CHD Surgery Featured Articles of May 2016

  1. Evaluation of Explanted CorMatrix Intracardiac Patches in Children With Congenital Heart Disease.

Nelson JS, Heider A, Si MS, Ohye RG.

Ann Thorac Surg. 2016 May 26. pii: S0003-4975(16)30221-1. doi: 10.1016/j.athoracsur.2016.03.086. [Epub ahead of print]

PMID: 27237540

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Select item 27225489

Take Home Points

  1. CorMatrix, a biological scaffold, has been used in various congenital heart surgeries with a hope that cardiac cell grows into the CorMatrix patch.
  2. When used in CorMatrix in a hemi-Fontan baffle, there was no evidence of cardiac cell ingrowth on the CorMatrix patches at the median of 21 months after implantation
  3. Contrary to the hypothesis, CorMatrix failed to be a biological scaffold with a capacity to accommodate cardiac cell growth in.

Dr. Honjo 9-2015-2Commentary from Dr. Osami Honjo (Toronto), section editor of Congenital Heart Surgery Journal Watch:  CorMatrix is a biological scaffold based derived from porcine small intestinal submucosa extracellular matrix. Some animal studies showed that CorMatrix patches remodels into myocardial tissues. However, recent many clinical series showed mixed and somewhat negative results. Dr. Nelson and colleagues from Michigan demonstrated pathological outcome of implanted CorMatrix patch in pediatric patients. The study focused on a question whether there is any cardiac cell ingrowth on the CorMatrix patches. The answer was no. Among 10 specimens that were used as a hemi-Fontan baffle, there was no evidence of ingrowth of native cells or transformation into cardiac tissue at a median of 21 months after implantation. In the conference discussion, Dr. John Mayer commented that this is not surprising since this patch is a non-living tissue.

cts1
The figure showed acellular CorMatrix and associated fibrosis on Trichrome stain.

We at HSC Toronto and other groups have used CorMatrix patches for various reconstructions in congenital heart surgery, but it has been largely abandoned due to some problems in a high-pressure system and uncertainty of cell ingrowth. Since we are dealing with ‘growing’ children who need intracardiac reconstruction, we are eager to have a biological patch with a growth potential. Nonetheless this patch may not be the one.

 

  1. Cognitive Dysfunction in Children with Heart Disease: The Role of Anesthesia and Sedation.

Char D, Ramamoorthy C, Wise-Faberowski L.

Congenit Heart Dis. 2016 May 26. doi: 10.1111/chd.12352. [Epub ahead of print] Review.

PMID: 27228360

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Select item 27226033

Take Home Points:

  1. Commonly used anesthetic argents in children are known to have potential neurotoxicity, which actions are mainly through GABA and NMDA receptors.
  2. Small age at anesthetic exposure, and multiple anesthesia exposures are found to be predictors for late neurological consequences, such as attension deficit hyperactivity disorder.
  3. Dexmedetomidine, alpha2-adrenoceptor agonist, can be potentially less harmful or neuroprotective, and therefore further studies are warranted.

Commentary from Dr. Osami Honjo (Toronto), section editor of Congenital Heart Surgery Journal Watch:  This is an excellent review article written by Dr. Char and colleagues from the Stanford anesthesia group regarding the association between anesthesia/sedation and cognitive dysfunction in children with heart disease. The article summarized existing animal and clinical data, and gave some suggestions. In the study reported by Kalkman et al showed more behavioral disturbances in children who were anesthetized for urological procedures when they are under 2 years old. The report from Mayo Clinic, which is one of the best clinical studies in this subject, investigated 5357 children from birth. Among children who were exposed to anesthesia less than 2 years of age, children who received only 1 anesthetic exposure had no tangible risk, although children who had multiple anesthetic exposure had a 1.95 times greater risk for attention deficit hyperactivity disorder. The authors mentioned that dexmedetomidine, an alpha2-adrenoceptor agonist, can be a safer drug option, since developmental anesthetic neurotoxicity has largely been associated with the combination of GABAergic and NMDA antagonists’ actions of anesthetic drugs. There are some prospective studies under way to examine effects of dexmedetomidine.

 

  1. Medium-term outcomes after pulmonary valve replacement with the Freestyle valve for congenital heart disease: a case series.

Dunne B, Suthers E, Xiao P, Xiao J, Litton E, Andrews D.

Eur J Cardiothorac Surg. 2016 May;49(5):e105-11. doi: 10.1093/ejcts/ezw024. Epub 2016 Feb 22.

PMID: 26905179

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Select item 26738930

Take Home Points:

  1. The Freestyle valve is a stentless bioprosthetic valve from the porcine aortic root, which is decellularized with glutaraldehyde and treated with alpha-amino oleic acid to minimize xenograft calcification.
  2. Among 114 patients with heterogeneous diagnoses who received a freestyle valve, freedom from structural valve dysfunction SVD at 10 years was 61% and intervention-free survival at 10 years was 71%.
  3. A freestyle valve has comparable durability and longevity compared to homografts.

Commentary from Dr. Osami Honjo (Toronto), section editor of Congenital Heart Surgery Journal Watch:  Dr. Dunne and colleagues from Perth, Australia investigated 114 patients with congenital heart diseases who underwent pulmonary valve replacement (PVR) with a freestyle bioprosthetic valve. The freestyle valve is a stentless bioprosthetic valve from the porcine aortic root. It is decellularized with glutaraldehyde and treated with alpha-amino oleic acid to minimize xenograft calcification. The freestyle valve can be used in the pulmonary valve position as an alternative to a homograft or a tissue pulmonary valve. The study consisted of 114 congenital patients ranging from 11 to 35 years of age with a median age of 21 years. Approximately half of the cohort is tetralogy patients and about a 25% of the patients had a right ventricle-to-pulmonary artery (RV-PA) conduit at the time of initial corrective repair. Freedom from structural valve dysfunction (SVD) at 10 years was 61% and intervention-free survival at 10 years was 71%.

cts2
Figure: Intervention-free survival among patients who received a freestyle biosynthesis in the pulmonary valve position.

This report also has excellent summaries of durability comparison among homografts and various types of tissue valves. The authors concluded that the freestyle bioprosthetic valve performs equally well to the homografts and also suggested that it can be a valid alternative to stented bioprosthesis. I agree with the first conclusion that this can be a good alternative to homograft for RV-PA conduit replacement, given the worldwide shortage of homograft supply. I am not in total agreement with the second conclusion. For patients who have a native right ventricular outflow tract, i.e., tetralogy, pulmonary stenosis, etc., a standard stented tissue valve has been shown to have excellent long-term valve function and durability. It is also a much simpler operation. I would reserve this strategy for the patients who need entire RV-PA conduit replacement.

 

  1. Neurodevelopmental outcome in hypoplastic left heart syndrome: Impact of perioperative cerebral tissue oxygenation of the Norwood procedure.

Hansen JH, Rotermann I, Logoteta J, Jung O, Dütschke P, Scheewe J, Kramer HH.

J Thorac Cardiovasc Surg. 2016 May;151(5):1358-66. doi: 10.1016/j.jtcvs.2016.02.035. Epub 2016 Feb 24.

PMID: 27085616

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Select item 26783698

Take Home Points:

  1. This study investigated predictors for poor neurodevelopmental outcome in infants with hypoplastic left heart syndrome.
  2. Preoperative cerebral tissue oxygen saturation (ScO2) was lower in patients with below-average cognitive function tests.
  3. Gestational age, head circumference z-score, age at surgery, and postoperative length of stay were associated with IQ and cognitive function score (KET-KID).

Commentary from Dr. Osami Honjo (Toronto), section editor of Congenital Heart Surgery Journal Watch:  Dr. Hansen and colleagues from Germany reported a well-designed study investigating predictors for poor neurodevelopmental outcome in infants with hypoplastic left heart syndrome, with special focus on perioperative cerebral tissue oxygenation. The study included 43 children from 3.5 to 7 years of age who previously underwent Norwood procedure and subsequent staged single ventricle palliation. The study showed that IQ scores and cognitive functions are in the lower-normal range, and 63% of the patients have some degree of developmental delay in at least 1 neuropsychological domain. The authors found that preoperative cerebral tissue oxygen saturation (ScO2) was lower in patients with below-average cognitive function tests. Gestational age, head circumference z-score, age at surgery, and postoperative length of stay were associated with IQ and cognitive function score (KET-KID).

There is no question that infants with hypoplastic left heart syndrome are at a great risk of brain injury in the first 6 months of life, from abnormal fetal and preoperative physiology and cerebral perfusion, intraoperative circulatory arrest and inflammatory response, to postoperative hemodynamic instability. I am sure preoperative ScO2 can be one of the main potential sources of brain injury but there are many potential causes of cerebral low perfusion and subsequent brain injury. I am bit surprised to see that postoperative ScO2 was not found to be the predictor, since patients with low output state following Norwood procedure tend to have very low ScO2. Nonetheless this is one of the most important fields of further research and the authors should be congratulated with this excellent research article.

 

  1. Outcomes of children implanted with ventricular assist devices in the United States: First analysis of the Pediatric Interagency Registry for Mechanical Circulatory Support (PediMACS).

Blume ED, Rosenthal DN, Rossano JW, Baldwin JT, Eghtesady P, Morales DL, Cantor RS, Conway J, Lorts A, Almond CS, Naftel DC, Kirklin JK; PediMACS Investigators.

J Heart Lung Transplant. 2016 May;35(5):578-84. doi: 10.1016/j.healun.2016.01.1227. Epub 2016 Feb 10.

PMID: 27009673

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Select item 27009672

Take Home Points:

  1. PediMACS, The Pediatric Interagency Registry for Mechanical Circulatory Support, in the largest registry of pediatric mechanical circulatory support.
  2. This is the first report from this registry consisting of 200 patients who underwent durable ventricular assist device (VAD) implantation
  3. 86% of the patients had favorable outcome (58% transplanted, 28% on device alive) at 6 months.
  4. Adverse rates remains high even in this contemporary cohort.

cts3cts4

Commentary from Dr. Osami Honjo (Toronto), section editor of Congenital Heart Surgery Journal Watch:  Dr. Blume and investigators published the first dataset after initiation of the registry. The Pediatric Interagency Registry for Mechanical Circulatory Support (PediMACS) is a National Heart, Lung, and Blood institute-supported nationwide registry for ventricular assist device (VAD) used in patients <19 years of age. The series of publications in the May issue of the Journal of Heart and Lung Transplantation are very important data to show contemporary outcome of children who were supported by a VAD. 200 patients who received primary durable VAD had an actuarial survival of 81% at 6 months. Competing risk analysis at 6 months showed 86% of the patients have favorable outcome: 58% transplanted, 28% on device alive. There were 502 adverse events, including bleeding, cardiac arrhythmia, and device malfunction, etc. Considering the heterogeneous patient population and the various devices used, this is considered a great outcome, although adverse events rate remains high in the contemporary cohort.

 

OTHER RECOMMENDED CHD SURGERY ARTICLES – MAY 2016

  1. Supporting pediatric patients with short-term continuous-flow devices.

Conway J, Al-Aklabi M, Granoski D, Islam S, Ryerson L, Anand V, Guerra G, Mackie AS, Rebeyka I, Buchholz H.

J Heart Lung Transplant. 2016 May;35(5):603-9. doi: 10.1016/j.healun.2016.01.1224. Epub 2016 Feb 8.

PMID: 27009672

 

  1. Health-related quality of life in children with surgery for CHD: a study from the Swedish National Registry for Congenital Heart Disease.

Svensson B, Idvall E, Nilsson F, Liuba P.

Cardiol Young. 2016 May 26:1-11. [Epub ahead of print]

PMID: 27225489

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Select item 27228360

 

  1. Adverse events in children implanted with ventricular assist devices in the United States: Data from the Pediatric Interagency Registry for Mechanical Circulatory Support (PediMACS).

Rosenthal DN, Almond CS, Jaquiss RD, Peyton CE, Auerbach SR, Morales DR, Epstein DJ, Cantor RS, Kormos RL, Naftel DC, Butts RJ, Ghanayem NS, Kirklin JK, Blume ED.

J Heart Lung Transplant. 2016 May;35(5):569-77. doi: 10.1016/j.healun.2016.03.005. Epub 2016 Mar 17.

PMID: 27197775

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Select item 27009673

 

CHD SURGERY ARTICLES – MAY 2016

  1. Evaluation of Explanted CorMatrix Intracardiac Patches in Children With Congenital Heart Disease.

Nelson JS, Heider A, Si MS, Ohye RG.

Ann Thorac Surg. 2016 May 26. pii: S0003-4975(16)30221-1. doi: 10.1016/j.athoracsur.2016.03.086. [Epub ahead of print]

PMID: 27237540

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Select item 27225489

 

  1. Health-related quality of life in children with surgery for CHD: a study from the Swedish National Registry for Congenital Heart Disease.

Svensson B, Idvall E, Nilsson F, Liuba P.

Cardiol Young. 2016 May 26:1-11. [Epub ahead of print]

PMID: 27225489

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Select item 27228360

 

  1. Cognitive Dysfunction in Children with Heart Disease: The Role of Anesthesia and Sedation.

Char D, Ramamoorthy C, Wise-Faberowski L.

Congenit Heart Dis. 2016 May 26. doi: 10.1111/chd.12352. [Epub ahead of print] Review.

PMID: 27228360

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Select item 27226033

 

  1. Incidence and Predictors for Postoperative Thrombotic Complications in Children With Surgical and Nonsurgical Heart Disease.

Faraoni D, Gardella KM, Odegard KC, Emani SM, DiNardo JA.

Ann Thorac Surg. 2016 May 24. pii: S0003-4975(16)30218-1. doi: 10.1016/j.athoracsur.2016.03.083. [Epub ahead of print]

PMID: 27234574

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Select item 27220370

 

  1. Fungal infections in children in the early postoperative period after cardiac surgery for congenital heart disease: a single-centre experience.

Jaworski R, Haponiuk I, Irga-Jaworska N, Chojnicki M, Steffens M, Paczkowski K, Zielinski J.

Interact Cardiovasc Thorac Surg. 2016 May 24. pii: ivw156. [Epub ahead of print]

PMID: 27222000 Free Article

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Select item 27233471

 

  1. A case of severe perioperative hypoxia in uncorrected tetralogy of fallot: Anesthetic management.

Athar M, Ali S, Ahmed SM, Mazahir R.

Rev Esp Anestesiol Reanim. 2016 May 24. pii: S0034-9356(16)30027-5. doi: 10.1016/j.redar.2016.04.002. [Epub ahead of print] English, Spanish.

PMID: 27233471

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Select item 27214563

 

  1. Development and Validation of an Agency for Healthcare Research and Quality Indicator for Mortality After Congenital Heart Surgery Harmonized With Risk Adjustment for Congenital Heart Surgery (RACHS-1) Methodology.

Jenkins KJ, Koch Kupiec J, Owens PL, Romano PS, Geppert JJ, Gauvreau K.

J Am Heart Assoc. 2016 May 20;5(5). pii: e003028. doi: 10.1161/JAHA.115.003028.

PMID: 27207997 Free Article

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Select item 27207967

 

  1. The Use of Hypothermic Circulatory Arrest During Heart Transplantation Does Not Worsen Posttransplant Survival.

Sorabella RA, Guglielmetti L, Bader A, Gomez A, Takeda K, Chai PJ, Takayama H, Bacha EA, Naka Y, George I.

Ann Thorac Surg. 2016 May 18. pii: S0003-4975(16)30167-9. doi: 10.1016/j.athoracsur.2016.03.058. [Epub ahead of print]

PMID: 27209609

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  1. Surgery for doubly committed ventricular septal defects.

Shamsuddin AM, Chen YC, Wong AR, Le TP, Anderson RH, Corno AF.

Interact Cardiovasc Thorac Surg. 2016 May 11. pii: ivw129. [Epub ahead of print]

PMID: 27170744 Free Article

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Select item 27167685

 

  1. The Perioperative Use of Dexmedetomidine in Pediatric Patients with Congenital Heart Disease: An Analysis from the Congenital Cardiac Anesthesia Society-Society of Thoracic Surgeons Congenital Heart Disease Database.

Schwartz LI, Twite M, Gulack B, Hill K, Kim S, Vener DF.

Anesth Analg. 2016 May 10. [Epub ahead of print]

PMID: 27167685

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Select item 27166384

 

  1. Extracorporeal life support can be a first-line treatment in children with acute fulminant myocarditis.

Jung SY, Shin HJ, Jung JW, Park HK, Shin YR, Park YH, Kim NK, Choi JY.

Interact Cardiovasc Thorac Surg. 2016 May 10. pii: ivw114. [Epub ahead of print]

PMID: 27165733 Free Article

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Select item 27085581

 

  1. OC18 – Neurodevelopmental outcomes following congenital heart surgery.

Syrgani E, Petsios K.

Nurs Child Young People. 2016 May 9;28(4):68. doi: 10.7748/ncyp.28.4.68.s49.

PMID: 27214433

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Select item 27214416

 

  1. OC01 – The effect of an Interactive Therapeutic Play Training Program on the anxiety levels of children having heart surgery and their mothers.

Coşantürk AE, Gözen D.

Nurs Child Young People. 2016 May 9;28(4):58.

PMID: 27214416

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Select item 27160101

 

  1. Reconstruction of a Previously Repaired Aortic Valve Destroyed by Infective Endocarditis: Case Report.

Chalela T, Hraska V.

World J Pediatr Congenit Heart Surg. 2016 May 9. pii: 2150135116636571. [Epub ahead of print]

PMID: 27162188

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Select item 27155534

 

  1. Streptobacillus moniliformis Endocarditis: An Unusual Case of Pulmonary Valve Erosion Resulting in Free Pulmonary Regurgitation and Aneurysm.

Ioffe V, Amir G, Zalzstein E, Krymko H, Levitas A.

World J Pediatr Congenit Heart Surg. 2016 May 6. pii: 2150135116637808. [Epub ahead of print]

PMID: 27154799

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Select item 27154795

 

  1. Survival of Three Neonates With Congenital Diaphragmatic Hernia and d-Transposition of the Great Arteries.

Blancha VL, Ratner V, Aspelund G, Chai P, Levasseur S, Krishnan U, Bacha E, Krishnamurthy G.

World J Pediatr Congenit Heart Surg. 2016 May 6. pii: 2150135116632509. [Epub ahead of print]

PMID: 27154795

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Select item 27154793

 

  1. Long-Term Survival and Freedom From Reoperation After Placement of a Pulmonary Xenograft Valved Conduit.

Alfieris GM, Swartz MF, Lehoux J, Bove EL.

Ann Thorac Surg. 2016 May 3. pii: S0003-4975(16)00229-0. doi: 10.1016/j.athoracsur.2016.02.045. [Epub ahead of print]

PMID: 27154149

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Select item 27142960

 

  1. Does Survival on the Heart Transplant Waiting List Depend on the Underlying Heart Disease?

Hsich EM, Rogers JG, McNamara DM, Taylor DO, Starling RC, Blackstone EH, Schold JD.

JACC Heart Fail. 2016 May 3. pii: S2213-1779(16)30077-4. doi: 10.1016/j.jchf.2016.03.010. [Epub ahead of print]

PMID: 27179836

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Select item 27138626

 

  1. Dexmedetomidine Pharmacology in Neonates and Infants After Open Heart Surgery.

Su F, Gastonguay MR, Nicolson SC, DiLiberto M, Ocampo-Pelland A, Zuppa AF.

Anesth Analg. 2016 May;122(5):1556-66. doi: 10.1213/ANE.0000000000000869.

PMID: 26218862

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Select item 27212864

 

  1. Color Doppler and pulse wave assessment of flow in anomalous origin of left coronary artery from pulmonary artery: Pre- and post-surgery.

Bhalgat PS, Naik AV, Salvi PR, Joshi SV.

Ann Pediatr Cardiol. 2016 May-Aug;9(2):192-4. doi: 10.4103/0974-2069.180675.

PMID: 27212862 Free PMC Article

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Select item 27212859

 

  1. Scimitar syndrome: Surgical approach to an unusual anatomy of the scimitar vein.

Varghese R, Omoregbee B, Saheed S.

Ann Pediatr Cardiol. 2016 May-Aug;9(2):173-5. doi: 10.4103/0974-2069.180667.

PMID: 27212856 Free PMC Article

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Select item 27212854

 

  1. Complex aortopulmonary window in a single ventricle setting: Technical considerations for staged palliation.

Salve GG, Jain SA, Katkade SS, Shivaprakash K.

Ann Pediatr Cardiol. 2016 May-Aug;9(2):167-9. doi: 10.4103/0974-2069.180673.

PMID: 27212854 Free PMC Article

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Select item 27212845

 

  1. Non-Fontan Adult Congenital Heart Disease Transplantation Survival Is Equivalent to Acquired Heart Disease Transplantation Survival.

Besik J, Szarszoi O, Hegarova M, Konarik M, Smetana M, Netuka I, Pirk J, Maly J.

Ann Thorac Surg. 2016 May;101(5):1768-73. doi: 10.1016/j.athoracsur.2015.10.088. Epub 2016 Feb 6.

PMID: 26857637

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Select item 27020512

 

  1. Hypothermia During Cardiopulmonary Bypass Increases Need for Inotropic Support but Does Not Impact Inflammation in Children Undergoing Surgical Ventricular Septal Defect Closure.

Schmitt KR, Fedarava K, Justus G, Redlin M, Böttcher W, Delmo Walter EM, Hetzer R, Berger F, Miera O.

Artif Organs. 2016 May;40(5):470-9. doi: 10.1111/aor.12587. Epub 2015 Nov 19.

PMID: 26581834

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Select item 26496001

 

  1. Use of Ventricular Assist Device in Univentricular Physiology: The Role of Lumped Parameter Models.

Di Molfetta A, Ferrari G, Filippelli S, Fresiello L, Iacobelli R, Gagliardi MG, Amodeo A.

Artif Organs. 2016 May;40(5):444-53. doi: 10.1111/aor.12583. Epub 2015 Oct 23.

PMID: 26494529

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Select item 27002100

 

  1. Genetic polymorphism in postoperative sepsis after open heart surgery in infants.

Fakhri D, Djauzi S, Murni TW, Rachmat J, Harahap AR, Rahayuningsih SE, Mansyur M, Santoso A.

Asian Cardiovasc Thorac Ann. 2016 May;24(4):326-31. doi: 10.1177/0218492316640128. Epub 2016 Mar 21.

PMID: 27002100

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Select item 27108834

 

  1. Activation of the lectin pathway of complement by cardiopulmonary bypass contributes to the development of systemic inflammatory response syndrome after paediatric cardiac surgery.

Pągowska-Klimek I, Świerzko AS, Michalski M, Głowacka E, Szala-Poździej A, Sokołowska A, Moll M, Krajewski WR, Romak J, Cedzyński M.

Clin Exp Immunol. 2016 May;184(2):257-63. doi: 10.1111/cei.12763. Epub 2016 Feb 8.

PMID: 26703090

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Select item 27148590

 

  1. Right and left ventricular assist devices support and liver dysfunction: prognostic and therapeutic implications.

Maltais S, Stulak JM.

Curr Opin Cardiol. 2016 May;31(3):287-91. doi: 10.1097/HCO.0000000000000288.

PMID: 27008370

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Select item 26872209

 

  1. Parental perception of functional status and impact on the family of children with congenital heart surgery.

Garcia RU, Aggarwal S, Natarajan G.

Early Hum Dev. 2016 May;96:45-51. doi: 10.1016/j.earlhumdev.2016.03.004. Epub 2016 Mar 31.

PMID: 27037482

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Select item 27132629

 

 

  1. Down-sizing of cryopreserved homografts is a valuable technique, but do not make them too small.

Koolbergen DR.

Eur J Cardiothorac Surg. 2016 May;49(5):1426-7. doi: 10.1093/ejcts/ezv440. Epub 2016 Jan 5. No abstract available.

PMID: 26738930

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Select item 26613670

 

  1. Durability of down-sized homografts for the reconstruction of the right ventricular outflow tract.

Cleuziou J, Vitanova K, Kasnar-Samprec J, Hörer J, Lange R, Schreiber C.

Eur J Cardiothorac Surg. 2016 May;49(5):1421-5. doi: 10.1093/ejcts/ezv418. Epub 2015 Nov 27.

PMID: 26613670

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Select item 26574496

 

  1. Preoperative Sildenafil administration in children undergoing cardiac surgery: a randomized controlled preconditioning study.

Walavalkar V, Evers E, Pujar S, Viralam K, Maiya S, Frerich S, John C, Rao S, Reddy C, Spronck B, Prinzen FW, Delhaas T, Vanagt WY.

Eur J Cardiothorac Surg. 2016 May;49(5):1403-10. doi: 10.1093/ejcts/ezv353. Epub 2015 Oct 13.

PMID: 26464453

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Select item 27006109

 

  1. Mechanical circulatory support in pediatrics.

Steffen RJ, Miletic KG, Schraufnagel DP, Vargo PR, Fukamachi K, Stewart RD, Moazami N.

Expert Rev Med Devices. 2016 May;13(5):507-14. doi: 10.1586/17434440.2016.1162710. Epub 2016 Mar 21.

PMID: 26950799

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Select item 26884082

 

  1. Immediate and mid-term result of restrictive mitral annuloplasty using a small semi-rigid ring.

Umesue M, Baba H, Kimura S.

Gen Thorac Cardiovasc Surg. 2016 May;64(5):260-6. doi: 10.1007/s11748-016-0631-6. Epub 2016 Feb 16.

PMID: 26884082

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Select item 27061818

 

  1. Successful Bridge to Orthotopic Cardiac Transplantation with Implantation of a HeartWare HVAD in Management of Systemic Right Ventricular Failure in a Patient with Transposition of the Great Arteries and Previous Atrial Switch Procedure.

Stokes MB, Saxena P, McGiffin DC, Marasco S, Leet AS, Bergin P.

Heart Lung Circ. 2016 May;25(5):e69-71. doi: 10.1016/j.hlc.2015.11.006. Epub 2015 Dec 2.

PMID: 26712611

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Select item 26643289

 

  1. Long-term outcomes of the arterial switch operation for transposition of the great arteries and ventricular septal defect and/or aortic arch obstruction.

Baruteau AE, Vergnat M, Kalfa D, Delpey JG, Ly M, Capderou A, Lambert V, Belli E.

Interact Cardiovasc Thorac Surg. 2016 May 1. pii: ivw102. [Epub ahead of print]

PMID: 27141085 Free Article

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Select item 26848189

 

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Select item 26996929

  1. Outcome, incidence and risk factors for stroke after pediatric heart transplantation: An analysis of the International Society for Heart and Lung Transplantation Registry.

Morgan CT, Manlhiot C, McCrindle BW, Dipchand AI.

J Heart Lung Transplant. 2016 May;35(5):597-602. doi: 10.1016/j.healun.2016.01.1226. Epub 2016 Feb 9.

PMID: 26996929

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Select item 26922273

 

  1. A multicenter study of the HeartWare ventricular assist device in small children.

Miera O, Kirk R, Buchholz H, Schmitt KR, VanderPluym C, Rebeyka IM, Wrightson N, Berger F, Griselli M, Conway J.

J Heart Lung Transplant. 2016 May;35(5):679-81. doi: 10.1016/j.healun.2016.01.019. Epub 2016 Jan 18. No abstract available.

PMID: 26922273

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Select item 26880324

 

  1. Postcorrective surgery improvement of nocturnal hypoxemia in a case of partial anomalous pulmonary venous connection and aberrant hepatic vein drainage.

Agrawal A, Palkar AV, Sahni S, Vatsia SK, Shah RD, Talwar A.

Lung India. 2016 May-Jun;33(3):306-9. doi: 10.4103/0970-2113.180871.

PMID: 27185995 Free PMC Article

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Select item 26256673

 

  1. Parental perceptions of transition from intensive care following a child’s cardiac surgery.

Obas KA, Leal JM, Zegray M, Rennick JE.

Nurs Crit Care. 2016 May;21(3):e1-9. doi: 10.1111/nicc.12202. Epub 2015 Aug 10.

PMID: 26256673

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Select item 27177788

 

  1. [Surgical management of congenital heart defects beyond the age of 60].

Hartyánszky I, Varga S, Csepregi L, Babik B, Simon J, Havasi K, Kalapos A, Bogáts G.

Orv Hetil. 2016 May;157(21):820-4. doi: 10.1556/650.2016.30415. Hungarian.

PMID: 27177788

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Select item 26920816

 

  1. Double Root Switch Repair for Taussig-Bing Anomaly.

Furlanetto G, Furlanetto BH, Teixeira EM, Henriques S.

World J Pediatr Congenit Heart Surg. 2016 May;7(3):367-71. doi: 10.1177/2150135116644433.

PMID: 27142406

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  1. Tracheostomy Following Surgery for Congenital Heart Disease: A 14-year Institutional Experience.

Benneyworth BD, Shao JM, Cristea AI, Ackerman V, Rodefeld MD, Turrentine MW, Brown JW.

World J Pediatr Congenit Heart Surg. 2016 May;7(3):360-6. doi: 10.1177/2150135116644432.

PMID: 27142405

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  1. Surgical Repair of 115 Patients With Anomalous Aortic Origin of a Coronary Artery From a Single Institution.

Mainwaring RD, Murphy DJ, Rogers IS, Chan FP, Petrossian E, Palmon M, Hanley FL.

World J Pediatr Congenit Heart Surg. 2016 May;7(3):353-9. doi: 10.1177/2150135116641892.

PMID: 27142404

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49, Three Dimensional Printing: Applications in Surgery for Congenital Heart Disease.

Hibino N.

World J Pediatr Congenit Heart Surg. 2016 May;7(3):351-2. doi: 10.1177/2150135116644886. Review. No abstract available.

PMID: 27142403

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  1. Clinical Application and Multidisciplinary Assessment of Three Dimensional Printing in Double Outlet Right Ventricle With Remote Ventricular Septal Defect.

Garekar S, Bharati A, Chokhandre M, Mali S, Trivedi B, Changela VP, Solanki N, Gaikwad S, Agarwal V.

World J Pediatr Congenit Heart Surg. 2016 May;7(3):344-50. doi: 10.1177/2150135116645604.

PMID: 27142402

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  1. Use of a Three Dimensional Printed Cardiac Model to Assess Suitability for Biventricular Repair.

Farooqi KM, Gonzalez-Lengua C, Shenoy R, Sanz J, Nguyen K.

World J Pediatr Congenit Heart Surg. 2016 May;7(3):414-6. doi: 10.1177/2150135115610285. Epub 2016 Mar 23.

PMID: 27009890

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  1. Off-Pump Double Coronary Bypass in a Case of Familial Hypercholesterolemia With Coarctation of the Aorta.

Kaya M, Erkanlı K, Kyaruzi M, Bakır İ.

World J Pediatr Congenit Heart Surg. 2016 May;7(3):400-3. doi: 10.1177/2150135115593130. Epub 2016 Jan 21.

PMID: 26795904

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  1. Replacement of Regurgitant Bicuspid Aortic Valve in a Dilated, Non-Compacted Left Ventricle.

Schenone AL, Cohen A, Pettersson G, Majdalany D.

World J Pediatr Congenit Heart Surg. 2016 May;7(3):389-93. doi: 10.1177/2150135115592034. Epub 2015 Dec 23.

PMID: 26701622

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  1. Early clinical outcomes of right ventricular outflow tract reconstruction with small caliber bovine jugular vein conduit (Contegra®) in small children.

Kido T, Hoashi T, Kagisaki K, Fujiyoshi T, Kitano M, Kurosaki K, Shiraishi I, Yagihara T, Sawa Y, Ichikawa H.

J Artif Organs. 2016 May 28. [Epub ahead of print]

PMID: 27236437

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  1. Novel Modifications of a Ventricular Assist Device for Infants and Children.

Mongé MC, Kulat BT, Eltayeb O, Balasubramanya S, Sarwark AE, Zingle NR, Moss ST, Moga MA, Gossett JG, Pahl E, Costello JM, Backer CL.

Ann Thorac Surg. 2016 May 27. pii: S0003-4975(16)30373-3. doi: 10.1016/j.athoracsur.2016.04.043. [Epub ahead of print]

PMID: 27240450

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  1. Health-related quality of life in children with surgery for CHD: a study from the Swedish National Registry for Congenital Heart Disease.

Svensson B, Idvall E, Nilsson F, Liuba P.

Cardiol Young. 2016 May 26:1-11. [Epub ahead of print]

PMID: 27225489

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  1. Surgical correction of a coronary fistula between the left main coronary artery and the coronary sinus in a neonate.

Taverne YJ, de Jong PL, Witsenburg M, Bogers AJ.

Interact Cardiovasc Thorac Surg. 2016 May 26. pii: ivw163. [Epub ahead of print]

PMID: 27230538 Free Article

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  1. Rituximab Therapy for Rejection in Pediatric Heart Transplant.

Erdogan I, Varan B, Sezgin A, Pirat A, Zeyneloglu P.

Exp Clin Transplant. 2016 May 17. doi: 10.6002/ect.2015.0370. [Epub ahead of print]

PMID: 27210774

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  1. Risk factors and outcomes of in-hospital cardiac arrest following pediatric heart operations of varying complexity.

Gupta P, Rettiganti M, Jeffries HE, Scanlon MC, Ghanayem NS, Daufeldt J, Rice TB, Wetzel RC.

Resuscitation. 2016 May 13;105:1-7. doi: 10.1016/j.resuscitation.2016.04.022. [Epub ahead of print]

PMID: 27185218

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  1. Pediatric extracorporeal life support using a third generation diagonal pump.

Speth M, Münch F, Purbojo A, Glöckler M, Toka O, Cesnjevar RA, Rüffer A.

ASAIO J. 2016 May 9. [Epub ahead of print]

PMID: 27164039

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  1. Extended Septal Myectomy for Hypertrophic Obstructive Cardiomyopathy in Children and Adolescents.

Xu H, Yan J, Wang Q, Li D, Guo H, Li S, Wang J, Lou S, Zeng Q.

Pediatr Cardiol. 2016 May 9. [Epub ahead of print]

PMID: 27160105

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  1. Impact and Challenges of a Policy Change to Early Track Extubation in the Operating Room for Fontan.

Kawaguchi A, Liu Q, Coquet S, Yasui Y, Cave D.

Pediatr Cardiol. 2016 May 9. [Epub ahead of print]

PMID: 27160099

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  1. Intermediate-Term Results After Extracardiac Conduit Fontan Palliation in Children and Young Adults with Single Ventricle Physiology-A Single-center Experience.

Raj S, Rosenkranz E, Sears B, Swaminathan S.

Pediatr Cardiol. 2016 May 9. [Epub ahead of print]

PMID: 27160098

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  1. Ventricular Septal Defect Creation: A Viable Option to Decompress a Large Nonsystemic Left Ventricle in a Fontan Patient.

Elderie A, Reddy A, Zafar F, Hirsch R, Morales DL.

World J Pediatr Congenit Heart Surg. 2016 May 6. pii: 2150135116634291. [Epub ahead of print]

PMID: 27154798

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  1. Successful Surgical Excision of a Large Cardiac Fibroma in an Asymptomatic Child: A Case Report.

Borodinova O, Ostras O, Raad T, Yemets I.

World J Pediatr Congenit Heart Surg. 2016 May 3. pii: 2150135116634287. [Epub ahead of print]

PMID: 27143716

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  1. Challenging the convention of size matching by weight in pediatric heart transplantation.

Flyer JN, Zuckerman WA.

Pediatr Transplant. 2016 May 2. doi: 10.1111/petr.12717. [Epub ahead of print] No abstract available.

PMID: 27136329

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Select item 26976792

 

  1. Usefulness of Diastolic Strain Measurements in Predicting Elevated Left Ventricular Filling Pressure and Risk of Rejection or Coronary Artery Vasculopathy in Pediatric Heart Transplant Recipients.

Lu JC, Magdo HS, Yu S, Lowery R, Aiyagari R, Zamberlan M, Gajarski RJ.

Am J Cardiol. 2016 May 1;117(9):1533-8. doi: 10.1016/j.amjcard.2016.02.009. Epub 2016 Feb 17.

PMID: 26976792

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  1. Intraoperative Transesophageal Echocardiography in the Norwood-Sano Palliation of Hypoplastic Left Heart Syndrome.

Bianchi DA, Balbella A, Motta P.

Anesth Analg. 2016 May;122(5):1301-4. doi: 10.1213/ANE.0000000000001139. No abstract available.

PMID: 27101490

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  1. Procalcitonin as a biomarker of bacterial infection in pediatric patients after congenital heart surgery.

Chakravarti SB, Reformina DA, Lee TM, Malhotra SP, Mosca RS, Bhatla P.

Ann Pediatr Cardiol. 2016 May-Aug;9(2):115-9. doi: 10.4103/0974-2069.180665.

PMID: 27212844 Free PMC Article

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  1. Application of Cone Reconstruction for Neonatal Ebstein Anomaly or Tricuspid Valve Dysplasia.

Mizuno M, Hoashi T, Sakaguchi H, Kagisaki K, Kitano M, Kurosaki K, Yoshimatsu J, Shiraishi I, Ichikawa H.

Ann Thorac Surg. 2016 May;101(5):1811-7. doi: 10.1016/j.athoracsur.2015.11.029. Epub 2016 Feb 23.

PMID: 26916715

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  1. Reoperation for right ventricular outflow tract obstruction after arterial switch operation for transposition of the great arteries and aortic arch obstruction.

Bokenkamp R, Aguilar E, van der Palen RL, Sojak V, Bruggemans EF, Hruda J, Kuipers IM, Hazekamp MG.

Eur J Cardiothorac Surg. 2016 May;49(5):e91-6. doi: 10.1093/ejcts/ezw026.

PMID: 27130951

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  1. Lipoblastoma: an unusual tumour of the left ventricle.

Sharma P, Shakya U, Sayami G, Rajbanshi BG.

Eur J Cardiothorac Surg. 2016 May;49(5):e147-8. doi: 10.1093/ejcts/ezv490. Epub 2016 Jan 27.

PMID: 26819289

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  1. Long-term outcome after treatment of pulmonary atresia with ventricular septal defect: nationwide study of 109 patients born in 1970-2007.

Kaskinen AK, Happonen JM, Mattila IP, Pitkänen OM.

Eur J Cardiothorac Surg. 2016 May;49(5):1411-8. doi: 10.1093/ejcts/ezv404. Epub 2015 Nov 29.

PMID: 26620210

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  1. Surgical Treatment of Congenital Mitral Valve Dysplasia.

Vida VL, Carrozzini M, Padalino M, Milanesi O, Stellin G.

J Card Surg. 2016 May;31(5):352-6. doi: 10.1111/jocs.12743. Epub 2016 Apr 12.

PMID: 27072822

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  1. Induced Pectus Carinatum.

Maddali MM, Valliattu J, Kandachar PS, Thomas E, Nishant AR.

J Card Surg. 2016 May;31(5):357-60. doi: 10.1111/jocs.12734. Epub 2016 Mar 16.

PMID: 26989996

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  1. Compassionate deactivation of ventricular assist devices in pediatric patients.

Hollander SA, Axelrod DM, Bernstein D, Cohen HJ, Sourkes B, Reddy S, Magnus D, Rosenthal DN, Kaufman BD.

J Heart Lung Transplant. 2016 May;35(5):564-7. doi: 10.1016/j.healun.2016.03.020. Epub 2016 Mar 31.

PMID: 27197773

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Select item 27056613

 

  1. Outpatient management of a child with bidirectional Glenn shunts supported with implantable continuous-flow ventricular assist device.

Adachi I, Jeewa A, Burki S, McKenzie ED, Fraser CD Jr.

J Heart Lung Transplant. 2016 May;35(5):688-90. doi: 10.1016/j.healun.2016.01.1218. Epub 2016 Feb 9. No abstract available.

PMID: 27056613

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  1. Outcomes of pediatric patients supported with continuous-flow ventricular assist devices: A report from the Pediatric Interagency Registry for Mechanical Circulatory Support (PediMACS).

Rossano JW, Lorts A, VanderPluym CJ, Jeewa A, Guleserian KJ, Bleiweis MS, Reinhartz O, Blume ED, Rosenthal DN, Naftel DC, Cantor RS, Kirklin JK.

J Heart Lung Transplant. 2016 May;35(5):585-90. doi: 10.1016/j.healun.2016.01.1228. Epub 2016 Feb 10.

PMID: 27056612

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  1. Supporting pediatric patients with short-term continuous-flow devices.

Conway J, Al-Aklabi M, Granoski D, Islam S, Ryerson L, Anand V, Guerra G, Mackie AS, Rebeyka I, Buchholz H.

J Heart Lung Transplant. 2016 May;35(5):603-9. doi: 10.1016/j.healun.2016.01.1224. Epub 2016 Feb 8.

PMID: 27009672

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  1. The concept of “palliation” in children with heterotaxy syndrome.

Cheung EW, Bacha EA.

J Thorac Cardiovasc Surg. 2016 May;151(5):1378-9. doi: 10.1016/j.jtcvs.2016.02.050. Epub 2016 Feb 27. No abstract available.

PMID: 27085619

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  1. Fluid Overload After Neonatal Cardiac Surgery Is Bad: Keep the Bottles on the Shelf, Squeeze the Patients…or Both?

Ricci Z.

Pediatr Crit Care Med. 2016 May;17(5):463-5. doi: 10.1097/PCC.0000000000000720. No abstract available.

PMID: 27144694

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  1. Fluid Overload Is Associated With Late Poor Outcomes in Neonates Following Cardiac Surgery.

Wilder NS, Yu S, Donohue JE, Goldberg CS, Blatt NB.

Pediatr Crit Care Med. 2016 May;17(5):420-7. doi: 10.1097/PCC.0000000000000715.

PMID: 27028790

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  1. Risk Factors for Longer Hospital Stay Following the Fontan Operation.

Sasaki J, Dykes JC, Sosa LJ, Salvaggio JL, Tablante MD, Ojito J, Khan DM, Hannan RL, Rossi AF, Burke RP, Wernovsky G.

Pediatr Crit Care Med. 2016 May;17(5):411-9. doi: 10.1097/PCC.0000000000000701.

PMID: 26927939

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  1. End-stage ischemic heart failure and Williams-Beuren syndrome: A unique scenario for pediatric heart transplantation.

González-López MT, Pérez-Caballero-Martínez R, Granados-Ruiz MÁ, García-Torres E, Álvarez-García-Rovés R, Gil-Villanueva N, Camino-López M, Gil-Jaurena JM.

Pediatr Transplant. 2016 May;20(3):472-476. doi: 10.1111/petr.12694. Epub 2016 Feb 25.

PMID: 26918834

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  1. Chronic kidney disease after heart transplantation: a single-centre retrospective study at Skåne University Hospital in Lund 1988-2010.

Söderlund C, Löfdahl E, Nilsson J, Reitan Ö, Higgins T, Rådegran G.

Transpl Int. 2016 May;29(5):529-39. doi: 10.1111/tri.12710.

PMID: 26531026

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  1. Hybrid Stage 1 Palliation in a Patient With Hypoplastic Left Heart Syndrome and Unusual Decompressing Levoatrial Cardinal Vein in Turner Syndrome: Utility of Multimodality Imaging.

Kaliki Venkata G, Fudge JC, Vyas HV, Bleiweis MS, Chandran A.

World J Pediatr Congenit Heart Surg. 2016 May;7(3):375-6. doi: 10.1177/2150135116641908. No abstract available.

PMID: 27142408

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  1. Mitral Valve Surgery for Rheumatic Lesions in Young Patients.

Cardoso B, Loureiro P, Gomes I, Gordo A, Banazol N, Fragata I, Trigo C, Pinto F, Fragata J.

World J Pediatr Congenit Heart Surg. 2016 May;7(3):321-8. doi: 10.1177/2150135116637806.

PMID: 27142399

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  1. A Tubular Aortopulmonary Window: An Embryological Curiosity.

Chidambarathanu S, Agarwal R, Hussain ZM, Brown NA, Anderson RH.

World J Pediatr Congenit Heart Surg. 2016 May;7(3):411-3. doi: 10.1177/2150135115596586. Epub 2016 Jan 21.

PMID: 26795903

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