CHD Surgery Featured Articles of March 2017

CHD Surgery March 2017

 

  1. Acute kidney injury and fluid overload in infants and children after cardiac surgery.

Kwiatkowski DM, Krawczeski CD.

Pediatr Nephrol. 2017 Mar 30. doi: 10.1007/s00467-017-3643-2. [Epub ahead of print]

PMID:

 

28361230

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Select item 28370416 88.

 

  1. Significant survival advantage of high pulmonary vein index and the presence of native pulmonary artery in pulmonary atresia with ventricular septal defect and major aortopulmonary collateral arteries: results from preoperative computed tomography angiography.

Jia Q, Cen J, Zhuang J, Zhong X, Liu X, Li J, Liang C, Huang M.

Eur J Cardiothorac Surg. 2017 Mar 28. doi: 10.1093/ejcts/ezx064. [Epub ahead of print]

PMID:

 

28369397

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Select item 28369475 90.

 

  1. National trends and variability in blood utilization in paediatric cardiac surgery.

Karimi M, Sullivan JM, Lerer T, Hronek C.

Interact Cardiovasc Thorac Surg. 2017 Mar 28. doi: 10.1093/icvts/ivw439. [Epub ahead of print]

PMID:

 

28369475

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Select item 28335833 91.

 

  1. Dehiscence of a pulmonary bioprosthesis with a focal dissection of the pulmonary artery in a patient withcongenitalpulmonic stenosis.

Yucel E, Bhatt A, Mihos CG, Ghoshhajra BB, DeFaria Yeh D.

Echocardiography. 2017 Mar 27. doi: 10.1111/echo.13502. [Epub ahead of print]

PMID:

 

28345243

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Select item 28346832 94.

 

  1. Surgical planning for a complex double-outlet right ventricle using 3D printing.

Bhatla P, Tretter JT, Chikkabyrappa S, Chakravarti S, Mosca RS.

Echocardiography. 2017 Mar 19. doi: 10.1111/echo.13512. [Epub ahead of print]

PMID:

 

28317159

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Select item 28316101 114.

 

  1. Near-infrared spectroscopy as a predictor of clinical deterioration: a case report of two infants with duct-dependentcongenital heart disease.

Mebius MJ, Sarvaas GJ, Wolthuis DW, Bartelds B, Kneyber MC, Bos AF, Kooi EM.

BMC Pediatr. 2017 Mar 16;17(1):79. doi: 10.1186/s12887-017-0839-3.

PMID:

 

28302079

Free PMC Article

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Select item 28302752 132.

 

  1. Anesthesia in adults withcongenital heart disease.

Baehner T, Ellerkmann RK.

Curr Opin Anaesthesiol. 2017 Mar 16. doi: 10.1097/ACO.0000000000000468. [Epub ahead of print]

PMID:

 

28306681

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Select item 28302684 136.

 

  1. Incorporating Comorbidity Within Risk Adjustment for UK Pediatric Cardiac Surgery.

Brown KL, Rogers L, Barron DJ, Tsang V, Anderson D, Tibby S, Witter T, Stickley J, Crowe S, English K, Franklin RC, Pagel C.

Ann Thorac Surg. 2017 Mar 15. pii: S0003-4975(16)31826-4. doi: 10.1016/j.athoracsur.2016.12.013. [Epub ahead of print]

PMID:

 

28318514

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Select item 28318513 143.

 

  1. Improving Risk Adjustment for Mortality After Pediatric Cardiac Surgery: The UK PRAiS2 Model.

Rogers L, Brown KL, Franklin RC, Ambler G, Anderson D, Barron DJ, Crowe S, English K, Stickley J, Tibby S, Tsang V, Utley M, Witter T, Pagel C.

Ann Thorac Surg. 2017 Mar 15. pii: S0003-4975(16)31828-8. doi: 10.1016/j.athoracsur.2016.12.014. [Epub ahead of print]

PMID:

 

28318513

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Select item 28296217 144.

 

  1. Mechanical and microstructural analysis of a radially expandable vascular conduit for neonatal and pediatric cardiovascular surgery.

Loneker AE, Luketich SK, Bernstein D, Kalra A, Nugent AW, D’Amore A, Faulk DM.

J Biomed Mater Res B Appl Biomater. 2017 Mar 10. doi: 10.1002/jbm.b.33874. [Epub ahead of print]

PMID:

 

28296198

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Select item 28283918 169.

 

  1. Decellularized Cryopreserved Allografts as Off-the-Shelf Allogeneic Alternative forHeartValve Replacement: In Vitro Assessment Before Clinical Translation.

Iop L, Paolin A, Aguiari P, Trojan D, Cogliati E, Gerosa G.

J Cardiovasc Transl Res. 2017 Mar 9. doi: 10.1007/s12265-017-9738-0. [Epub ahead of print]

PMID:

 

28281241

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Select item 28281240 180

 

  1. Translational Challenges in Cardiovascular Tissue Engineering.

Emmert MY, Fioretta ES, Hoerstrup SP.

J Cardiovasc Transl Res. 2017 Mar 9. doi: 10.1007/s12265-017-9728-2. [Epub ahead of print]

PMID:

 

28281240

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Select item 28285866 181.

 

  1. Single coronary artery and neonatal arterial switch operation: early and long-term outcomes†.

Gerelli S, Pontailler M, Rochas B, Angeli E, Van Steenberghe M, Bonnet D, Vouhé P, Raisky O.

Eur J Cardiothorac Surg. 2017 Mar 7. doi: 10.1093/ejcts/ezx046. [Epub ahead of print]

PMID:

 

28329313

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Select item 28371698 190.

 

  1. Contemporary cardiac surgery for adults withcongenital heart disease.

Beurtheret S, Tutarel O, Diller GP, West C, Ntalarizou E, Resseguier N, Papaioannou V, Jabbour R, Simpkin V, Bastin AJ, Babu-Narayan SV, Bonello B, Li W, Sethia B, Uemura H, Gatzoulis MA, Shore D.

Heart. 2017 Mar 7. pii: heartjnl-2016-310384. doi: 10.1136/heartjnl-2016-310384. [Epub ahead of print]

PMID:

 

28270427

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Select item 28270426 193.

 

  1. Outcomes following implantation of mechanical circulatory support in adults withcongenital heart disease: An analysis of the Interagency Registry for Mechanically Assisted Circulatory Support (INTERMACS).

VanderPluym CJ, Cedars A, Eghtesady P, Maxwell BG, Gelow JM, Burchill LJ, Maltais S, Koehl DA, Cantor RS, Blume ED.

Heart Lung Transplant. 2017 Mar 7. pii: S1053-2498(17)31682-0. doi: 10.1016/j.healun.2017.03.005. [Epub ahead of print]

PMID:

 

28365175

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Select item 28283462 196.

 

  1. Prophylactic levosimendan for the prevention of low cardiac output syndrome and mortality in paediatric patients undergoing surgery forcongenital heart disease.

Hummel J, Rücker G, Stiller B.

Cochrane Database Syst Rev. 2017 Mar 6;3:CD011312. doi: 10.1002/14651858.CD011312.pub2. Review.

PMID:

 

28262914

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Select item 28329155 200.

 

  1. Popular HybridCongenitalHeart Procedures without Cardiopulmonary Bypass.

Gupta A, Amin Z.

Front Surg. 2017 Mar 6;4:9. doi: 10.3389/fsurg.2017.00009. eCollection 2017. Review.

PMID:

 

28321396

Free PMC Article

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Select item 28372885 202.

 

  1. Long-term survival after the Fontan operation: Twenty years of experience at a single center.

Downing TE, Allen KY, Glatz AC, Rogers LS, Ravishankar C, Rychik J, Faerber JA, Fuller S, Montenegro LM, Steven JM, Spray TL, Nicolson SC, Gaynor JW, Goldberg DJ.

J Thorac Cardiovasc Surg. 2017 Mar 6. pii: S0022-5223(17)30373-2. doi: 10.1016/j.jtcvs.2017.01.056. [Epub ahead of print]

PMID:

 

28341469

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Select item 28262061 207.

 

  1. Improved long-term outcomes in double-inlet left ventricle and tricuspid atresia with transposed great arteries: systemic outflow tract obstruction present at birth defines long-term outcome.

Franken LC, Admiraal M, Verrall CE, Zannino D, Ayer JG, Iyengar AJ, Cole AD, Sholler GF, D’Udekem Y, Winlaw DS.

Eur J Cardiothorac Surg. 2017 Mar 4. doi: 10.1093/ejcts/ezx022. [Epub ahead of print]

PMID:

 

28329058

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Select item 28259844 211.

 

  1. Successful cardiac transplantation outcomes in patients with adultcongenital heart disease.

Menachem JN, Golbus JR, Molina M, Mazurek JA, Hornsby N, Atluri P, Fuller S, Birati EY, Kim YY, Goldberg LR, Wald JW.

Heart. 2017 Mar 3. pii: heartjnl-2016-310933. doi: 10.1136/heartjnl-2016-310933. [Epub ahead of print]

PMID:

 

28258242

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Select item 28057753 217.

 

  1. Long-Term Outcome of Patients With Complete Atrioventricular Septal Defect Combined With the Tetralogy of Fallot: Staged Repair Is Not Inferior to Primary Repair.

Vitanova K, Cleuziou J, Schreiber C, Günther T, Pabst von Ohain J, Hörer J, Lange R.

Ann Thorac Surg. 2017 Mar;103(3):876-880. doi: 10.1016/j.athoracsur.2016.07.038. Epub 2016 Sep 28.

PMID:

 

27692233

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Select item 28034627 228.

 

  1. Two-dimensional right ventricular strain by speckle tracking for assessment of longitudinal right ventricular function after paediatriccongenital heart diseasesurgery.

Karsenty C, Hadeed K, Dulac Y, Semet F, Alacoque X, Breinig S, Leobon B, Acar P, Hascoet S.

Arch Cardiovasc Dis. 2017 Mar;110(3):157-166. doi: 10.1016/j.acvd.2016.09.003. Epub 2016 Dec 27.

PMID:

 

28034627

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Select item 28261286 229.

 

  1. Health-related quality of life in children with surgery for CHD: a study from the Swedish National Registry forCongenital Heart Disease.

Svensson B, Idvall E, Nilsson F, Liuba P.

Cardiol Young. 2017 Mar;27(2):333-343. doi: 10.1017/S1047951116000585. Epub 2016 May 26.

PMID:

 

27225489

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Select item 27194079 236.

 

  1. Alterations in antioxidant and oxidant status of children after on-pump surgery for cyanotic and acyanoticcongenitalheart diseases.

Altin FH, Yildirim HA, Tanidir IC, Yildiz O, Kahraman MZ, Ozturk E, Celebi SB, Kyaruzi M, Bakir İ.

Cardiol Young. 2017 Mar;27(2):325-332. doi: 10.1017/S1047951116000573. Epub 2016 May 19.

PMID:

 

27194079

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Select item 27125662 237.

 

  1. Clinical significance of serum cortisol levels following surgery forcongenital heart disease.

Teagarden AM, Mastropietro CW.

Cardiol Young. 2017 Mar;27(2):318-324. doi: 10.1017/S104795111600055X. Epub 2016 Apr 29.

PMID:

 

27125662

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Select item 27055357 238.

 

  1. Hydrodynamic Assessment of Aortic Valves Prepared from Porcine Small Intestinal Submucosa.

Ramaswamy S, Lordeus M, Mankame OV, Valdes-Cruz L, Bibevski S, Bell SM, Baez I, Scholl F.

Cardiovasc Eng Technol. 2017 Mar;8(1):30-40. doi: 10.1007/s13239-016-0290-x. Epub 2016 Dec 19.

PMID:

 

27995570

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Select item 28171828 240.

 

  1. Single-center outcomes of combinedheartand liver transplantation in the failing Fontan.

D’Souza BA, Fuller S, Gleason LP, Hornsby N, Wald J, Krok K, Shaked A, Goldberg LR, Pochettino A, Olthoff KM, Kim YY.

Clin Transplant. 2017 Mar;31(3). doi: 10.1111/ctr.12892. Epub 2017 Feb 4.

PMID:

 

27988989

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Select item 27793968 252.

 

  1. Decreased biventricular longitudinal strain shortly aftercongenitalheart defect surgery.

de Boer JM, Kuipers IM, Klitsie LM, Blom NA, Ten Harkel AD.

Echocardiography. 2017 Mar;34(3):446-452. doi: 10.1111/echo.13456. Epub 2017 Feb 6.

PMID:

 

28168740

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Select item 28052532 258.

 

  1. Systemic right ventricular morphology in the early postoperative course after extracardiac Fontan operation: is there still a need for special care?

Nordmeyer S, Rohder M, Nordmeyer J, Miera O, Peters B, Cho MY, Photiadis J, Berger F, Ovroutski S.

Eur J Cardiothorac Surg. 2017 Mar 1;51(3):483-489. doi: 10.1093/ejcts/ezw374.

PMID:

 

28007868

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Select item 28007608 265.

 

  1. Glial fibrillary acidic protein plasma levels are correlated with degree of hypothermia during cardiopulmonary bypass incongenital heart diseasesurgery.

Vedovelli L, Padalino M, D’Aronco S, Stellin G, Ori C, Carnielli VP, Simonato M, Cogo P.

Interact Cardiovasc Thorac Surg. 2017 Mar 1;24(3):436-442. doi: 10.1093/icvts/ivw395.

PMID:

 

28040762

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Select item 28270645 278.

 

  1. Surgical management of double outlet right ventricle with aortopulmonary window.

Hou C, Sihag V, Ling Y, An Q.

J Card Surg. 2017 Mar;32(3):203-205. doi: 10.1111/jocs.13102.

PMID:

 

28247470

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Select item 28229912 282.

 

  1. Extubation Failure after Neonatal Cardiac Surgery: A Multicenter Analysis.

Mastropietro CW, Cashen K, Grimaldi LM, Narayana Gowda KM, Piggott KD, Wilhelm M, Gradidge E, Moser EA, Benneyworth BD, Costello JM.

J Pediatr. 2017 Mar;182:190-196.e4. doi: 10.1016/j.jpeds.2016.12.028. Epub 2017 Jan 4.

PMID:

 

28063686

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Select item 27916446 290.

 

  1. Gastrointestinal complications associated with the surgical treatment ofheartdiseasein children.

Ferguson LP, Gandiya T, Kaselas C, Sheth J, Hasan A, Gabra HO.

J Pediatr Surg. 2017 Mar;52(3):414-419. doi: 10.1016/j.jpedsurg.2016.10.052. Epub 2016 Nov 14.

PMID:

 

27916446

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Select item 27894758 291.

 

  1. The impact of cardiac risk factors on short-term outcomes for children undergoing a Ladd procedure.

Putnam LR, Anderson KT, Tsao K, Kao LS, Lugo JA, Lally KP, Kawaguchi AL.

J Pediatr Surg. 2017 Mar;52(3):390-394. doi: 10.1016/j.jpedsurg.2016.09.064. Epub 2016 Oct 21.

PMID:

 

27894758

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Select item 27831548 292.

 

  1. Natural history of nonimmune-mediated thrombocytopenia and acute kidney injury in pediatric open-heartsurgery.

Tew S, Fontes ML, Greene NH, Kertai MD, Ofori-Amanfo G, Jaquiss RD, Lodge AJ, Ames WA, Homi HM, Machovec KA, Jooste EH.

Paediatr Anaesth. 2017 Mar;27(3):305-313. doi: 10.1111/pan.13063. Epub 2017 Jan 18.

PMID:

 

28098429

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Select item 28029591 303.

 

  1. Prevalence and Risk Factors for Pericardial Effusions Requiring Readmission After Pediatric Cardiac Surgery.

Elias MD, Glatz AC, O’Connor MJ, Schachtner S, Ravishankar C, Mascio CE, Cohen MS.

Pediatr Cardiol. 2017 Mar;38(3):484-494. doi: 10.1007/s00246-016-1540-2. Epub 2016 Nov 30.

PMID:

 

27900408

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Select item 27878634 315.

 

  1. Perioperative Near-Infrared Spectroscopy Monitoring in Neonates WithCongenital Heart Disease: Relationship of Cerebral Tissue Oxygenation Index Variability With Neurodevelopmental Outcome.

Spaeder MC, Klugman D, Skurow-Todd K, Glass P, Jonas RA, Donofrio MT.

Pediatr Crit Care Med. 2017 Mar;18(3):213-218. doi: 10.1097/PCC.0000000000001056.

PMID:

 

28067688

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Select item 28326958 318.

 

  1. Left Ventricular Retraining and Double Switch in Patients With Congenitally Corrected Transposition of the Great Arteries.

Ibrahimiye AN, Mainwaring RD, Patrick WL, Downey L, Yarlagadda V, Hanley FL.

World J Pediatr Congenit Heart Surg. 2017 Mar;8(2):203-209. doi: 10.1177/2150135116683939.

PMID:

 

28329464

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Select item 28329459 330.

 

  1. Nineteen Years of AdultCongenitalHeart Surgery in a Single Center.

Perinpanayagam M, Larsen SH, Emmertsen K, Møller MB, Hjortdal VE.

World J Pediatr Congenit Heart Surg. 2017 Mar;8(2):182-188. doi: 10.1177/2150135116682454.

PMID:

 

28329459

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Select item 28329458 331.

 

  1. Hemolysis During Open-HeartSurgery With Vacuum-Assisted Venous Drainage at Different Negative Pressures in Pediatric Patients Weighing Less Than 10 kilograms.

Kwak JG, Lee J, Park M, Seo YJ, Lee CH.

World J Pediatr Congenit Heart Surg. 2017 Mar;8(2):161-165. doi: 10.1177/2150135116681734.

PMID:

 

28329457

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Select item 28329454 333.

 

  1. Anomalous Pulmonary Venous Connection With an Intraparenchymal Course.

Campanale CM, Banka P, Sanders SP.

World J Pediatr Congenit Heart Surg. 2017 Mar;8(2):210-214. doi: 10.1177/2150135116682468. Epub 2016 Dec 30.

PMID:

 

28036230

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Select item 27927943 336.

 

  1. Superior Vena Cava Banding to Facilitate Unilateral Bidirectional Glenn Operation in Patients With Single VentricleHeartDisease and Bilateral Superior Caval Veins.

Schwartz MC, Nykanen D, DeCampli W, Pourmoghadam K.

World J Pediatr Congenit Heart Surg. 2017 Mar;8(2):215-219. doi: 10.1177/2150135116679824. Epub 2016 Dec 7.

PMID:

 

27927943

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Select item 27154795 337.

 

  1. Survival of Three Neonates WithCongenitalDiaphragmatic Hernia and d-Transposition of the Great Arteries.

Blancha VL, Ratner V, Aspelund G, Chai P, Levasseur S, Krishnan U, Bacha E, Krishnamurthy G.

World J Pediatr Congenit Heart Surg. 2017 Mar;8(2):239-241. doi: 10.1177/2150135116632509. Epub 2016 Jul 7.

PMID:

 

27154795

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Select item 27098606 338

 

  1. Endoventriculoplasty of the Left Ventricle forCongenitalDiverticulum.

Soynov IA, Sinelnikov YS, Nichay NR, Omelchenko AY, Kornilov IA.

World J Pediatr Congenit Heart Surg. 2017 Mar;8(2):227-230. doi: 10.1177/2150135115625204. Epub 2016 Jul 8.

PMID:

 

27098606

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  1. Acute kidney injury and fluid overload in infants and children after cardiac surgery.

Kwiatkowski DM, Krawczeski CD.

Pediatr Nephrol. 2017 Mar 30. doi: 10.1007/s00467-017-3643-2. [Epub ahead of print]

PMID:

 

28361230

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Select item 28370952 80.

 

  1. An Alternative Strategy for Bridge-to-Transplant/Recovery in Small Children with Dilated Cardiomyopathy.

Mets G, Panzer J, De Wolf D, Bové T.

Pediatr Cardiol. 2017 Mar 29. doi: 10.1007/s00246-017-1610-0. [Epub ahead of print] Review.

PMID:

 

28357450

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Select item 28349207 84.

 

  1. Reducing PediatricSternal Wound Infections: A Quality Improvement Project.

Delgado-Corcoran C, Van Dorn CS, Pribble C, Thorell EA, Pavia AT, Ward C, Smout R, Bratton SL, Burch PT.

Pediatr Crit Care Med. 2017 Mar 27. doi: 10.1097/PCC.0000000000001135. [Epub ahead of print]

PMID:

 

28350561

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Select item 28347534 88.

 

  1. Interstage Weight Gain Is Associated With Survival After First-Stage Single-Ventricle Palliation.

Evans CF, Sorkin JD, Abraham DS, Wehman B, Kaushal S, Rosenthal GL.

Ann Thorac Surg. 2017 Mar 24. pii: S0003-4975(16)31889-6. doi: 10.1016/j.athoracsur.2016.12.031. [Epub ahead of print]

PMID:

 

28347534

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Select item 28341781 89.

 

  1. Hypoplastic Left Heart Syndrome is not Associated with Worse Clinical or Neurodevelopmental Outcomes Than Other Cardiac Pathologies After the Norwood-Sano Operation.

Martin BJ, De Villiers Jonker I, Joffe AR, Bond GY, Acton BV, Ross DB, Robertson CM, Rebeyka IM, Atallah J.

Pediatr Cardiol. 2017 Mar 24. doi: 10.1007/s00246-017-1598-5. [Epub ahead of print]

PMID:

 

28341901

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Select item 28337515 97.

 

  1. The Effects of Center Volume on Mortality in PediatricHeart Transplantation- The Rest of the Story.

Canter CE.

Am J Transplant. 2017 Mar 23. doi: 10.1111/ajt.14277. [Epub ahead of print]

PMID:

 

28332766

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Select item 28332701 99.

 

  1. Concomitant pulsatile and continuous flow VAD in biventricular and univentricular physiology: a comparison study with a numerical model.

Di Molfetta A, Ferrari G, Iacobelli R, Filippelli S, Guccione P, Fresiello L, Perri G, Amodeo A.

Int J Artif Organs. 2017 Mar 16;40(2):74-81. doi: 10.5301/ijao.5000562. Epub 2017 Feb 11.

PMID:

 

28218352

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Select item 28299589 133.

 

  1. Gothic aortic arch and cardiac mechanics in young patients after arterial switch operation for d-transposition of the great arteries.

Di Salvo G, Bulbul Z, Pergola V, Issa Z, Siblini G, Muhanna N, Galzerano D, Fadel B, Al Joufan M, Al Fayyadh M, Al Halees Z.

Int J Cardiol. 2017 Mar 11. pii: S0167-5273(17)30958-0. doi: 10.1016/j.ijcard.2017.03.044. [Epub ahead of print]

PMID:

 

28325614

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Select item 28285322 164.

 

  1. Implications and outcomes of cardiac grafts refused by pediatriccenters but transplanted by adult centers.

Zafar F, Rizwan R, Lorts A, Bryant R 3rd, Tweddell JS, Chin C, Morales DL.

J Thorac Cardiovasc Surg. 2017 Mar 11. pii: S0022-5223(17)30413-0. doi: 10.1016/j.jtcvs.2016.12.071. [Epub ahead of print]

PMID:

 

28366553

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Select item 28294539 166.

 

  1. Feasibility and interpretation of global longitudinal strain imaging in pediatricheart transplant recipients.

Wisotzkey BL, Jorgensen NW, Albers EL, Kemna MS, Boucek RJ, Kronmal RA, Law YM, Bhat AH.

Pediatr Transplant. 2017 Mar 10. doi: 10.1111/petr.12909. [Epub ahead of print]

PMID:

 

28295946

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Select item 28295792 170.

 

  1. Biventricular impact of mild to moderate pulmonary valve stenosis in fetal life.

Guirado L, Crispi F, Masoller N, Bennasar M, Marimon E, Carretero J, Gratacós E, Martínez JM, Friedberg MK, Gómez O.

Ultrasound Obstet Gynecol. 2017 Mar 10. doi: 10.1002/uog.17456. [Epub ahead of print]

PMID:

 

28295792

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Select item 28281093 171.

 

  1. Impact of Heart Transplantation on the Functional Status of US Children With End-Stage Heart Failure.

Peng DM, Zhang Y, Rosenthal DN, Palmon M, Chen S, Kaufman BD, Maeda K, Hollander SA, McDonald N, Smoot LB, Bernstein D, Almond CS.

Circulation. 2017 Mar 7;135(10):939-950. doi: 10.1161/CIRCULATIONAHA.115.016520. Epub 2017 Jan 24.

PMID:

 

28119383

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Select item 28329313 180.

 

  1. Importance of multidisciplinary management for pulmonary atresia, ventricular septal defect, major aorto-pulmonary collateral arteries and completely absent central pulmonary arteries.

Hoashi T, Yazaki S, Kagisaki K, Kitano M, Shimada M, Shiraishi I, Ichikawa H.

Gen Thorac Cardiovasc Surg. 2017 Mar 4. doi: 10.1007/s11748-017-0765-1. [Epub ahead of print]

PMID:

 

28260150

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Select item 28258593 197.

 

  1. Dynamic Changes in Aortic Vascular Stiffness in Patients Bridged to Transplant With Continuous-Flow Left Ventricular Assist Devices.

Patel AC, Dodson RB, Cornwell WK 3rd, Hunter KS, Cleveland JC Jr, Brieke A, Lindenfeld J, Ambardekar AV.

JACC Heart Fail. 2017 Mar 4. pii: S2213-1779(17)30046-X. doi: 10.1016/j.jchf.2016.12.009. [Epub ahead of print]

PMID:

 

28285118

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Select item 28258178 199.

 

  1. Femoral Vein Homograft as Right Ventricle to Pulmonary Artery Conduit in Stage 1 Norwood Operation.

Kumar TK, Briceno-Medina M, Sathanandam S, Joshi VM, Knott-Craig CJ.

Ann Thorac Surg. 2017 Mar 2. pii: S0003-4975(16)31819-7. doi: 10.1016/j.athoracsur.2016.11.078. [Epub ahead of print]

PMID:

 

28262297

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Select item 28363739 204.

 

  1. Functional status of United States children supported with a left ventricular assist device at heart transplantation.

Bulic A, Maeda K, Zhang Y, Chen S, McElhinney DB, Dykes JC, Hollander AM, Hollander SA, Murray J, Reinhartz O, Gowan MA, Rosenthal DN, Almond CS.

J Heart Lung Transplant. 2017 Mar 2. pii: S1053-2498(17)31675-3. doi: 10.1016/j.healun.2017.02.024. [Epub ahead of print]

PMID:

 

28363739

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Select item 28251726 205.

 

  1. Genomic Contraindications for Heart Transplantation.

Char DS, Lázaro-Muñoz G, Barnes A, Magnus D, Deem MJ, Lantos JD.

Pediatrics. 2017 Mar 2. pii: e20163471. doi: 10.1542/peds.2016-3471. [Epub ahead of print]

PMID:

 

28255068

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Select item 28255743 207.

 

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Rana A, Fraser CD, Scully BB, Heinle JS, McKenzie ED, Dreyer WJ, Kueht M, Liu H, Brewer ED, Rosengart TK, O’Mahony CA, Goss JA.

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Mery CM, Nieto RM, De León LE, Morris SA, Zhang W, Colquitt JL, Adachi I, Kane LC, Heinle JS, McKenzie ED, Fraser CD Jr.

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  1. Neonatal Ebstein repair-where are we now?

Wackel PL, Dearani JA, Cetta F.

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Di Molfetta A, Ferrari G, Iacobelli R, Filippelli S, Fresiello L, Guccione P, Toscano A, Amodeo A.

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Patel ND, Badran S, Kung G.

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Cardiol Young. 2017 Mar;27(2):325-332. doi: 10.1017/S1047951116000573. Epub 2016 May 19.

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François K, Panzer J, De Groote K, Vandekerckhove K, De Wolf D, De Wilde H, Marchau F, De Caluwe W, Benatar A, Bové T.

Eur J Pediatr. 2017 Mar;176(3):371-377. doi: 10.1007/s00431-017-2850-y. Epub 2017 Jan 13.

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Rettiganti M, Seib PM, Robertson MJ, Wilcox A, Gupta P.

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Perri G, Filippelli S, Adorisio R, Iacobelli R, Iodice F, Testa G, Paglietti MG, D’Amario D, Massetti M, Amodeo A.

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Koth AM, Axelrod DM, Reddy S, Roth SJ, Tacy TA, Punn R.

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Aggarwal S, Blake J, Sehgal S.

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Hollander SA.

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Lewis K, Butts R, Antonio Quiros J, Hudspeth M, Twombley K, Savage A, Self S, Burnette A, Sun S.

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Goel AN, Iyengar A, Schowengerdt K, Fiore AC, Huddleston CB.

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27933693

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  1. Current Practices in the Timing of Stage 2 Palliation.

Meza JM, Jaquiss RD, Anderson BR, Moga MA, Kirklin JK, Sarris G, Williams WG, McCrindle BW; Congenital Heart Surgeons’ Society..

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CHD Intervention Featured Articles of March 2017

 

Interventional Cardiology Featured Reviews of February-March 2017 Publications 

 

Surgical rescue after transcatheter interventional procedures in congenital heart disease patients: an existing problem.

Varrica A, Lo Rito M, Generali T, Satriano A, D’Oria V, Conforti E, Pluchinotta F, Chessa M, Butera G, Frigiola A, Carminati M, Giamberti A.

EuroIntervention. 2017 Feb 20;12(14):1724-1729. doi: 10.4244/EIJ-D-16-00031.

PMID:27773863

Free Article

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Take Home Points:

 

  • Despite improvements in catheterization equipment and techniques, there is still the potential need for surgical intervention after cath-based intervention in immediate and short-term follow-up.
  • This study stresses the importance of the availability of surgical colleagues, particularly during challenging cath-based interventions, as well as long term follow-up to look for future complications.

 Seckler, MikeCommentary from Dr. Michael Seckeler (Tucson), section editor of Congenital Heart Interventions Journal Watch:  Varrica and colleagues present a retrospective review of their single-center experience with interventional cardiac catheterizations and assess the rate of surgical interventions following catheterization. They divided the cases into early complications – during the catheterization or prior to hospital discharge, and late complications – surgery after hospital discharge. Of nearly 7,000intervention media v1

catheterizations during the review period, 3,205 involved an intervention (Table 1). A total of 40 patients (1.2%) required surgical intervention and 55% of interventions were early.

 

Atrial septal defect (ASD) closure required the highest number of surgical interventions, but was also the most commonly performed cath-based intervention. Of the early ASD surgical interventions, 79% were related to device embolization or erosion. The highest need for surgical intervention occurred in the percutaneous pulmonary valve implantation patients – early interventions were for coronary artery compression and device embolization and later interventions were for infective endocarditis involving the implanted valve. Of all late interventions, ASD device complications were the most common cause leading to 72% of surgeries.

Despite the limitation of being a single-center study, the large number of patients and long follow-up period provide additional insight into the risks of cath-based interventions in the current era as well as the importance of continued follow-up after interventions are performed.

Cardiac 3D Printing and its Future Directions.

Vukicevic M, Mosadegh B, Min JK, Little SH.

JACC Cardiovasc Imaging. 2017 Feb;10(2):171-184. doi: 10.1016/j.jcmg.2016.12.001. Review.

PMID: 28183437

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Take Home Points:

 

  • 3-D printing is being increasingly utilized in congenital and structural cardiac interventions.
  • Methods are expanding beyond simple anatomic visualization and now include the potential to physically model and assess hemodynamics in vitro to more accurately guide appropriate interventions and development of new interventional devices.

 

Commentary from Dr. Michael Seckeler (Tucson), section editor of Congenital Heart Interventions Journal Watch:  The authors provide an overview of the available 3-D printing technologies and their different capabilities regarding model resolution and material availability. They also outline the steps of generating a 3-D model from initial image acquisition of a 3-D volumetric dataset (typically CT or MR data),

 

intervention media v2

through image segmentation (the process of highlighting the pertinent anatomical structures), 3-D reconstruction, generating a digital 3-D model and finally printing the physical model.

 

The multiple uses of 3-D printed models that have been developed so far are also presented. These include:

  1. Trainee and patient education, particularly of complex congenital heart defects
  2. Functional flow models which have been used to model aortic stenosis and coronary artery flow
  3. Surgical and catheterization procedural planning, including double outlet right ventricle repair, complex percutaneous pulmonary valve implantation and aortic coarctation stenting
  4. Development of new devices that are more appropriate for human anatomy rather than using animal models

 

They conclude with a discussion of currently available printing materials and their different mechanical properties followed by a review of critical developments in the literature for different aspects of creating 3-D printed models. Importantly, limitations of the currently available technology are presented, including accuracy of mechanical properties of the materials to simulate cardiac muscle and a lack of validation of model accuracy across a variety of generation methods and 3-D printing hardware.

 

Long-term outcomes and re-interventions following balloon aortic valvuloplasty in pediatric patients with congenital aortic stenosis: A single-center study.

Sullivan PM, Rubio AE, Johnston TA, Jones TK.

Catheter Cardiovasc Interv. 2017 Feb 1;89(2):288-296. doi: 10.1002/ccd.26722.

PMID: 27650723

 

Take Home Points:

 

  • BAV is a safe and effective option for patients with AS requiring intervention in the short term.
  • There is a low long-term mortality and need for cardiac transplantation.
  • Moderate-severe AI post-BAV may place patients at higher risk of requiring AVR in the long-term compared to post-BAV AS and may argue for a more conservative strategy in the cath lab.

Commentary from Dr. Konstantin Averin (Edmonton), section editor of Congenital Heart Interventions Journal Watch:  At many centers, balloon aortic valvuloplasty (BAV) has become the procedure of choice for pediatric patients with aortic stenosis requiring intervention. In this paper, the authors report a single center experience with BAV in neonates, infants and children with up to 20 years of follow up. The aims of the study were to: (1) describe the long-term risk of mortality or heart transplantation, significant AI and LVOT re-intervention (i.e. aortic valve replacement); and (2) to identify risk factors for re-interventions on the LVOT.

 

One hundred and fifty-four patients who underwent BAV between 1993 and 2013 were included for analysis with a median follow up of 6.1 years. There were no procedural deaths, 9 total deaths, and 2 patients who underwent heart transplantation at a median of 51 days after the procedure.  At 15 years, post-procedure transplant free survival was 85% in those who underwent BAV as neonates, 94% in those who underwent BAV between 31 days and 1 year and 100% in those who were older than 1 year at time of BAV. 35% of patients underwent at least 1 LVOT intervention, with repeat BAV – 46% and Ross-Konno – 22% being the most common. Only 45% of neonates and 62% of infants and older children were estimated to remain free from AVR 15 years after BAV. On multivariate analysis, neonatal age, additional obstructive left heart lesions (HR 2.7), pre-cath gradient > 80mmHg (HR 2.8), post-gradient > 30mmHg (HR 4.5) and moderate-severe acute AI (2.6) were associated with an elevated risk for LVOT re-intervention. Interestingly, on multi-variate analysis adjusted by year of catheterization the risk of post-BAV AVR was much higher in those with moderate-severe AI (HR 10.4) compared to those with post-BAV AS (HR 3.0).

 

The authors conclude that BAV carries a low long-term risk of mortality but that there is a substantial long-term risk of valve dysfunction and re-intervention (including AVR). The most clinically relevant finding from this paper may be that acute AI is associated with a significantly greater risk of AVR compared to residual AS suggesting that a more conservative approach may be prudent.

 

Cardiac 3D Printing and its Future Directions.

Vukicevic M, Mosadegh B, Min JK, Little SH.

JACC Cardiovasc Imaging. 2017 Feb;10(2):171-184. doi: 10.1016/j.jcmg.2016.12.001. Review.

PMID: 28183437

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Clinical evaluation of a radio-protective cream for the hands of the pediatric interventional cardiologist.

Subramanian S, Waller BR, Winders N, Bird LE, Agrawal V, Zurakowski D, Kuhls-Gilcrist A, Khandkar A, Sathanandam SK.

Catheter Cardiovasc Interv. 2017 Mar 1;89(4):709-716. doi: 10.1002/ccd.26845. Epub 2016 Nov 26.

PMID: 27888578

 

Take Home Points:

 

  • Pediatric interventional cardiologists are exposed to increasing amounts of radiation as the complexity and number of pediatric procedures increases.
  • Operators hands are unprotected during procedures.
  • The UltraBloxTM cream provides a new option for radio-protection for the hands of the pediatric interventional cardiologist, offering 40% radiation attenuation.

Commentary from Dr. Konstantin Averin (Edmonton), section editor of Congenital Heart Interventions Journal Watch:  As the complexity of pediatric catheterization procedures increases, providers are exposed to increasing amount ionizing radiation. Operators hands are directly under the primary entrance or exit radiation beams and are typically unprotected. The authors conducted a single center, prospective, controlled clinal study utilizing UltraBloxTM cream, a new FDA approved radiation-attenuation cream. The aims of the study were to: (1) determine the percent reduction of radiation exposure using the cream up to 180 minutes; and (2) determine user comfort and satisfaction with the cream.

 

40 patients were recruited for the study and the procedures were classified into 4 categories (10 each) by procedure duration: 0-30, 31-60, 61-120, and 121-180 minutes. The 4 groups were well matched by patient age, weight and body surface area. The overall percentage attenuation by the cream on the operator’s hand was 39.7% and was not affected by procedure duration or increased radiation doses. The overall median percentage satisfaction was 92% among all operators with ease of application and tactile sensation generally well rated.

 

The authors conclude that the UltraBloxTM cream provides a new option for radio-protection for the hands of the pediatric interventional cardiologist, offering 40% radiation attenuation. The protection decreases neither for prolonged procedures (up to 180 minutes) nor with increasing radiation doses. Operators rated the cream as relatively easy to use with little loss of tactile sensation.

 

 

Infective Endocarditis Risk After Percutaneous Pulmonary Valve Implantation with the Melody and Sapien Valves.

Hascoet S, Mauri L, Claude C, Fournier E, Lourtet J, Riou JY, Brenot P, Petit J.

JACC Cardiovasc Interv. 2017 Mar 13;10(5):510-517. doi: 10.1016/j.jcin.2016.12.012.

 

Take Home Points:

 

  • The incidence of infective endocarditis following percutaneous pulmonary valve implantation has been of increasing concern.
  • This single center study utilizing both Melody and Sapien valves found a higher incidence of infective endocarditis in patients with Melody PPVI (5.7% per person-year) compared with Sapien PPVI (No cases during follow-up).

 

Whiteside, WendyCommentary from Dr. Wendy Whiteside (Cincinnati), section editor of Congenital Heart Disease Interventions Journal Watch: Infective endocarditis (IE) has emerged as one of the most concerning adverse outcomes following percutaneous pulmonary valve implantation (PPVI).  The annual incidence of IE after PPVI with the Melody valve is reported around 3%, however adequate quantities and duration of follow-up has not yet been available for the newer Sapien valve to allow for a balanced comparison of these valve types.

 

Hascoet et al present findings from a single center retrospective cohort study evaluating IE after PPVI between the two now commercially available transcatheter pulmonary valves—Medtronic Melody and Edwards Sapien. They looked at 79 patients who received PPVI between 2008-2016.  Melody valve was used in 40.5% and Sapien in 59.5% of patients.  With its larger diameter valves available, it is not surprising that patients who received the Sapien valve were older, larger, and had a higher proportion of native right ventricular outflow tract valve implantations (not within a previously placed surgical conduit/bioprosthesis).  IE, diagnosed based on the European Society of Cardiology modified Duke algorithm, occurred in 8 patients (10.1%) a median of 1.8 years (range 12.2 months-5.6 years) after PPVI, for an incidence of 3.9% per person-year.  Median follow-up was longer in the Melody group (4.9 years, IQR 2.2-6.5) compared with the Sapien group (1.0 years, IQR 0.2-2.6). All 8 patients with IE had received Melody PPVI (IE incidence 5.7% per person-year in the Melody group compared with 0% in the Sapien group).  Valve gradient was increased at IE diagnosis in 7 of the 8 patients—4 required elective surgical valve explantation and 2 required delayed surgical valve explantation. There was one death due to septic shock the day after fever onset.

 

While this single center study allows for comparison of PPVI within a center with similar implantation technique and follow-up practices, there are important limitations, which are recurrent among studies evaluating IE among different valve types.  These include differences in follow-up duration, change in technique over time, and anatomic substrate (small stenotic conduit vs large regurgitant native outflow) for PPVI. In fact, in this case, the majority (7 IE cases) occurred among the first 19 patients performed at this center with the remaining 1 IE case occurring among the remaining cases.  Between these two-time periods, there was a change in administration practices of antibiotics from a single intraprocedural antibiotic dose to a 48-hour course, followed within a few years by a shift in the valve type used from exclusively Melody to majority Sapien.

 

While this study suggests a higher IE risk with the Melody valve that is certainly worth noting, it again points out the need for larger, multi-center studies, with longer follow-up duration to truly understand the difference between these valve types.  Being a newer valve in the pulmonary position, we do not have the same long term-follow-up and experience with the durability of the Sapien valve as with the Melody valve so caution should be taken in shifting practice now based upon these data.

 

 

 

The Medtronic Micro Vascular Plug™ for Vascular Embolization in Children with Congenital Heart Diseases.

Sathanandam S, Justino H, Waller BR 3rd, Gowda ST, Radtke W, Qureshi AM.

J Interv Cardiol. 2017 Feb 16. doi: 10.1111/joic.12369. [Epub ahead of print]

PMID: 28211168

 

Take home points:

 

  • Occlusion of abnormal blood vessels (including aorto-pulmonary and veno-venous collaterals) in patients with congenital heart disease can be challenging due to small patient size and potentially tortuous vascular anatomy.
  • The Medtronic Micro-vascular plug allows for deployment of a large diameter, detachable device for vascular occlusion/embolization through a microcatheter.

 

Commentary from Dr. Wendy Whiteside (Cincinnati), section editor of Congenital Heart Disease Interventions Journal Watch: In pediatric interventional cardiology, we are often challenged with finding devices which have a sufficiently flexible and small delivery system to be used to close medium to large structures in small patients with complex anatomy.  Sathanandam et al describe their multi-center experience with implantation of a Medtronic Micro Vascular Plug (MVP) in patients with congenital heart disease.  The MVP is the first detachable plug deliverable through a microcatheter (6.5 mm device can be introduced through 0.027” inner diameter catheter) and has been used for vascular embolization primarily in neuroradiology procedures in adults.  The device has a highly flexible 0.018” delivery wire and device has a flexible nitinol frame covered partially by a polytetrafluoroethylene membrane.

 

In this 3-center, retrospective observational study, Sathanandam et al describe the use of the MVP for occlusion of abnormal blood vessels in 8 pediatric patients (median age 3 years, median weight 14.9 kg).  Vessels occluded included veno-venous collaterals in single ventricle patients (5), aorto-pulmonary collateral vessels (2), and coronary artery fistula (3).  The most common indication for using the MVP was failed attempted occlusion using other embolic devices (5/8 patients, 62.5%) due to catheter kinking and acute vessel/catheter turns. There was complete vessel closure in all collateral vessels with no procedural or long term complications (median 7 months, range 4-12 months).  2/3 coronary artery fistula were successfully closed with one patient having distal device embolization with residual shunt.  While this study describes a limited experience in pediatric patients, its application in pediatric congenital heart patients may allow for a safer, more controlled, and more effective vessel occlusion in tortuous vessels that are too large for micro-coil placement.

 

CHD Interventions March 2017

 

  1. Infective Endocarditis Risk After Percutaneous Pulmonary Valve Implantation With the Melody and Sapien Valves.

Hascoet S, Mauri L, Claude C, Fournier E, Lourtet J, Riou JY, Brenot P, Petit J.

JACC Cardiovasc Interv. 2017 Mar 13;10(5):510-517. doi: 10.1016/j.jcin.2016.12.012.

PMID:

 

28279319

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Ishigami S, Ohtsuki S, Eitoku T, Ousaka D, Kondo M, Kurita Y, Hirai K, Fukushima Y, Baba K, Goto T, Horio N, Kobayashi J, Kuroko Y, Kotani Y, Arai S, Iwasaki T, Sato S, Kasahara S, Sano S, Oh H.

Circ Res. 2017 Mar 31;120(7):1162-1173. doi: 10.1161/CIRCRESAHA.116.310253. Epub 2017 Jan 4.

PMID:

 

28052915

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  1. Clinical Progress in Cell Therapy for Single VentricleCongenital Heart Disease.

Bittle GJ, Wehman B, Karathanasis SK, Kaushal S.

Circ Res. 2017 Mar 31;120(7):1060-1062. doi: 10.1161/CIRCRESAHA.117.310702. No abstract available.

PMID:

 

28360342

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  1. Patient-specific in vitro models for hemodynamic analysis ofcongenital heart disease– Additive manufacturing approach.

Medero R, García-Rodríguez S, François CJ, Roldán-Alzate A.

J Biomech. 2017 Mar 21;54:111-116. doi: 10.1016/j.jbiomech.2017.01.048. Epub 2017 Feb 7.

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28242061

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Kenny DP, Hijazi ZM.

Circ Res. 2017 Mar 17;120(6):1015-1026. doi: 10.1161/CIRCRESAHA.116.309185.

PMID:

 

28302745

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  1. Impact of Three-Dimensional Printing on the Study and Treatment ofCongenital Heart Disease.

Bramlet M, Olivieri L, Farooqi K, Ripley B, Coakley M.

Circ Res. 2017 Mar 17;120(6):904-907. doi: 10.1161/CIRCRESAHA.116.310546. No abstract available.

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28302738

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  1. Severe Aortic Stenosis and Severe Coarctation of the Aorta: A Hybrid Approach to Treatment.

McLennan D, Caputo M, Taliotis D.

Front Surg. 2017 Mar 17;4:16. doi: 10.3389/fsurg.2017.00016. eCollection 2017.

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Mohammad Nijres B, Kenny D, Kazmouz S, Hijazi ZM.

Catheter Cardiovasc Interv. 2017 Mar 15. doi: 10.1002/ccd.26996. [Epub ahead of print]

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Pagourelias ED, Daraban AM, Mada RO, Duchenne J, Mirea O, Cools B, Heying R, Boshoff D, Bogaert J, Budts W, Gewillig M, Voigt JU.

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Dimas VV, Morray BH, Kim DW, Almond CS, Shahanavaz S, Tume SC, Peng LF, McElhinney DB, Justino H.

Catheter Cardiovasc Interv. 2017 Mar 15. doi: 10.1002/ccd.26973. [Epub ahead of print]

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Rajan D, Lakshmanan G, Gupta SK, Sivasubramanian R, Saxena A, Juneja R.

Indian Pediatr. 2017 Mar 15;54(3):204-207. Epub 2017 Feb 2.

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Słodki M, Axt-Fliedner R, Zych-Krekora K, Wolter A, Kawecki A, Enzensberge C, Gulczyńska E, Respondek-Liberska M; International Prenatal Cardiology Collaboration Group..

Ultrasound Obstet Gynecol. 2017 Mar 14. doi: 10.1002/uog.17469. [Epub ahead of print]

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Meot M, Lefort B, El Arid JM, Soulé N, Lothion-Boulanger J, Lengellé F, Chantepie A, Neville P.

Ann Thorac Surg. 2017 Mar 5. pii: S0003-4975(16)31825-2. doi: 10.1016/j.athoracsur.2016.12.012. [Epub ahead of print]

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Arch Med Sci. 2017 Mar 1;13(2):337-345. doi: 10.5114/aoms.2016.61836. Epub 2016 Nov 28.

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Fiszer R, Dryżek P, Szkutnik M, Góreczny S, Krawczuk A, Moll J, Moszura T, Pawlak S, Białkowski J.

Cardiol J. 2017 Mar 1. doi: 10.5603/CJ.a2017.0023. [Epub ahead of print]

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Levert EM, Helbing WA, Dulfer K, van Domburg RT, Utens EM.

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Rigatelli G, Zuin M, Pedon L, Zecchel R, Dell’Avvocata F, Carrozza A, Zennaro M, Pastore G, Zanon F.

Cardiovasc Revasc Med. 2017 Mar;18(2):118-122. doi: 10.1016/j.carrev.2016.10.008. Epub 2016 Oct 29.

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Shebani SO, Rehman R, Taliotis D, Magee A, Hayes NJ, Baspinar O, Martínez Z, Haas N, Duke C.

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Schubert S, Peters B, Berger F.

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Ou-Yang WB, Wang SZ, Hu SS, Zhang FW, Zhang DW, Liu Y, Meng H, Pang KJ, Meng LK, Pan XB.

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Okada S, Kamada M, Nakagawa N, Ishiguchi Y, Moritoh Y, Shohi M, Okamoto K, Hasegawa S, Ohga S.

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  1. Distribution of Kawasaki Disease Coronary Artery Aneurysms and the Relationship to Coronary Artery Diameter.

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Pediatr Cardiol. 2017 Mar 20. doi: 10.1007/s00246-017-1599-4. [Epub ahead of print]

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  1. Giant aneurysms: A gender-specific complication of Kawasaki disease?

Dietz SM, Kuipers IM, Tacke CE, Koole JC, Hutten BA, Kuijpers TW.

J Cardiol. 2017 Mar 18. pii: S0914-5087(17)30017-5. doi: 10.1016/j.jjcc.2016.12.014. [Epub ahead of print]

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  1. Anchor balloon, buddy wire, and wire and sheath techniques to deploy percutaneous pulmonary valves in tetralogy of fallot patients.

Shah RR, Poommipanit P, Law MA, Amin Z.

Catheter Cardiovasc Interv. 2017 Mar 17. doi: 10.1002/ccd.27022. [Epub ahead of print]

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  1. Into the hearts of babes: Stem cell therapy for pediatricheart failure.

Garbern JC, Daly KP.

J Heart Lung Transplant. 2017 Mar 9. pii: S1053-2498(17)31683-2. doi: 10.1016/j.healun.2017.03.006. [Epub ahead of print] No abstract available.

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28365176

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  1. Hemolytic Anemia due to Right Ventricular to Pulmonary Artery Conduit Stenosis.

Rao S, Creaden JA, Gong S, Rigsby C, Costello JM.

J Pediatr Hematol Oncol. 2017 Mar 6. doi: 10.1097/MPH.0000000000000801. [Epub ahead of print]

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Gruenstein DH, Ebeid M, Radtke W, Moore P, Holzer R, Justino H.

Catheter Cardiovasc Interv. 2017 Mar 4. doi: 10.1002/ccd.26968. [Epub ahead of print]

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  1. Clinical evaluation of a radio-protective cream for the hands of the pediatricinterventional cardiologist.

Subramanian S, Waller BR, Winders N, Bird LE, Agrawal V, Zurakowski D, Kuhls-Gilcrist A, Khandkar A, Sathanandam SK.

Catheter Cardiovasc Interv. 2017 Mar 1;89(4):709-716. doi: 10.1002/ccd.26845. Epub 2016 Nov 26.

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Celebi A, Yucel IK, Bulut MO, Kucuk M, Balli S.

Catheter Cardiovasc Interv. 2017 Mar 1;89(4):699-708. doi: 10.1002/ccd.26796. Epub 2016 Nov 10.

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  1. Closure of very large PDA with pulmonary hypertension: Initial clinical case-series with the new Occlutech®PDA occluder.

Lehner A, Ulrich S, Happel CM, Fischer M, Kantzis M, Schulze-Neick I, Haas NA.

Catheter Cardiovasc Interv. 2017 Mar 1;89(4):718-725. doi: 10.1002/ccd.26856. Epub 2016 Nov 10.

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  1. Sheath placement in femoral artery during cardiac catheterization in children can influence pressure waveform.

Shiraishi M, Murakami T, Nawa T, Higashi K, Nakajima H, Aotsuka H.

Int J Cardiol. 2017 Mar 1;230:21-24. doi: 10.1016/j.ijcard.2016.12.118. Epub 2016 Dec 22.

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Chun Y, Kealey CP, Levi DS, Rigberg DA, Chen Y, Tillman BW, Mohanchandra KP, Shayan M, Carman GP.

J Biomater Appl. 2017 Mar;31(8):1196-1202. doi: 10.1177/0885328216682691. Epub 2016 Dec 8.

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El-Sisi A, Sobhy R, Jaccoub V, Hamza H.

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Pediatr Cardiol. 2017 Mar;38(3):624-630. doi: 10.1007/s00246-016-1559-4. Epub 2017 Feb 18.

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  1. Initial Experience with Elective Perventricular Melody Valve Placement in Small Patients.

Gupta A, Kenny D, Caputo M, Amin Z.

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  1. Transcatheter Pulmonary Valve Replacement and Acute Increase in Diastolic Pressure are Associated with Increases in Both Systolic and Diastolic Pulmonary Artery Dimensions.

Callahan R, Bergersen L, Lock JE, Marshall AC.

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  1. Echocardiographic right ventricular function correlations with cardiac catheterisation data in biventricular congenital heart patients.

Nadorlik H, Stiver C, Khan S, Miao Y, Holzer R, Cheatham JP, Cua CL.

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  1. Usefulness of intracardiac echocardiography for the diagnosis of infective endocarditis following percutaneous pulmonary valve replacement.

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  1. Stent implantation to ductus arteriosus in a patient with interrupted aortic arch guided by CT image overlay.

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Eicken A, Georgiev S, Ewert P.

Cardiol Young. 2017 Mar 6:1-4. doi: 10.1017/S1047951117000142. [Epub ahead of print]

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28260540

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  1. Infective endocarditis following Melody valve implantation: comparison with a surgical cohort.

O’Donnell C, Holloway R, Tilton E, Stirling J, Finucane K, Wilson N.

Cardiol Young. 2017 Mar;27(2):294-301. doi: 10.1017/S1047951116000494. Epub 2016 May 10.

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Fetal Cardiology Featured Articles of February 2017

Fetal Cardiology Feb 2017

Teratogenicity of Antiepileptic Drugs.

Güveli BT, Rosti RÖ, Güzeltaş A, Tuna EB, Ataklı D, Sencer S, Yekeler E, Kayserili H, Dirican A, Bebek N, Baykan B, Gökyiğit A, Gürses C.

Clin Psychopharmacol Neurosci. 2017 Feb 28;15(1):19-27. doi: 10.9758/cpn.2017.15.1.19.

PMID: 28138106 Free PMC Article

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Karakikes I, Termglinchan V, Cepeda DA, Lee J, Diecke S, Hendel A, Itzhaki I, Ameen M, Shrestha R, Wu H, Ma N, Shao NY, Seeger T, Woo NA, Wilson KD, Matsa E, Porteus MH, Sebastiano V, Wu JC.

Circ Res. 2017 Feb 28. pii: CIRCRESAHA.116.309948. doi: 10.1161/CIRCRESAHA.116.309948. [Epub ahead of print]

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Zhou L, Liu J, Xiang M, Olson P, Guzzetta A, Zhang K, Moskowitz IP, Xie L.

Proc Natl Acad Sci U S A. 2017 Feb 21;114(8):E1422-E1431. doi: 10.1073/pnas.1605137114.

PMID: 28167794

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Ford SM, McPheeters MT, Wang YT, Ma P, Gu S, Strainic J, Snyder C, Rollins AM, Watanabe M, Jenkins MW.

Congenit Heart Dis. 2017 Feb 17. doi: 10.1111/chd.12443. [Epub ahead of print]

PMID: 28211263

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  1. Increased Hemodynamic Load in Early Embryonic Stages Alters Endocardial to Mesenchymal Transition.

Midgett M, López CS, David L, Maloyan A, Rugonyi S.

Front Physiol. 2017 Feb 8;8:56. doi: 10.3389/fphys.2017.00056.

PMID: 28228731 Free PMC Article

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  1. Total anomalous pulmonary venous connection to an unroofed coronary sinus diagnosed in a fetus with associated spinal muscular atrophy type I.

Krupickova S, Rigby ML, Jicinska H, Marais G, Rubens M, Carvalho JS.

Ultrasound Obstet Gynecol. 2017 Feb 7. doi: 10.1002/uog.17432. [Epub ahead of print]

PMID: 28170121

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  1. Mutation Screening of Gata4 Gene in CTD Patients Within Chinese Han Population.

Liu Y, Li B, Xu Y, Sun K.

Pediatr Cardiol. 2017 Feb 4. doi: 10.1007/s00246-016-1542-0. [Epub ahead of print]

PMID: 28161810

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Yester JW, Kühn B.

Curr Cardiol Rep. 2017 Feb;19(2):13. doi: 10.1007/s11886-017-0826-1. Review.

PMID: 28185170

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Yi Y, Tong T, Liu T, Lin Q, Xiong Y, Xu J.

Echocardiography. 2017 Feb;34(2):311-314. doi: 10.1111/echo.13420.

PMID: 27928837

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Bridge CP, Ioannou C, Noble JA.

Med Image Anal. 2017 Feb;36:147-161. doi: 10.1016/j.media.2016.11.006.

PMID: 27907850 Free Article

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  1. Prenatal diagnoses of an uncommon isolated obstructed supracardiac total anomalous pulmonary venous connection: Case report and review of the literature (CARE compliant).

Muntean I, Mărginean C, Stanca R, Togănel R, Pop M, Gozar L.

Medicine (Baltimore). 2017 Feb;96(5):e6061. doi: 10.1097/MD.0000000000006061. Review.

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Select item 28151908

 

  1. Reference Ranges of Fetal Cardiac Biometric Parameters Using Three-Dimensional Ultrasound with Spatiotemporal Image Correlation M Mode and Their Applicability in Congenital Heart Diseases.

Tedesco GD, de Souza Bezerra M, Barros FS, Martins WP, Nardozza LM, Carrilho MC, Moron AF, Carvalho FH, Rolo LC, Araujo Júnior E.

Pediatr Cardiol. 2017 Feb;38(2):271-279. doi: 10.1007/s00246-016-1509-1.

PMID: 27878625

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Select item 27878332

 

  1. Basic heart examination: feasibility study of first-trimester systematic simplified fetal echocardiography.

Quarello E, Lafouge A, Fries N, Salomon LJ; CFEF..

Ultrasound Obstet Gynecol. 2017 Feb;49(2):224-230. doi: 10.1002/uog.15866.

PMID: 26799640

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Select item 28011359

 

  1. Risk Factors for Coarctation of the Aorta on Prenatal Ultrasound: A Systematic Review and Meta-Analysis.

Familiari A, Morlando M, Khalil A, Sonesson SE, Scala C, Rizzo G, Del Sordo G, Vassallo C, Elena Flacco M, Manzoli L, Lanzone A, Scambia G, Acharya G, D’Antonio F.

Circulation. 2017 Feb 21;135(8):772-785. doi: 10.1161/CIRCULATIONAHA.116.024068.

PMID: 28034902

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Select item 28230785

 

  1. Vegfa Impacts Early Myocardium Development in Zebrafish.

Zhu D, Fang Y, Gao K, Shen J, Zhong TP, Li F.

Int J Mol Sci. 2017 Feb 21;18(2). pii: E444. doi: 10.3390/ijms18020444.

PMID: 28230770 Free Article

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Select item 28220407

 

  1. Increased regurgitant flow causes endocardial cushion defects in an avian embryonic model of congenital heart disease.

Ford SM, McPheeters MT, Wang YT, Ma P, Gu S, Strainic J, Snyder C, Rollins AM, Watanabe M, Jenkins MW.

Congenit Heart Dis. 2017 Feb 17. doi: 10.1111/chd.12443. [Epub ahead of print]

PMID: 28211263

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Select item 28213828

 

  1. Toward Improving the Fetal Diagnosis of Coarctation of the Aorta.

Beattie M, Peyvandi S, Ganesan S, Moon-Grady A.

Pediatr Cardiol. 2017 Feb;38(2):344-352. doi: 10.1007/s00246-016-1520-6.

PMID: 27888318

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Select item 27885446

 

  1. Reference Ranges of Fetal Cardiac Biometric Parameters Using Three-Dimensional Ultrasound with Spatiotemporal Image Correlation M Mode and Their Applicability in Congenital Heart Diseases.

Tedesco GD, de Souza Bezerra M, Barros FS, Martins WP, Nardozza LM, Carrilho MC, Moron AF, Carvalho FH, Rolo LC, Araujo Júnior E.

Pediatr Cardiol. 2017 Feb;38(2):271-279. doi: 10.1007/s00246-016-1509-1.

PMID: 27878625

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Select item 27878332

 

  1. Area of the fetal heart’s four-chamber view: a practical screening tool to improve detection of cardiac abnormalities in a low-risk population.

DeVore GR, Satou G, Sklansky M.

Prenat Diagn. 2017 Feb;37(2):151-155. doi: 10.1002/pd.4980.

PMID: 27943393

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Select item 27891637

 

  1. Fetal magnetocardiography using optically pumped magnetometers: a more adaptable and less expensive alternative?

Eswaran H, Escalona-Vargas D, Bolin EH, Wilson JD, Lowery CL.

Prenat Diagn. 2017 Feb;37(2):193-196. doi: 10.1002/pd.4976.

PMID: 27891637

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Select item 27923603

 

  1. Diverse outcome following early prenatal diagnosis of pulmonary stenosis.

Bronshtein M, Blumenfeld Z, Khoury A, Gover A.

Ultrasound Obstet Gynecol. 2017 Feb;49(2):213-218. doi: 10.1002/uog.17332.

PMID: 27741366

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  1. Congenital pseudoaneurysm of mitral-aortic intervalvular fibrosa masquerading as left atrial mass in fetal life.

Chidambarathanu S, Raja V, Suresh I.

Ann Pediatr Cardiol. 2017 Jan-Apr;10(1):72-74. doi: 10.4103/0974-2069.197062.

PMID: 28163433 Free PMC Article

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ACHD Featured Articles of February 2017

Body mass index in adult congenital heart disease.

Brida M, Dimopoulos K, Kempny A, Liodakis E, Alonso-Gonzalez R, Swan L, Uebing A, Baumgartner H, Gatzoulis MA, Diller GP.

Heart. 2017 Feb 25. pii: heartjnl-2016-310571. doi: 10.1136/heartjnl-2016-310571. [Epub ahead of print]

PMID: 28237971

Similar articles

Select item 28237970

 

Take Home Points:

 

  • ACHD patients with a higher BMI experienced a lower mortality.
  • The association with BMI and mortality is more pronounced in symptomatic patient with complex defects, suggesting that cardiac cachexia may be contributing.
  • Weight loss in complex ACHD patients is linked to higher mortality.

 

Moe_Tabitha-WEBCommentary from Dr. Tabitha Moe (Phoenix), section editor of ACHD Journal Watch:                This is a nice study from groups in the UK and Germany evaluating their cohort of ACHD patients, and they evaluated 3,069 patients with a median age of 32.6 years.  These patients were evaluated between 2000-2015.  In their cohort 6.2% of the patients were classified as underweight, and 14.6% were obese.  By univariable Cox analysis higher BMI values were associated with lower all-cause mortality.  This effect continued despite adjustment for age, complexity of defect, cyanosis, and objective exercise capacity.  This article did not highlight the previously documented associations between congenital heart disease and diabetes or the relationship with an increasing BMI.  There are other additional challenges with high BMI patients including poor wound healing during post-procedural and post-operative states, and difficulty with testing such as table weight limits and magnet diameter limits on cardiac MRI procedure tables. This study lends itself nicely to additional investigations to determine correlations between congenital heart disease and weight related comorbidities as documented in the noncongenital cohort.


 Pregnancy outcomes in patients with pulmonary arterial hypertension associated with congenital heart disease.

Ladouceur M, Benoit L, Radojevic J, Basquin A, Dauphin C, Hascoet S, Moceri P, Bredy C, Iserin L, Gouton M, Nizard J.

Heart. 2017 Feb 15;103(4):287-292. doi: 10.1136/heartjnl-2016-310003.

PMID: 27511447

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Select item 28196030

 

Take Home Points:

  • Maternal cardiovascular morbidity is high in women with Congenital Heart Disease Associated Pulmonary Hypertension. [heart failure and severe cyanosis]
  • Mortality risk in this heterogeneous contemporary cohort of pregnant women with PAH and CHD appears to be low

 

Commentary from Dr. Tabitha Moe (Phoenix), section editor of ACHD Journal Watch: The authors aim to address an important question in this retrospective outcomes study, i.e. of whether improvements in general medical and cardiological care has translated into improved outcomes for women with PAH and congenital heart disease undergoing pregnancy. This relatively small cohort included 28 pregnancies in 20 patients, data being collected by questionnaire from 22 French CHD referral centers between 1997-2015. Study subjects carried the following diagnoses, including: VSD [n=5], Pulmonary Atresia with VSD +/- Aortopulmonary collaterals [n=3], ASD [n=3] and the remaining 9 had any of the following diagnoses: DORV, single ventricle, VSD, Truncus arteriosus, and CCTGA + VSD. Seventeen were considered to have Eisenmenger’s syndrome, 3 having segmental PAH. Only 3 patients were treated with PAH therapies during pregnancy [sildenafil, tadalafil and oxygen therapy]. 85% of the cohort were in NYHA functional class I or II. The most common cardiovascular adverse event were: worsening of hypoxemia, and heart failure requiring inotrope support occurred in 4 pregnancies, one subject required ECMO support.  There was a single maternal mortality in the oldest member of the cohort (42), who died 10 days post-partum. She also had a history of atrial arrhythmia, and moderately impaired RV systolic function.  The diagnosis was not provided. Six patients received antiplatelet or anticoagulant therapy, and there were no cases of hemoptysis. The most common neonatal complications were prematurity in 77.78% percent of births, and almost 40% of fetuses had growth restriction.

The most common obstetric complication was bleeding: 4 with post-partum hemorrhage and 2 with abruptio-placentae. In at least half of these cases of bleeding, the subjects were anticoagulated. There were only 18 completed pregnancies, and 12 (67%) were delivered by caesarean section.

 

Caution should be exercised in the generalization of these results, as the study subjects were a very heterogeneous group in terms of diagnoses and probably also heterogeneous in the degree of pulmonary hypertension. Indeed only 3 had required advanced therapies, suggesting a cohort in a better state of health. Obstetric bleeding was very common and seemed to be associated with formal anticoagulation.

 

Value of Cardiovascular Magnetic Resonance Imaging in Noninvasive Risk Stratification in Tetralogy of Fallot.

Bokma JP, de Wilde KC, Vliegen HW, van Dijk AP, van Melle JP, Meijboom FJ, Zwinderman AH, Groenink M, Mulder BJ, Bouma BJ.

JAMA Cardiol. 2017 Feb 22. doi: 10.1001/jamacardio.2016.5818. [Epub ahead of print]

PMID: 28241248

 

Take Home Points:

 

  • In patients with repaired tetralogy of Fallot, RV EF <30% and LV EF <45% by cardiac MRI can help predict major clinical outcomes, particularly when combined to the non-invasive component of the Khairy et al risk score (prior palliative shunt, ventriculotomy incision, non-sustained ventricular tachycardia, and QRS duration ≥180 ms)

 

jokhadar-maanCommentary from Dr. Maan Jokhadar (Atlanta), section editor of ACHD Journal Watch:   Due to the increased risk of ventricular arrhythmia and sudden death in repaired tetralogy of Fallot (TOF) patients, many require implantable cardiac defibrillators (ICD) for primary or secondary prevention. In 2008, Dr. Khairy and colleagues published a landmark study describing a risk score for appropriate ICD shocks in repaired TOF patients, which included prior palliative shunt, ventriculotomy incision, non-sustained ventricular tachycardia (NSVT), QRS duration ≥180 ms, in addition to 2 invasive parameters that include inducible ventricular tachycardia (VT), and left ventricle and diastolic pressure (LVEDP) ≥ 12 mmHg. (Circulation. 2008; 117:363 – 370)

 

Dr. Bokma and colleagues from the Netherlands performed a multi-center, retrospective cohort study that included 575 patients with repaired TOF who had cardiac MRI. The mean age was 31 and the mean follow-up 7.1 years. This study describes a noninvasive risk model that includes MRI derived LV and RV ejection fraction in place of the invasive parameters used in the Khairy et al risk model.

 

Of 575 patients, 35 (6.1%) had the primary composite endpoint, which included 13 deaths, 8 cardiac arrest/defibrillation, 4 sustained VT, and 11 recurrent and symptomatic NSVT. The 13 deaths included 1 sudden cardiac death, 5 heart failure, 1 renal failure, 1 preoperative bleeding, and 5 non-cardiac or unknown).

 

The C statistic of the noninvasive components of the Khairy et al score was 0.64 (95% CI, 0.54-0.73). The C statistic of the final noninvasive point-based risk model, including RV EF < 30% and LV EF < 45%, was 0.75 (95% CI, 0.63-0.85).

 

Bokma et al risk score:

Prior palliative shunt: 2 points

Ventriculotomy incision: 2 points

QRS duration ≥180 ms: 1 point

Previous VT: 2 points

LV EF <45%: 2 points

RV EF <30%:  3 points
Total points: 0 to 12

High risk: 7 to 12 points

 

These thresholds appear to be applicable in patients with or without pulmonary valve replacement.

 

This noninvasive risk model could be used to help identify patients at risk for ventricular arrhythmia. Though additional studies are needed to determine if this score can help guide ICD implantation, it appears that this noninvasive score can may help identify patients who could benefit from invasive testing such as cardiac catheterization or electrophysiology testing. This study did not include invasive or exercise parameters, echocardiographic parameters (strain, diastolic function, or atrial size), and did not include other MRI parameters (tricuspid regurgitation, ventricular mass, or scar burden). This study does confirm the predictive importance of myocardial dysfunction.

 

 

Limited Ventricular Preload is the Main Reason for Reduced Stress Reserve after Atrial Baffle Repair.

Eicken A, Michel J, Hager A, Tanase D, Kaemmerer H, Cleuziou J, Hess J, Ewert P.

Pediatr Cardiol. 2017 Feb;38(2):353-361. doi: 10.1007/s00246-016-1521-5.

PMID: 27885445

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Select item 27882423

 

Take Home Points:

  • This study showed significant difference in preload reserve between atrial switch patients and normal controls via hemodynamic study in multiple conditions.
  • During catheterization, both groups were studied at baseline, after a volume bolus, with atrial pacing, and with dobutamine
  • Atrial switch patients had a decrease in stroke volume compared to baseline, even at the relatively low rate of 80 beats per minute
  • Patients with severely depressed systemic right ventricular function had severely depressed functional reserve and significantly reduced augmentation of cardiac output with dobutamine
  • Systemic vascular resistance is higher in patients with atrial switch than normal controls

 

Kay_William_MD.16.CVaCommentary from Dr. W. Aaron Kay (Indianapolis), section editor of ACHD Journal Watch:  The atrial switch procedure, although it has been abandoned in favor of the arterial switch procedure, still has a large number of adult survivors throughout the world. Indeed, it was recently demonstrated that the atrial switch procedure is still performed in 30% of cases worldwide for transposition of the great arteries.  Although about 10% of patients have severe RV dysfunction and require transplantation, a large portion of survivors of the Mustard and Senning procedures have minimal symptoms and good quality of life, but in many cases, have limited exercise tolerance.  The exact reasons for this are not well known, and many hypotheses have been presented.

This study from Germany sought to explore the hypothesis that patients after atrial switch have inadequate preload reserve and thus cannot augment systemic blood flow under conditions of higher stress.  The fixed preload is thought to be due to stiff, poorly compliant, atrial baffles, as well as adverse interaction between the pressures in the pulmonary venous atrium versus the systemic venous atrium.

In this study, 49 patients with Mustard or Senning who were having hemodynamic evaluation underwent additional testing under different conditions: baseline (resting), after an intravenous volume bolus, with atrial pacing at 80 bpm, and with dobutamine infusion.  The control group consisted of a much older population who were referred for PFO closer and who consented to have additional hemodynamic measurement under the same conditions after PFO closure.  The control group was significantly older than the atrial switch group (~42 years versus ~23 years).

The authors found that, even though over half of the atrial switch patients were NYHA class I, that there was a significantly lower baseline cardiac index in the atrial switch patients versus controls (2.2 LPM/m2 versus 2.6 LPM/m2).  There was no difference in heart rate response under different conditions between atrial switch group and normal controls.  The cardiac index increased under all conditions, but increased by a smaller amount in the atrial switch group.  Interestingly, the stroke volume decreased from baseline after atrial pacing in the atrial switch group, even though the pacing rate was relatively low at 80 bpm. The exact mechanisms for this observation are unfortunately not further explored in this study.  Of note, Redington et al performed a similar study in 1990, albeit with only 3 pediatric patients who had undergone the Mustard procedure, in which a lack of contractile reserve after Mustard was demonstrated (Br Heart J 1990;63:45-9).

Both a severely depressed right ventricular function and presence of severe tricuspid regurgitation were associated with significant lack of functional reserve with dobutamine infusion.   The authors performed a secondary analysis excluding those with severely depressed systolic function and were still able to show evidence of significant inability to augment preload in the remaining subjects.   Systemic vascular resistance was found to be higher in the atrial switch group.  Administration of volume, pacing, and dobutamine decreased SVR in both groups; however, the reduction in SVR after dobutamine was significantly lower in the atrial switch group than in normal controls.

ACHD media 1

Fig. 2 Indexed stroke volume (l/m2) at baseline, volume, pacing, dobutamine, in 49 patients with TGA after ABR and in 10 controls box plots express median, 25 and 75% quartiles, minimum, maximum and outliers ([1.5 interquartile length values)

 

National In-Hospital Outcomes of Pregnancy in Women with Single Ventricle Congenital Heart Disease.

Collins RT 2nd, Chang D, Sandlin A, Goudie A, Robbins JM.

Am J Cardiol. 2017 Feb 16. pii: S0002-9149(16)32014-8. doi: 10.1016/j.amjcard.2016.12.015. [Epub ahead of print]

PMID: 28242012

Similar articles

Select item 28205344

 

Take Home Points:

  • Pregnancy in patients with single ventricle physiology [most likely with Fontan palliation] is possible in the majority of affected individuals
  • CV complications in patients with single ventricle physiology however, were significantly greater than in matched controls and occurred in 25% of patients with SV CHD.
  • Arrhythmias were the most common cardiovascular complications.
  • No in-hospital maternal deaths occurred.
  • Three quarters of patients had successful vaginal deliveries.

 

 

Blanche CupidoCommentary from Dr Blanche Cupido (Cape Town, South Africa):  With advances in surgical and medical care over the last few decades, more women with complex congenital heart disease (CHD), including single ventricle CHD (SV), are now reaching childbearing age. Previously, these patients were advised against pregnancy. This study represents the largest cohort of pregnant SV patients. The authors assess in-hospital pregnancy related complications in patients with single ventricles and compare them to matched controls. A total of 282 patients with SV and 1405 matched controls were assessed from the US National Inpatient Sample (NIS) over a 15 year period.

 

Cardiovascular complications occurred in 24.8% of patients with SV CHD which was markedly greater than the control group (<1%). The cardiovascular complications always occurred in conjunction with obstetric complications.  Arrhythmias [atrial flutter and fibrillation, ventricular fibrillation and paroxysmal atrial tachycardia] represented the most common complications, occurring in 17.7% of cases. No in-hospital maternal deaths occurred.

 

Higher rates of non-cardiovascular obstetric complications [52% vs. 5%] was surprising suggesting a possible adverse interaction between SV physiology and the pregnancy. Obstetric complications included gestational diabetes, preterm labor and fetal growth restriction were seen in the group with single ventricle. Preterm delivery occurred in 18.1% of patients with SV vs. 8.5% in normal controls. Although this figure is lower than previously quoted literature, this study does not capture data related to spontaneous abortions. The average length of stay was merely 1.3 days more in the SV group (4.1 in SV and 2.8 in controls, p=0.03), though the cost of hospital stay was nearly double in the SV group ($30 787 vs $ 15 536, p<0.0001).

 

Three quarters of SV patients had successful vaginal deliveries. This supports earlier recommendations of trial of labor and vaginal delivery if, at baseline, the patient has an acceptable cardiovascular baseline. The study limitations were that it relied on ICD coding, does not take previous surgery or residual lesions into account and only considers in-hospital data. It is therefore only possible to presume that the majority of these women had Fontan circulations. One of the major limitations of the study is the inability to predict risk factors for adverse outcomes.

 

ACHD Feb 2017

  1. Body mass index in adult congenital heart disease.

Brida M, Dimopoulos K, Kempny A, Liodakis E, Alonso-Gonzalez R, Swan L, Uebing A, Baumgartner H, Gatzoulis MA, Diller GP.

Heart. 2017 Feb 25. pii: heartjnl-2016-310571. doi: 10.1136/heartjnl-2016-310571. [Epub ahead of print]

PMID: 28237971

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Select item 28237970

 

  1. Clinical predictors of length of stay in adults with congenital heart disease.

Cedars A, Benjamin L, Burns SV, Novak E, Amin A.

Heart. 2017 Feb 25. pii: heartjnl-2016-310841. doi: 10.1136/heartjnl-2016-310841. [Epub ahead of print]

PMID: 28237970

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Select item 28235129

 

  1. Isolated Aneurysms of the Membranous Ventricular Septum Without Residual Shunts: Systematic Review and Description of 3 Cases in Adults.

Abdul Jabbar A, Mufti O, Mazur W, Quraishi MB, Srivastava BK, Tivakaran V.

J Ultrasound Med. 2017 Feb 23. doi: 10.7863/ultra.16.02087. [Epub ahead of print] Review.

PMID: 28230264

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Select item 28121514

 

  1. Heart transplantation in adults with congenital heart disease.

Houyel L, To-Dumortier NT, Lepers Y, Petit J, Roussin R, Ly M, Lebret E, Fadel E, Hörer J, Hascoët S.

Arch Cardiovasc Dis. 2017 Feb 22. pii: S1875-2136(17)30028-1. doi: 10.1016/j.acvd.2017.01.002. [Epub ahead of print] Review.

PMID: 28237697

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Select item 28225219

 

  1. A great imitator in adult cardiology practice: congenitally corrected transposition of the great arteries.

Agarwal A, Samad F, Kalvin L, Bush M, Tajik AJ.

Congenit Heart Dis. 2017 Feb 22. doi: 10.1111/chd.12453. [Epub ahead of print]

PMID: 28225206

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Select item 28225202

 

  1. Value of Cardiovascular Magnetic Resonance Imaging in Noninvasive Risk Stratification in Tetralogy of Fallot.

Bokma JP, de Wilde KC, Vliegen HW, van Dijk AP, van Melle JP, Meijboom FJ, Zwinderman AH, Groenink M, Mulder BJ, Bouma BJ.

JAMA Cardiol. 2017 Feb 22. doi: 10.1001/jamacardio.2016.5818. [Epub ahead of print]

PMID: 28241248

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Select item 28082385

 

  1. Management of Pregnancy in Patients With Complex Congenital Heart Disease: A Scientific Statement for Healthcare Professionals From the American Heart Association.

Canobbio MM, Warnes CA, Aboulhosn J, Connolly HM, Khanna A, Koos BJ, Mital S, Rose C, Silversides C, Stout K; American Heart Association Council on Cardiovascular and Stroke Nursing; Council on Clinical Cardiology; Council on Cardiovascular Disease in the Young; Council on Functional Genomics and Translational Biology; and Council on Quality of Care and Outcomes Research..

Circulation. 2017 Feb 21;135(8):e50-e87. doi: 10.1161/CIR.0000000000000458. Review.

PMID: 28082385

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Select item 28223475

 

  1. The management of labour in women with cardiac disease: need for more evidence?

Cauldwell M, Cox M, Gatzoulis M, Nelson-Piercy C, O’Brien P, Roos-Hesselink JW, Thorne S, Walker F, Johnson MR.

BJOG. 2017 Feb 20. doi: 10.1111/1471-0528.14547. [Epub ahead of print] No abstract available.

PMID: 28218452

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Select item 28219978

 

  1. Correlates of posttraumatic stress disorder in adults with congenital heart disease.

Eslami B.

Congenit Heart Dis. 2017 Feb 20. doi: 10.1111/chd.12452. [Epub ahead of print]

PMID: 28217850

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Select item 28216473

 

  1. National In-Hospital Outcomes of Pregnancy in Women With Single Ventricle Congenital Heart Disease.

Collins RT 2nd, Chang D, Sandlin A, Goudie A, Robbins JM.

Am J Cardiol. 2017 Feb 16. pii: S0002-9149(16)32014-8. doi: 10.1016/j.amjcard.2016.12.015. [Epub ahead of print]

PMID: 28242012

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Select item 28205344

 

  1. Body Weights in Adults With Congenital Heart Disease and the Obesity Frequency.

Lerman JB, Parness IA, Shenoy RU.

Am J Cardiol. 2017 Feb 15;119(4):638-642. doi: 10.1016/j.amjcard.2016.10.050.

PMID: 27931725

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Select item 28198573

 

  1. Pregnancy outcomes in patients with pulmonary arterial hypertension associated with congenital heart disease.

Ladouceur M, Benoit L, Radojevic J, Basquin A, Dauphin C, Hascoet S, Moceri P, Bredy C, Iserin L, Gouton M, Nizard J.

Heart. 2017 Feb 15;103(4):287-292. doi: 10.1136/heartjnl-2016-310003.

PMID: 27511447

Similar articles

Select item 28196030

 

  1. Social Independence among Adult Congenital Heart Disease Patients in Japan.

Ochiai R, Ikeda Y, Kato H, Shiraishi I; Parents’ Association of Heart Disease Children..

Pediatr Int. 2017 Feb 15. doi: 10.1111/ped.13260. [Epub ahead of print]

PMID: 28199782

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Select item 28212920

 

  1. Cardiovascular and Ventilatory Consequences of Laparoscopic Surgery.

Atkinson TM, Giraud GD, Togioka BM, Jones DB, Cigarroa JE.

Circulation. 2017 Feb 14;135(7):700-710. doi: 10.1161/CIRCULATIONAHA.116.023262.

PMID: 28193800

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Select item 28189822

 

  1. High prevalence of fatigue in adults with a 22q11.2 deletion syndrome.

Vergaelen E, Claes S, Kempke S, Swillen A.

Am J Med Genet A. 2017 Feb 12. doi: 10.1002/ajmg.a.38094. [Epub ahead of print]

PMID: 28190295

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Select item 27959615

 

  1. Readiness for Transition to Adult Health Care for Young Adolescents with Congenital Heart Disease.

Stewart KT, Chahal N, Kovacs AH, Manlhiot C, Jelen A, Collins T, McCrindle BW.

Pediatr Cardiol. 2017 Feb 10. doi: 10.1007/s00246-017-1580-2. [Epub ahead of print]

PMID: 28184978

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Select item 28184976

 

  1. Decreased Diastolic Ventricular Kinetic Energy in Young Patients with Fontan Circulation Demonstrated by Four-Dimensional Cardiac Magnetic Resonance Imaging.

Sjöberg P, Heiberg E, Wingren P, Ramgren Johansson J, Malm T, Arheden H, Liuba P, Carlsson M.

Pediatr Cardiol. 2017 Feb 10. doi: 10.1007/s00246-016-1565-6. [Epub ahead of print]

PMID: 28184976

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Select item 28181314

 

  1. Transthoracic echocardiography study of congenitally corrected transposition of the great arteries.

Singh A, Singh G, Dhaliwal TS, Singh M.

J Clin Ultrasound. 2017 Feb 9. doi: 10.1002/jcu.22450. [Epub ahead of print]

PMID: 28182287

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Select item 28184975

 

  1. Determinants of Aortic Size and Stiffness and the Impact on Exercise Physiology in Patients After the Fontan Operation.

Ohuchi H, Hayama Y, Negishi J, Noritake K, Miyazaki A, Yamada O, Shiraishi I.

Int Heart J. 2017 Feb 7;58(1):73-80. doi: 10.1536/ihj.16-183.

PMID: 28111407 Free Article

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Select item 28153110

 

  1. Early Experience of Macitentan for Pulmonary Arterial Hypertension in Adult Congenital Heart Disease.

Herbert S, Gin-Sing W, Howard L, Tulloh RM.

Heart Lung Circ. 2017 Feb 6. pii: S1443-9506(17)30031-8. doi: 10.1016/j.hlc.2016.12.011. [Epub ahead of print]

PMID: 28237536

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Select item 28209388

 

  1. Preconception counseling, predicting risk and outcomes in women with mWHO 3 and 4 heart disease.

Cauldwell M, Ghonim S, Uebing A, Swan L, Steer PJ, Gatzoulis M, Johnson MR.

Int J Cardiol. 2017 Feb 4. pii: S0167-5273(17)30679-4. doi: 10.1016/j.ijcard.2017.02.003. [Epub ahead of print]

PMID: 28238509

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Select item 28161810

 

  1. Genetic basis of aortic valvular disease.

Koenig SN, Lincoln J, Garg V.

Curr Opin Cardiol. 2017 Feb 2. doi: 10.1097/HCO.0000000000000384. [Epub ahead of print]

PMID: 28157139

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Select item 28159944

 

  1. Are Olympic athletes free from cardiovascular diseases? Systematic investigation in 2352 participants from Athens 2004 to Sochi 2014.

Pelliccia A, Adami PE, Quattrini F, Squeo MR, Caselli S, Verdile L, Maestrini V, Di Paolo F, Pisicchio C, Ciardo R, Spataro A.

Br J Sports Med. 2017 Feb;51(4):238-243. doi: 10.1136/bjsports-2016-096961.

PMID: 28039126

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Select item 27720432

 

  1. Shone Complex: An Under-recognized Congenital Heart Disease With Substantial Morbidity in Adulthood.

Aslam S, Khairy P, Shohoudi A, Mercier LA, Dore A, Marcotte F, Miró J, Avila-Alonso P, Ibrahim R, Asgar A, Poirier N, Mongeon FP.

Can J Cardiol. 2017 Feb;33(2):253-259. doi: 10.1016/j.cjca.2016.09.005.

PMID: 27956040

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Select item 27650723

 

  1. [Striking Supply Gap in Adults with Congenital Heart Disease?]

Neidenbach R, Kaemmerer H, Pieper L, Ewert P, Schelling J.

Dtsch Med Wochenschr. 2017 Feb;142(4):301-303. doi: 10.1055/s-0042-121501. German. No abstract available.

PMID: 28235231

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Select item 28032368

 

  1. Healthcare needs of adolescents with congenital heart disease transitioning into adulthood: a Delphi survey of patients, parents, and healthcare providers.

Chen CW, Su WJ, Chiang YT, Shu YM, Moons P.

Eur J Cardiovasc Nurs. 2017 Feb;16(2):125-135. doi: 10.1177/1474515116643622.

PMID: 27045011

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  1. In defence of auscultation: a glorious future?

Thompson WR.

Heart Asia. 2017 Feb 1;9(1):44-47. doi: 10.1136/heartasia-2016-010796.

PMID: 28243316 Free PMC Article

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  1. The prevalence of sexual dysfunction and its association with quality of life in adults with congenital heart disease.

Neiman A, Ginde S, Earing MG, Bartz PJ, Cohen S.

Int J Cardiol. 2017 Feb 1;228:953-957. doi: 10.1016/j.ijcard.2016.11.192.

PMID: 27912205

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  1. Aortopathy in adults with tetralogy of Fallot has a negative impact on the left ventricle.

Shiina Y, Murakami T, Kawamatsu N, Niwa K.

Int J Cardiol. 2017 Feb 1;228:380-384. doi: 10.1016/j.ijcard.2016.11.252.

PMID: 27866031

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  1. Feasibility of low radiation dose retrospectively-gated cardiac CT for functional analysis in adult congenital heart disease.

Groves DW, Olivieri LJ, Shanbhag SM, Bronson KC, Yu JH, Nelson EA, Rollison SF, Stagliano MS, John AS, Kuehl K, Chen MY.

Int J Cardiol. 2017 Feb 1;228:180-183. doi: 10.1016/j.ijcard.2016.11.108.

PMID: 27865183 Free Article

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  1. The Clinical Use of Stress Echocardiography in Non-Ischaemic Heart Disease: Recommendations from the European Association of Cardiovascular Imaging and the American Society of Echocardiography.

Lancellotti P, Pellikka PA, Budts W, Chaudhry FA, Donal E, Dulgheru R, Edvardsen T, Garbi M, Ha JW, Kane GC, Kreeger J, Mertens L, Pibarot P, Picano E, Ryan T, Tsutsui JM, Varga A.

J Am Soc Echocardiogr. 2017 Feb;30(2):101-138. doi: 10.1016/j.echo.2016.10.016.

PMID: 28164802

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  1. Predictive value of biomarkers of hepatic fibrosis in adult Fontan patients.

Wu FM, Earing MG, Aboulhosn JA, Johncilla ME, Singh MN, Odze RD, Ukomadu C, Gauvreau K, Landzberg MJ, Valente AM; Alliance for Adult Research in Congenital Cardiology (AARCC) Investigators..

J Heart Lung Transplant. 2017 Feb;36(2):211-219. doi: 10.1016/j.healun.2016.07.011.

PMID: 27592026

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  1. A novel mouse model of high flow-induced pulmonary hypertension-surgically induced by right pulmonary artery ligation.

Zhang A, Wang H, Wang S, Huang X, Ye P, Du X, Xia J.

J Surg Res. 2017 Feb;208:132-139. doi: 10.1016/j.jss.2016.09.003.

PMID: 27993200

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  1. Clinical phenotypes and outcomes of heritable and sporadic pulmonary veno-occlusive disease: a population-based study.

Montani D, Girerd B, Jaïs X, Levy M, Amar D, Savale L, Dorfmüller P, Seferian A, Lau EM, Eyries M, Le Pavec J, Parent F, Bonnet D, Soubrier F, Fadel E, Sitbon O, Simonneau G, Humbert M.

Lancet Respir Med. 2017 Feb;5(2):125-134. doi: 10.1016/S2213-2600(16)30438-6.

PMID: 28087362

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  1. Acute arterial embolism of left lower extremity caused by paradoxical embolism in Ebstein’s anomaly: A case report.

Li JS, Ma J, Yan ZX, Cheng DM, Chang L, Zhang HC, Liu JY.

Medicine (Baltimore). 2017 Feb;96(5):e5901. doi: 10.1097/MD.0000000000005901.

PMID: 28151866 Free PMC Article

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Select item 28035386

 

  1. Limited Ventricular Preload is the Main Reason for Reduced Stress Reserve After Atrial Baffle Repair.

Eicken A, Michel J, Hager A, Tanase D, Kaemmerer H, Cleuziou J, Hess J, Ewert P.

Pediatr Cardiol. 2017 Feb;38(2):353-361. doi: 10.1007/s00246-016-1521-5.

PMID: 27885445

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Select item 27882423

 

  1. Cardio-Ankle Vascular Index (CAVI) and Plasma Transforming Growth Factor-β1 (TGF-β1) Level Correlate with Aortopathy in Adults with Repaired Tetralogy of Fallot.

Shiina Y, Niwa K.

Pediatr Cardiol. 2017 Feb;38(2):338-343. doi: 10.1007/s00246-016-1519-z.

PMID: 27882423

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Select item 27878633

 

  1. Global Deformation Parameters Response to Exercise in Adolescents with Repaired Tetralogy of Fallot.

Mese T, Guven B, Yilmazer MM, Demirol M, Çoban Ş, Karadeniz C.

Pediatr Cardiol. 2017 Feb;38(2):362-367. doi: 10.1007/s00246-016-1522-4.

PMID: 27878628

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  1. Uteroplacental Doppler flow and pregnancy outcome in women with tetralogy of Fallot.

Kampman MA, Siegmund AS, Bilardo CM, van Veldhuisen DJ, Balci A, Oudijk MA, Groen H, Mulder BJ, Roos-Hesselink JW, Sieswerda G, de Laat MW, Sollie-Szarynska KM, Pieper PG; ZAHARA investigators..

Ultrasound Obstet Gynecol. 2017 Feb;49(2):231-239. doi: 10.1002/uog.15938.

PMID: 27071979

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  1. International Recommendations for Electrocardiographic Interpretation in Athletes.

Sharma S, Drezner JA, Baggish A, Papadakis M, Wilson MG, Prutkin JM, La Gerche A, Ackerman MJ, Borjesson M, Salerno JC, Asif IM, Owens DS, Chung EH, Emery MS, Froelicher VF, Heidbuchel H, Adamuz C, Asplund CA, Cohen G, Harmon KG, Marek JC, Molossi S, Niebauer J, Pelto HF, Perez MV, Riding NR, Saarel T, Schmied CM, Shipon DM, Stein R, Vetter VL, Pelliccia A, Corrado D.

J Am Coll Cardiol. 2017 Feb 28;69(8):1057-1075. doi: 10.1016/j.jacc.2017.01.015. Review.

PMID: 28231933

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  1. Long-acting PDE5 inhibitor tadalafil prevents early doxorubicin-induced left ventricle diastolic dysfunction in juvenile mice: potential role of cytoskeletal proteins.

Nagiub M, Filippone S, Durrant D, Das A, Kukreja RC.

Can J Physiol Pharmacol. 2017 Feb 26:1-10. doi: 10.1139/cjpp-2016-0551. [Epub ahead of print]

PMID: 28238269

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  1. The Burden of Early Phenotypes and the Influence of Wall Thickness in Hypertrophic Cardiomyopathy Mutation Carriers: Findings From the HCMNet Study.

Ho CY, Day SM, Colan SD, Russell MW, Towbin JA, Sherrid MV, Canter CE, Jefferies JL, Murphy AM, Cirino AL, Abraham TP, Taylor M, Mestroni L, Bluemke DA, Jarolim P, Shi L, Sleeper LA, Seidman CE, Orav EJ; HCMNet Investigators..

JAMA Cardiol. 2017 Feb 22. doi: 10.1001/jamacardio.2016.5670. [Epub ahead of print]

PMID: 28241245

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Select item 28238794

 

  1. Body Weights in Adults With Congenital Heart Disease and the Obesity Frequency.

Lerman JB, Parness IA, Shenoy RU.

Am J Cardiol. 2017 Feb 15;119(4):638-642. doi: 10.1016/j.amjcard.2016.10.050.

PMID: 27931725

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Select item 28201824

 

  1. Proximal aortic stiffening in Turner patients may be present before dilation can be detected: a segmental functional MRI study.

Devos DG, De Groote K, Babin D, Demulier L, Taeymans Y, Westenberg JJ, Van Bortel L, Segers P, Achten E, De Schepper J, Rietzschel E.

J Cardiovasc Magn Reson. 2017 Feb 13;19(1):27. doi: 10.1186/s12968-017-0331-0.

PMID: 28222756 Free PMC Article

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  1. Magnetic resonance imaging 4-D flow-based analysis of aortic hemodynamics in Turner syndrome.

Arnold R, Neu M, Hirtler D, Gimpel C, Markl M, Geiger J.

Pediatr Radiol. 2017 Feb 9. doi: 10.1007/s00247-016-3767-8. [Epub ahead of print]

PMID: 28184962

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Select item 28178426

 

  1. Burden of Arrhythmia in Pregnancy.

Vaidya VR, Arora S, Patel N, Badheka AO, Patel N, Agnihotri K, Billimoria Z, Turakhia MP, Friedman PA, Madhavan M, Kapa S, Noseworthy PA, Cha YM, Gersh B, Asirvatham SJ, Deshmukh AJ.

Circulation. 2017 Feb 7;135(6):619-621. doi: 10.1161/CIRCULATIONAHA.116.026681. No abstract available.

PMID: 28154000

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  1. Aerobic exercise in anthracycline-induced cardiotoxicity: a systematic review of current evidence and future directions.

Chen JJ, Wu PT, Middlekauff HR, Nguyen KL.

Am J Physiol Heart Circ Physiol. 2017 Feb 1;312(2):H213-H222. doi: 10.1152/ajpheart.00646.2016. Review.

PMID: 27923793

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  1. Translational Advances in the Field of Pulmonary Hypertension. Focusing on Developmental Origins and Disease Inception for the Prevention of Pulmonary Hypertension.

Maron BA, Abman SH.

Am J Respir Crit Care Med. 2017 Feb 1;195(3):292-301. doi: 10.1164/rccm.201604-0882PP. No abstract available.

PMID: 27854133

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  1. An Unusual Cause of Hemopericardium 22 Years After a Fontan Procedure.

Martin BJ, Seaman C, Windram JD, Rebeyka IM.

Ann Thorac Surg. 2017 Feb;103(2):e187-e189. doi: 10.1016/j.athoracsur.2016.06.108.

PMID: 28109386

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Select item 28109385

 

  1. Assessing utility of exercise test in determining exercise prescription in adolescent and adult patients with repaired tetralogy of fallot.

Yang MC, Chen CA, Chiu HH, Wang JK, Lin MT, Chiu SN, Lu CW, Huang SC, Wu MH.

Heart Vessels. 2017 Feb;32(2):201-207. doi: 10.1007/s00380-016-0849-3.

PMID: 27272896

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Select item 27255116

 

  1. Late Wall Thickening and Calcification in Patients After Kawasaki Disease.

Tsujii N, Tsuda E, Kanzaki S, Ishizuka J, Nakashima K, Kurosaki K.

J Pediatr. 2017 Feb;181:167-171.e2. doi: 10.1016/j.jpeds.2016.10.026.

PMID: 27837949

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Select item 27816222

 

  1. Limited Ventricular Preload is the Main Reason for Reduced Stress Reserve After Atrial Baffle Repair.

Eicken A, Michel J, Hager A, Tanase D, Kaemmerer H, Cleuziou J, Hess J, Ewert P.

Pediatr Cardiol. 2017 Feb;38(2):353-361. doi: 10.1007/s00246-016-1521-5.

PMID: 27885445

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CHD Surgery Featured Articles of February 2017

Can Fontan Conversion for Patients without Late Fontan Complications be Justified?
Higashida A, Hoashi T, Kagisaki K, Shimada M, Ohuchi H, Shiraishi I, Ichikawa H.
Ann Thorac Surg. 2017 Feb 24. pii: S0003-4975(16)31796-9. doi: 10.1016/j.athoracsur.2016.11.062. [Epub ahead of print] PMID: 28242080
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Select item 28242079
 

Take Home Points:

  • Late Fontan conversion may improve atrial tachyarrhythmias but not protein-losing enteropathy.
  • Patients with or without these complications may demonstrate improved cardiac function after Fontan conversion, at least in the medium term.

jeremy-herrmannCommentary from Dr. Jeremy Herrmann (Indianapolis), section editor of Congenital Heart Surgery Journal Watch: This article offers a slightly different take on outcomes of patients who undergo Fontan conversion, specifically with regard to patients who lack protein-losing enteropathy (PLE) or atrial tachyarrhythmia (AT) as primary indications for conversion. They classified PLE and AT as “late Fontan complications”.

They included 32 patients who underwent Fontan conversion between 1991 and 2012 at their institution. Of these, 25 patients underwent conversion for PLE or AT (4 and 24 patients, respectively). Of the remaining 7 patients, 2 underwent conversion for thrombus related to Fontan pathway; the indications for the other 5 were not provided. Antiarrhythmia procedures (e.g., biatrial or right atrial cryoablation) were performed as indicated. The mean follow-up periods were 6.2 years for the late complication group and 4.6 years for the group without. Overall survival at 10 years did not differ between the groups. In terms of outcomes relating to the late complications, 67% of patients with preoperative AT were free of it at last follow-up, whereas PLE persisted in all. None of the patients without AT or PLE preoperatively developed these during the follow-up period. The cardiac index did significantly improve in both groups, as did NYHA classification for the group with pre-existing AT or PLE. Peak oxygen consumption did not improve in either group, however.

There are several important limitations of the study. The sample size is small and the follow-up period is short. The authors only included AT and PLE as late Fontan complications, and it could certainly be argued that thrombotic events could be categorized as same. Specific details of AT and PLE were diagnosed as well as how the cryoablation lesion sets were performed are not clearly described.

The authors conclude that Fontan conversion is associated with improved cardiac output and not associated with new-onset AT and PLE. Fontan conversion with cryoablation was moderately successful in eliminating pre-existing AT though completely unsuccessful in eliminating PLE. Though their findings suggest patients without these complications tend to do well with Fontan conversion, the procedure may not be justified in asymptomatic patients. This study also demonstrates how inconsistent definitions of symptoms and degree can complicate outcomes research.

 

Complete Repair of Tetralogy of Fallot in the Neonatal versus Non-neonatal Period: A Meta-analysis.
Loomba RS, Buelow MW, Woods RK.
Pediatr Cardiol. 2017 Feb 11. doi: 10.1007/s00246-017-1579-8. [Epub ahead of print] Review.
PMID: 28190140
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Select item 28187018

 

Take Home Points:

  • Initial palliation with a systemic-to-PA shunt and delayed repair of tetralogy of Fallot may be associated with lower mortality and morbidity compared to a strategy of complete neonatal repair.
  • This study attempts to provide a higher level of evidence in meta-analysis form, though limited studies met inclusion criteria for pooled analysis.

Commentary from Dr. Jeremy Herrmann (Indianapolis), section editor of Congenital Heart Surgery Journal Watch: The decision of whether to pursue full neonatal repair or to palliate with a shunt and delay repair for tetralogy of Fallot patients remains a recurring issue that frequently relates to institutional experience. In this study, the authors review the current literature in meta-analysis form in order to attempt to determine which pathway offers better outcomes as no randomized data exist. In all, 8 studies with 3,858 patients were included, though the analysis of each individual parameter included as few as 2 studies.

The authors found that delayed repair after neonatal palliation (typically with a systemic-to-pulmonary artery shunt) was associated with a lower risk of mortality, shorter hospital and ICU lengths of stay, less risk of arrhythmia, less need for delayed sternal closure, and less transannular patch utilization compared to neonatal repair. The groups were similar in risk of use of postoperative ECMO and need for re-intervention.

This study represents a potentially higher level of evidence that the variety of retrospective single and even multi-institutional analyses. However, there are several important limitations of the study. It is unclear how management pathways were chosen, particularly in terms of underlying anatomic features. The follow-up periods of the studies were not listed but appear to be short-term. Specific surgeon or institutional preferences were unable to be accounted for and could present a source of strong selection bias.

The authors conclude that delayed repair of Tetralogy of Fallot after initial palliation with a shunt should be preferred to a strategy of complete neonatal repair. It is difficult to establish concrete conclusions from what in several cases are small pools of studies. However, their findings not only muddy the debate about which strategy is superior but also support a more rigorous effort to determine which strategy is better in the short- and long-term.

 

CHD Surgery Feb 2017

  1. Evaluation of commissural malalignment of aortic-pulmonary sinus using cardiac CT for arterial switch operation: comparison with transthoracic echocardiography.

Bang JH, Park JJ, Goo HW.

Pediatr Radiol. 2017 Feb 27. doi: 10.1007/s00247-017-3786-0. [Epub ahead of print]

PMID: 28243677

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Select item 28237971

 

  1. Reconstruction of the pulmonary posterior wall using in situ autologous tissue for the treatment of pulmonary atresia with ventricular septal defect.

Fan C, Yang Y, Xiong L, Yin N, Wu Q, Tang M, Yang J.

J Cardiothorac Surg. 2017 Feb 23;12(1):12. doi: 10.1186/s13019-017-0578-4.

PMID: 28231853 Free PMC Article

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Select item 28230264

 

  1. Functional Status and Quality of Life in Survivors of Extracorporeal Membrane Oxygenation After the Norwood Operation.

Friedland-Little JM, Uzark K, Yu S, Lowery R, Aiyagari R, Hirsch-Romano JC.

Ann Thorac Surg. 2017 Feb 18. pii: S0003-4975(16)31617-4. doi: 10.1016/j.athoracsur.2016.11.015. [Epub ahead of print]

PMID: 28223051

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  1. Increased Atrial β-Adrenergic Receptors and GRK-2 Gene Expression Can Play a Fundamental Role in Heart Failure After Repair of Congenital Heart Disease with Cardiopulmonary Bypass.

Oliveira MS, Carmona F, Vicente WV, Manso PH, Mata KM, Celes MR, Campos EC, Ramos SG.

Pediatr Cardiol. 2017 Feb 18. doi: 10.1007/s00246-017-1573-1. [Epub ahead of print]

PMID: 28214967

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Select item 28212589

 

  1. Utility of a standardized postcardiopulmonary bypass epicardial echocardiography protocol for stage I Norwood palliation.

Stern KW, Gauvreau K, Emani S, Geva T.

Congenit Heart Dis. 2017 Feb 16. doi: 10.1111/chd.12450. [Epub ahead of print]

PMID: 28205344

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Select item 28221991

 

  1. Oral Triiodothyronine for Infants and Children Undergoing Cardiopulmonary Bypass.

Marwali EM, Boom CE, Budiwardhana N, Fakhri D, Roebiono PS, Santoso A, Sastroasmoro S, Slee A, Portman MA.

Ann Thorac Surg. 2017 Feb 6. pii: S0003-4975(17)30014-0. doi: 10.1016/j.athoracsur.2017.01.001. [Epub ahead of print]

PMID: 28185643

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Select item 28168740

 

  1. Decreased biventricular longitudinal strain shortly after congenital heart defect surgery.

de Boer JM, Kuipers IM, Klitsie LM, Blom NA, Ten Harkel AD.

Echocardiography. 2017 Feb 6. doi: 10.1111/echo.13456. [Epub ahead of print]

PMID: 28168740

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Select item 28237536

 

  1. External stenting: A reliable technique to relieve airway obstruction in small children.

Ando M, Nagase Y, Hasegawa H, Takahashi Y.

J Thorac Cardiovasc Surg. 2017 Feb 3. pii: S0022-5223(17)30150-2. doi: 10.1016/j.jtcvs.2016.12.041. [Epub ahead of print]

PMID: 28242014

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Select item 28151929

 

  1. Anesthesia and Databases: Pediatric Cardiac Disease as a Role Model.

Vener DF, Pasquali SK, Mossad EB.

Anesth Analg. 2017 Feb;124(2):572-581. doi: 10.1213/ANE.0000000000001448.

PMID: 28099323

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Select item 28109384

 

  1. Failing Systemic Right Ventricles With Persistent Pulmonary Hypertension: Candidates for Ventricular Assist Devices as Destination Therapy?

Loup O, Wustmann K, Martinelli MV, Schwerzmann M, Mohacsi P, Carrel TP, Kadner A.

Ann Thorac Surg. 2017 Feb;103(2):e179-e181. doi: 10.1016/j.athoracsur.2016.03.080.

PMID: 28109384

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Select item 28024650

 

  1. Pulmonary Valve Replacement With a Trifecta Valve Is Associated With Reduced Transvalvular Gradient.

Gulack BC, Benrashid E, Jaquiss RD, Lodge AJ.

Ann Thorac Surg. 2017 Feb;103(2):655-662. doi: 10.1016/j.athoracsur.2016.06.018.

PMID: 27570156 Free PMC Article

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Select item 28011082

 

  1. Topical and low-dose intravenous tranexamic acid in cyanotic cardiac surgery.

Patel J, Prajapati M, Patel H, Gandhi H, Deodhar S, Pandya H.

Asian Cardiovasc Thorac Ann. 2017 Feb;25(2):118-122. doi: 10.1177/0218492316688416.

PMID: 28068786

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Select item 27925466

 

  1. Trends and outcomes in neonatal cardiac surgery for congenital heart disease in Japan from 1996 to 2010.

Hasegawa T, Masuda M, Okumura M, Arai H, Kobayashi J, Saiki Y, Tanemoto K, Nishida H, Motomura N.

Eur J Cardiothorac Surg. 2017 Feb 1;51(2):301-307. doi: 10.1093/ejcts/ezw302. No abstract available.

PMID: 28186248

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Select item 27045011

 

  1. Simultaneous repair of pectus excavatum and pulmonary valve implantation years after complete repair of tetralogy of Fallot.

Tuncer E, Vuran AC, Ozyuksel A, Yeginsu A, Ceyran H.

Gen Thorac Cardiovasc Surg. 2017 Feb;65(2):127-129. doi: 10.1007/s11748-015-0578-z.

PMID: 26232358

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Select item 28243316

 

  1. Outcomes of Subaortic Obstruction Resection in Children.

Donald JS, Naimo PS, d’Udekem Y, Richardson M, Bullock A, Weintraub RG, Brizard CP, Konstantinov IE.

Heart Lung Circ. 2017 Feb;26(2):179-186. doi: 10.1016/j.hlc.2016.05.120.

PMID: 27522512

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Select item 27687644

 

  1. Isolated heart transplant and combined heart-liver transplant in adult congenital heart disease patients: Insights from the united network of organ sharing.

Bradley EA, Pinyoluksana KO, Moore-Clingenpeel M, Miao Y, Daniels C.

Int J Cardiol. 2017 Feb 1;228:790-795. doi: 10.1016/j.ijcard.2016.11.121.

PMID: 27888756

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Select item 27866031

 

  1. Survival and cardiovascular events after coarctation-repair in long-term follow-up (COAFU): Predictive value of clinical variables.

Bambul Heck P, Pabst von Ohain J, Kaemmerer H, Ewert P, Hager A.

Int J Cardiol. 2017 Feb 1;228:347-351. doi: 10.1016/j.ijcard.2016.11.164.

PMID: 27866026

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Select item 27866021

 

  1. Preoperative evaluation of coronary artery fistula using dual-source computed tomography.

Shi K, Gao HL, Yang ZG, Zhang Q, Liu X, Guo YK.

Int J Cardiol. 2017 Feb 1;228:80-85. doi: 10.1016/j.ijcard.2016.11.169.

PMID: 27863365

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Select item 28145049

 

  1. Systemic inflammatory response syndrome after pediatric congenital heart surgery: Incidence, risk factors, and clinical outcome.

Boehne M, Sasse M, Karch A, Dziuba F, Horke A, Kaussen T, Mikolajczyk R, Beerbaum P, Jack T.

J Card Surg. 2017 Feb;32(2):116-125. doi: 10.1111/jocs.12879.

PMID: 27928843

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Select item 27885752

 

  1. Right Aortic Arch with a Retroesophageal Left Subclavian Artery and an Anomalous Origin of the Pulmonary Artery from the Aorta.

Jeon CS, Shim MS, Yang JH, Jun TG.

Korean J Thorac Cardiovasc Surg. 2017 Feb;50(1):44-46. doi: 10.5090/kjtcs.2017.50.1.44.

PMID: 28180103 Free PMC Article

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Select item 28087362

 

  1. Kaolin-activated thromboelastography and standard coagulation assays in cyanotic and acyanotic infants undergoing complex cardiac surgery: a prospective cohort study.

Rizza A, Ricci Z, Pezzella C, Favia I, Di Felice G, Ranucci M, Cogo P.

Paediatr Anaesth. 2017 Feb;27(2):170-180. doi: 10.1111/pan.13038.

PMID: 27935164

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Select item 27901294

 

  1. Performance of functional fibrinogen thromboelastography in children undergoing congenital heart surgery.

Gautam NK, Cai C, Pawelek O, Rafique MB, Cattano D, Pivalizza EG.

Paediatr Anaesth. 2017 Feb;27(2):181-189. doi: 10.1111/pan.13048.

PMID: 27901294

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Select item 28039526

 

  1. Surgical Repair of Ventricular Septal Defect; Contemporary Results and Risk Factors for a Complicated Course.

Schipper M, Slieker MG, Schoof PH, Breur JM.

Pediatr Cardiol. 2017 Feb;38(2):264-270. doi: 10.1007/s00246-016-1508-2.

PMID: 27872996

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Select item 27872995

 

  1. Outcomes of Tracheostomy in Children Requiring Surgery for Congenital Heart Disease.

Ortmann LA, Manimtim WM, Lachica CI.

Pediatr Cardiol. 2017 Feb;38(2):296-301. doi: 10.1007/s00246-016-1512-6.

PMID: 27872994

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Select item 27872993

 

  1. Mind the Heart: Delirium in Children Following Cardiac Surgery for Congenital Heart Disease.

Leroy PL, Schieveld JN.

Pediatr Crit Care Med. 2017 Feb;18(2):196-198. doi: 10.1097/PCC.0000000000001038. No abstract available.

PMID: 28157798

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Select item 27977539

 

  1. Delirium in Children After Cardiac Bypass Surgery.

Patel AK, Biagas KV, Clarke EC, Gerber LM, Mauer E, Silver G, Chai P, Corda R, Traube C.

Pediatr Crit Care Med. 2017 Feb;18(2):165-171. doi: 10.1097/PCC.0000000000001032.

PMID: 27977539

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Select item 27849657

 

  1. Long-Term Follow-Up on Health-Related Quality of Life After Mechanical Circulatory Support in Children.

Fleck TP, Dangel G, Bächle F, Benk C, Grohmann J, Kroll J, Siepe M, Höhn R, Kirschner J, Beyersdorf F, Stiller B.

Pediatr Crit Care Med. 2017 Feb;18(2):176-182. doi: 10.1097/PCC.0000000000001019.

PMID: 27849657

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Select item 27849656

 

  1. Can Fontan Conversion For Patients Without Late Fontan Complications Be Justified?

Higashida A, Hoashi T, Kagisaki K, Shimada M, Ohuchi H, Shiraishi I, Ichikawa H.

Ann Thorac Surg. 2017 Feb 24. pii: S0003-4975(16)31796-9. doi: 10.1016/j.athoracsur.2016.11.062. [Epub ahead of print]

PMID: 28242080

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Select item 28242079

 

  1. Long-Term Follow-Up After The Ross Procedure: A Single Center 22-Year Experience.

Schneider AW, Putter H, Klautz RJ, Bruggemans EF, Holman ER, Bökenkamp R, Hazekamp MG.

Ann Thorac Surg. 2017 Feb 24. pii: S0003-4975(16)31798-2. doi: 10.1016/j.athoracsur.2016.11.064. [Epub ahead of print]

PMID: 28242079

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  1. Cardiac transplantation in a neonate – First case in Switzerland and European Overview.

Schweiger M, Stiasny B, Immer F, Bürki C, Schmiady M, Dave H, Cavigelli-Brunner A, Kretschmar O, Cannizzaro V, Hübler M.

Clin Transplant. 2017 Feb 24. doi: 10.1111/ctr.12935. [Epub ahead of print]

PMID: 28235145

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  1. Peritoneal Dialysis vs Furosemide for Prevention of Fluid Overload in Infants After Cardiac Surgery: A Randomized Clinical Trial.

Kwiatkowski DM, Goldstein SL, Cooper DS, Nelson DP, Morales DL, Krawczeski CD.

JAMA Pediatr. 2017 Feb 20. doi: 10.1001/jamapediatrics.2016.4538. [Epub ahead of print]

PMID: 28241247

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  1. Anomalous Coronary Arteries and Myocardial Bridges: Risk Stratification in Children Using Novel Cardiac Catheterization Techniques.

Agrawal H, Molossi S, Alam M, Sexson-Tejtel SK, Mery CM, McKenzie ED, Fraser CD Jr, Qureshi AM.

Pediatr Cardiol. 2017 Feb 18. doi: 10.1007/s00246-016-1559-4. [Epub ahead of print]

PMID: 28214966

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  1. Surgical Correction of Aberrant Right Coronary Anomalies Stranding an Aortic Commissure with and Without Unroofing.

Abdelhady K, Durgam S, Elzein C, Ilbawi MN, Rhoiney D, Massad MG.

Pediatr Cardiol. 2017 Feb 18. doi: 10.1007/s00246-017-1581-1. [Epub ahead of print]

PMID: 28214965

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  1. Speckle Tracking in ALCAPA Patients After Surgical Repair as Predictor of Residual Coronary Disease.

Castaldi B, Vida V, Reffo E, Padalino M, Daniels Q, Stellin G, Milanesi O.

Pediatr Cardiol. 2017 Feb 18. doi: 10.1007/s00246-017-1583-z. [Epub ahead of print]

PMID: 28214964

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  1. Routine Application of Bloodless Priming in Neonatal Cardiopulmonary Bypass: A 3-Year Experience.

Boettcher W, Sinzobahamvya N, Miera O, Redlin M, Dehmel F, Cho MY, Murin P, Berger F, Photiadis J.

Pediatr Cardiol. 2017 Feb 14. doi: 10.1007/s00246-017-1585-x. [Epub ahead of print]

PMID: 28197644

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  1. Concomitant pulsatile and continuous flow VAD in biventricular and univentricular physiology: a comparison study with a numerical model.

Di Molfetta A, Ferrari G, Iacobelli R, Filippelli S, Guccione P, Fresiello L, Perri G, Amodeo A.

Int J Artif Organs. 2017 Feb 11:0. doi: 10.5301/ijao.5000562. [Epub ahead of print]

PMID: 28218352

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  1. Predicting Fluid Responsiveness in Children Undergoing Cardiac Surgery After Cardiopulmonary Bypass.

Favia I, Romagnoli S, Di Chiara L, Ricci Z.

Pediatr Cardiol. 2017 Feb 11. doi: 10.1007/s00246-017-1582-0. [Epub ahead of print]

PMID: 28190141

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  1. Complete Repair of Tetralogy of Fallot in the Neonatal Versus Non-neonatal Period: A Meta-analysis.

Loomba RS, Buelow MW, Woods RK.

Pediatr Cardiol. 2017 Feb 11. doi: 10.1007/s00246-017-1579-8. [Epub ahead of print] Review.

PMID: 28190140

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  1. Five-year experience with immediate extubation after arterial switch operations for transposition of great arteries.

Varghese J, Kutty S, Bisselou Moukagna KS, Craft M, Abdullah I, Hammel JM.

Eur J Cardiothorac Surg. 2017 Feb 10. doi: 10.1093/ejcts/ezw424. [Epub ahead of print] No abstract available.

PMID: 28199509

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  1. Association Between Hematologic and Inflammatory Markers and 31 Thrombotic and Hemorrhagic Events in Berlin Heart Excor Patients.

Iyengar A, Hung ML, Asanad K, Kwon OJ, Jackson NJ, Reemtsen BL, Federman MD, Biniwale RM.

Pediatr Cardiol. 2017 Feb 10. doi: 10.1007/s00246-017-1578-9. [Epub ahead of print]

PMID: 28184979

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  1. Long-term pediatric ventricular assist device therapy: a case report of 2100+ days of support.

Purkey NJ, Lin A, Murray JM, Gowen M, Shuttleworth P, Maeda K, Almond CS, Rosenthal DN, Chen S.

ASAIO J. 2017 Feb 9. doi: 10.1097/MAT.0000000000000546. [Epub ahead of print]

PMID: 28195883

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  1. Clinical application of three-dimensional printing to the management of complex univentricular hearts with abnormal systemic or pulmonary venous drainage.

McGovern E, Kelleher E, Snow A, Walsh K, Gadallah B, Kutty S, Redmond JM, McMahon CJ.

Cardiol Young. 2017 Feb 6:1-9. doi: 10.1017/S104795111600281X. [Epub ahead of print]

PMID: 28162139

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  1. Allograft Heart Valves: Current Aspects and Future Applications.

Lisy M, Kalender G, Schenke-Layland K, Brockbank KG, Biermann A, Stock UA.

Biopreserv Biobank. 2017 Feb 2. doi: 10.1089/bio.2016.0070. [Epub ahead of print]

PMID: 28151005

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  1. Scimitar Syndrome-Complex Surgical Revision 3 Decades After Repair.

Abadeer MN, Stuth EA, Kouretas PC, Ginde S, Jacobsen R, Woods RK.

Ann Thorac Surg. 2017 Feb;103(2):e183-e185. doi: 10.1016/j.athoracsur.2016.07.056.

PMID: 28109385

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  1. Completeness and Accuracy of Local Clinical Registry Data for Children Undergoing Heart Surgery.

Nathan M, Jacobs ML, Gaynor JW, Newburger JW, Dunbar Masterson C, Lambert LM, Hollenbeck-Pringle D, Trachtenberg FL, White O, Anderson BR, Bell MC, Burch PT, Graham EM, Kaltman JR, Kanter KR, Mery CM, Pizarro C, Schamberger MS, Taylor MD, Jacobs JP, Pasquali SK; Pediatric Heart Network Investigators..

Ann Thorac Surg. 2017 Feb;103(2):629-636. doi: 10.1016/j.athoracsur.2016.06.111.

PMID: 27726857

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  1. Therapy of acute kidney injury in the perioperative setting.

Romagnoli S, Ricci Z, Ronco C.

Curr Opin Anaesthesiol. 2017 Feb;30(1):92-99. doi: 10.1097/ACO.0000000000000424.

PMID: 27841787

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  1. Long-term results after repair of anomalous origin of left coronary artery from the pulmonary artery: Takeuchi repair versus coronary transfer.

Neumann A, Sarikouch S, Bobylev D, Meschenmoser L, Breymann T, Westhoff-Bleck M, Scheid M, Tzanavaros I, Bertram H, Beerbaum P, Haverich A, Boethig D, Horke A.

Eur J Cardiothorac Surg. 2017 Feb 1;51(2):308-315. doi: 10.1093/ejcts/ezw268. No abstract available.

PMID: 28186291

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  1. Results of pericardiectomy for constrictive pericarditis : Single-center experience.

Ak K, Demirbaş E, Ataş H, Birkan Y, Akalın F, Cobanoglu A, Arsan S, İsbir S.

Herz. 2017 Feb;42(1):75-83. doi: 10.1007/s00059-016-4436-2.

PMID: 27255116

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  1. Perioperative hypothermia in neonatal intensive care unit patients: effectiveness of a thermoregulation intervention and associated risk factors.

Engorn BM, Kahntroff SL, Frank KM, Singh S, Harvey HA, Barkulis CT, Barnett AM, Olambiwonnu OO, Heitmiller ES, Greenberg RS.

Paediatr Anaesth. 2017 Feb;27(2):196-204. doi: 10.1111/pan.13047.

PMID: 27917566

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  1. Post-cardiotomy Rescue Extracorporeal Cardiopulmonary Resuscitation in Neonates with Single Ventricle After Intractable Cardiac Arrest: Attrition After Hospital Discharge and Predictors of Outcome.

Polimenakos AC, Rizzo V, El-Zein CF, Ilbawi MN.

Pediatr Cardiol. 2017 Feb;38(2):314-323. doi: 10.1007/s00246-016-1515-3.

PMID: 27885446

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  1. Influence of Transplant Center Procedural Volume on Survival Outcomes of Heart Transplantation for Children Bridged with Mechanical Circulatory Support.

Hsieh A, Tumin D, McConnell PI, Galantowicz M, Tobias JD, Hayes D Jr.

Pediatr Cardiol. 2017 Feb;38(2):280-288. doi: 10.1007/s00246-016-1510-8.

PMID: 27882424

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  1. Outcomes of Tracheostomy in Children Requiring Surgery for Congenital Heart Disease.

Ortmann LA, Manimtim WM, Lachica CI.

Pediatr Cardiol. 2017 Feb;38(2):296-301. doi: 10.1007/s00246-016-1512-6.

PMID: 27872994

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  1. Long-Term Follow-Up on Health-Related Quality of Life After Mechanical Circulatory Support in Children.

Fleck TP, Dangel G, Bächle F, Benk C, Grohmann J, Kroll J, Siepe M, Höhn R, Kirschner J, Beyersdorf F, Stiller B.

Pediatr Crit Care Med. 2017 Feb;18(2):176-182. doi: 10.1097/PCC.0000000000001019.

PMID: 27849657

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  1. Bedside Ultrasound for the Diagnosis of Abnormal Diaphragmatic Motion in Children After Heart Surgery.

Gil-Juanmiquel L, Gratacós M, Castilla-Fernández Y, Piqueras J, Baust T, Raguer N, Balcells J, Perez-Hoyos S, Abella RF, Sanchez-de-Toledo J.

Pediatr Crit Care Med. 2017 Feb;18(2):159-164. doi: 10.1097/PCC.0000000000001015.

PMID: 27801709

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  1. Transient severe tricuspid regurgitation after transplantation of an extremely oversized donor heart in a child-Does size matter? A case report.

Birnbaum J, Ulrich SM, Schramm R, Hagl C, Lehner A, Fischer M, Haas NA, Heineking B.

Pediatr Transplant. 2017 Feb;21(1). doi: 10.1111/petr.12863.

PMID: 27925367

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  1. Regional variation in the use of 1A status exceptions for pediatric heart transplant candidates: is this equitable?

Godown J, McKane M, Wujcik KA, Mettler BA, Dodd DA.

Pediatr Transplant. 2017 Feb;21(1). doi: 10.1111/petr.12784.

PMID: 27549918

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  1. Inflammatory cytokine response and cardiac troponin I changes in cardiopulmonary bypass using two cardioplegia solutions; del Nido and modified St. Thomas’: a randomized controlled trial.

Gorjipour F, Dehaki MG, Totonchi Z, Hajimiresmaiel SJ, Azarfarin R, Pazoki-Toroudi H, Mahdavi M, Korbi M, Dehaki MG, Soltani B, Gorjipour F.

Perfusion. 2017 Feb 1:267659117691119. doi: 10.1177/0267659117691119. [Epub ahead of print]

PMID: 28152655

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  1. Isolated facial nerve palsy after arterial switch operation: A rarity.

Sahu MK, Alam I, Singh SP, Menon R, Talwar S.

Ann Pediatr Cardiol. 2017 Jan-Apr;10(1):92-93. doi: 10.4103/0974-2069.197057. No abstract available.

PMID: 28163440 Free PMC Article

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  1. Early primary graft failure after a pediatric heart transplant and successful rescue with plasmapheresis, immunoglobulins, and alemtuzumab.

Raj S, Ruiz P, Rusconi P.

Ann Pediatr Cardiol. 2017 Jan-Apr;10(1):69-71. doi: 10.4103/0974-2069.197063.

PMID: 28163432 Free PMC Article

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  1. Modified closed chamber sutureless technique for anomalous pulmonary venous connection.

Menon S, Mathew T, Karunakaran J, Dharan BS.

Ann Pediatr Cardiol. 2017 Jan-Apr;10(1):58-60. doi: 10.4103/0974-2069.197066.

PMID: 28163429 Free PMC Article

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  1. Elective nasal continuous positive airway pressure to support respiration after prolonged ventilation in infants after congenital cardiac surgery.

Gandhi H, Mishra A, Thosani R, Acharya H, Shah R, Surti J, Sarvaia A.

Ann Pediatr Cardiol. 2017 Jan-Apr;10(1):26-30. doi: 10.4103/0974-2069.197055.

PMID: 28163425 Free PMC Article

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