstract available.

PMID: 28359576

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Select item 28314534

 

  1. Critical Congenital Heart Disease Newborn Screening Implementation: Lessons Learned.

McClain MR, Hokanson JS, Grazel R, Van Naarden Braun K, Garg LF, Morris MR, Moline K, Urquhart K, Nance A, Randall H, Sontag MK.

Matern Child Health J. 2017 Jun;21(6):1240-1249. doi: 10.1007/s10995-017-2273-4.

PMID: 28092064

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Select item 28393221

 

  1. Chromosome 13q deletion syndrome involving 13q31‑qter: A case report.

Wang YP, Wang DJ, Niu ZB, Cui WT.

Mol Med Rep. 2017 Jun;15(6):3658-3664. doi: 10.3892/mmr.2017.6425. Epub 2017 Apr 3.

PMID: 28393221 Free PMC Article

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Select item 28393185

 

  1. Impaired Pulmonary Function is an Additional Potential Mechanism for the Reduction of Functional Capacity in Clinically Stable Fontan Patients.

Turquetto ALR, Canêo LF, Agostinho DR, Oliveira PA, Lopes MICS, Trevizan PF, Fernandes FLA, Binotto MA, Liberato G, Tavares GMP, Neirotti RA, Jatene MB.

Pediatr Cardiol. 2017 Jun;38(5):981-990. doi: 10.1007/s00246-017-1606-9. Epub 2017 May 12.

PMID: 28500413

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Select item 28456828

 

  1. MicroRNAs Association in the Cardiac Hypertrophy Secondary to Complex Congenital Heart Disease in Children.

Sánchez-Gómez MC, García-Mejía KA, Pérez-Díaz Conti M, Díaz-Rosas G, Palma-Lara I, Sánchez-Urbina R, Klünder-Klünder M, Botello-Flores JA, Balderrábano-Saucedo NA, Contreras-Ramos A.

Pediatr Cardiol. 2017 Jun;38(5):991-1003. doi: 10.1007/s00246-017-1607-8. Epub 2017 Apr 5.

PMID: 28382463

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Select item 28374048

 

  1. Trends in National Institutes of Health-Funded Congenital Heart Disease Research from 2005 to 2015.

Burns KM, Pemberton VL, Schramm CA, Pearson GD, Kaltman JR.

Pediatr Cardiol. 2017 Jun;38(5):974-980. doi: 10.1007/s00246-017-1605-x. Epub 2017 Mar 27.

PMID: 28349207

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Select item 28341902

 

  1. The Prevalence of Congenital Heart Disease in Nonsyndromic Cleft Lip and/or Palate: A Systematic Review of the Literature.

Munabi NCO, Swanson J, Auslander A, Sanchez-Lara PA, Davidson Ward SL, Magee WP 3rd.

Ann Plast Surg. 2017 May 31. doi: 10.1097/SAP.0000000000001069. [Epub ahead of print]

PMID: 28570447

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Select item 28568968

 

  1. Developmentally Supportive Care in Congenital Heart Disease: A Concept Analysis.

Peterson JK, Evangelista LS.

J Pediatr Nurs. 2017 May 31. pii: S0882-5963(16)30173-7. doi: 10.1016/j.pedn.2017.05.007. [Epub ahead of print] Review.

PMID: 28579078

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Select item 28557188

 

  1. Descending aorta to right atrial fistula: Presenting with neonatal collapse.

Ho AB, Magee AG, Hayes N.

Catheter Cardiovasc Interv. 2017 May 30. doi: 10.1002/ccd.27129. [Epub ahead of print]

PMID: 28557188

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Select item 28562391

 

  1. Feasibility of high-pitch spiral dual-source CT angiography in children with complex congenital heart disease compared to retrospective-gated spiral acquisition.

Li T, Zhao S, Liu J, Yang L, Huang Z, Li J, Luo C, Li X.

Clin Radiol. 2017 May 30. pii: S0009-9260(17)30181-2. doi: 10.1016/j.crad.2017.05.005. [Epub ahead of print]

PMID: 28576437

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Select item 28557332

 

  1. [Infective endocarditis prophylaxis in congenital heart disease].

Di Filippo S.

Presse Med. 2017 May 30. pii: S0755-4982(17)30254-3. doi: 10.1016/j.lpm.2017.05.016. [Epub ahead of print] French.

PMID: 28576635

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Select item 28575225

 

  1. A Role for Primary Cilia in Aortic Valve Development and Disease.

Toomer KA, Fulmer D, Guo L, Drohan A, Peterson N, Swanson P, Brooks B, Mukherjee R, Body S, Lipschutz J, Wessels A, Norris RA.

Dev Dyn. 2017 May 27. doi: 10.1002/dvdy.24524. [Epub ahead of print]

PMID: 28556366

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Select item 28551818

 

  1. Pediatric heart disease simulation curriculum: Educating the pediatrician.

Harris TH, Adler M, Unti SM, McBride ME.

Congenit Heart Dis. 2017 May 26. doi: 10.1111/chd.12483. [Epub ahead of print]

PMID: 28547923

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Select item 28549113

 

  1. Identification of 22q11.2 Deletion Syndrome via Newborn Screening for Severe Combined Immunodeficiency.

Barry JC, Crowley TB, Jyonouchi S, Heimall J, Zackai EH, Sullivan KE, McDonald-McGinn DM.

J Clin Immunol. 2017 May 24. doi: 10.1007/s10875-017-0403-9. [Epub ahead of print]

PMID: 28540525

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Select item 28543795

 

  1. Pulmonary Hypertension in Infants, Children, and Young Adults.

Hansmann G.

J Am Coll Cardiol. 2017 May 23;69(20):2551-2569. doi: 10.1016/j.jacc.2017.03.575. Review.

PMID: 28521893

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Select item 28536747

 

  1. A Genetic Variant in FIGN Gene Reduces the Risk of Congenital Heart Disease in Han Chinese Populations.

Wang D, Chu M, Wang F, Zhou A, Ruan M, Chen Y.

Pediatr Cardiol. 2017 May 22. doi: 10.1007/s00246-017-1636-3. [Epub ahead of print]

PMID: 28534241

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Select item 28534240

 

  1. An Early Glenn Operation May be Associated with the Later Occurrence of Protein-Losing Enteropathy in Fontan Patients : Association of Early Glenn and Failing Fontan.

Unseld B, Stiller B, Borth-Bruhns T, du Bois F, Kroll J, Grohmann J, Fleck T.

Pediatr Cardiol. 2017 May 22. doi: 10.1007/s00246-017-1632-7. [Epub ahead of print]

PMID: 28534240

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Select item 28534239

 

  1. Transatlantic medical consultation and second opinion in pediatric cardiology has benefit past patient care: A case study in videoconferencing.

Kovacikova L, Zahorec M, Skrak P, Hanna BD, Lee Vogel R.

Congenit Heart Dis. 2017 May 19. doi: 10.1111/chd.12480. [Epub ahead of print]

PMID: 28523862

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Select item 28523857

 

  1. Long-term respiratory outcomes after primary total correction for tetralogy of Fallot and absent pulmonary valve in patient with respiratory symptoms.

Hoashi T, Iwasa T, Kagisaki K, Shimada M, Kurosaki K, Shiraishi I, Ichikawa H.

Congenit Heart Dis. 2017 May 19. doi: 10.1111/chd.12477. [Epub ahead of print]

PMID: 28523732

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Select item 28542743

 

  1. Neuroimaging, cardiovascular physiology, and functional outcomes in infants with congenital heart disease.

Claessens NHP, Kelly CJ, Counsell SJ, Benders MJNL.

Dev Med Child Neurol. 2017 May 19. doi: 10.1111/dmcn.13461. [Epub ahead of print] Review.

PMID: 28542743

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Select item 28544539

 

  1. Psychiatric Disorders and Function in Adolescents with Tetralogy of Fallot.

Holland JE, Cassidy AR, Stopp C, White MT, Bellinger DC, Rivkin MJ, Newburger JW, DeMaso DR.

J Pediatr. 2017 May 19. pii: S0022-3476(17)30595-4. doi: 10.1016/j.jpeds.2017.04.048. [Epub ahead of print]

PMID: 28533034

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Select item 28516823

 

  1. Predictors of health-related quality of life in children with chronic heart disease.

Niemitz M, Gunst DCM, Hövels-Gürich HH, Hofbeck M, Kaulitz R, Galm C, Berger F, Nagdyman N, Stiller B, Borth-Bruhns T, Konzag I, Balmer C, Goldbeck L.

Cardiol Young. 2017 May 18:1-10. doi: 10.1017/S1047951117000440. [Epub ahead of print]

PMID: 28516823

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Select item 28517030

 

  1. Birth weight, length and head circumference: Progression and impact over the outcome of patients with congenital heart disease.

Silveira DB, da Rosa EB, Correia JD, Trevisan P, Fiegenbaum M, Oliveira CA, Grapiglia CG, Nunes MR, Rosa RCM, Zen TD, Zen PRG, Rosa RFM.

Int J Cardiol. 2017 May 18. pii: S0167-5273(17)30305-4. doi: 10.1016/j.ijcard.2017.05.078. [Epub ahead of print]

PMID: 28539208

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Select item 28523472

 

  1. Assessment of coronary artery by prospective ECG-triggered 256 multi-slice CT on children with congenital heart disease.

Yao LP, Zhang L, Li HM, Ding M, Yu LW, Yang X, Li XM, Sun K.

Int J Cardiovasc Imaging. 2017 May 18. doi: 10.1007/s10554-017-1150-y. [Epub ahead of print]

PMID: 28523472

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Select item 28515370

 

  1. HDliveFlow with spatiotemporal image correlation for the diagnosis of congenital heart disease.

Ito M, AboEllail MAM, Yamamoto K, Kanenishi K, Tanaka H, Masaoka H, Hata T.

Ultrasound Obstet Gynecol. 2017 May 16. doi: 10.1002/uog.17519. [Epub ahead of print]

PMID: 28508399

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Select item 28343597

 

  1. Comparison of Echocardiography and 64-Multislice Spiral Computed Tomography for the Diagnosis of Pediatric Congenital Heart Disease.

Li A, Peng Z, Zhang C.

Med Sci Monit. 2017 May 13;23:2258-2266.

PMID: 28500278 Free PMC Article

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Select item 28502187

 

  1. Impaired ventilatory efficiency after closure of atrial or ventricular septal defect.

Heiberg J, Nyboe C, Hjortdal VE.

Scand Cardiovasc J. 2017 May 13:1-7. doi: 10.1080/14017431.2017.1326623. [Epub ahead of print]

PMID: 28502187

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Select item 28514318

 

  1. Cerebral Oxygen Saturation in Children With Congenital Heart Disease and Chronic Hypoxemia.

Kussman BD, Laussen PC, Benni PB, McGowan FX Jr, McElhinney DB.

Anesth Analg. 2017 May 12. doi: 10.1213/ANE.0000000000002073. [Epub ahead of print]

PMID: 28514318

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Select item 28506578

 

  1. Evaluation of athletes with complex congenital heart disease.

Bates BA, Richards C, Hall M, Kerut EK, Campbell W, McMullan MR.

Echocardiography. 2017 May 12. doi: 10.1111/echo.13562. [Epub ahead of print]

PMID: 28497583

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Select item 28500462

 

  1. Perfusion index and left ventricular output correlation in healthy term infants.

Corsini I, Cecchi A, Coviello C, Dani C.

Eur J Pediatr. 2017 May 12. doi: 10.1007/s00431-017-2920-1. [Epub ahead of print] Erratum in: Eur J Pediatr. 2017 Jun 5;:.

PMID: 28500462

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Select item 28506649

 

  1. Exercise Training In Athletes With Heart Disease.

Fernandez AB, Thompson PD.

Prog Cardiovasc Dis. 2017 May 12. pii: S0033-0620(17)30065-8. doi: 10.1016/j.pcad.2017.05.004. [Epub ahead of print] Review.

PMID: 28502848

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Select item 28583678

 

  1. The effect of an electronic health record-based tool on abnormal pediatric blood pressure recognition.

Twichell SA, Rea CJ, Melvin P, Capraro AJ, Mandel JC, Ferguson MA, Nigrin DJ, Mandl KD, Graham D, Zachariah JP.

Congenit Heart Dis. 2017 May 11. doi: 10.1111/chd.12469. [Epub ahead of print]

PMID: 28493451

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Select item 28493446

 

  1. Family perception of unmet support needs following a diagnosis of congenital coronary anomaly in children: Results of a survey.

Agrawal H, Wright OK, Carberry KE, Sexson Tejtel SK, Mery CM, Molossi S.

Congenit Heart Dis. 2017 May 11. doi: 10.1111/chd.12473. [Epub ahead of print]

PMID: 28493446

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Select item 28498910

 

  1. Physical activity evaluation in children with congenital heart disease.

Voss C, Harris KC.

Heart. 2017 May 10. pii: heartjnl-2017-311340. doi: 10.1136/heartjnl-2017-311340. [Epub ahead of print] Review.

PMID: 28490620

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Select item 28501374

 

  1. The Effect of the Superior Cavopulmonary Anastomosis on Ventricular Remodeling in Infants with Single Ventricle.

Margossian R, Zak V, Shillingford AJ, Hlavacek AM, Cnota JF, Puchalski MD, Levine JC, McCrindle BW, Cohen MS, Altmann K, Barker PC, Hsu DT, Colan SD; Pediatric Heart Network Investigators.

J Am Soc Echocardiogr. 2017 May 10. pii: S0894-7317(17)30183-9. doi: 10.1016/j.echo.2017.03.005. [Epub ahead of print]

PMID: 28501374

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Select item 28490416

 

  1. Left ventricular noncompaction cardiomyopathy in a patient with trisomy 13: A report and review of the literature.

Hayashi A, Kumada T, Nozaki F, Hiejima I, Shibata M, Kusunoki T, Fujii T.

Am J Med Genet A. 2017 May 9. doi: 10.1002/ajmg.a.38270. [Epub ahead of print]

PMID: 28488311

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Select item 28536530

 

  1. Prevalence of Congenital Heart Disease among Infants from 2012 to 2014 in Langfang, China.

Sun PF, Ding GC, Zhang MY, He SN, Gao Y, Wang JH.

Chin Med J (Engl). 2017 May 5;130(9):1069-1073. doi: 10.4103/0366-6999.204923.

PMID: 28469102 Free PMC Article

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Select item 28280240

 

  1. Erratum to: Critical Congenital Heart Disease Newborn Screening Implementation: Lessons Learned.

McClain MR, Hokanson JS, Grazel R, Van Naarden Braun K, Garg LF, Morris MR, Moline K, Urquhart K, Nance A, Randall H, Sontag MK.

Matern Child Health J. 2017 May 5. doi: 10.1007/s10995-017-2295-y. [Epub ahead of print] No abstract available.

PMID: 28477067

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Select item 28472932

 

  1. miR-21 is associated with fibrosis and right ventricular failure.

Reddy S, Hu DQ, Zhao M, Blay E Jr, Sandeep N, Ong SG, Jung G, Kooiker KB, Coronado M, Fajardo G, Bernstein D.

JCI Insight. 2017 May 4;2(9). pii: 91625. doi: 10.1172/jci.insight.91625. [Epub ahead of print]

PMID: 28469078 Free PMC Article

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Select item 28473357

 

  1. A HAND to TBX5 Explains the Link Between Thalidomide and Cardiac Diseases.

Khalil A, Tanos R, El-Hachem N, Kurban M, Bouvagnet P, Bitar F, Nemer G.

Sci Rep. 2017 May 3;7(1):1416. doi: 10.1038/s41598-017-01641-3.

PMID: 28469241 Free PMC Article

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Select item 28302752

 

  1. Lower Circulating Folate Induced by a Fidgetin Intronic Variant Is Associated With Reduced Congenital Heart Disease Susceptibility.

Wang D, Wang F, Shi KH, Tao H, Li Y, Zhao R, Lu H, Duan W, Qiao B, Zhao SM, Wang H, Zhao JY.

Circulation. 2017 May 2;135(18):1733-1748. doi: 10.1161/CIRCULATIONAHA.116.025164. Epub 2017 Mar 16.

PMID: 28302752

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Select item 28464509

 

  1. Neuro-developmental outcome in single-ventricle patients: is the Norwood procedure a risk factor?

Rotermann I, Logoteta J, Falta J, Wegner P, Jung O, Dütschke P, Scheewe J, Kramer HH, Hansen JH.

Eur J Cardiothorac Surg. 2017 May 2. doi: 10.1093/ejcts/ezx119. [Epub ahead of print]

PMID: 28472306

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Select item 28472474

 

  1. Toward evidence-based diagnosis of myocarditis in children and adolescents: Rationale, design, and first baseline data of MYKKE, a multicenter registry and study platform.

Messroghli DR, Pickardt T, Fischer M, Opgen-Rhein B, Papakostas K, Böcker D, Jakob A, Khalil M, Mueller GC, Schmidt F, Kaestner M, Udink Ten Cate FEA, Wagner R, Ruf B, Kiski D, Wiegand G, Degener F, Bauer UMM, Friede T, Schubert S; MYKKE Consortium.

Am Heart J. 2017 May;187:133-144. doi: 10.1016/j.ahj.2017.02.027. Epub 2017 Feb 24.

PMID: 28454797

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Select item 28283176

 

  1. Growth characteristics and endocrine abnormalities in 22q11.2 deletion syndrome.

Levy-Shraga Y, Gothelf D, Goichberg Z, Katz U, Somech R, Pinhas-Hamiel O, Modan-Moses D.

Am J Med Genet A. 2017 May;173(5):1301-1308. doi: 10.1002/ajmg.a.38175. Epub 2017 Feb 16.

PMID: 28421700

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Select item 28371479

 

  1. Oral-facial-digital syndrome type 1 in males: Congenital heart defects are included in its phenotypic spectrum.

Bouman A, Alders M, Oostra RJ, van Leeuwen E, Thuijs N, van der Kevie-Kersemaekers AM, van Maarle M.

Am J Med Genet A. 2017 May;173(5):1383-1389. doi: 10.1002/ajmg.a.38179. Epub 2017 Apr 3.

PMID: 28371265 Free PMC Article

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Select item 28500812

 

  1. Birth prevalence of congenital heart disease: A cross-sectional observational study from North India.

Al-Mendalawi MD.

Ann Pediatr Cardiol. 2017 May-Aug;10(2):220. doi: 10.4103/apc.APC_124_16. No abstract available.

PMID: 28566838 Free PMC Article

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Select item 28566834

 

  1. Functional tricuspid stenosis: a rare presentation of suspected rhabdomyoma as congenital cyanotic heart disease.

Nair A, Rajesh GN, Sajeev CG.

Cardiol Young. 2017 May;27(4):808-811. doi: 10.1017/S1047951116002110. Epub 2017 Jan 12.

PMID: 28077182

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Select item 27373527

 

  1. Pulmonary Perfusion Changes Following Extracardiac Lateral Fontan and Bilateral Bidirectional Glenn Shunt in Hypoplastic Right Ventricle With Duplicated Superior Vena Cava.

Salas Fragomeni RA, Turkbey EB, Jones BC, Solnes LB, Rowe SP.

Clin Nucl Med. 2017 May;42(5):377-378. doi: 10.1097/RLU.0000000000001605.

PMID: 28240666

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Select item 28580610

 

  1. Speaking to children and their families about congenital heart disease: Ushering in a new era of healthcare literacy.

Penny DJ.

Congenit Heart Dis. 2017 May;12(3):241. doi: 10.1111/chd.12474. No abstract available.

PMID: 28580609

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Select item 28580608

 

  1. Dysphagia in infants with single ventricle anatomy following stage 1 palliation: Physiologic correlates and response to treatment.

McGrattan KE, McGhee H, DeToma A, Hill EG, Zyblewski SC, Lefton-Greif M, Halstead L, Bradley SM, Martin-Harris B.

Congenit Heart Dis. 2017 May;12(3):382-388. doi: 10.1111/chd.12456. Epub 2017 Feb 28.

PMID: 28244680

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Select item 28225219

 

  1. Educational intervention for improving the appropriateness of transthoracic echocardiograms ordered by pediatric cardiologists.

Sachdeva R, Douglas PS, Kelleman MS, McCracken CE, Lopez L, Stern KWD, Eidem BW, Benavidez OJ, Weiner RB, Welch E, Campbell RM, Lai WW.

Congenit Heart Dis. 2017 May;12(3):373-381. doi: 10.1111/chd.12455. Epub 2017 Feb 22.

PMID: 28225219

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Select item 28225202

 

  1. Cardiac remodeling in preterm infants with prolonged exposure to a patent ductus arteriosus.

de Waal K, Phad N, Collins N, Boyle A.

Congenit Heart Dis. 2017 May;12(3):364-372. doi: 10.1111/chd.12454. Epub 2017 Feb 22.

PMID: 28225202

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Select item 28217850

 

  1. Practice variability in management of infectious issues in heterotaxy: A survey of pediatric cardiologists.

Loomba RS, Geddes G, Shillingford AJ, Hehir DA.

Congenit Heart Dis. 2017 May;12(3):332-339. doi: 10.1111/chd.12448. Epub 2017 Feb 15.

PMID: 28199048

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Select item 28140523

 

  1. Tissue plasminogen activator for neonatal coronary thrombosis presenting with mitral valve regurgitation and impaired ventricular function.

Molkara D, Silva Sepulveda JA, Do T, Davis C, Goldstein GP, Moore JW, El-Said HG.

Congenit Heart Dis. 2017 May;12(3):270-274. doi: 10.1111/chd.12432. Epub 2017 Jan 31.

PMID: 28140523

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Select item 28121380

 

  1. Practice trends over time in the care of infants with hypoplastic left heart syndrome: A report from the National Pediatric Cardiology Quality Improvement Collaborative.

Carlo WF, Cnota JF, Dabal RJ, Anderson JB.

Congenit Heart Dis. 2017 May;12(3):315-321. doi: 10.1111/chd.12442. Epub 2017 Jan 25.

PMID: 28121380

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Select item 28092429

 

  1. Incidence, morphology, and progression of bicuspid aortic valve in pediatric and young adult subjects with coexisting congenital heart defects.

Niaz T, Poterucha JT, Johnson JN, Craviari C, Nienaber T, Palfreeman J, Cetta F, Hagler DJ.

Congenit Heart Dis. 2017 May;12(3):261-269. doi: 10.1111/chd.12429. Epub 2016 Nov 28.

PMID: 27893194

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Select item 27893189

 

  1. Defining pediatric inpatient cardiology care delivery models: A survey of pediatric cardiology programs in the USA and Canada.

Mott AR, Neish SR, Challman M, Feltes TF.

Congenit Heart Dis. 2017 May;12(3):294-300. doi: 10.1111/chd.12438. Epub 2016 Nov 25.

PMID: 27885832

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Select item 27874259

 

  1. Pediatric cardiac readmissions: An opportunity for quality improvement?

Sacks JH, Kelleman M, McCracken C, Glanville M, Oster M.

Congenit Heart Dis. 2017 May;12(3):282-288. doi: 10.1111/chd.12436. Epub 2016 Nov 22.

PMID: 27874252

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Select item 27865060

 

  1. Reducing variation in feeding newborns with congenital heart disease.

Simsic JM, Carpenito KR, Kirchner K, Peters S, Miller-Tate H, Joy B, Galantowicz M.

Congenit Heart Dis. 2017 May;12(3):275-281. doi: 10.1111/chd.12435. Epub 2016 Nov 16.

PMID: 27865060

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Select item 28374180

 

  1. Coronary Artery Anomalies: When You Need to Worry.

Kochar A, Kiefer T.

Curr Cardiol Rep. 2017 May;19(5):39. doi: 10.1007/s11886-017-0854-x. Review.

PMID: 28374180

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Select item 28345243

 

  1. Myocardial fibrosis in congenital and pediatric heart disease.

Tian J, An X, Niu L.

Exp Ther Med. 2017 May;13(5):1660-1664. doi: 10.3892/etm.2017.4224. Epub 2017 Mar 10.

PMID: 28565750 Free PMC Article

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Select item 28507990

 

  1. Development of an Online, Evidence-Based Patient Information Portal for Congenital Heart Disease: A Pilot Study.

Etnel JRG, van Dijk APJ, Kluin J, Bertels RA, Utens EMWJ, van Galen E; Regina The, Bogers AJJC, Takkenberg JJM.

Front Cardiovasc Med. 2017 May 1;4:25. doi: 10.3389/fcvm.2017.00025. eCollection 2017.

PMID: 28507990 Free PMC Article

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Select item 28346832

 

  1. Association of airway abnormalities with 22q11.2 deletion syndrome.

Sacca R, Zur KB, Crowley TB, Zackai EH, Valverde KD, McDonald-McGinn DM.

Int J Pediatr Otorhinolaryngol. 2017 May;96:11-14. doi: 10.1016/j.ijporl.2017.02.012. Epub 2017 Feb 21.

PMID: 28390597

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Select item 27784831

 

  1. N-Terminal Pro-B-Type Natriuretic Peptide and Phonocardiography in Differentiating Innocent Cardiac Murmurs from Congenital Cardiac Anomalies in Asymptomatic Puppies.

Marinus SM, van Engelen H, Szatmári V.

J Vet Intern Med. 2017 May;31(3):661-667. doi: 10.1111/jvim.14667. Epub 2017 Mar 18.

PMID: 28316101 Free PMC Article

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Select item 26616137

 

  1. A Rare Cause of Shock in an Infant: Cor Triatriatum.

Vayngortin T, Rosenfeld H, Mansour K.

Pediatr Emerg Care. 2017 May 1. doi: 10.1097/PEC.0000000000001162. [Epub ahead of print]

PMID: 28463946

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Select item 28403058

 

  1. Multiorgan Involvement Confounding the Diagnosis of Bartonella henselae Infective Endocarditis in Children With Congenital Heart Disease.

Ouellette CP, Joshi S, Texter K, Jaggi P.

Pediatr Infect Dis J. 2017 May;36(5):516-520. doi: 10.1097/INF.0000000000001510.

PMID: 28403058

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Select item 28403044

 

  1. Comparing First- and Second-year Palivizumab Prophylaxis in Patients With Hemodynamically Significant Congenital Heart Disease in the CARESS Database (2005-2015).

Li A, Wang DY, Lanctôt KL, Mitchell I, Paes BA; CARESS Investigators.

Pediatr Infect Dis J. 2017 May;36(5):445-450. doi: 10.1097/INF.0000000000001357.

PMID: 28403044

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Select item 28258649

 

  1. Cardiac manifestations of inherited metabolic disease in children.

Lloyd DF, Vara R, Mathur S.

Pediatr Int. 2017 May;59(5):525-529. doi: 10.1111/ped.13272. Review.

PMID: 28258649

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Select item 27289364

 

  1. Risk factors for pulmonary arterial hypertension in children and young adults.

Naumburg E, Söderström L, Huber D, Axelsson I.

Pediatr Pulmonol. 2017 May;52(5):636-641. doi: 10.1002/ppul.23633. Epub 2016 Nov 1.

PMID: 27801982

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Select item 28243677

 

  1. [Sports in children with congenital heart diseases].

Bosser G, Moulin-Zinsch A, Fischer-Atalla R.

Presse Med. 2017 May;46(5):509-522. doi: 10.1016/j.lpm.2017.03.005. Epub 2017 Apr 21. French.

PMID: 28434627

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Select item 28314442

 

  1. [Congenital heart disease: Recent technical advances in three-dimensional echocardiography].

Karsenty C, Hadeed K, Acar P.

Presse Med. 2017 May;46(5):482-489. doi: 10.1016/j.lpm.2016.11.016. Epub 2017 Jan 4. French.

PMID: 28063755

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Select item 28038838

 

  1. Double Aortic Arch With a Retroaortic Innominate Vein: A Rare Association Diagnosed Using Cardiac Magnetic Resonance Imaging.

Walsh R, Cracchiolo V.

World J Pediatr Congenit Heart Surg. 2017 May;8(3):394-395. doi: 10.1177/2150135117690097. No abstract available.

PMID: 28520543

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Select item 28520541

 

  1. Congenital pseudoaneurysm of the mitral-aortic intervalvular fibrosa: a case report.

Harrington JK, Glickstein J, Shah A.

Cardiol Young. 2017 May 29:1-4. doi: 10.1017/S1047951117000890. [Epub ahead of print]

PMID: 28552080

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Select item 28552079

 

  1. Association between vascular rings and learning performance: A cross-sectional study.

Chen FL, Liaw YP, Hsu SY, Nfor ON.

J Clin Ultrasound. 2017 May 29. doi: 10.1002/jcu.22502. [Epub ahead of print]

PMID: 28555926

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Select item 28553678

 

  1. Major Aortopulmonary Collateral Arteries With Anatomy Other Than Pulmonary Atresia/Ventricular Septal Defect.

Patrick WL, Mainwaring RD, Reinhartz O, Punn R, Tacy T, Hanley FL.

Ann Thorac Surg. 2017 May 17. pii: S0003-4975(17)30291-6. doi: 10.1016/j.athoracsur.2017.02.029. [Epub ahead of print]

PMID: 28527961

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Select item 28515113

 

  1. Mid-term Risk for Subclinical Atherosclerosis and Chronic Myocarditis in Children with Kawasaki Disease and Transient Coronary Abnormalities.

Parihar M, Singh S, Vignesh P, Gupta A, Rohit M.

Pediatr Cardiol. 2017 May 17. doi: 10.1007/s00246-017-1626-5. [Epub ahead of print]

PMID: 28512721

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Select item 28512720

 

  1. Comparison of two-dimensional and three-dimensional echocardiographic strain in children with CHD.

Wisotzkey BL, Soriano BD, Buddhe S.

Cardiol Young. 2017 May 15:1-9. doi: 10.1017/S1047951117000762. [Epub ahead of print]

PMID: 28502268

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Select item 28284501

 

  1. Sudden death in a pediatric heart transplant recipient with peripheral eosinophilia and eosinophilic myocardial infiltrates.

McEachern W, Godown J, Dodd DA, Dipchand AI, Conway JL, Wilson GJ, Hoffman RD.

Pediatr Transplant. 2017 May 14. doi: 10.1111/petr.12937. [Epub ahead of print]

PMID: 28504342

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Select item 28511801

 

  1. Mitral arcade: A rare case presenting with fatigue and cough.

Aydın Sahin D, Ceylan O.

Echocardiography. 2017 May 12. doi: 10.1111/echo.13554. [Epub ahead of print]

PMID: 28497556

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Select item 28583678

 

  1. Pediatric out-of-hospital cardiac arrest caused by left coronary-artery agenesis with primary shockable rhythm. A brief report.

Weigeldt M, Lahmann S, Krieger K, Buttenberg S, Stephan V, Stiller B, Stengel D.

Am J Emerg Med. 2017 May 11. pii: S0735-6757(17)30375-3. doi: 10.1016/j.ajem.2017.05.011. [Epub ahead of print]

PMID: 28549578

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Select item 28493591

 

  1. Bacterial infections after pediatric heart transplantation: Epidemiology, risk factors and outcomes.

Rostad CA, Wehrheim K, Kirklin JK, Naftel D, Pruitt E, Hoffman TM, L’Ecuyer T, Berkowitz K, Mahle WT, Scheel JN.

J Heart Lung Transplant. 2017 May 11. pii: S1053-2498(17)31790-4. doi: 10.1016/j.healun.2017.05.009. [Epub ahead of print]

PMID: 28583371

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Select item 28498231

 

  1. Reduced cortical volume and thickness and their relationship to medical and operative features in post-Fontan children and adolescents.

Watson CG, Stopp C, Wypij D, Newburger JW, Rivkin MJ.

Pediatr Res. 2017 May 3. doi: 10.1038/pr.2017.30. [Epub ahead of print]

PMID: 28157834

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Select item 28460651

 

  1. Recessive TAF1A mutations reveal ribosomopathy in siblings with end-stage pediatric dilated cardiomyopathy.

Long PA, Theis JL, Shih YH, Maleszewski JJ, Abell Aleff PC, Evans JM, Xu X, Olson TM.

Hum Mol Genet. 2017 May 2. doi: 10.1093/hmg/ddx169. [Epub ahead of print]

PMID: 28472305

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Select item 28562282

 

  1. Aspirin Dose and Prevention of Coronary Abnormalities in Kawasaki Disease.

Dallaire F, Fortier-Morissette Z, Blais S, Dhanrajani A, Basodan D, Renaud C, Mathew M, De Souza AM, Dionne A, Blanchard J, Saulnier H, Kaspy K, Rached-d’Astous S, Dahdah N, McCrindle BW, Human DG, Scuccimarri R.

Pediatrics. 2017 May 2. pii: e20170098. doi: 10.1542/peds.2017-0098. [Epub ahead of print]

PMID: 28562282

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Select item 28454797

 

  1. Relation of Right Atrial Volume, Systemic Venous Dimensions, and Flow Patterns to Right Atrial Pressure in Infants and Children.

Patel SG, Woolman P, Li L, Craft M, Danford DA, Kutty S.

Am J Cardiol. 2017 May 1;119(9):1473-1478. doi: 10.1016/j.amjcard.2017.01.013. Epub 2017 Feb 10.

PMID: 28256251

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Select item 28332295

 

  1. Advanced cardiovascular imaging in Williams syndrome: Abnormalities, usefulness, and strategy for use.

Hills JA, Zarate YA, Danylchuk NR, Lepard T, Chen JC, Collins RT 2nd.

Am J Med Genet A. 2017 May;173(5):1194-1199. doi: 10.1002/ajmg.a.38138. Epub 2017 Mar 22.

PMID: 28332295

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Select item 28213406

 

  1. Correlation of electrocardiogram parameters and hemodynamic outcomes in patients with isolated secundum atrial septal defects.

Refaei M, Islam S, Mackie AS, Atallah J.

Ann Pediatr Cardiol. 2017 May-Aug;10(2):152-157. doi: 10.4103/0974-2069.205139.

PMID: 28566823 Free PMC Article

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Select item 28566822

 

  1. .A case of biatrial drainage of the right superior vena cava.

Iwata Y, Kojima A, Nakayama Y, Omoya K, Kuwahara T, Takeuchi T.

Asian Cardiovasc Thorac Ann. 2017 May;25(4):292-295. doi: 10.1177/0218492316641535. Epub 2016 Mar 27.

PMID: 27022086

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Select item 28317142

 

  1. Variability of antithrombotics use in patients with hypoplastic left heart syndrome and its variants following first- and second-stage palliation surgery: a national report using the National Pediatric Cardiology Quality Improvement Collaborative registry.

Ramachandran P, King E, Nebbia A, Beekman RH, Anderson JB.

Cardiol Young. 2017 May;27(4):731-738. doi: 10.1017/S1047951116001189. Epub 2016 Aug 30.

PMID: 27981915

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Select item 27869054

 

  1. A rare cause of cardiomyopathy in an infant: middle aortic syndrome.

Mir A, Stam B, Sperrazza C.

Cardiol Young. 2017 May;27(4):794-796. doi: 10.1017/S1047951116002018. Epub 2016 Nov 14.

PMID: 27839529

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Select item 27751193

 

  1. Factors influencing bacteraemia in patients with isomerism and CHD: the effects of functional splenic status and antibiotic prophylaxis.

Loomba RS, Pelech AN, Anderson RH.

Cardiol Young. 2017 May;27(4):639-647. doi: 10.1017/S1047951116000962. Epub 2016 Sep 29.

PMID: 27679871

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Select item 27645708

 

  1. Cholelithiasis in children with CHD: is it a problem?

Kargl S, Gitter R, Pumberger W.

Cardiol Young. 2017 May;27(4):630-633. doi: 10.1017/S1047951116000846. Epub 2016 Jun 20.

PMID: 27322515

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Select item 28258658

 

  1. De Novo Migraine With Aura After Surgical Repair of Aortic Coarctation.

Kato Y, Hayashi T, Kobayashi T, Masuoka A, Abe T, Hasebe T, Tanahashi N, Takao M.

Headache. 2017 May;57(5):792-795. doi: 10.1111/head.12995. Epub 2016 Dec 2.

PMID: 27910096

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Select item 28213054

 

  1. Influence of apical position on the left ventricular outflow tract obstruction in congenitally corrected transposition.

Lee ML, Chiu IS.

J Cardiol. 2017 May;69(5):785-789. doi: 10.1016/j.jjcc.2016.07.019. Epub 2016 Nov 11.

PMID: 27842759

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Select item 27554048