Pediatric Cardiology Featured Articles of November 2016

The United States Pediatric Cardiology 2015 Workforce Assessment: A Survey of Current Training and Employment Patterns: A Report of the American College of Cardiology, American Heart Association, American Academy of Pediatrics Section on Cardiology and Cardiac Surgery, and Society for Pediatric Cardiology Training Program Directors.

Writing Committee Members. Ross RD, Srivastava S, Cabrera AG, Ruch-Ross HS, Radabaugh CL, Minich LL, Mahle WT, Brown DW.

J Am Coll Cardiol. 2016 Nov 21. pii: S0735-1097(16)36323-9. doi: 10.1016/j.jacc.2016.09.921. [Epub ahead of print] No abstract available.

Take Home Points:

  1. The number of pediatric cardiology fellowship openings is projected to outnumber the available jobs over the next 2 years.
  2. The current job market for finishing pediatric cardiology fellows is perceived as “somewhat difficult”.
  3. The most difficult fields within pediatric cardiology to find a job are cardiac catheterization, electrophysiology and general cardiology. The least challenging fields to find jobs are critical care cardiology, heart failure/transplant and adult congenital cardiology.

Abarbanell picture smallCommentary from Dr. Ginnie Abarbanell (Atlanta), section editor of Pediatric Cardiology Journal Watch: How competitive is the current job market for pediatric cardiologists in the US?  Are we training too many pediatric cardiology fellows?

The American College of Cardiology (ACC), American Heart Association (AHA), American Academy of Pediatrics (AAP) and the Society for Pediatric Cardiology Training Program Directors conducted a survey to try to answer these questions.  The survey response rate was 28% with 823 completed surveys.  The response rate was higher among pediatric cardiology fellowship directors (87%) and division chiefs (71%).  Of the program directors that responded to the survey it was reported that no current or previous third or fourth year pediatric cardiology graduates chose or were forced to take a job outside of pediatric cardiology. Over 50% of fellows after completing a 3-year core fellowship and 89% of those who completed a fourth year of subspecialty training entered into academic practice. Program directors were asked to rank the ease of which the pediatric cardiology fellows were obtaining jobs and ranked the job market as “somewhat difficult” (Figure 1). This survey found that the most difficult fields to find jobs were cardiac catheterization, electrophysiology and general cardiology while the least challenging fields to find jobs were critical care cardiology, heart failure/transplant and adult congenital cardiology (Figure 2).  Division chiefs reported that there have been 142 new hires/year with 53% of the positions being filled by fellows with 4 or more years of training, followed by 26% being filled by faculty from another institution and only 21% from 3-year core fellowship graduates.  Using the division chief’s survey responses there is projected to be 135 job openings/year over the next two years.  In comparison there are currently 141 fellowship match openings in pediatric cardiology per year and the number of match opening has nearly doubled over the last decade (Figure 3).  In response to the questions posed above: “How competitive is the current job market for pediatric cardiologists in the US and are we training too many pediatric cardiology fellows?”  The authors conclude “there is concern that those graduating in the next few years may have more trouble finding jobs in their area of interest.”

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Prevalence and pattern of executive dysfunction in school age children with congenital heart disease.

Sanz JH, Berl MM, Armour AC, Wang J, Cheng YI, Donofrio MT.

Congenit Heart Dis. 2016 Nov 11. doi: 10.1111/chd.12427. [Epub ahead of print]

Take Home Points:

  1. Parents of children with congenital heart disease report higher executive dysfunction, in particular for working memory and flexibility.
  2. Male gender, prematurity (< 37 weeks) and CHD with aortic obstruction were predictive of greater impairments in executive function in this study.
  3. A clinically elevated score on the BRIEF (Behavior Rating Inventory of Executive Function) did not increase the odds of receiving special education services.
  4. Findings from this study suggest that children with CHD who may qualify are not receiving special education services.

Commentary from Dr. Ginnie Abarbanell (Atlanta), section editor of Pediatric Cardiology Journal Watch: Many recent studies have documented that children with congenital heart disease (CHD) have neurodevelopmental deficits.  This study focuses on executive function (executive function is the ability for a person to complete purposeful and goal directed activity) in children with CHD who underwent cardiac surgery within the first year of life.  91 children (mean age 9 years) were recruited via social media, in-hospital advertisements and at cardiology or neuropsychology clinic visits.  These selection methods may well have biased the results. Their parents completed the Behavior Rating Inventory of Executive Function (BRIEF) and a medical history questionnaire.  The results of the BRIEF were compared to a control sample from a normative database.  Parents reported higher executive dysfunction, in particular for working memory and flexibility compared to the control sample.  Male gender, prematurity (< 37 weeks) and CHD with aortic obstruction were predictive of greater impairments in executive function.  The type of surgical repair (single ventricle vs. biventricular repair) did not predict a higher degree of executive dysfunction.

A third of children with CHD received support at school with either an IEP, 504 or similar student support plan if in private school.  However, a clinically elevated score on the BRIEF did not increase the odds of receiving special school support (See Table 4).  There was a trend for children who were more impulsive (i.e. had inhibitory control problems) to received special school services.  As the authors highlight in the discussion “this makes intuitive sense, since impulsive children can be disruptive in a classroom setting.” But only 22% of the children in this study were noted to have issues with inhibitory control. Additionally, “This study also suggests that many children who may qualify for services and supports in the school setting are not receiving them.”  This study supports that neurodevelopmental assessment in children who have undergone cardiac surgical repair is needed especially to identify children who would benefit from special school services and support.

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White Matter Volume Predicts Language Development in Congenital Heart Disease.

Rollins CK, Asaro LA, Akhondi-Asl A, Kussman BD, Rivkin MJ, Bellinger DC, Warfield SK, Wypij D, Newburger JW, Soul JS.

J Pediatr. 2016 Nov 9. pii: S0022-3476(16)31054-X. doi: 10.1016/j.jpeds.2016.09.070. [Epub ahead of print]

Take Home Points:

  1. Children following biventricular repair of congenital heart disease (CHD) have neurodevelopmental delays at 1 year of age.
  2. Brain MRI at 1 year of age in infants with CHD demonstrated decreased total brain volume, cerebral white matter and brainstem volumes in comparison to healthy controls.
  3. These significant reductions in brain volumes, especially reduction in cerebral white matter correlated to deficits in language development in particular the development of phrases and gestures as well as vocabulary comprehension.

Commentary from Dr. Ginnie Abarbanell (Atlanta), section editor of Pediatric Cardiology Journal Watch:  This study from Boston, MA correlated brain MRI findings at 1 year of age in patients with congenital heart disease (CHD) with neurodevelopmental testing.  48 infants with biventricular CHD (transposition of the great arteries, tetralogy of Fallot, Truncus arteriosus, ventricular septal defect or atrioventricular septal defect) who underwent cardiac surgery prior to 9 months of age were included in this study.  Infants underwent a brain MRI and neurodevelopmental testing consisting of Bayley Scales of Infant Development-II V(BSID-II) and the MacArthur-Bates Communicative Development Inventories (CDI) at 1 year of life.  BSID-II is a used to evaluate global neurodevelopment while CDI specifically evaluates language development.  On brain MRI, infants with CHD had significant reductions in total brain, cerebral white matter and brainstem volumes compared to a control group of 13 healthy infants of comparable ages.  Additionally, neurologic evaluation at 1 year was abnormal in over 50% of infants with CHD.  Infants with CHD scored significantly lower on the BSID-II (both psychomotor and mental developmental indices) compared to the control group and significantly below age and sex norms on the CDI.  The MRI findings of reduced brain volumes did not correlate to the findings on the BSID-II but did correlated to lower results on the CDI.  Specifically, cerebral white matter and brainstem volume reductions significantly correlated to development of phrases and gestures as well as vocabulary comprehension.  See Table V and Figure.  The authors concluded:  “Following reparative cardiac surgery, head growth normalized yet cerebral white matter and brainstem volumes remained small. Our findings suggest that persistent reduction in brain volumes in biventricular CHD months after surgery may be driven by early injury to and/or altered development of white matter, and that these observed structural differences are associated with language development.”

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Adiposity and Cardiovascular Risk Factor Variables in Childhood are Associated With Premature Death From Coronary Heart Disease in Adults: The Bogalusa Heart Study.

Berenson GS, Srinivasan SR, Xu JH, Chen W.

Am J Med Sci. 2016 Nov;352(5):448-454. doi: 10.1016/j.amjms.2016.08.006.

Take Home Points:

  1. The Bogalusa study has spanned a period of 40 years and this recent publication examines risk factors that present in childhood that could be associated with coronary artery disease (CAD) or myocardial infarction (MI) related deaths as an adult.
  2. This study found that non HDL cholesterol, body mass index (BMI) and blood pressure increased over time from childhood to adulthood in subjects that had died from CAD and/or MI compared to the living cohort.
  3. Additionally, logistic regression found a higher risk for CAD or MI deaths for subjects of male sex that had increased BMI and mean arterial blood pressure over time.

Commentary from Dr. Ginnie Abarbanell (Atlanta), section editor of Pediatric Cardiology Journal Watch:  The Bogalusa study began over 40 years ago in 1973 to identify risk factors for heart disease.  Several cross-sectional surveys have been performed on 5991 subjects from 1973-2010.  Deaths within this cohort have been tracked and over 600 deaths have been documented over the study duration.  This publication specifically evaluated the deaths secondary to cardiovascular causes.  There were 97 cardiovascular deaths of which 46 deaths were considered secondary to coronary artery disease (CAD) or myocardial infarction (MI).   The mean age of death within those 46 deaths was 44.7 years.  Non HDL cholesterol, body mass index (BMI) and blood pressure increased over time in those subjects that had died from CAD and/or MI compared to the living cohort.  See Figure.  Logistic regression found a higher risk for CAD or MI deaths for subjects of male sex, larger BMI and higher mean arterial blood pressure.  This study would suggest that increased BMI as well as increased blood pressure in childhood and adolescence are contributors to increased risk of early CAD/MI deaths.  The study does not address whether therapy could later these outcomes.

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The importance of social media for patients and families affected by congenital anomalies: A Facebook cross-sectional analysis and user survey.

Jacobs R, Boyd L, Brennan K, Sinha CK, Giuliani S.

J Pediatr Surg. 2016 Nov;51(11):1766-1771. doi: 10.1016/j.jpedsurg.2016.07.008.

Take Home Points:

  1. Our patients are turning to social media and the Internet for medical information.
  2. This survey of Facebook users who identified themselves or a member of their family as affected by either anorectal malformation, congenital diaphragmatic hernia, congenital disease (CHD) and hypospadias/epispadias found that 84% would like to have healthcare professionals take an active role in social media. (63% of respondents identified themselves or a member of their family as affected by CHD)
  3. A third of the survey responders felt they did not receive adequate support from their healthcare system/providers.
  4. These results demonstrate that our patients and their families feel that the healthcare system and providers need to develop an appropriate avenue for communicating with our patients via social media.

Commentary from Dr. Ginnie Abarbanell (Atlanta), section editor of Pediatric Cardiology Journal Watch:  We are all aware in this era our patients are turning to the Internet and social media for information and advice.  This study from the United Kingdom sought to evaluate the demographics and needs of individuals using Facebook for information and support related to four congenital anomalies associated with long term morbidity:  anorectal malformation, congenital diaphragmatic hernia, congenital disease (CHD) and hypospadias/epispadias.  Researchers used a keyword search in Facebook to identify relevant Groups/Pages and posted an anonymous survey on Facebook related to the group/page demographics and healthcare needs.  54 groups and 24 pages in Facebook were found.  Specifically, there were 9 groups and 7 pages identified which related to CHD.  Among the 4 groups noted above there were 16,191 group members and 48,766 page likes.  1133 individuals responded to the survey within 2 months of initially posting the survey on Facebook.  Of the respondents 63% identified themselves or a member of their family as affected by CHD. The survey responders were predominantly women (mothers of affected individuals) 26-40 years of age.  The common reasons for joining the Facebook groups/pages were: seeking support, education, making friends, and providing support to others.    84% of respondents would like to have healthcare professionals take an active role in the Facebooks groups and 97% stated they would join a group linked to their primary hospital.  A third (31%) felt they did not receive adequate support from their healthcare system/providers.  The results of this study would support a more active role for healthcare providers in social media.  However, as the authors discuss there is concern regarding the legality of providing advice online as well as issues with patient confidentiality and professional boundaries. Hence, any online forum would need to be “tightly regulated” to ensure appropriate content and confidentiality.  The final sentence of this study is a quote from a survey respondent, which sums up the status of healthcare involvement in social media. “Healthcare must move to the next level and providers must begin to actively engage on a broader scope.”

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Pediatric Cardiology Articles – November 2016

  1. Defining pediatric inpatient cardiology care delivery models: A survey of pediatric cardiology programs in the USA and Canada.

Mott AR, Neish SR, Challman M, Feltes TF.

Congenit Heart Dis. 2016 Nov 25. doi: 10.1111/chd.12438. [Epub ahead of print]

  1. Trends, microbiology, and outcomes of infective endocarditis in children during 2000-2010 in the United States.

Gupta S, Sakhuja A, McGrath E, Asmar B.

Congenit Heart Dis. 2016 Nov 25. doi: 10.1111/chd.12425. [Epub ahead of print]

  1. Limited Ventricular Preload is the Main Reason for Reduced Stress Reserve After Atrial Baffle Repair.

Eicken A, Michel J, Hager A, Tanase D, Kaemmerer H, Cleuziou J, Hess J, Ewert P.

Pediatr Cardiol. 2016 Nov 24. [Epub ahead of print]

  1. Relationship Between Habitual Exercise and Performance on Cardiopulmonary Exercise Testing Differs Between Children With Single and Biventricular Circulations.

O’Byrne ML, Desai S, Lane M, McBride M, Paridon S, Goldmuntz E.

Pediatr Cardiol. 2016 Nov 23. [Epub ahead of print]

  1. Cardiopulmonary Exercise Testing in Fontan Patients With and Without Isomerism (Heterotaxy) as Compared to Patients With Primary Ciliary Dyskinesia and Subjects With Structurally Normal Hearts.

Loomba RS, Danduran M, Nielsen KG, Ring AM, Kovach J, Anderson RH.

Pediatr Cardiol. 2016 Nov 23. [Epub ahead of print]

  1. Global Deformation Parameters Response to Exercise in Adolescents with Repaired Tetralogy of Fallot.

Mese T, Guven B, Yilmazer MM, Demirol M, Çoban Ş, Karadeniz C.

Pediatr Cardiol. 2016 Nov 23. [Epub ahead of print]

  1. Accelerated Cardiac Rhabdomyoma Regression with Everolimus in Infants with Tuberous Sclerosis Complex.

Aw F, Goyer I, Raboisson MJ, Boutin C, Major P, Dahdah N.

Pediatr Cardiol. 2016 Nov 23. [Epub ahead of print]

  1. Elevated serum levels of ghrelin and TNF-α in patients with cyanotic and acyanotic congenital heart disease.

Zhang S, Guo GL, Yang LL, Sun LQ.

World J Pediatr. 2016 Nov 23. [Epub ahead of print]

  1. Jellyfish-Like Accessory Mitral Valve Tissue Causing Near-Collapse in a Young Child.

Kato H, Escudero C, Sherwin E, Hosking M, Gandhi SK.

World J Pediatr Congenit Heart Surg. 2016 Nov 23. pii: 2150135116668335. [Epub ahead of print]

  1. Pediatric cardiac readmissions: An opportunity for quality improvement?

Sacks JH, Kelleman M, McCracken C, Glanville M, Oster M.

Congenit Heart Dis. 2016 Nov 22. doi: 10.1111/chd.12436. [Epub ahead of print]

  1. Coarctation repair normalizes left ventricular function and aorto-septal angle in neonates.

Jashari H, Lannering K, Mellander M, Ibrahimi P, Rydberg A, Henein MY.

Congenit Heart Dis. 2016 Nov 22. doi: 10.1111/chd.12430. [Epub ahead of print]

  1. Intra- and inter-reader reproducibility of blood flow measurements on the ascending aorta and pulmonary artery using cardiac magnetic resonance.

Di Leo G, D’Angelo ID, Alì M, Cannaò PM, Mauri G, Secchi F, Sardanelli F.

Radiol Med. 2016 Nov 22. [Epub ahead of print]

  1. The United States Pediatric Cardiology 2015 Workforce Assessment: A Survey of Current Training and Employment Patterns: A Report of the American College of Cardiology, American Heart Association, American Academy of Pediatrics Section on Cardiology and Cardiac Surgery, and Society for Pediatric Cardiology Training Program Directors.

Writing Committee Members., Ross RD, Srivastava S, Cabrera AG, Ruch-Ross HS, Radabaugh CL, Minich LL, Mahle WT, Brown DW.

J Am Coll Cardiol. 2016 Nov 21. pii: S0735-1097(16)36323-9. doi: 10.1016/j.jacc.2016.09.921. [Epub ahead of print] No abstract available.

  1. NT-proBNP as Marker of Ventricular Dilatation and Pulmonary Regurgitation After Surgical Correction of Tetralogy of Fallot: A MRI Validation Study.

Paolino A, Hussain T, Pavon A, Velasco MN, Uribe S, Ordoñez A, Valverde I.

Pediatr Cardiol. 2016 Nov 21. [Epub ahead of print]

  1. Cardiac rehabilitation in an adolescent with Digeorge syndrome: a case report.

Kim DJ, Lee KY, Choe Y, Han JY, Choi IS.

Eur J Phys Rehabil Med. 2016 Nov 18. [Epub ahead of print]

  1. Congenital Variants and Anomalies of the Aortic Arch.

Hanneman K, Newman B, Chan F.

Radiographics. 2016 Nov 18:160033. [Epub ahead of print]

  1. Reducing variation in feeding newborns with congenital heart disease.

Simsic JM, Carpenito KR, Kirchner K, Peters S, Miller-Tate H, Joy B, Galantowicz M.

Congenit Heart Dis. 2016 Nov 16. doi: 10.1111/chd.12435. [Epub ahead of print]

  1. The not so innocent heart murmur: A five year experience.

Kueh SH, Pasley T, Wheeler M, Pemberton J.

Intern Med J. 2016 Nov 16. doi: 10.1111/imj.13331. [Epub ahead of print]

  1. The Use of Nesiritide in Children With Congenital Heart Disease.

Bronicki RA, Domico M, Checchia PA, Kennedy CE, Akcan-Arikan A.

Pediatr Crit Care Med. 2016 Nov 15. [Epub ahead of print]

  1. Analysis of Serum Metabolites to Diagnose Bicuspid Aortic Valve.

Wang W, Maimaiti A, Zhao Y, Zhang L, Tao H, Nian H, Xia L, Kong B, Wang C, Liu M, Wei L.

Sci Rep. 2016 Nov 15;6:37023. doi: 10.1038/srep37023.

  1. Home Exercise Training in Children and Adolescents with Pulmonary Arterial Hypertension: A Pilot Study.

Zöller D, Siaplaouras J, Apitz A, Bride P, Kaestner M, Latus H, Schranz D, Apitz C.

Pediatr Cardiol. 2016 Nov 14. [Epub ahead of print]

  1. Prevalence and pattern of executive dysfunction in school age children with congenital heart disease.

Sanz JH, Berl MM, Armour AC, Wang J, Cheng YI, Donofrio MT.

Congenit Heart Dis. 2016 Nov 11. doi: 10.1111/chd.12427. [Epub ahead of print]

  1. Accelerated ferumoxytol-enhanced 4D multiphase, steady-state imaging with contrast enhancement (MUSIC) cardiovascular MRI: validation in pediatric congenital heart disease.

Zhou Z, Han F, Rapacchi S, Nguyen KL, Brunengraber DZ, Kim GJ, Finn JP, Hu P.

NMR Biomed. 2016 Nov 11. doi: 10.1002/nbm.3663. [Epub ahead of print]

  1. Circulating microRNA as a Novel Biomarker for Pulmonary Arterial Hypertension Due to Congenital Heart Disease.

Chen W, Li S.

Pediatr Cardiol. 2016 Nov 11. [Epub ahead of print]

  1. Utility and Scope of Rapid Prototyping in Patients with Complex Muscular Ventricular Septal Defects or Double-Outlet Right Ventricle: Does it Alter Management Decisions?

Bhatla P, Tretter JT, Ludomirsky A, Argilla M, Latson LA Jr, Chakravarti S, Barker PC, Yoo SJ, McElhinney DB, Wake N, Mosca RS.

Pediatr Cardiol. 2016 Nov 11. [Epub ahead of print]

  1. Pentraxin 3 in neonates with and without diagnosis of pulmonary hypertension.

Farhadi R, Rafiei A, Hamdamian S, Zamani H, Yazdani J.

Clin Biochem. 2016 Nov 10. pii: S0009-9120(16)30528-8. doi: 10.1016/j.clinbiochem.2016.11.009. [Epub ahead of print]

  1. Anomalous left brachiocephalic vein: important vascular anomaly concomitant with congenital anomalies and heart diseases.

Kahkouee S, Sadr M, Pedarzadeh E, Fardin S, Borhani A, Gholami S, Amjad G.

Folia Morphol (Warsz). 2016 Nov 10. doi: 10.5603/FM.a2016.0031. [Epub ahead of print]

  1. A novel, more efficient, staged approach for critical congenital heart disease screening.

Mouledoux J, Guerra S, Ballweg J, Li Y, Walsh W.

J Perinatol. 2016 Nov 10. doi: 10.1038/jp.2016.204. [Epub ahead of print]

  1. Early pulmonary arterial hypertension immediately after closure of a ventricular or complete atrioventricular septal defect beyond 6months of age.

Bambul Heck P, Eicken A, Kasnar-Samprec J, Ewert P, Hager A.

Int J Cardiol. 2016 Nov 9;228:313-318. doi: 10.1016/j.ijcard.2016.11.056. [Epub ahead of print]

  1. Three-dimensional Echocardiography in Congenital Heart Disease: An Expert Consensus Document from the European Association of Cardiovascular Imaging and the American Society of Echocardiography.

Simpson J, Lopez L, Acar P, Friedberg MK, Khoo NS, Helen Ko H, Marek J, Marx G, McGhie JS, Meijboom F, Roberson D, Van den Bosch A, Miller O, Shirali G.

J Am Soc Echocardiogr. 2016 Nov 9. pii: S0894-7317(16)30431-X. doi: 10.1016/j.echo.2016.08.022. [Epub ahead of print]

  1. White Matter Volume Predicts Language Development in Congenital Heart Disease.

Rollins CK, Asaro LA, Akhondi-Asl A, Kussman BD, Rivkin MJ, Bellinger DC, Warfield SK, Wypij D, Newburger JW, Soul JS.

J Pediatr. 2016 Nov 9. pii: S0022-3476(16)31054-X. doi: 10.1016/j.jpeds.2016.09.070. [Epub ahead of print]

  1. Appropriateness and diagnostic yield of inpatient pediatric echocardiograms.

Lang SM, Bolin E, Daily JA, Tang X, Thomas Collins R 2nd.

Congenit Heart Dis. 2016 Nov 8. doi: 10.1111/chd.12428. [Epub ahead of print]

  1. Expanding the clinical spectrum of chromosome 15q26 terminal deletions associated with IGF-1 resistance.

O’Riordan AM, McGrath N, Sharif F, Murphy NP, Franklin O, Lynch SA, O’Grady MJ.

Eur J Pediatr. 2016 Nov 8. [Epub ahead of print]

  1. African-American:White Disparity in Infant Mortality due to Congenital Heart Disease.

Collins JW Jr, Soskolne G, Rankin KM, Ibrahim A, Matoba N.

J Pediatr. 2016 Nov 8. pii: S0022-3476(16)31091-5. doi: 10.1016/j.jpeds.2016.10.023. [Epub ahead of print]

  1. Feasibility and Accuracy of Cardiac Right-to-Left-Shunt Detection in Children by New Transpulmonary Ultrasound Dilution Method.

Boehne M, Baustert M, Paetzel V, Boethig D, Köditz H, Dennhardt N, Beerbaum P, Bertram H.

Pediatr Cardiol. 2016 Nov 8. [Epub ahead of print]

  1. Evaluation of predictive models for six minute walk test among children with pulmonary hypertension.

Patel SS, Fernie JC, Taylor AL, Ivy DD, Rausch CM.

Int J Cardiol. 2016 Nov 7. pii: S0167-5273(16)33488-X. doi: 10.1016/j.ijcard.2016.11.042. [Epub ahead of print]

  1. Congenital Heart Disease in Premature Infants 25-32 Weeks’ Gestational Age.

Chu PY, Li JS, Kosinski AS, Hornik CP, Hill KD.

J Pediatr. 2016 Nov 3. pii: S0022-3476(16)31101-5. doi: 10.1016/j.jpeds.2016.10.033. [Epub ahead of print]

  1. Biomarkers of Myocardial Injury in Congenital Heart Disease: More Questions than Answers.

Chen CA.

Pediatr Neonatol. 2016 Nov 3. pii: S1875-9572(16)30248-0. doi: 10.1016/j.pedneo.2016.10.001. [Epub ahead of print] No abstract available.

  1. A Very Rare Case of Co-Existence of Cor Triatriatum Sinister and Left Pulmonary Vein Atresia.

Aparci M, Yalcin M, Isilak Z, Dogan M, Kardesoglu E.

Acta Cardiol Sin. 2016 Nov;32(6):758-761.

  1. Pulse oximetry could significantly enhance the early detection of critical congenital heart disease in neonatal intensive care units.

Hu XJ, Zhao QM, Ma XJ, Yan WL, Ge XL, Jia B, Liu F, Wu L, Ye M, Huang GY.

Acta Paediatr. 2016 Nov;105(11):e499-e505. doi: 10.1111/apa.13553.

  1. Atypical presentation of infantile-onset farber disease with novel ASAH1 mutations.

Kim SY, Choi SA, Lee S, Lee JS, Hong CR, Lim BC, Kang HJ, Kim KJ, Park SH, Choi M, Chae JH.

Am J Med Genet A. 2016 Nov;170(11):3023-3027. doi: 10.1002/ajmg.a.37846.

  1. Adiposity and Cardiovascular Risk Factor Variables in Childhood Are Associated With Premature Death From Coronary Heart Disease in Adults: The Bogalusa Heart Study.

Berenson GS, Srinivasan SR, Xu JH, Chen W.

Am J Med Sci. 2016 Nov;352(5):448-454. doi: 10.1016/j.amjms.2016.08.006.

  1. Genealogical and molecular analysis of a family-based cohort of congenital heart disease patients from the São Miguel Island (Azores, Portugal).

Cabral R, Pires R, Anjos R, Branco CC, Maciel P, Mota-Vieira L.

Ann Hum Biol. 2016 Nov;43(6):547-553.

  1. Geographic distribution of live births with tetralogy of Fallot in North Carolina 2003 to 2012.

Nelson JS, Stebbins RC, Strassle PD, Meyer RE.

Birth Defects Res A Clin Mol Teratol. 2016 Nov;106(11):881-887. doi: 10.1002/bdra.23566.

  1. Surveillance of ventricular septal defects in Delaware.

Acheson A, Vaidy A, Stomieroski K, Thompson DR, Maiden KM, Ehrenthal DB, Yezdani S, Bhat AM, Locke R, Bartoshesky LE.

Birth Defects Res A Clin Mol Teratol. 2016 Nov;106(11):888-893. doi: 10.1002/bdra.23574.

  1. Current Clinical Applications of Three-Dimensional Echocardiography: When the Technique Makes the Difference.

Surkova E, Muraru D, Aruta P, Romeo G, Bidviene J, Cherata D, Badano LP.

Curr Cardiol Rep. 2016 Nov;18(11):109. doi: 10.1007/s11886-016-0787-9. Review.

  1. Prospective ECG-gated high-pitch dual-source cardiac CT angiography in the diagnosis of congenital cardiovascular abnormalities: Radiation dose and diagnostic efficacy in a pediatric population.

Koplay M, Kizilca O, Cimen D, Sivri M, Erdogan H, Guvenc O, Oc M, Oran B.

Diagn Interv Imaging. 2016 Nov;97(11):1141-1150. doi: 10.1016/j.diii.2016.03.014.

  1. Best practice critical cardiac care in the neonatal unit.

Rigby ML.

Early Hum Dev. 2016 Nov;102:5-11. doi: 10.1016/j.earlhumdev.2016.09.003. Review.

  1. Sildenafil, pulmonary hypertension and bronchopulmonary dysplasia.

Herbert S, Tulloh R.

Early Hum Dev. 2016 Nov;102:21-24. doi: 10.1016/j.earlhumdev.2016.09.009.

  1. ANKS3 is mutated in a family with autosomal recessive laterality defect.

Shamseldin HE, Yakulov TA, Hashem A, Walz G, Alkuraya FS.

Hum Genet. 2016 Nov;135(11):1233-1239.

  1. Rare congenital mitral valve malformations assessed by real-time three-dimensional echocardiography.

Sun F, Chen Y, Huang L, Ren W, Yu X, Ni C.

Int J Cardiol. 2016 Nov 1;222:1027-30. doi: 10.1016/j.ijcard.2016.08.078. No abstract available.

  1. Giant dissecting ventricular septal haematoma associated with critical congenital heart disease.

Suteu CC, Muntean I, Benedek T, Togănel R.

Interact Cardiovasc Thorac Surg. 2016 Nov;23(5):837-838.

  1. Pediatric Echocardiography by Work Relative Value Units: Is Study Complexity Adequately Captured?

Balasubramanian S, Kipps AK, Smith SN, Tacy TA, Selamet Tierney ES.

J Am Soc Echocardiogr. 2016 Nov;29(11):1084-1091. doi: 10.1016/j.echo.2016.05.015.

  1. Infantile (Preductal) Coarctation of Aorta Presenting as Cerebellar Infarct – A Rare Presentation.

Sivaraman A, Kumhar M, Sahu UK, Mali MK.

J Assoc Physicians India. 2016 Nov;64(11):93-94.

  1. Challenges to success in heart failure: Cardiac cell therapies in patients with heart diseases.

Oh H, Ito H, Sano S.

J Cardiol. 2016 Nov;68(5):361-367. doi: 10.1016/j.jjcc.2016.04.010. Review.

  1. Birth defects data from surveillance hospitals in Dalian city, China, 2006-2010.

Liu QG, Sun J, Xiao XW, Song GR.

J Matern Fetal Neonatal Med. 2016 Nov;29(22):3615-21. doi: 10.3109/14767058.2016.1140136.

  1. Brain Dysplasia Associated with Ciliary Dysfunction in Infants with Congenital Heart Disease.

Panigrahy A, Lee V, Ceschin R, Zuccoli G, Beluk N, Khalifa O, Votava-Smith JK, DeBrunner M, Munoz R, Domnina Y, Morell V, Wearden P, Sanchez De Toledo J, Devine W, Zahid M, Lo CW.

J Pediatr. 2016 Nov;178:141-148.e1. doi: 10.1016/j.jpeds.2016.07.041.

  1. Supporting Vulnerable Children after Life-Threatening Neonatal Illness: Opportunities for Improving Outcomes.

Sobotka SA, Msall ME.

J Pediatr. 2016 Nov;178:12-14. doi: 10.1016/j.jpeds.2016.07.037. No abstract available.

  1. School-Age Test Proficiency and Special Education After Congenital Heart Disease Surgery in Infancy.

Mulkey SB, Bai S, Luo C, Cleavenger JE, Gibson N, Holland G, Mosley BS, Kaiser JR, Bhutta AT.

J Pediatr. 2016 Nov;178:47-54.e1. doi: 10.1016/j.jpeds.2016.06.063.

  1. Postoperative Amplitude-Integrated Electroencephalography Predicts Four-Year Neurodevelopmental Outcome in Children with Complex Congenital Heart Disease.

Latal B, Wohlrab G, Brotschi B, Beck I, Knirsch W, Bernet V.

J Pediatr. 2016 Nov;178:55-60.e1. doi: 10.1016/j.jpeds.2016.06.050.

  1. Creating Opportunities for Optimal Nutritional Experiences for Infants With Complex Congenital Heart Disease.

Steltzer MM, Sussman-Karten K, Kuzdeba HB, Mott S, Connor JA.

J Pediatr Health Care. 2016 Nov – Dec;30(6):599-605. doi: 10.1016/j.pedhc.2016.08.002.

  1. The importance of social media for patients and families affected by congenital anomalies: A Facebook cross-sectional analysis and user survey.

Jacobs R, Boyd L, Brennan K, Sinha CK, Giuliani S.

J Pediatr Surg. 2016 Nov;51(11):1766-1771. doi: 10.1016/j.jpedsurg.2016.07.008.

  1. Coronary-Pulmonary Artery Fistulas: A Systematic Review.

Verdini D, Vargas D, Kuo A, Ghoshhajra B, Kim P, Murillo H, Kirsch J, Lane M, Restrepo C.

J Thorac Imaging. 2016 Nov;31(6):380-390.

  1. Impact of postoperative duration of Aspirin use on longevity of bioprosthetic pulmonary valve in patients who underwent congenital heart disease repair.

Hwang TW, Kim SO, Lee SY, Kim SH, Choi EY, Jang SI, Park SJ, Kwon HW, Lim HB, Lee CH, Choi ES.

Korean J Pediatr. 2016 Nov;59(11):446-450.

  1. KinCor, a national registry for paediatric patients with congenital and other types of heart disease in the Netherlands: aims, design and interim results.

Silva LM, Kuipers IM, van den Heuvel F, Mendes R, Berger RM, van Beynum IM, Rozendaal L, Rammeloo LA, van Iperen GG, Schokking M, Frerich S, Blom NA, Breur JM, Helbing WA.

Neth Heart J. 2016 Nov;24(11):628-639.

  1. Improved Survival While Waiting and Risk Factors for Death in Pediatric Patients Listed for Cardiac Transplantation.

Zakaria D, Frazier E, Imamura M, Garcia X, Pye S, Knecht KR, Prodhan P, Gossett JR, Swearingen CJ, Morrow WR.

Pediatr Cardiol. 2016 Nov 1. [Epub ahead of print]

  1. The Utility of Brain Natriuretic Peptide in Pediatric Cardiology: A Review.

Neves AL, Henriques-Coelho T, Leite-Moreira A, Areias JC.

Pediatr Crit Care Med. 2016 Nov;17(11):e529-e538.

  1. Risk factors for pulmonary arterial hypertension in children and young adults.

Naumburg E, Söderström L, Huber D, Axelsson I.

Pediatr Pulmonol. 2016 Nov 1. doi: 10.1002/ppul.23633. [Epub ahead of print]

  1. Effect of the forward-projected model-based iterative reconstruction solution algorithm on image quality and radiation dose in pediatric cardiac computed tomography.

Nishiyama Y, Tada K, Nishiyama Y, Mori H, Maruyama M, Katsube T, Yamamoto N, Kanayama H, Yamamoto Y, Kitagaki H.

Pediatr Radiol. 2016 Nov;46(12):1663-1670.

  1. Delayed cortical gray matter development in neonates with severe congenital heart disease.

Claessens NH, Moeskops P, Buchmann A, Latal B, Knirsch W, Scheer I, Išgum I, de Vries LS, Benders MJ, von Rhein M.

Pediatr Res. 2016 Nov;80(5):668-674. doi: 10.1038/pr.2016.145.

  1. Assessment of cardiac function in absence of congenital and acquired heart disease in patients with Down syndrome.

Balli S, Yucel IK, Kibar AE, Ece I, Dalkiran ES, Candan S.

World J Pediatr. 2016 Nov;12(4):463-469.

  1. Intact Imaging of Human Heart Structure Using X-ray Phase-Contrast Tomography.

Kaneko Y, Shinohara G, Hoshino M, Morishita H, Morita K, Oshima Y, Takahashi M, Yagi N, Okita Y, Tsukube T.

Pediatr Cardiol. 2016 Nov 30. [Epub ahead of print]

  1. Left Ventricular Function in Healthy Term Neonates During the Transitional Period.

Jain A, El-Khuffash AF, Kuipers BC, Mohamed A, Connelly KA, McNamara PJ, Jankov RP, Mertens L.

J Pediatr. 2016 Nov 28. pii: S0022-3476(16)31231-8. doi: 10.1016/j.jpeds.2016.11.003. [Epub ahead of print]

  1. Assessment of copy number variations in 120 patients with Poland syndrome.

Vaccari CM, Tassano E, Torre M, Gimelli S, Divizia MT, Romanini MV, Bossi S, Musante I, Valle M, Senes F, Catena N, Bedeschi MF, Baban A, Calevo MG, Acquaviva M, Lerone M, Ravazzolo R, Puliti A.

BMC Med Genet. 2016 Nov 25;17(1):89.

  1. Morphological Assessment of Single-Ventricle Atrioventricular Valve Regurgitation on Dual-Source 128-Slice Multidetector Computed Tomography and 4-Dimensional Imaging.

Kodama Y, Nakamura M, Sagawa K, Ishikawa S, Nakano T, Kado H.

Circ J. 2016 Nov 25;80(12):2555-2556. No abstract available.

  1. Limited Ventricular Preload is the Main Reason for Reduced Stress Reserve After Atrial Baffle Repair.

Eicken A, Michel J, Hager A, Tanase D, Kaemmerer H, Cleuziou J, Hess J, Ewert P.

Pediatr Cardiol. 2016 Nov 24. [Epub ahead of print]

  1. Finding Harmony between Science and Art in Pediatric Cardiology: Acknowledging When Being “Objective” May Not Truly Be Objective.

Loomba RS.

Children (Basel). 2016 Nov 23;3(4). pii: E37.

  1. Oscillometric and auscultatory blood pressure measurement methods in children: a systematic review and meta-analysis.

Duncombe SL, Voss C, Harris KC.

J Hypertens. 2016 Nov 23. [Epub ahead of print]

  1. Difference in Risk Factors for Subtypes of Acute Cardiac Lesions Resulting from Kawasaki Disease.

Yamashita M, Ae R, Yashiro M, Aoyama Y, Sano T, Makino N, Nakamura Y.

Pediatr Cardiol. 2016 Nov 23. [Epub ahead of print]

  1. Global Deformation Parameters Response to Exercise in Adolescents with Repaired Tetralogy of Fallot.

Mese T, Guven B, Yilmazer MM, Demirol M, Çoban Ş, Karadeniz C.

Pediatr Cardiol. 2016 Nov 23. [Epub ahead of print]

  1. Gender dimorphism in pediatric OSA: Is it for real?

Brockmann PE, Koren D, Kheirandish-Gozal L, Gozal D.

Respir Physiol Neurobiol. 2016 Nov 23. pii: S1569-9048(16)30223-3. doi: 10.1016/j.resp.2016.11.010. [Epub ahead of print] Review.

  1. Genetic Variation in the SLC8A1 Calcium Signaling Pathway Is Associated with Susceptibility to Kawasaki Disease and Coronary Artery Abnormalities.

Shimizu C, Eleftherohorinou H, Wright VJ, Kim J, Alphonse MP, Perry JC, Cimaz R, Burgner D, Dahdah N, Hoang LT, Khor CC, Salgado A, Tremoulet AH, Davila S, Kuijpers TW, Hibberd ML, Johnson TA, Takahashi A, Tsunoda T, Kubo M, Tanaka T, Onouchi Y, Yeung RS, Coin LJ, Levin M, Burns JC.

Circ Cardiovasc Genet. 2016 Nov 21. pii: CIRCGENETICS.116.001533. [Epub ahead of print]

  1. Experimental, Systems and Computational Approaches to Understanding the MicroRNA-Mediated Reparative Potential of Cardiac Progenitor Cell-Derived Exosomes From Pediatric Patients.

Agarwal U, George A, Bhutani S, Ghosh-Choudhary S, Maxwell JT, Brown ME, Mehta Y, Platt MO, Liang Y, Sahoo S, Davis ME.

Circ Res. 2016 Nov 21. pii: CIRCRESAHA.116.309935. [Epub ahead of print]

  1. Transcriptional Analysis of Intravenous Immunoglobulin Resistance in Kawasaki Disease Using an Induced Pluripotent Stem Cell Disease Model.

Ikeda K, Mizoro Y, Ameku T, Nomiya Y, Mae SI, Matsui S, Kuchitsu Y, Suzuki C, Hamaoka-Okamoto A, Yahata T, Sone M, Okita K, Watanabe A, Osafune K, Hamaoka K.

Circ J. 2016 Nov 19. [Epub ahead of print]

  1. Intellectual Functioning in Children with Congenital Heart Defects Treated with Surgery or by Catheter Interventions.

Ryberg C, Sunnegårdh J, Thorson M, Broberg M.

Front Pediatr. 2016 Nov 17;4:113.

  1. Prevalence of congenital coronary artery anomalies as shown by multi-slice computed tomography coronary angiography: a single-centre study from Turkey.

Tongut A, Özyedek Z, Çerezci İ, Erentürk S, Hatemi AC.

J Int Med Res. 2016 Nov 17. pii: 0300060516667118. [Epub ahead of print]

  1. Effect of Release of the First Pediatric Appropriate Use Criteria on Transthoracic Echocardiogram Ordering Practice.

Sachdeva R, Douglas PS, Kelleman MS, McCracken CE, Lopez L, Stern KW, Eidem BW, Benavidez OJ, Weiner RB, Welch E, Campbell RM, Lai WW.

Am J Cardiol. 2016 Nov 15;118(10):1545-1551. doi: 10.1016/j.amjcard.2016.08.019.

  1. Hepatoma-derived Growth Factor Predicts Disease Severity and Survival in Pulmonary Arterial Hypertension.

Yang J, Nies MK, Fu Z, Damico R, Korley FK, Hassoun PM, Ivy DD, Austin ED, Everett AD.

Am J Respir Crit Care Med. 2016 Nov 15;194(10):1264-1272.

  1. Corrigendum to “FUTURE-2: Results from an open-label, long-term safety and tolerability extension study using the pediatric FormUlation of bosenTan in pUlmonary arterial hypeRtEnsion” [Int. J. Cardiol. 202 (2016) 52-58].

Berger RM, Haworth SG, Bonnet D, Dulac Y, Fraisse A, Galiè N, Ivy DD, Jaïs X, Miera O, Rosenzweig EB, Efficace M, Kusic-Pajic A, Beghetti M.

Int J Cardiol. 2016 Nov 15;223:1072-1073. doi: 10.1016/j.ijcard.2016.08.333. No abstract available.

  1. Ebstein’s anomaly and aortic arch lesions: When right meets left.

Geerdink LM, Ter Heide H, Kapusta L.

Int J Cardiol. 2016 Nov 15;223:568-570. doi: 10.1016/j.ijcard.2016.08.181. No abstract available.

  1. A singular case of non-obstructive supracardiac total anomalous pulmonary venous connection with two vertical veins in a 30weeks preterm neonate.

Figueras-Coll M, Sabaté-Rotés A, Cañete-Abajo N, Abella RF.

Int J Cardiol. 2016 Nov 15;223:50-51. doi: 10.1016/j.ijcard.2016.08.047. No abstract available.

  1. A rare cause of cardiomyopathy in an infant: middle aortic syndrome.

Mir A, Stam B, Sperrazza C.

Cardiol Young. 2016 Nov 14:1-3. [Epub ahead of print]

  1. Impact of sickle cell anaemia on cardiac chamber size in the paediatric population.

Adjagba PM, Habib G, Robitaille N, Pastore Y, Raboisson MJ, Curnier D, Dahdah N.

Cardiol Young. 2016 Nov 14:1-7. [Epub ahead of print]

  1. Accelerated ferumoxytol-enhanced 4D multiphase, steady-state imaging with contrast enhancement (MUSIC) cardiovascular MRI: validation in pediatric congenital heart disease.

Zhou Z, Han F, Rapacchi S, Nguyen KL, Brunengraber DZ, Kim GJ, Finn JP, Hu P.

NMR Biomed. 2016 Nov 11. doi: 10.1002/nbm.3663. [Epub ahead of print]

  1. Circulating microRNA as a Novel Biomarker for Pulmonary Arterial Hypertension Due to Congenital Heart Disease.

Chen W, Li S.

Pediatr Cardiol. 2016 Nov 11. [Epub ahead of print]

  1. Longitudinal Validation of the Diastolic to Systolic Time-Velocity Integral Ratio as a Doppler-Derived Measure of Pulmonary Regurgitation in Patients with Repaired Tetralogy of Fallot.

Bhat M, Goldmuntz E, Fogel MA, Rychik J, Mercer-Rosa L.

Pediatr Cardiol. 2016 Nov 11. [Epub ahead of print]

  1. Evaluation of Residual Coarctation in Infants with a Single Right Ventricle after Stage I Palliation.

Fundora MP, Sasaki J, Muniz JC, Rossi A, Rhodes JF Jr, Hannan RL, Burke RP, Lopez L.

Pediatr Cardiol. 2016 Nov 11. [Epub ahead of print]

  1. Galectin-3 in Children with Chronic Heart Failure with Normal and Reduced Ejection Fraction: Relationship to Disease Severity.

Kotby AA, Youssef OI, Elmaraghy MO, El Sharkawy OS.

Pediatr Cardiol. 2016 Nov 11. [Epub ahead of print]

  1. Influence of apical position on the left ventricular outflow tract obstruction in congenitally corrected transposition.

Lee ML, Chiu IS.

J Cardiol. 2016 Nov 10. pii: S0914-5087(16)30173-3. doi: 10.1016/j.jjcc.2016.07.019. [Epub ahead of print]

  1. Late Wall Thickening and Calcification in Patients After Kawasaki Disease.

Tsujii N, Tsuda E, Kanzaki S, Ishizuka J, Nakashima K, Kurosaki K.

J Pediatr. 2016 Nov 10. pii: S0022-3476(16)31094-0. doi: 10.1016/j.jpeds.2016.10.026. [Epub ahead of print]

  1. Neurologic, Neurocognitive and Functional Outcomes in Children Under 6 Years Treated with The Berlin Heart Excor Ventricular Assist Device.

VanderPluym JH, Robertson CM, Joffe AR, Conway J, Rebeyka IM, Ross DB, Guerra GG, Al Aklabi MM, Buchholz H.

ASAIO J. 2016 Nov 9. [Epub ahead of print]

  1. Usefulness of soluble urokinase plasminogen activator receptor (suPAR) as an inflammatory biomarker in obese children.

Kosecik M, Dervisoglu P, Koroglu M, Isguven P, Elmas B, Demiray T, Altindis M.

Int J Cardiol. 2016 Nov 9;228:158-161. doi: 10.1016/j.ijcard.2016.11.201. [Epub ahead of print]

  1. Appropriateness and diagnostic yield of inpatient pediatric echocardiograms.

Lang SM, Bolin E, Daily JA, Tang X, Thomas Collins R 2nd.

Congenit Heart Dis. 2016 Nov 8. doi: 10.1111/chd.12428. [Epub ahead of print]

  1. Safety of Enalapril in Infants Admitted to the Neonatal Intensive Care Unit.

Ku LC, Zimmerman K, Benjamin DK, Clark RH, Hornik CP, Smith PB; Best Pharmaceuticals for Children Act – Pediatric Trials Network Steering Committee..

Pediatr Cardiol. 2016 Nov 8. [Epub ahead of print]

  1. The Action of Smooth Muscle Cell Potassium Channels in the Pathology of Pulmonary Arterial Hypertension.

Hayabuchi Y.

Pediatr Cardiol. 2016 Nov 8. [Epub ahead of print] Review.

  1. Diagnostic Yield of Outpatient Pediatric Echocardiograms: Impact of Indications and Specialty.

Lang SM, Bolin E, Hardy S, Tang X, Collins RT 2nd.

Pediatr Cardiol. 2016 Nov 8. [Epub ahead of print]

  1. Right aortic arch with isolation of the left subclavian artery: a rare association with airway obstruction.

Yubbu P, Latiff HA, Adam Abbaker AM.

Cardiol Young. 2016 Nov 7:1-4. [Epub ahead of print]

  1. Assessment of early atherosclerosis and left ventricular dysfunction in children with 21-hydroxylase deficiency.

Özdemir R, Korkmaz HA, Küçük M, Karadeniz C, Meşe T, Özkan B.

Clin Endocrinol (Oxf). 2016 Nov 7. doi: 10.1111/cen.13275. [Epub ahead of print]

  1. Racial Differences in Aortic Stiffness in Children.

Lefferts WK, Augustine JA, Spartano NL, Atallah-Yunes NH, Heffernan KS, Gump BB.

J Pediatr. 2016 Nov 3. pii: S0022-3476(16)31055-1. doi: 10.1016/j.jpeds.2016.09.071. [Epub ahead of print]

  1. Echocardiographic Follow-Up of Patent Foramen Ovale and the Factors Affecting Spontaneous Closure.

Yildirim A, Aydin A, Demir T, Aydin F, Ucar B, Kilic Z.

Acta Cardiol Sin. 2016 Nov;32(6):731-737.

  1. Student perceptions of a video-based blended learning approach for improving pediatric physical examination skills.

Lehmann R, Seitz A, Bosse HM, Lutz T, Huwendiek S.

Ann Anat. 2016 Nov;208:179-182. doi: 10.1016/j.aanat.2016.05.009.

  1. Characteristics and outcomes of Indian children enrolled in a rheumatic heart disease registry.

Mehta A, Saxena A, Juneja R, Ramakrishnan S, Gupta S, Kothari SS.

Int J Cardiol. 2016 Nov 1;222:1136-40. doi: 10.1016/j.ijcard.2016.08.259.

  1. Inflammatory myofibroblastic tumor of the left atrium in infant.

Bao M, Zheng C, Zhang H, Ruan Y, Cao A, Wu T, Luo YI.

Int J Cardiol. 2016 Nov 1;222:965-7. doi: 10.1016/j.ijcard.2016.08.029. No abstract available.

  1. Pediatric Echocardiography by Work Relative Value Units: Is Study Complexity Adequately Captured?

Balasubramanian S, Kipps AK, Smith SN, Tacy TA, Selamet Tierney ES.

J Am Soc Echocardiogr. 2016 Nov;29(11):1084-1091. doi: 10.1016/j.echo.2016.05.015.

  1. Cardiovascular magnetic resonance is successfully feasible in many patients aged 3 to 8years without general anesthesia or sedation.

Kharabish A, Mkrtchyan N, Meierhofer C, Martinoff S, Ewert P, Stern H, Fratz S.

J Clin Anesth. 2016 Nov;34:11-4. doi: 10.1016/j.jclinane.2016.02.048.

  1. Disease control via intensified lipoprotein apheresis in three siblings with familial hypercholesterolemia.

Taylan C, Schlune A, Meissner T, Ažukaitis K, Udink Ten Cate FE, Weber LT.

J Clin Lipidol. 2016 Nov – Dec;10(6):1303-1310. doi: 10.1016/j.jacl.2016.08.006.

  1. Correlates of Achieving Statin Therapy Goals in Children and Adolescents with Dyslipidemia.

Mendelson MM, Regh T, Chan J, Baker A, Ryan HH, Palumbo N, Johnson PK, Griggs S, Boghani M, Desai NK, Yellen E, Buckley L, Gillman MW, Zachariah JP, Graham D, de Ferranti SD.

J Pediatr. 2016 Nov;178:149-155.e9. doi: 10.1016/j.jpeds.2016.08.003.

  1. Referral Patterns and Cascade Screening for Familial Hypercholesterolemia in a Pediatric Lipid Clinic.

Stempel H, Dodge A, Marriott E, Peterson AL.

J Pediatr. 2016 Nov;178:285-287. doi: 10.1016/j.jpeds.2016.08.016.

  1. Hypercalcemia in Patients with Williams-Beuren Syndrome.

Sindhar S, Lugo M, Levin MD, Danback JR, Brink BD, Yu E, Dietzen DJ, Clark AL, Purgert CA, Waxler JL, Elder RW, Pober BR, Kozel BA.

J Pediatr. 2016 Nov;178:254-260.e4. doi: 10.1016/j.jpeds.2016.08.027.

  1. Parameters indicative of persistence of valvular pathology at initial diagnosis in acute rheumatic carditis: the role of albumin and CD19 expression.

Oner T, Ozdemir R, Genc DB, Kucuk M, Karadeniz C, Demirpence S, Yilmazer MM, Mese T, Tavli V, Genel F.

J Pediatr (Rio J). 2016 Nov – Dec;92(6):581-587. doi: 10.1016/j.jped.2016.01.013.

  1. The state of point-of-care ultrasonography use and training in neonatal-perinatal medicine and pediatric critical care medicine fellowship programs.

Nguyen J, Amirnovin R, Ramanathan R, Noori S.

J Perinatol. 2016 Nov;36(11):972-976. doi: 10.1038/jp.2016.126.

  1. Decision analysis to define the optimal management of athletes with anomalous aortic origin of a coronary artery.

Mery CM, Lopez KN, Molossi S, Sexson-Tejtel SK, Krishnamurthy R, McKenzie ED, Fraser CD Jr, Cantor SB.

J Thorac Cardiovasc Surg. 2016 Nov;152(5):1366-1375.e7. doi: 10.1016/j.jtcvs.2016.07.076.

  1. Near-infrared spectroscopy for detection of a significant patent ductus arteriosus.

Chock VY, Rose LA, Mante JV, Punn R.

Pediatr Res. 2016 Nov;80(5):675-680. doi: 10.1038/pr.2016.148.

  1. New-onset diabetes mellitus after heart transplantation in children – Incidence and risk factors.

Sehgal S, Bock MJ, Louks Palac H, Brickman WJ, Gossett JG, Marino BS, Backer CL, Pahl E.

Pediatr Transplant. 2016 Nov;20(7):963-969. doi: 10.1111/petr.12759.

  1. Isolated Subclavian Artery: A Rare Entity Revisited.

Sen S, Mohanty S, Kulkarni S, Rao SG.

World J Pediatr Congenit Heart Surg. 2016 Nov;7(6):744-749.

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