Congenital EP Featured Articles of May 2016

  1. Arrhythmogenic anatomical isthmuses identified by electroanatomical mapping are the substrate for ventricular tachycardia in repaired tetralogy of Fallot.

Kapel GF, Sacher F, Dekkers OM, Watanabe M, Blom NA, Thambo JB, Derval N, Schalij MJ, Jalal Z, Wijnmaalen AP, Zeppenfeld K.

Eur Heart J. 2016 May 26. pii: ehw202. [Epub ahead of print]

PMID: 27233946

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Select item 27229665

Take Home Points:

  1. Patients with repaired tetralogy of Fallot (TOF) have well-defined anatomical isthmuses that support reentrant monomorphic ventricular tachycardia (VT).
  1. The electrical properties of these anatomical isthmuses can be characterized at invasive electrophysiology study.
  1. Patients with inducible VT have anatomical isthmuses that are more abnormal in terms of longer and narrower dimensions, and conduct more slowly than those without inducible VT.
  1. Slower conduction velocity appears to be the most predictive factor for inducible VT after surgical repair of TOF.

J MooreCommentary from Dr. Jeremy Moore (Los Angeles), section co-editor of Pediatric EP Journal Watch:  Patients with surgically repaired tetralogy of Fallot (TOF) are at increased risk for sustained monomorphic ventricular tachycardia (VT) during long-term follow-up. The Netherlands group reports new findings that may predict inducible or inducible and/or spontaneous VT by evaluating the electro-anatomical substrate for VT in this population.

Seventy-four patients with TOF underwent invasive electrophysiologic evaluation. Four previously described anatomical isthmuses (AI) were characterized in terms of length (distance between normal bipolar electrograms at each end), width, and conduction velocity (CVi) through the isthmus (calculated as meters/second). An AI was also characterized as electrically abnormal if associated with a voltage <1.5 mV throughout its length. The CVi from a group of 12 healthy controls undergoing PVC ablation were used for comparison (mean 1.24 ± 0.32 m/sec).

ep1

The AI was electrically abnormal in 26/28 repaired TOF patients with inducible VT whereas it was abnormal in only 5/46 patients without inducible VT. On average, patients with inducible VT also had AI lengths that were 8 mm narrower and 6 mm longer as compared to those without inducible VT. The most prominent difference in isthmus characteristics between patients with versus those without inducible VT was the CVi. For patients with inducible VT, the CVI was only 0.36 ± 0.34 whereas it was 0.78 ± 0.78 for those without inducible VT (p<0.001). There was no difference in isthmus length, width, or conduction velocity among patients with inducible VT versus those with spontaneous VT. Based on these findings, the authors suggested that a CVi <0.5 m/sec should be considered abnormal. The sensitivity and specificity of an SCAI with CVi <0.5 m/sec to predict AI-related VT was 93 and 100% respectively.

TOF patients were further grouped into the following: group A – discharged home without a slowly-conducting AI (SCAI) (n=62) and group B – discharged home with an SCAI (n=10). Over a mean follow up of 50 ± 22 months, all group A patients remained free of VT. Of group B patients, 5/10 experienced ≥1 episode of VT. The authors therefore suggested that repaired TOF patients without an arrhythmogenic isthmus in the setting of a normal biventricular function may not require ICD implantation.

 

  1. Incidence and characteristics of heart block after heart surgery in pediatric patients: A multicenter study.

Liberman L, Silver ES, Chai PJ, Anderson BR.

J Thorac Cardiovasc Surg. 2016 May 7. pii: S0022-5223(16)30104-0. doi: 10.1016/j.jtcvs.2016.03.081. [Epub ahead of print]

PMID: 27167020

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Select item 27150455

Take Home Points:

  1. In the current era, post-surgical AV block appears to be greatest after the double-switch operation and tricuspid and mitral valve replacement.
  1. Post-surgical AV block and pacemaker implantation is associated with in-hospital mortality even after controlling for center effect and patient comorbidities.

Commentary from Dr. Jeremy Moore (Los Angeles), section co-editor of Pediatric EP Journal Watch:  This group conducted a retrospective cohort study using the Pediatric Health Information System database (which contains data for 45 tertiary academic centers). Children undergoing intracardiac surgery for congenital heart disease who were ≤18 years were included. The primary search results were advanced second- or third-degree AV block, or patients with unspecified heart block who underwent pacemaker or implantable cardioverter-defibrillator placement.

A total of 74,571 patients at 42 hospitals between January 1, 2004 and December 31, 2013 were included in the data analysis. Nine-hundred ninety patients (1%) underwent cardiac device placement, with the highest risk after double-switch operation (16%), tricuspid valve surgery (8%), and mitral valve replacement (7%). See below for the complete breakdown of risk by congenital lesion.

ep2

Rates are graphically depicted for each procedure as a function of the number of cases. Lines depicting the 5th and 95th binomial prediction limits are superimposed to create a funnel plot. Procedure types falling above or below these limits are associated with significantly high or low incidences, respectively.

Center and surgeon volumes were not associated with risk of heart block and/or pacemaker placement. However, post-operative heart block and pacemaker implantation was associated with increased risk of in-hospital mortality (odds ratio 2.0; 95% CI 1.51-2.74, p<0.001) even after controlling for center effect, RACHS-1 category, and comorbidities (genetic abnormality and other chronic hematologic, renal, gastrointestinal, and neurologic conditions), age at surgery, and admission year. The mean hospital cost was increased for patients with heart block and pacemaker implantation ($120,377 versus $47,841; p<0.001).

The authors concluded that the risk of heart block was highest for children undergoing the double switch operation (15%) and tricuspid and mitral valve replacements (~7% for each) and that hospital mortality is associated with this complication, even after controlling for potential confounders.

 

  1. Catheter Ablation of Supraventricular Tachyarrhythmia after Extracardiac Fontan Surgery.

Moore JP, Shannon KM, Fish FA, Seslar SP, Garnreiter JM, Krause U, Tanel RE, Papez AA, Pilcher TA, Balaji S.

Heart Rhythm. 2016 May 25. pii: S1547-5271(16)30320-4. doi: 10.1016/j.hrthm.2016.05.019. [Epub ahead of print]

PMID: 27236028

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Select item 27225165

Take Home Points:

  1. Catheter ablation for patients after extracardiac total cavopulmonary connection (E-TCPC) surgery can be performed effectively.
  1. The trans-conduit approach appears to be a safe route for access to the pulmonary venous atrium.
  1. When the E-TCPC is the initial Fontan operation (i.e. no prior Fontan conversion surgery), the critical isthmus for IART appears to be most commonly bounded by the atrioventricular annulus anteriorly, and the oversewn IVC posteriorly.

Commentary from Dr. Jeremy Moore (Los Angeles), section co-editor of Pediatric EP Journal Watch:  This was a multicenter study from 9 tertiary academic centers performing catheter ablation for patients with complex congenital heart disease. The authors identified a total of 36 patients with either prior E-TCPC as a de novo operation (n=24) or as a result of Fontan conversion surgery (n=12). Although 21 patients had a fenestration created at the time of surgery, only 12 had a patent fenestration by the time of the catheter ablation procedure. Routes of access to the pulmonary venous atrium (PVA) included most commonly conduit puncture in 63%, fenestration in 26%, and retrograde in 13%.

The most common form of supraventricular tachycardia was IART 21 patients (58%) followed by focal AT in 7 (19%).  Patients after de novo E-TCPC were significantly more likely to have an IART circuit using an isthmus between the AV valve annulus anteriorly and the oversewn IVC posteriorly than those after Fontan conversion surgery (p=0.007). Other forms of paroxysmal SVT were commonly observed, and included AV reciprocating tachycardia mediated by either an accessory pathway or twin AV nodes and AV node reentry tachycardia. These other forms of supraventricular tachycardia were significantly associated with heterotaxy syndrome (p=0.02).

ep3

Overall, acute success was achieved in 83% after the final procedure with 8 complications noted (17%). Only 1 complication required intervention (epicardial pacemaker implantation after catheter ablation of twin AV node tachycardia). Overall recurrence was noted in 6 patients (17%) during a median follow up of 0.4 months and was more common after Fontan conversion (p=0.024).

The authors concluded that catheter ablation is an effective therapy for patients after E-TCPC and can be accomplished by transconduit puncture without significant morbidity. The techniques for transconduit puncture are extensively discussed.

 

OTHER RECOMMENDED CHD EP ARTICLES – MAY 2016

  1. Defibrillation Testing Strategies of Pediatric and Adult Congenital Electrophysiologists during ICD implantation.

Baysa SJ, Olen M, Kanter R, Fishberger SB.

Pacing Clin Electrophysiol. 2016 May 26. doi: 10.1111/pace.12896. [Epub ahead of print]

PMID: 27226114

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Select item 27228382

 

  1. Arrhythmic Burden and Ambulatory Monitoring of Pediatric Patients with Cardiomyopathy.

Czosek RJ, Jefferies JL, Khoury PR, Anderson JB, Wilmot I, Knilans TK, Spar DS.

Pacing Clin Electrophysiol. 2016 May;39(5):443-51. doi: 10.1111/pace.12835. Epub 2016 Mar 28.

PMID: 26935486

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Select item 26920816

 

  1. A Review of Surgical Atrioventricular Block with Emphasis in Patients with Single Ventricle Physiology.

Marshall AM.

Congenit Heart Dis. 2016 May 3. doi: 10.1111/chd.12372. [Epub ahead of print]

PMID: 27139742

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Select item 27179205

 

CHD EP ARTICLES – MAY 2016

  1. Left ventricular dysfunction is associated with frequent premature ventricular complexes and asymptomatic ventricular tachycardia in children.

Bertels RA, Harteveld LM, Filippini LH, Clur SA, Blom NA.

Europace. 2016 May 31. pii: euw075. [Epub ahead of print]

PMID: 27247014

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Select item 27247006

 

  1. Sudden cardiac death in adult congenital heart disease: can the unpredictable be foreseen?

Koyak Z, de Groot JR, Bouma BJ, Zwinderman AH, Silversides CK, Oechslin EN, Budts W, Van Gelder IC, Mulder BJ, Harris L.

Europace. 2016 May 31. pii: euw060. [Epub ahead of print]

PMID: 27247006

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Select item 27243624

 

  1. Improving Defibrillation Efficiency in Area Schools.

Thomas VC, Shen JJ, Stanley R, Dahlke J, McPartlin S, Row L.

Congenit Heart Dis. 2016 May 30. doi: 10.1111/chd.12375. [Epub ahead of print]

PMID: 27237434

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Select item 27232196

 

  1. Arrhythmogenic anatomical isthmuses identified by electroanatomical mapping are the substrate for ventricular tachycardia in repaired tetralogy of Fallot.

Kapel GF, Sacher F, Dekkers OM, Watanabe M, Blom NA, Thambo JB, Derval N, Schalij MJ, Jalal Z, Wijnmaalen AP, Zeppenfeld K.

Eur Heart J. 2016 May 26. pii: ehw202. [Epub ahead of print]

PMID: 27233946

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Select item 27229665

 

  1. Long-term follow-up of implantable cardioverter-defibrillators in adult congenital heart disease patients: indications and outcomes.

Santharam S, Hudsmith L, Thorne S, Clift P, Marshall H, De Bono J.

Europace. 2016 May 26. pii: euw076. [Epub ahead of print]

PMID: 27234868

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Select item 27230020

 

  1. Defibrillation Testing Strategies of Pediatric and Adult Congenital Electrophysiologists during ICD implantation.

Baysa SJ, Olen M, Kanter R, Fishberger SB.

Pacing Clin Electrophysiol. 2016 May 26. doi: 10.1111/pace.12896. [Epub ahead of print]

PMID: 27226114

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Select item 27228382

 

  1. Right Parasternal Lead Placement Increases Eligibility for Subcutaneous Implantable Cardioverter Defibrillator Therapy in Adults With Congenital Heart Disease.

Okamura H, McLeod CJ, DeSimone CV, Webster TL, Bonnichsen CR, Grogan M, Phillips SD, Connolly HM, Ammash NM, Warnes CA, Friedman PA.

Circ J. 2016 May 25;80(6):1328-35. doi: 10.1253/circj.CJ-16-0153. Epub 2016 Apr 22.

PMID: 27109124 Free Article

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Select item 27225805

 

  1. Catheter Ablation of Supraventricular Tachyarrhythmia after Extracardiac Fontan Surgery.

Moore JP, Shannon KM, Fish FA, Seslar SP, Garnreiter JM, Krause U, Tanel RE, Papez AA, Pilcher TA, Balaji S.

Heart Rhythm. 2016 May 25. pii: S1547-5271(16)30320-4. doi: 10.1016/j.hrthm.2016.05.019. [Epub ahead of print]

PMID: 27236028

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Select item 27225165

 

  1. Cardiac resynchronization therapy in congenital heartdisease.

Janoušek J, Kubuš P.

Herzschrittmacherther Elektrophysiol. 2016 May 25. [Epub ahead of print]

PMID: 27225165

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Select item 27225164

 

  1. Surgical aspects of atrial arrhythmia : Right atrial ablation and anti-arrhythmic surgery in congenital heart disease.

Uemura H.

Herzschrittmacherther Elektrophysiol. 2016 May 25. [Epub ahead of print]

PMID: 27225164

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Select item 27236281

 

  1. Molecular and Functional Characterization of Rare CACNA1C Variants in Sudden Unexplained Death in the Young.

Sutphin BS, Boczek NJ, Barajas-Martínez H, Hu D, Ye D, Tester DJ, Antzelevitch C, Ackerman MJ.

Congenit Heart Dis. 2016 May 24. doi: 10.1111/chd.12371. [Epub ahead of print]

PMID: 27218670

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  1. [Antibradycardia therapy : Indication and implementation].

Zartner P.

Herzschrittmacherther Elektrophysiol. 2016 May 24. [Epub ahead of print] German.

PMID: 27221084

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Select item 27221083

 

  1. [Arrhythmia in adults with congenital heart disease : Acute and long-term management].

Hessling G.

Herzschrittmacherther Elektrophysiol. 2016 May 24. [Epub ahead of print] German.

PMID: 27221083

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Select item 27222000

 

  1. [Arrhythmia in adults with congenital heart defects : Incidence, substrates, and mechanisms].

Wasmer K, Köbe J, Diller G, Eckardt L.

Herzschrittmacherther Elektrophysiol. 2016 May 23. [Epub ahead of print] German.

PMID: 27216033

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Select item 27217424

 

  1. Variants of Transient Receptor Potential Melastatin Member 4 in Childhood Atrioventricular Block.

Syam N, Chatel S, Ozhathil LC, Sottas V, Rougier JS, Baruteau A, Baron E, Amarouch MY, Daumy X, Probst V, Schott JJ, Abriel H.

J Am Heart Assoc. 2016 May 20;5(5). pii: e001625. doi: 10.1161/JAHA.114.001625.

PMID: 27207958 Free Article

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  1. Ventricular tachycardia in repaired congenital heart disease.

Zeppenfeld K.

Herzschrittmacherther Elektrophysiol. 2016 May 19. [Epub ahead of print]

PMID: 27193903

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Select item 27209609

 

  1. New Technique for Surgical Epicardial Implantation of a Cardioverter-Defibrillator in Children and Adults With Congenital Heart Disease.

Pospiech T, Roubertie F, Jalal Z, Bordachar P, Thambo JB.

Ann Thorac Surg. 2016 May 17. pii: S0003-4975(16)00191-0. doi: 10.1016/j.athoracsur.2016.02.015. [Epub ahead of print]

PMID: 27207391

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Select item 27184689

 

  1. Inappropriate Shocks in a Patient With Subcutaneous ICD and Transvenous Pacemaker: Is it as it Seems?

Maria SL, Anselmo SF, Letizia V, Ilaria T, Silvia P, Stefano MS, Fabrizio D.

Pacing Clin Electrophysiol. 2016 May 16. doi: 10.1111/pace.12885. [Epub ahead of print]

PMID: 27198130

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Select item 27196949

 

  1. Efficacy and Safety of Radiofrequency Catheter Ablation of Tachyarrhythmias in 123 Children Under 3 Years of Age.

Jiang HE, Li XM, Li YH, Zhang Y, Liu HJ.

Pacing Clin Electrophysiol. 2016 May 16. doi: 10.1111/pace.12888. [Epub ahead of print]

PMID: 27196949

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Select item 27055756

 

  1. Cardiac arrest in infants, children, and adolescents: long-term emotional and behavioral functioning.

van Zellem L, Utens EM, Madderom M, Legerstee JS, Aarsen F, Tibboel D, Buysse C.

Eur J Pediatr. 2016 May 14. [Epub ahead of print]

PMID: 27177532

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Select item 27189685

 

  1. Implantable cardioverter-defibrillators in adults with congenital heart disease: a systematic review and meta-analysis.

Vehmeijer JT, Brouwer TF, Limpens J, Knops RE, Bouma BJ, Mulder BJ, de Groot JR.

Eur Heart J. 2016 May 7;37(18):1439-48. doi: 10.1093/eurheartj/ehv735. Epub 2016 Feb 11. Review.

PMID: 26873095

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Select item 26843280

 

  1. The genetics underlying acquired long QT syndrome: impact for genetic screening.

Itoh H, Crotti L, Aiba T, Spazzolini C, Denjoy I, Fressart V, Hayashi K, Nakajima T, Ohno S, Makiyama T, Wu J, Hasegawa K, Mastantuono E, Dagradi F, Pedrazzini M, Yamagishi M, Berthet M, Murakami Y, Shimizu W, Guicheney P, Schwartz PJ, Horie M.

Eur Heart J. 2016 May 7;37(18):1456-64. doi: 10.1093/eurheartj/ehv695. Epub 2015 Dec 28.

PMID: 26715165

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Select item 27167020

 

  1. Incidence and characteristics of heart block after heart surgery in pediatric patients: A multicenter study.

Liberman L, Silver ES, Chai PJ, Anderson BR.

J Thorac Cardiovasc Surg. 2016 May 7. pii: S0022-5223(16)30104-0. doi: 10.1016/j.jtcvs.2016.03.081. [Epub ahead of print]

PMID: 27167020

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Select item 27150455

 

  1. A Review of Surgical Atrioventricular Block with Emphasis in Patients with Single Ventricle Physiology.

Marshall AM.

Congenit Heart Dis. 2016 May 3. doi: 10.1111/chd.12372. [Epub ahead of print]

PMID: 27139742

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Select item 27179205

 

  1. Evaluating current implantable cardioverter defibrillator implantation procedures: can common complications be minimised?

Timmers L, Van Heuverswyn F, De Wilde H, Jordaens L.

Expert Rev Cardiovasc Ther. 2016 May;14(5):579-89. doi: 10.1586/14779072.2016.1144471. Epub 2016 Feb 10.

PMID: 26790106

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Select item 26950799

 

  1. The Management of Supraventricular Tachyarrhythmias in Patients with Pulmonary Arterial Hypertension.

Małaczyńska-Rajpold K, Komosa A, Błaszyk K, Araszkiewicz A, Janus M, Olasińska-Wiśniewska A, Jankiewicz S, Mączyński M, Mularek-Kubzdela T.

Heart Lung Circ. 2016 May;25(5):442-50. doi: 10.1016/j.hlc.2015.10.008. Epub 2015 Nov 2.

PMID: 26643289

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Select item 26690060

 

  1. Minimally invasive percutaneous pericardial ICD placement in an infant piglet model: Head-to-head comparison with an open surgical thoracotomy approach.

Clark BC, Davis TD, El-Sayed Ahmed MM, McCarter R, Ishibashi N, Jordan CP, Kane TD, Kim PC, Krieger A, Nath DS, Opfermann JD, Berul CI.

Heart Rhythm. 2016 May;13(5):1096-104. doi: 10.1016/j.hrthm.2015.12.015. Epub 2015 Dec 9.

PMID: 26690060

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Select item 25656932

 

  1. Brugada syndrome and Brugada phenocopy. The importance of a differential diagnosis.

Dendramis G.

Int J Cardiol. 2016 May 1;210:25-7. doi: 10.1016/j.ijcard.2016.02.097. Epub 2016 Feb 17.

PMID: 26922708

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  1. Bipolar Versus Unipolar Temporary Epicardial Ventricular Pacing Leads Use in Congenital Heart Disease: A Prospective Randomized Controlled Study.

Mohari N, Starr JP, Gates RN, Domico MB, Batra AS.

Pacing Clin Electrophysiol. 2016 May;39(5):471-7. doi: 10.1111/pace.12836. Epub 2016 Mar 29.

PMID: 26920816

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Select item 27096879

 

  1. Implantable Loop Recorder Monitoring for Refining Management of Children With Inherited Arrhythmia Syndromes.

Avari Silva JN, Bromberg BI, Emge FK, Bowman TM, Van Hare GF.

J Am Heart Assoc. 2016 May 26;5(6). pii: e003632. doi: 10.1161/JAHA.116.003632.

PMID: 27231019 Free Article

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Select item 27229332

 

  1. Catheter Ablation of Supraventricular Tachyarrhythmia after Extracardiac Fontan Surgery.

Moore JP, Shannon KM, Fish FA, Seslar SP, Garnreiter JM, Krause U, Tanel RE, Papez AA, Pilcher TA, Balaji S.

Heart Rhythm. 2016 May 25. pii: S1547-5271(16)30320-4. doi: 10.1016/j.hrthm.2016.05.019. [Epub ahead of print]

PMID: 27236028

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  1. Inherited catecholaminergic polymorphic ventricular tachycardia due to RYR2 mutation.

Watanabe T, Ohno S, Shirai M, Endoh A, Hongo T, Ueta I, Yoshimoto J.

Pediatr Int. 2016 May 25. doi: 10.1111/ped.12910. [Epub ahead of print]

PMID: 27225049

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Select item 27089500

 

  1. What factors influence parents’ perception of the quality of life of children and adolescents with neurocardiogenic syncope?

Grimaldi Capitello T, Fiorilli C, Placidi S, Vallone R, Drago F, Gentile S.

Health Qual Life Outcomes. 2016 May 17;14(1):79. doi: 10.1186/s12955-016-0476-9.

PMID: 27188269 Free PMC Article

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  1. Catheter ablation of idiopathic right ventricular arrhythmias in children with limited fluoroscopy.

Akdeniz C, Gul EE, Celik N, Karacan M, Tuzcu V.

J Interv Card Electrophysiol. 2016 May 16. [Epub ahead of print]

PMID: 27184808

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Select item 27197083

 

  1. Cryoablation with an 8-mm-tip Catheter for Right-Sided Accessory Pathways in Children.

Tanidir IC, Ergul Y, Ozturk E, Dalgic F, Kiplapinar N, Tola HT, Akdeniz C, Tuzcu V.

Pacing Clin Electrophysiol. 2016 May 16. doi: 10.1111/pace.12892. [Epub ahead of print]

PMID: 27197083

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Select item 27196949

 

  1. Efficacy and Safety of Radiofrequency Catheter Ablation of Tachyarrhythmias in 123 Children Under 3 Years of Age.

Jiang HE, Li XM, Li YH, Zhang Y, Liu HJ.

Pacing Clin Electrophysiol. 2016 May 16. doi: 10.1111/pace.12888. [Epub ahead of print]

PMID: 27196949

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Select item 27032711

 

  1. In Hypertrophic Cardiomyopathy, the Spatial Peaks QRS-T Angle Identifies Those With Sustained Ventricular Arrhythmias.

Cortez D, Graw S, Mestroni L.

Clin Cardiol. 2016 May 13. doi: 10.1002/clc.22549. [Epub ahead of print]

PMID: 27175825 Free Article

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Select item 27232916

 

  1. Flecainide vs digoxin for fetal supraventricular tachycardia: Comparison of 2 drug protocols.

Van Hare GF.

Heart Rhythm. 2016 May 6. pii: S1547-5271(16)30146-1. doi: 10.1016/j.hrthm.2016.03.045. [Epub ahead of print] No abstract available.

PMID: 27161605

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  1. Evaluation of P-Wave Dispersion, Diastolic Function, and Atrial Electromechanical Conduction in Pediatric Patients with Subclinical Hypothyroidism.

Irdem A, Aydın Sahin D, Kervancioglu M, Baspinar O, Sucu M, Keskin M, Kilinc M.

Echocardiography. 2016 May 5. doi: 10.1111/echo.13255. [Epub ahead of print]

PMID: 27146071

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Select item 27151913

 

  1. Sphingomonas paucimobilis causing pacemaker pocket infection in a pediatric patient with a hemangioma.

Shi X, Liu R.

Am J Infect Control. 2016 May 1;44(5):617-8. doi: 10.1016/j.ajic.2015.11.023. Epub 2016 Jan 15. No abstract available.

PMID: 26781221

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Select item 27123632

 

  1. Amiodarone toxicity: An underdiagnosed entity.

Xavier J, Haranal MY, Reddy SR, Melagiriyappa S.

Ann Pediatr Cardiol. 2016 May-Aug;9(2):199-200. doi: 10.4103/0974-2069.180671. No abstract available.

PMID: 27212866 Free PMC Article

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Select item 27212863

 

  1. Cardiac autonomic functions in children with familial Mediterranean fever.

Şahin M, Kır M, Makay B, Keskinoğlu P, Bora E, Ünsal E, Ünal N.

Clin Rheumatol. 2016 May;35(5):1237-44. doi: 10.1007/s10067-014-2714-z. Epub 2014 Jun 15.

PMID: 24928342

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Select item 27002620

 

  1. Increased P-wave dispersion a risk for atrial fibrillation in adolescents with anorexia nervosa.

Ertuğrul İ, Akgül S, Derman O, Karagöz T, Kanbur N.

Eat Disord. 2016 May-Jun;24(3):289-96. doi: 10.1080/10640266.2015.1042310. Epub 2015 May 18.

PMID: 25985103

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Select item 27132629

 

  1. D117N in Cypher/ZASP may not be a causative mutation for dilated cardiomyopathy and ventricular arrhythmias.

Levitas A, Konstantino Y, Muhammad E, Afawi Z, Marc Weinstein J, Amit G, Etzion Y, Parvari R.

Eur J Hum Genet. 2016 May;24(5):666-71. doi: 10.1038/ejhg.2015.195. Epub 2015 Sep 30.

PMID: 26419279

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Select item 26833052

 

  1. Pediatric &amp; Congenital Electrophysiology Society: building an international paediatric electrophysiology organisation.

Cohen M, Sanatani S, Stephenson E, Skinner J, Drago F, Davis A, Janousek J, Rosenthal E, Collins KK, Triedman J.

Heart Rhythm. 2016 May;13(5):1006-9. doi: 10.1016/j.hrthm.2016.01.013. Epub 2016 Apr 16.

PMID: 27090729

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Select item 26690060

 

  1. Contribution of TGFB1 and TNF-α genes in one of twin pregnancies with congenital complete heart block phenotype.

Bornaun H, Oztarhan K, Ocak Z, Ekiz A, Ulucan K, Buyukkale G, Gedikbasi A.

Int J Cardiol. 2016 May 1;210:16-8. doi: 10.1016/j.ijcard.2016.01.214. Epub 2016 Feb 13. No abstract available.

PMID: 26922706

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Select item 26780661

 

  1. MYBPC3 hypertrophic cardiomyopathy can be detected by using advanced ECG in children and young adults.

Fernlund E, Liuba P, Carlson J, Platonov PG, Schlegel TT.

J Electrocardiol. 2016 May-Jun;49(3):392-400. doi: 10.1016/j.jelectrocard.2016.03.001. Epub 2016 Mar 14.

PMID: 27061026

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Select item 27197775

 

  1. Availability of Automated External Defibrillators in Public High Schools.

White MJ, Loccoh EC, Goble MM, Yu S, Duquette D, Davis MM, Odetola FO, Russell MW.

J Pediatr. 2016 May;172:142-146.e1. doi: 10.1016/j.jpeds.2016.02.010. Epub 2016 Feb 28.

PMID: 26935784

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Select item 26891888

 

  1. Arrhythmic Burden and Ambulatory Monitoring of Pediatric Patients with Cardiomyopathy.

Czosek RJ, Jefferies JL, Khoury PR, Anderson JB, Wilmot I, Knilans TK, Spar DS.

Pacing Clin Electrophysiol. 2016 May;39(5):443-51. doi: 10.1111/pace.12835. Epub 2016 Mar 28.

PMID: 26935486

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Select item 26920816

 

  1. Catecholaminergic polymorphic ventricular tachycardia: An exciting new era.

Behere SP, Weindling SN.

Ann Pediatr Cardiol. 2016 May-Aug;9(2):137-46. doi: 10.4103/0974-2069.180645. Review.

PMID: 27212848 Free PMC Article

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